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  1. Article ; Online: Key roles of the cytotechnologists and biomedical scientists in interventional pathology: The foundation of a seamless workflow.

    Del Mar Olmo Fernandez, Maria / Wheeldon, Leonie / Villar-Zarra, Karen

    Cytopathology : official journal of the British Society for Clinical Cytology

    2024  

    Abstract: This paper delves into the integral role of cytotechnologists (CTs) and biomedical scientists (BMSs) in interventional pathology, emphasizing their multifaceted responsibilities. From meticulous pre-procedural preparations to real-time decision-making ... ...

    Abstract This paper delves into the integral role of cytotechnologists (CTs) and biomedical scientists (BMSs) in interventional pathology, emphasizing their multifaceted responsibilities. From meticulous pre-procedural preparations to real-time decision-making and post-procedural care, CTs/BMSs significantly contribute to diagnostic efficiency. Their involvement is critical in optimizing patient outcomes.
    Language English
    Publishing date 2024-03-22
    Publishing country England
    Document type Editorial
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.13375
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    Zs.A 2926: Show issues Location:
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  2. Article ; Online: Antithrombotic therapy-A simple algorithm for the interventional pathologist: A case series.

    Villar-Zarra, Karen / Nieves-Alonso, Jesús / Torres-Rivas, Héctor-Enrique

    Cytopathology : official journal of the British Society for Clinical Cytology

    2024  

    Abstract: We can safely manage patients on antithrombotic therapy in the interventional pathology practice with this practical algorithm based on the new Antithrombotic Therapy Management Guidelines. This new algorithm helps ensure safe care for patients on ... ...

    Abstract We can safely manage patients on antithrombotic therapy in the interventional pathology practice with this practical algorithm based on the new Antithrombotic Therapy Management Guidelines. This new algorithm helps ensure safe care for patients on antithrombotic therapy undergoing interventional pathology procedures. #interventionalpathology.
    Language English
    Publishing date 2024-03-25
    Publishing country England
    Document type Editorial
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.13377
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    Zs.A 2926: Show issues Location:
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  3. Article ; Online: Interventional pathology: One small step for the pathologist, one big leap for the speciality.

    Nieto Llanos, Santiago / Villar Zarra, Karen

    Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

    2022  Volume 55, Issue 2, Page(s) 73–76

    MeSH term(s) Humans ; Pathologists ; Research
    Language English
    Publishing date 2022-04-26
    Publishing country Spain
    Document type Editorial
    ZDB-ID 2463888-2
    ISSN 1988-561X ; 1988-561X
    ISSN (online) 1988-561X
    ISSN 1988-561X
    DOI 10.1016/j.patol.2022.03.001
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  4. Article ; Online: Resident training in interventional pathology: Ultrasound-guided fine-needle aspiration and rapid on site evaluation-5 years of teaching experience in a single university hospital.

    Torres-Rivas, Héctor-Enrique / Fernández Fernández, Luis Manuel / González Gutiérrez, María de la Paz / Berríos Hernández, Mario Luis / Pérez Fontán, José Fernando / Chandra, Ashish / Caputo, Alessandro / Dávila Lemos, Ana Belén / Villar Zarra, Karen

    Cytopathology : official journal of the British Society for Clinical Cytology

    2024  

    Abstract: Introduction: Despite the established role of the interventional pathologist, their diagnostic performance is difficult to establish. At least in Spain training of pathology residents in ultrasound-guided interventional procedures for specimen ... ...

    Abstract Introduction: Despite the established role of the interventional pathologist, their diagnostic performance is difficult to establish. At least in Spain training of pathology residents in ultrasound-guided interventional procedures for specimen collection is limited or absent in most institutions. We present our teaching experience in the instruction of ultrasound-guided fine-needle aspiration (FNA) to pathology residents in a tertiary-level hospital.
    Materials and methods: The training of pathology residents who rotated through the interventional unit of the pathology department and the application of ultrasound-guided FNA and rapid on-site evaluation (U-ROSE) was documented over 5 years. The training period was broken down into learning phases and included the number of ultrasound-guided FNA performed, anatomical location, and their diagnostic performance, among other aspects.
    Results: Nineteen (19) pathology residents were trained in U-ROSE, and performed a total of 4003 procedures, with a mean of 211 per resident. In 53% of cases only one pass was required for an adequated sample. The specimen was diagnostic in more than 97% of cases. The most frequently sampled anatomical sites were the thyroid gland (n = 2347), followed by lymph node (n = 667), soft tissues (n = 663) and salivary glands (n = 322).
    Conclusion: The results support the training programme followed by pathology residents in learning U-ROSE, which is essential to lay the foundations for the future interventional pathologist.
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.13355
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    Zs.A 2926: Show issues Location:
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  5. Article ; Online: Histopathologic study of paradoxical psoriasis induced by antitumor necrosis factor alpha therapy: Is it true psoriasis?

    Navarro, Raquel / Villar-Zarra, Karen / Juarez, África / Daudén, Esteban

    Journal of cutaneous pathology

    2020  Volume 48, Issue 6, Page(s) 813–816

    MeSH term(s) Adalimumab/adverse effects ; Adult ; Aged ; Biopsy/methods ; Case-Control Studies ; Etanercept/adverse effects ; Female ; Humans ; Inflammatory Bowel Diseases/drug therapy ; Inflammatory Bowel Diseases/epidemiology ; Infliximab/adverse effects ; Male ; Middle Aged ; Prevalence ; Psoriasis/chemically induced ; Psoriasis/epidemiology ; Psoriasis/pathology ; Retrospective Studies ; Rheumatic Diseases/drug therapy ; Rheumatic Diseases/epidemiology ; Skin/pathology ; Tumor Necrosis Factor Inhibitors/adverse effects ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/immunology
    Chemical Substances Tumor Necrosis Factor Inhibitors ; Tumor Necrosis Factor-alpha ; Infliximab (B72HH48FLU) ; Adalimumab (FYS6T7F842) ; Etanercept (OP401G7OJC)
    Language English
    Publishing date 2020-12-02
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.13919
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    Zs.A 1043: Show issues Location:
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  6. Article ; Online: Tumor de células claras «sugar tumor» pulmonar. Neoplasia de diagnóstico inusual.

    Torres Rivas, Héctor Enrique / Fernández Fernández, Luis Manuel / Villar Zarra, Karen / Ugalde Herrá, Rodrigo

    Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

    2020  Volume 55 Suppl 1, Page(s) S39–S43

    Abstract: Clear Cell «sugar tumor» of the lung is a rare nosological entity of which around 60 cases have been published in the scientific literature. Considered to be of mesenchymal origin, it presents a typical histochemical - immunohistochemical profile, ... ...

    Title translation Lung clear cell tumor «sugar tumor». Unusual diagnostic neoplasm.
    Abstract Clear Cell «sugar tumor» of the lung is a rare nosological entity of which around 60 cases have been published in the scientific literature. Considered to be of mesenchymal origin, it presents a typical histochemical - immunohistochemical profile, positive PAS and melanic markers, which allows it to be differentiated from other more frequent neoplasms with worse prognosis. We present the case of a 56-year-old man with a clear cell lung tumor. Radiological, macro-microscopic and histochemistry - immunohistochemical characterization, as well as a brief review of the literature.
    MeSH term(s) Humans ; Lung/pathology ; Lung Neoplasms/diagnosis ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neuroendocrine Tumors ; Perivascular Epithelioid Cell Neoplasms/diagnosis ; Prognosis ; Sugars
    Chemical Substances Sugars
    Language Spanish
    Publishing date 2020-08-03
    Publishing country Spain
    Document type Case Reports ; Review
    ZDB-ID 2463888-2
    ISSN 1988-561X ; 1988-561X
    ISSN (online) 1988-561X
    ISSN 1988-561X
    DOI 10.1016/j.patol.2020.06.004
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  7. Article ; Online: Amyloid goiter diagnosis by ultrasound-guided fine needle aspiration performed by interventional pathologist.

    Celis Pinto, Juan Carlos / Torres-Rivas, Héctor-Enrique / Fernández Fernández, Luis Manuel / Villar Zarra, Karen / de la Paz González Gutiérrez, María

    Diagnostic cytopathology

    2020  Volume 49, Issue 3, Page(s) E137–E140

    Abstract: Amyloid goiter (AG) (primary or secondary) is extremely rare. An abdominal fat pad core needle biopsy (CNB) is the diagnostic gold standard for secondary amyloidosis. Although CNB is useful to detect amyloid infiltration of a specific organ, fine-needle ... ...

    Abstract Amyloid goiter (AG) (primary or secondary) is extremely rare. An abdominal fat pad core needle biopsy (CNB) is the diagnostic gold standard for secondary amyloidosis. Although CNB is useful to detect amyloid infiltration of a specific organ, fine-needle aspiration (FNA) is proven to be the best diagnostic method for thyroid disorders. Guidelines recommend an ultrasound-guided FNA (US-FNA) whenever possible. This procedure is usually performed by various interventional specialists, including pathologists, who perform the procedure in addition to validating the adequacy of the sample. We report a rare case of AG diagnosed using US-FNA performed by a pathologist in a 39-year-old patient with systemic amyloidosis. US-FNA performed by pathologists is a proven, less-invasive, and cost-effective tool that ensures acquisition of adequate specimens and reduces nondiagnostic rates of this procedure to ensure timely cytological diagnosis.
    MeSH term(s) Adult ; Amyloidosis/diagnosis ; Amyloidosis/pathology ; Biopsy, Fine-Needle/methods ; Goiter/diagnosis ; Goiter/pathology ; Humans ; Male ; Pathologists ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/pathology ; Thyroid Nodule/diagnosis ; Thyroid Nodule/pathology ; Ultrasonography/methods ; Ultrasonography, Interventional/methods
    Language English
    Publishing date 2020-09-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632710-2
    ISSN 1097-0339 ; 8755-1039
    ISSN (online) 1097-0339
    ISSN 8755-1039
    DOI 10.1002/dc.24625
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    Zs.A 2117: Show issues Location:
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  8. Article ; Online: Systematized protocol for interventional pathology reports. Pathology report paradigm for pathologist-performed Ultrasound Guided Fine Needle Aspiration (USFNA) and Ultrasound Guided Core Needle Biopsy (USCNB).

    Villar Zarra, Karen / Torres Rivas, Héctor Enrique / Rollins, Susan D / Fernández Fernández, Luis Manuel / Nieto Llanos, Santiago

    Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

    2019  Volume 52, Issue 3, Page(s) 163–166

    MeSH term(s) Biopsy, Fine-Needle/methods ; Biopsy, Large-Core Needle/methods ; Humans ; Image-Guided Biopsy ; Practice Guidelines as Topic ; Research Report/standards ; Ultrasonography, Interventional
    Language English
    Publishing date 2019-03-16
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2463888-2
    ISSN 1988-561X ; 1699-8855
    ISSN (online) 1988-561X
    ISSN 1699-8855
    DOI 10.1016/j.patol.2019.01.008
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  9. Article ; Online: Unclassifiable CD20-negative Testicular Diffuse Large B-cell Lymphoma.

    Garrido-Abad, Pablo / García-Martín, Luis / Villar-Zarra, Karen / Díaz-Menéndez, Ariel / Fernández-Arjona, Manuel

    Urology

    2018  Volume 117, Page(s) e3–e4

    Abstract: CD20-negative diffuse large B-cell lymphoma (DLBCL) is a very uncommon neoplasm, and very rare unclassifiable cases that did not meet the criteria for well-established subtypes of CD20-negative DLBCLs have been reported. CD20-negative DLBCLs often ... ...

    Abstract CD20-negative diffuse large B-cell lymphoma (DLBCL) is a very uncommon neoplasm, and very rare unclassifiable cases that did not meet the criteria for well-established subtypes of CD20-negative DLBCLs have been reported. CD20-negative DLBCLs often present an aggressive clinical course with important chemoresistance and poor prognosis. Here, we report a case of CD20-negative DLBCL presented as a testicular mass. To the best of our knowledge, this is one of the first reported cases of testicular unclassifiable CD20-negative DLBCL.
    MeSH term(s) Aged, 80 and over ; Antigens, CD20/metabolism ; Humans ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Lymphoma, Large B-Cell, Diffuse/pathology ; Male ; Testicular Neoplasms/metabolism ; Testicular Neoplasms/pathology
    Chemical Substances Antigens, CD20
    Language English
    Publishing date 2018-04-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2018.04.019
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    Zs.A 1142: Show issues Location:
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    Zs.MO 275: Show issues

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  10. Article ; Online: Biopsia percutánea muscular mínimamente invasiva realizada por patólogo intervencionista en el estudio de miopatías. Veinte años de experiencia.

    Torres Rivas, Héctor Enrique / Villar Zarra, Karen / Fernández Fernández, Luis Manuel / Posada Mesa, Luisa / Fernández Vega, Iván / González Gutiérrez, María de la Paz / Gómez Martín, Ángel / Astudillo González, Aurora

    Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

    2020  Volume 54, Issue 3, Page(s) 156–164

    Abstract: Introduction: Muscle biopsy plays a major role in the final diagnosis of myopathies. Open muscle biopsy is the benchmark procedure, although minimally invasive percutaneous muscle biopsy (MIPMB) has demonstrated comparable diagnostic performance at a ... ...

    Title translation Minimally invasive percutaneous musculoskeletal biopsy performed by Interventional Pathologist for myopathy study. Twenty years of experience.
    Abstract Introduction: Muscle biopsy plays a major role in the final diagnosis of myopathies. Open muscle biopsy is the benchmark procedure, although minimally invasive percutaneous muscle biopsy (MIPMB) has demonstrated comparable diagnostic performance at a lower cost and can be carried out by interventional pathologists.
    Materials and methods: Muscle biopsies performed from 1997 to 2017 were reviewed and classified according to the type of procedure, whether carried out by an interventional pathologist or another specialist, the diagnosis and the effectiveness of the procedure.
    Results: 738 muscle biopsies were performed; 32% were open biopsies and 68% MIPMB carried out by pathologist. The muscle most often biopsied was the femoral quadriceps and the most frequent diagnosis was inflammatory myopathies. In only 39 cases (20 open biopsies and 19 MIPMB) was there insufficient tissue for diagnosis.
    Conclusions: Muscle biopsy proved highly effective as a diagnostic tool as 90% yielded adequate tissue samples. The results obtained with MIPMB performed by interventionist pathologists were comparable to those of open muscle biopsy.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biopsy, Large-Core Needle/adverse effects ; Biopsy, Large-Core Needle/methods ; Child ; Child, Preschool ; Clinical Competence ; Female ; Humans ; Infant ; Male ; Middle Aged ; Muscle, Skeletal/pathology ; Muscular Diseases/pathology ; Pathologists/standards ; Quadriceps Muscle/pathology ; Time Factors ; Young Adult
    Language Spanish
    Publishing date 2020-12-13
    Publishing country Spain
    Document type Comparative Study ; Journal Article
    ZDB-ID 2463888-2
    ISSN 1988-561X ; 1988-561X
    ISSN (online) 1988-561X
    ISSN 1988-561X
    DOI 10.1016/j.patol.2020.10.002
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