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  1. Article: Novoe sredstvo dlia profilaktiki opukholeĭ mochevogo puzyria.

    Pliss, G B / Vlasov, N N

    Voprosy onkologii

    1996  Volume 42, Issue 2, Page(s) 68–73

    Abstract: An experimental study of urinary bladder tumor in rats has demonstrated that their development is suppressed and latency period is increased as a result of a prolonged inhibition of a urine enzyme, beta-glucuronidase by treatment with poglucar. ...

    Title translation A new way of preventing urinary bladder tumors.
    Abstract An experimental study of urinary bladder tumor in rats has demonstrated that their development is suppressed and latency period is increased as a result of a prolonged inhibition of a urine enzyme, beta-glucuronidase by treatment with poglucar.
    MeSH term(s) Animals ; Anticarcinogenic Agents/therapeutic use ; Disease Models, Animal ; Dogs ; Glucuronidase/antagonists & inhibitors ; Rats ; Time Factors ; Urinary Bladder Neoplasms/enzymology ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/prevention & control
    Chemical Substances Anticarcinogenic Agents ; Glucuronidase (EC 3.2.1.31)
    Language Russian
    Publishing date 1996
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 955397-6
    ISSN 0507-3758
    ISSN 0507-3758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Sviaz' razvitiia raka tolstoĭ kishki s aktivnost'iu beta-gliukuronidazy.

    Vlasov, N N / Pliss, T B

    Voprosy onkologii

    1991  Volume 37, Issue 5, Page(s) 534–538

    Title translation Relationship between cancer of the large intestine and beta-glucuronidase activity.
    MeSH term(s) Animals ; Bacteria/enzymology ; Carcinogens ; Diet ; Glucuronidase/antagonists & inhibitors ; Glucuronidase/metabolism ; Humans ; Intestinal Neoplasms/etiology ; Intestine, Large ; Intestines/microbiology ; Rats
    Chemical Substances Carcinogens ; Glucuronidase (EC 3.2.1.31)
    Language Russian
    Publishing date 1991
    Publishing country Russia (Federation)
    Document type Journal Article ; Review
    ZDB-ID 955397-6
    ISSN 0507-3758
    ISSN 0507-3758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Novye vozmozhnosti profilaktiki raka kishechnika s ispol'zovaniem preparatov - ingibitorov beta-gliukuronidazy.

    Pliss, G B / Vlasov, N N / Anikin, I V

    Voprosy onkologii

    1998  Volume 44, Issue 1, Page(s) 68–73

    Abstract: Experiments involving the use of 1,2-dimethylhydrazine-induced colonic tumors in rats showed long-term treatment with a newly synthesized drug EDE-10g to inhibit an enzyme of enteric beta-glucuronidase, to suppress carcinogenesis and to prolong lifespan ... ...

    Title translation New means for the prophylaxis of colon cancer with the use of beta-glucuronidase inhibitors.
    Abstract Experiments involving the use of 1,2-dimethylhydrazine-induced colonic tumors in rats showed long-term treatment with a newly synthesized drug EDE-10g to inhibit an enzyme of enteric beta-glucuronidase, to suppress carcinogenesis and to prolong lifespan of animals.
    MeSH term(s) 1,2-Dimethylhydrazine ; Animals ; Anticarcinogenic Agents/pharmacology ; Colonic Neoplasms/chemically induced ; Colonic Neoplasms/enzymology ; Colonic Neoplasms/pathology ; Colonic Neoplasms/prevention & control ; Disease Models, Animal ; Glucuronidase/antagonists & inhibitors ; Male ; Rats ; Survival Analysis
    Chemical Substances Anticarcinogenic Agents ; Glucuronidase (EC 3.2.1.31) ; 1,2-Dimethylhydrazine (IX068S9745)
    Language Russian
    Publishing date 1998
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 955397-6
    ISSN 0507-3758
    ISSN 0507-3758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Rol' beta-gliukuronidazy v opukholevom protsesse i v profilaktike raka.

    Vlasov, N N / Pliss, G B

    Voprosy onkologii

    1990  Volume 36, Issue 9, Page(s) 1037–1044

    Title translation The role of beta-glucuronidase in the tumor process and cancer prevention.
    MeSH term(s) Animals ; Catalysis ; Cell Division/physiology ; Glucuronidase/physiology ; Gonadal Steroid Hormones/metabolism ; Humans ; Hydrolysis ; Neoplasms/enzymology ; Neoplasms/prevention & control ; Neoplasms, Experimental/enzymology ; Neoplasms, Experimental/prevention & control
    Chemical Substances Gonadal Steroid Hormones ; Glucuronidase (EC 3.2.1.31)
    Language Russian
    Publishing date 1990
    Publishing country Russia (Federation)
    Document type Journal Article ; Review
    ZDB-ID 955397-6
    ISSN 0507-3758
    ISSN 0507-3758
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  5. Article: Issledovanie kantserogennogo deĭstviia N,4-dinitrozo-N-metilaniliana.

    Vlasov, N N

    Voprosy onkologii

    1973  Volume 19, Issue 8, Page(s) 80–82

    Title translation Study of the carcinogenic action of N,4-dinitroso-N-methylaniline.
    MeSH term(s) Aniline Compounds/pharmacology ; Animals ; Carcinogens/pharmacology ; Female ; Injections, Subcutaneous ; Lung Neoplasms/chemically induced ; Lymphangioma/chemically induced ; Lymphatic Diseases/chemically induced ; Male ; Mediastinal Neoplasms/chemically induced ; Neoplasms, Experimental/chemically induced ; Neuroblastoma/chemically induced ; Nitroso Compounds/pharmacology ; Rats ; Rhabdomyosarcoma/chemically induced ; Thymus Neoplasms/chemically induced ; Time Factors
    Chemical Substances Aniline Compounds ; Carcinogens ; Nitroso Compounds
    Language Russian
    Publishing date 1973
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 955397-6
    ISSN 0507-3758
    ISSN 0507-3758
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  6. Article: Spektrofotometricheskoe opredelenie 20-metilkholantrena v razlichnykh sredakh.

    Vlasov, N N

    Voprosy onkologii

    1970  Volume 16, Issue 9, Page(s) 90–91

    Title translation Spectrophotometric determination of 20-methylcholanthrene in various media.
    MeSH term(s) Animals ; Carcinogens ; Methods ; Methylcholanthrene/analysis ; Methylcholanthrene/urine ; Rats ; Spectrophotometry ; Urinary Bladder/drug effects
    Chemical Substances Carcinogens ; Methylcholanthrene (56-49-5)
    Language Russian
    Publishing date 1970
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 955397-6
    ISSN 0507-3758
    ISSN 0507-3758
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  7. Article: O sinteze natrievoĭ soli beta-D-monogliukuronida fenolftaleina (substrata) dlia opredeleniia aktivnosti beta-gliukuronidazy.

    Vlasov, N N

    Laboratornoe delo

    1970  Volume 4, Page(s) 244–246

    Title translation Synthesis of the sodium slat of beta-D-monoglucuronide phenolphthalein (substrate) for the determination of beta-glucuronidase activity.
    MeSH term(s) Clinical Enzyme Tests ; Glucuronates/chemical synthesis ; Glucuronidase ; Phenolphthaleins/chemical synthesis
    Chemical Substances Glucuronates ; Phenolphthaleins ; Glucuronidase (EC 3.2.1.31)
    Language Russian
    Publishing date 1970
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 128774-6
    ISSN 0023-6748
    ISSN 0023-6748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Sostoianie pecheni pri razlichnykh formakh psevdotuberkuleza.

    Podlevskiĭ, A F / Vlasov, N N

    Klinicheskaia meditsina

    1986  Volume 64, Issue 11, Page(s) 91–95

    Title translation Status of the liver in different forms of pseudotuberculosis.
    MeSH term(s) Adolescent ; Adult ; Female ; Humans ; Liver/physiopathology ; Male ; Middle Aged ; Yersinia Infections/physiopathology ; Yersinia pseudotuberculosis Infections/physiopathology
    Language Russian
    Publishing date 1986-11
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 391034-9
    ISSN 0023-2149
    ISSN 0023-2149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 742: Show issues Location:
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  9. Article: Model' opukholi mochevogo puzyria krysy pri podkozhnom vvedenii N-butil-N-(4-gidroksibutil)-nitrozamina.

    Pliss, G B / Vlasov, N N / Iogannsen, M G / Frolov, A G

    Voprosy onkologii

    1998  Volume 44, Issue 4, Page(s) 432–435

    Abstract: A model of urinary bladder tumor was developed in the rat by subcutaneous injection of N-dibutyl-N-(4-hydroxybutyl) nitrosamine. A direct dose-tumor frequency correlation was established. Maximum effect (100%) was recorded with administration of 70 mg of ...

    Title translation A model of rat's urinary bladder tumor induced by subcutaneous injection of N-butyl-N-(4-hydroxybutyl)-nitrosamine.
    Abstract A model of urinary bladder tumor was developed in the rat by subcutaneous injection of N-dibutyl-N-(4-hydroxybutyl) nitrosamine. A direct dose-tumor frequency correlation was established. Maximum effect (100%) was recorded with administration of 70 mg of the carcinogenic agent twice a week, for 3 months. Among neoplasms induced were transitional-cell and in situ carcinoma, and multiple papilloma of the bladder. Carcinogenesis was found to involve a significant rise in the activity of urinary beta-gluco-uronidase which may be used as a diagnostic testing procedure.
    MeSH term(s) Animals ; Butylhydroxybutylnitrosamine/administration & dosage ; Butylhydroxybutylnitrosamine/toxicity ; Carcinogens/administration & dosage ; Carcinogens/toxicity ; Carcinoma in Situ/chemically induced ; Carcinoma, Transitional Cell/chemically induced ; Disease Models, Animal ; Glucuronidase/urine ; Papilloma/chemically induced ; Rats ; Urinary Bladder Neoplasms/chemically induced ; Urinary Bladder Neoplasms/enzymology ; Urinary Bladder Neoplasms/urine
    Chemical Substances Carcinogens ; Butylhydroxybutylnitrosamine (3817-11-6) ; Glucuronidase (EC 3.2.1.31)
    Language Russian
    Publishing date 1998
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 955397-6
    ISSN 0507-3758
    ISSN 0507-3758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Ispol'zovanie indutsirovannykh i spontannykh novoobrazovaniĭ zhivotnykh v éksperimental'noĭ terapii opukholeĭ.

    Anikin, I V / Pliss, G B / Vlasov, N N

    Voprosy onkologii

    1993  Volume 39, Issue 4-6, Page(s) 161–168

    Title translation The use of induced and spontaneous animal neoplasms in the experimental therapy of tumors.
    MeSH term(s) Adjuvants, Immunologic/therapeutic use ; Animals ; Antineoplastic Agents/therapeutic use ; Drug Screening Assays, Antitumor/veterinary ; Neoplasm Transplantation ; Neoplasms/drug therapy ; Neoplasms/veterinary ; Neoplasms, Experimental/drug therapy
    Chemical Substances Adjuvants, Immunologic ; Antineoplastic Agents
    Language Russian
    Publishing date 1993
    Publishing country Russia (Federation)
    Document type Journal Article ; Review
    ZDB-ID 955397-6
    ISSN 0507-3758
    ISSN 0507-3758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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