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  1. Article ; Online: Liposomal-encapsulated doxorubicin supercharge-containing front-line treatment improves response rates in primary mediastinal large B-cell lymphoma and mediastinal gray zone lymphoma.

    Picardi, Marco / Giordano, Claudia / Pugliese, Novella / Mascolo, Massimo / Varricchio, Silvia / Troncone, Giancarlo / Vigliar, Elena / Bellavicine, Claudio / Lamagna, Martina / Lisi, Dario / Vincenzi, Annamaria / Pane, Fabrizio

    publication RETRACTED

    Hematological oncology

    2024  Volume 42, Issue 1, Page(s) e3247

    MeSH term(s) Humans ; Lymphoma, B-Cell/pathology ; Doxorubicin/therapeutic use ; Polyethylene Glycols/therapeutic use ; Mediastinal Neoplasms/pathology ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/pathology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
    Chemical Substances liposomal doxorubicin ; Doxorubicin (80168379AG) ; Polyethylene Glycols (3WJQ0SDW1A)
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Letter ; Retracted Publication
    ZDB-ID 604884-5
    ISSN 1099-1069 ; 0278-0232
    ISSN (online) 1099-1069
    ISSN 0278-0232
    DOI 10.1002/hon.3247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1816: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Liquid biopsy: A promising tool for driving strategies and predicting failures in patients with classic Hodgkin lymphoma.

    Pepe, Francesco / Giordano, Claudia / Russo, Gianluca / Palumbo, Lucia / Vincenzi, Annamaria / Acanfora, Gennaro / Lisi, Dario / Picardi, Marco / Pane, Fabrizio / Troncone, Giancarlo / Vigliar, Elena

    Cytopathology : official journal of the British Society for Clinical Cytology

    2023  Volume 35, Issue 2, Page(s) 182–187

    Abstract: Classic Hodgkin lymphoma (cHL) consists of a heterogeneous group of haematological disorders that covers undifferentiated B cell neoplasms originating from germinal centre B cells. The HL molecular characterization still represents an ongoing challenge ... ...

    Abstract Classic Hodgkin lymphoma (cHL) consists of a heterogeneous group of haematological disorders that covers undifferentiated B cell neoplasms originating from germinal centre B cells. The HL molecular characterization still represents an ongoing challenge due to the low fraction of tumour Hodgkin and Reed-Sternberg cells mixed with a plethora of non-tumour haematological cells. In this scenario, next generation sequencing of liquid biopsy samples is emerging as a useful tool in HL patients' management. In this review, we aimed to overview the clinical and methodological topics regarding the implementation of molecular analysis in cHL, focusing on the role of liquid biopsy in diagnosis, follow-up, and response prediction.
    MeSH term(s) Humans ; Hodgkin Disease/diagnosis ; Hodgkin Disease/pathology ; Reed-Sternberg Cells/pathology ; Lymphoma, B-Cell/pathology ; Liquid Biopsy ; Biopsy
    Language English
    Publishing date 2023-06-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.13255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2926: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: New scenarios in Vacuoles, E1 enzyme, X linked, Autoinflammatory, Somatic (VEXAS) syndrome: Evolution from myelodysplastic syndrome to acute myeloid leukemia.

    Battipaglia, Giorgia / Vincenzi, Annamaria / Falconi, Giulia / Fiore, Alessia / D'Agostino, Francesco / Iannotta, Raffaella / Grimaldi, Francesco / Gurnari, Carmelo / Galossi, Elisa / Crisà, Elena / Bonello, Francesca / Scalia, Giulia / Izzo, Barbara / Voso, Maria Teresa / Pane, Fabrizio

    Current research in translational medicine

    2023  Volume 71, Issue 2, Page(s) 103386

    MeSH term(s) Humans ; Vacuoles ; Myelodysplastic Syndromes/genetics ; Leukemia, Myeloid, Acute/genetics ; Syndrome
    Language English
    Publishing date 2023-02-26
    Publishing country France
    Document type Letter
    ISSN 2452-3186
    ISSN (online) 2452-3186
    DOI 10.1016/j.retram.2023.103386
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Lamivudine 24-month-long prophylaxis is a safe and efficient choice for the prevention of hepatitis B virus reactivation in HBsAg-negative/HBcAb-positive patients with advanced DLBCL undergoing upfront R-CHOP-21.

    Giordano, Claudia / Picardi, Marco / Pugliese, Novella / Vincenzi, Annamaria / Abagnale, Davide Pio / De Fazio, Laura / Giannattasio, Maria Luisa / Fatigati, Carmina / Ciriello, Mauro / Salemme, Alessia / Muccioli Casadei, Giada / Vigliar, Elena / Mascolo, Massimo / Troncone, Giancarlo / Pane, Fabrizio

    Frontiers in oncology

    2023  Volume 13, Page(s) 1130899

    Abstract: Introduction: Occult hepatitis B infection (OBI) is a condition where replication-competent hepatitis B virus-DNA (HBV-DNA) is present in the liver, with or without HBV-DNA in the blood [<200 international units (IU)/ml or absent] in HB surface antigen ( ...

    Abstract Introduction: Occult hepatitis B infection (OBI) is a condition where replication-competent hepatitis B virus-DNA (HBV-DNA) is present in the liver, with or without HBV-DNA in the blood [<200 international units (IU)/ml or absent] in HB surface antigen (HBsAg)-negative/HB core antibody (HBcAb)-positive individuals. In patients with advanced stage diffuse large B-cell lymphoma (DLBCL) undergoing 6 cycles of R-CHOP-21+2 additional R, OBI reactivation is a frequent and severe complication. There is no consensus among recent guidelines on whether a pre-emptive approach or primary antiviral prophylaxis is the best solution in this setting of patients. In addition, questions still unresolved are the type of prophylactic drug against HBV and adequate prophylaxis duration.
    Methods: In this case-cohort study, we compared a prospective series of 31 HBsAg-/HBcAb+ patients with newly diagnosed high-risk DLBCL receiving lamivudine (LAM) prophylaxis 1 week before R-CHOP-21+2R until 18 months after (24-month LAM series) versus 96 HBsAg-/HBcAb+ patients (from January 2005 to December 2011) undergoing a pre-emptive approach (pre-emptive cohort) and versus 60 HBsAg-/HBcAb+ patients, from January 2012 to December 2017, receiving LAM prophylaxis [1 week before immunochemotherapy (ICHT) start until 6 months after] (12-month LAM cohort). Efficacy analysis focused primarily on ICHT disruption and secondarily on OBI reactivation and/or acute hepatitis.
    Results: In the 24-month LAM series and in the 12-month LAM cohort, there were no episodes of ICHT disruption versus 7% in the pre-emptive cohort (
    Discussion: This is the first study collecting data regarding a consistent and homogeneous large sample of 187 HBsAg-/HBcAb+ patients undergoing standard R-CHOP-21 for aggressive lymphoma. In our study, 24-month-long prophylaxis with LAM appears to be the most effective approach with a null risk of OBI reactivation, hepatitis flare-up, and ICHT disruption.
    Language English
    Publishing date 2023-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1130899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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