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  1. Article ; Online: Long-Term Exposure to Ambient Benzene and Mortality.

    Villeneuve, Paul J

    American journal of respiratory and critical care medicine

    2024  Volume 209, Issue 8, Page(s) 905–906

    MeSH term(s) Humans ; Benzene/toxicity ; Benzene/analysis ; Environmental Exposure/adverse effects ; Environmental Exposure/analysis ; Air Pollutants/adverse effects ; Air Pollutants/analysis
    Chemical Substances Benzene (J64922108F) ; Air Pollutants
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202401-0005ED
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  2. Article ; Online: Re: exposure to phenoxyacetic acids and glyphosate as risk factors for non-Hodgkin lymphoma.

    Villeneuve, Paul J / Harris, Shelley A

    Leukemia & lymphoma

    2024  Volume 65, Issue 1, Page(s) 138–140

    MeSH term(s) Humans ; Glyphosate ; Lymphoma, Non-Hodgkin/epidemiology ; Lymphoma, Non-Hodgkin/etiology ; Risk Factors ; Acetates/adverse effects ; Case-Control Studies
    Chemical Substances Glyphosate (4632WW1X5A) ; phenoxyacetic acid (YRC253429Q) ; Acetates
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.1080/10428194.2023.2275529
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  3. Article ; Online: Updated Analysis of Radon Exposure and Lung Cancer Mortality in the Cohort of Newfoundland Fluorspar Miners (1950-2016).

    Villeneuve, Paul J / Morrison, Howard I / Lane, Rachel

    Radiation research

    2024  

    Abstract: The commercial mining of fluorspar in St. Lawrence Newfoundland began in 1933. Miners who worked underground were exposed to high levels of radon progeny, especially before ventilation was introduced into the mines in 1960. The mean cumulative radon ... ...

    Abstract The commercial mining of fluorspar in St. Lawrence Newfoundland began in 1933. Miners who worked underground were exposed to high levels of radon progeny, especially before ventilation was introduced into the mines in 1960. The mean cumulative radon exposure for underground miners in this cohort was 380.9 working level months (WLM). A series of studies of this cohort have characterized the increased risks of lung cancer mortality due to radon. We have extended the follow-up of this cohort an additional 15 years to provide additional insights on the risks of low levels of radon exposure, and the modifying effects of time since exposure, age at first exposure, attained age, duration of exposure, and cigarette smoking. The cohort consisted of 1,735 underground and 315 male surface miners who, combined, accrued 81,650 person-years of follow-up. The mortality experience of the cohort was determined from 1950-2016 through record linkage to Canadian national death data. Individual-level estimates of exposure to radon progeny, in WLMs, were determined for each year of employment. We compared the mortality experience of the underground miners to Newfoundland men using the standardized mortality ratio (SMR). Poisson regression models were fit to estimate excess relative risks (ERR) per 100 WLM. There were 236 lung cancer deaths identified, and of these, 221 occurred among underground workers. The SMR for lung cancer among underground miners compared to Newfoundland men was 2.67 (95% CI: 2.33, 3.04). The ERR per 100 WLM for lung cancer mortality, assuming a 5-year exposure lag, was 0.41 (95% CI: 0.23, 0.59). Attained age and time since exposure were important modifiers to the radon-lung cancer relationship. The joint relationship between smoking and radon on lung cancer risk was sub-additive, however, the smoking data were limited and available for only half of the cohort.
    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80322-4
    ISSN 1938-5404 ; 0033-7587
    ISSN (online) 1938-5404
    ISSN 0033-7587
    DOI 10.1667/RADE-23-00114.1
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  4. Article ; Online: Ecological studies of COVID-19 and air pollution: How useful are they?

    Villeneuve, Paul J / Goldberg, Mark S

    Environmental epidemiology (Philadelphia, Pa.)

    2022  Volume 6, Issue 1, Page(s) e195

    Abstract: Background: Results from ecological studies have suggested that air pollution increases the risk of developing and dying from COVID-19. Drawing causal inferences from the measures of association reported in ecological studies is fraught with challenges ... ...

    Abstract Background: Results from ecological studies have suggested that air pollution increases the risk of developing and dying from COVID-19. Drawing causal inferences from the measures of association reported in ecological studies is fraught with challenges given biases arising from an outcome whose ascertainment is incomplete, varies by region, time, and across sociodemographic characteristics, and cannot account for clustering or within-area heterogeneity. Through a series of analyses, we illustrate the dangers of using ecological studies to assess whether ambient air pollution increases the risk of dying from, or transmitting, COVID-19.
    Methods: We performed an ecological analysis in the continental United States using county-level ambient concentrations of fine particulate matter (PM
    Results: Our analyses revealed that the shape of the exposure-response curve between PM
    Conclusions: Our analyses indicated that ecological analyses are prone to showing spurious relationships between ambient air pollution and mortality from COVID-19 as well as the prevalence of HIV. We discuss the many potential biases inherent in any ecological-based analysis of air pollution and COVID-19.
    Language English
    Publishing date 2022-02-04
    Publishing country United States
    Document type Journal Article
    ISSN 2474-7882
    ISSN (online) 2474-7882
    DOI 10.1097/EE9.0000000000000195
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  5. Article ; Online: Invited Perspective: Studying Walkability and Cancer Incidence-A Step in the Right Direction.

    Roscoe, Charlotte / Hu, Cindy R / Villeneuve, Paul J

    Environmental health perspectives

    2023  Volume 131, Issue 10, Page(s) 101301

    MeSH term(s) Humans ; Incidence ; Walking ; Neoplasms/epidemiology ; Residence Characteristics ; Environment Design
    Language English
    Publishing date 2023-10-04
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 195189-0
    ISSN 1552-9924 ; 0091-6765 ; 1078-0475
    ISSN (online) 1552-9924
    ISSN 0091-6765 ; 1078-0475
    DOI 10.1289/EHP13695
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  6. Article ; Online: Perspectives on the future of occupational epidemiology in Canada.

    Villeneuve, Paul J / Parent, Marie-Élise

    Canadian journal of public health = Revue canadienne de sante publique

    2021  Volume 112, Issue 5, Page(s) 787–790

    Title translation Perspectives sur l’avenir de l’épidémiologie du travail au Canada.
    MeSH term(s) Canada/epidemiology ; Forecasting ; Humans ; Occupational Diseases/epidemiology
    Language English
    Publishing date 2021-10-12
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 417262-0
    ISSN 1920-7476 ; 0008-4263
    ISSN (online) 1920-7476
    ISSN 0008-4263
    DOI 10.17269/s41997-021-00573-w
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  7. Article ; Online: Invited Perspective: Ambient Air Pollution and SARS-CoV-2: Research Challenges and Public Health Implications.

    Hansell, Anna L / Villeneuve, Paul J

    Environmental health perspectives

    2021  Volume 129, Issue 11, Page(s) 111303

    MeSH term(s) Air Pollution/adverse effects ; Air Pollution/analysis ; COVID-19 ; Humans ; Particulate Matter ; Public Health ; SARS-CoV-2
    Chemical Substances Particulate Matter
    Language English
    Publishing date 2021-11-19
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 195189-0
    ISSN 1552-9924 ; 0091-6765 ; 1078-0475
    ISSN (online) 1552-9924
    ISSN 0091-6765 ; 1078-0475
    DOI 10.1289/EHP10540
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  8. Article ; Online: Re: Links between air pollution and COVID-19 in England.

    Villeneuve, Paul J / Goldberg, Mark S

    Environmental pollution (Barking, Essex : 1987)

    2021  Volume 274, Page(s) 116576

    MeSH term(s) Air Pollutants/analysis ; Air Pollution/analysis ; COVID-19 ; England ; Humans ; Particulate Matter/analysis ; SARS-CoV-2
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2021-01-27
    Publishing country England
    Document type Letter
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2021.116576
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  9. Article ; Online: Re: Long-term exposure to air-pollution and COVID-19 mortality in England: A hierarchical spatial analysis Long-term exposure to air-pollution and COVID-19 mortality in England: A hierarchical spatial analysis (Environment International 146 (2021) 106316).

    Goldberg, Mark S / Villeneuve, Paul J

    Environment international

    2021  Volume 150, Page(s) 106422

    MeSH term(s) Air Pollution ; COVID-19 ; England/epidemiology ; Humans ; Particulate Matter/analysis ; SARS-CoV-2 ; Spatial Analysis
    Chemical Substances Particulate Matter
    Language English
    Publishing date 2021-02-03
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 554791-x
    ISSN 1873-6750 ; 0160-4120
    ISSN (online) 1873-6750
    ISSN 0160-4120
    DOI 10.1016/j.envint.2021.106422
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  10. Article ; Online: Residential surrounding greenness and the incidence of childhood asthma: Findings from a population-based cohort in Ontario, Canada.

    Mansouri, Razieh / Lavigne, Eric / Talarico, Robert / Smargiassi, Audrey / Rodriguez-Villamizar, Laura A / Villeneuve, Paul J

    Environmental research

    2024  Volume 249, Page(s) 118316

    Abstract: Several epidemiological studies have investigated the possible role that living in areas with greater amounts of greenspace has on the incidence of childhood asthma. These findings have been inconsistent, and few studies explored the relevance of timing ... ...

    Abstract Several epidemiological studies have investigated the possible role that living in areas with greater amounts of greenspace has on the incidence of childhood asthma. These findings have been inconsistent, and few studies explored the relevance of timing of exposure. We investigated the role of residential surrounding greenness on the risk of incident asthma using a population-based retrospective cohort study. We included 982,131 singleton births in Ontario, Canada between 2006 and 2013. Two measures of greenness, the Normalized Difference Vegetation Index (NDVI) and the Green View Index (GVI), were assigned to the residential histories of these infants from pregnancy through to 12 years of age. Longitudinally-based diagnoses of asthma were determined by using provincial administrative health data. The extended Cox hazards model was used to characterize associations between greenness measures and asthma (up to age 12 years) while adjusting for several risk factors. In a fully adjusted model, that included a term for traffic-related air pollution (NO
    MeSH term(s) Humans ; Asthma/epidemiology ; Ontario/epidemiology ; Child ; Incidence ; Female ; Male ; Child, Preschool ; Infant ; Retrospective Studies ; Infant, Newborn ; Residence Characteristics ; Environmental Exposure/adverse effects ; Air Pollution/adverse effects ; Air Pollution/analysis ; Air Pollutants/analysis ; Cohort Studies
    Chemical Substances Air Pollutants
    Language English
    Publishing date 2024-01-30
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2024.118316
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