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  1. Book: Gray's atlas of anatomy

    Drake, Richard L. / Vogl, Wayne / Mitchell, Adam W. M.

    2020  

    Author's details Richard Drake, A. Wayne Vogl, Adam W. M. Mitchell
    Language English
    Size xvi, 628 Seiten, Illustrationen
    Edition Third edition
    Publisher Elsevier
    Publishing place New York
    Publishing country United States
    Document type Book
    Note Zugang zur Online-Ausgabe über Code
    HBZ-ID HT020473224
    ISBN 978-0-323-63639-1 ; 0-323-63639-X
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Gray's Atlas der Anatomie

    Drake, Richard L. / Vogl, Wayne / Mitchell, Adam W. M. / Tibbitts, Richard M. / Richardson, Paul E. / Bräuer, Lars

    2021  

    Title translation Gray´s Atlas of Anatomy
    Title variant Atlas der Anatomie
    Author's details Richard L. Drake, A. Wayne Vogl, Adam W.M. Mitchell, Richard M. Tibbitts, Paul E. Richardson ; deutsche Bearbeitung von: Prof. Dr. Lars Bräuer, Erlangen
    Keywords Anatomie
    Subject Mensch ; Tiere ; Tieranatomie ; Kunst der Zergliederung ; Zergliederungskunst
    Language German
    Size VIII, 560 Seiten, Illustrationen, 27.6 cm x 21.6 cm, 1788 g
    Edition 3. Auflage
    Publisher Elsevier
    Publishing place München
    Publishing country Germany
    Document type Book
    Old title Vorangegangen ist
    HBZ-ID HT021024587
    ISBN 978-3-437-44702-0 ; 3-437-44702-5 ; 9783437058523 ; 3437058525
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Gray's Atlas der Anatomie

    Drake, Richard L. / Vogl, Wayne / Mitchell, Adam W. M.

    2017  

    Title translation Gray´s Atlas of Anatomy
    Author's details Richard L. Drake, A. Wayne Vogl, Adam W.M. Mitchell ... [und andere]
    Keywords Anatomy ; 1. Studienabschnitt ; Physikum ; Vorklinik ; Anatomie
    Subject Mensch ; Tiere ; Tieranatomie ; Kunst der Zergliederung ; Zergliederungskunst
    Language German
    Size VIII, 558 Seiten, Illustrationen, Diagramme, 27.6 cm x 21.6 cm
    Edition 2. Auflage
    Publisher Elsevier
    Publishing place München
    Publishing country Germany
    Document type Book
    HBZ-ID HT019134103
    ISBN 978-3-437-44701-3 ; 3-437-44701-7
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Online ; E-Book: Gray's Atlas der Anatomie

    Drake, Richard L. / Bräuer, Lars / Vogl, Wayne / Mitchell, Adam W. M.

    2017  

    Title translation Gray´s atlas of anatomy
    Author's details Richard L. Drake, A. Wayne Vogl, Adam W.M. Mitchell ; Deutsche Bearbeitung von Lars Bräuer
    Keywords Human anatomy ; Atlases ; Electronic books ; Anatomy
    Language German
    Size 1 Online-Ressource (VIII, 558 Seiten), Illustrationen, Diagramme
    Edition 2. Auflage
    Publisher Elsevier, Urban & Fischer
    Publishing place München
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020545270
    ISBN 978-3-437-18059-0 ; 9783437447013 ; 3-437-18059-2 ; 3437447017
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book: Gray's anatomy for students

    Drake, Richard L. / Vogl, Wayne / Mitchell, Adam W. M. / Gray, Henry

    (Student consult)

    2015  

    Title variant Anatomy for students
    Author's details [Richard L. Drake ; A. Wayne Vogl ; Adam W. M. Mitchell]
    Series title Student consult
    Keywords Anatomy ; Anatomie
    Subject Mensch ; Tiere ; Tieranatomie ; Kunst der Zergliederung ; Zergliederungskunst
    Language English
    Size XXV, 1161 S. : zahlr. Ill., graph. Darst., 28cm
    Edition 3. ed.
    Publisher Churchill Livingstone Elsevier
    Publishing place Philadelphia, Pa. u.a.
    Publishing country United States
    Document type Book
    Accompanying material Zugang zu zusätzlichem Internetmaterial über Code
    HBZ-ID HT018247109
    ISBN 978-0-7020-5131-9 ; 978-0-7020-5132-6 ; 0-7020-5131-4 ; 0-7020-5132-2
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: A "Welcoming" Introduction to a Canadian Northwest Coast Thematic Papers Issue.

    Vogl, Wayne

    Anatomical record (Hoboken, N.J. : 2007)

    2017  Volume 300, Issue 11, Page(s) 1930–1934

    Abstract: In this commentary, I provide an introduction to and the context for the four articles in the thematic series published to celebrate the Editorial Board Meeting of the Anatomical Record in Vancouver, British Columbia, Canada in July of 2017. The articles ...

    Abstract In this commentary, I provide an introduction to and the context for the four articles in the thematic series published to celebrate the Editorial Board Meeting of the Anatomical Record in Vancouver, British Columbia, Canada in July of 2017. The articles describe various aspects of whale anatomy and the potential for a new generation of digital tags to provide information on functional anatomy of free swimming animals in the wild. The whales described are all native to the northwest coast of North America, as well as being found elsewhere, and the authors are related in some way to the University of British Columbia in Vancouver. Anat Rec, 300:1930-1934, 2017. © 2017 Wiley Periodicals, Inc.
    Language English
    Publishing date 2017-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2269667-2
    ISSN 1932-8494 ; 1932-8486
    ISSN (online) 1932-8494
    ISSN 1932-8486
    DOI 10.1002/ar.23675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: ORP9 knockdown delays the maturation of junction-related endocytic structures in the testis and leads to impaired sperm release†.

    Adams, Arlo / Vogl, Wayne

    Biology of reproduction

    2020  Volume 103, Issue 6, Page(s) 1314–1323

    Abstract: The release of late spermatids from the seminiferous epithelium requires the internalization of intercellular junctions by Sertoli cell specific structures called "tubulobulbar complexes" (TBCs). These large, endocytic devices likely evolved from classic ...

    Abstract The release of late spermatids from the seminiferous epithelium requires the internalization of intercellular junctions by Sertoli cell specific structures called "tubulobulbar complexes" (TBCs). These large, endocytic devices likely evolved from classic clathrin-mediated-endocytosis (CME) machinery, but have several important morphological differences to CME vesicles. Most notable among these differences is that extensive endoplasmic reticulum (ER) membrane contact sites (MCSs) occur with TBCs and not with clathrin-coated pits. One of the well-established functions of ER MCSs is lipid exchange. Previously, we have established that the ORP9 lipid exchange protein is localized to the TBC-ER MCS; however, the function of ORP9 and lipid exchange at the sites is not known. Here we use an in vivo knockdown approach to probe function. The testes of Sprague-Dawley rats were injected with ORP9 targeted siRNA or non-targeted reagents, and the tissues examined by bright field, super-resolution stimulated emission depletion, and electron microscopy. The knockdown of ORP9 was achieved and maintained with daily injections of siRNA for 2-3 day intervals. Compared to controls, sections from ORP9 siRNA-injected testes had longer TBC tubes and fewer fused TBC bulbs. Late spermatids were also abnormally retained in the epithelium of knockdown tissue. These results suggest that ORP9 is necessary for normal TBC bulb vesiculation and fusion, most likely by changing the plasma membrane lipid profile of the TBC. These data also further support the conclusion that TBCs are part of the normal mechanism of sperm release.
    MeSH term(s) Animals ; Antibodies ; Gene Knockdown Techniques ; Male ; Phosphatidylinositol 4,5-Diphosphate/metabolism ; RNA, Small Interfering ; Rats ; Rats, Sprague-Dawley ; Receptors, Steroid/genetics ; Receptors, Steroid/metabolism ; Sexual Maturation ; Spermatogenesis ; Testis/growth & development
    Chemical Substances Antibodies ; Phosphatidylinositol 4,5-Diphosphate ; RNA, Small Interfering ; Receptors, Steroid
    Language English
    Publishing date 2020-09-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1118-6
    ISSN 1529-7268 ; 0006-3363
    ISSN (online) 1529-7268
    ISSN 0006-3363
    DOI 10.1093/biolre/ioaa159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Knockdown of IP3R1 disrupts tubulobulbar complex-ectoplasmic reticulum contact sites and the morphology of apical processes encapsulating late spermatids†.

    Adams, Arlo / Vogl, Wayne

    Biology of reproduction

    2020  Volume 103, Issue 3, Page(s) 669–680

    Abstract: Tubulobulbar complexes (TBCs) internalize intercellular junctions during sperm release. One of the characteristic features of TBCs is that they form "bulbs" or swollen regions that have well-defined membrane contact sites (MCS) with adjacent cisternae of ...

    Abstract Tubulobulbar complexes (TBCs) internalize intercellular junctions during sperm release. One of the characteristic features of TBCs is that they form "bulbs" or swollen regions that have well-defined membrane contact sites (MCS) with adjacent cisternae of endoplasmic reticulum. Previously, we have localized the IP3R calcium channel to the TBC bulb-ER contacts and have hypothesized that fluctuations in local calcium levels may facilitate the maturation of TBC bulbs into putative endosomes, or alter local actin networks that cuff adjacent tubular regions of the TBCs. To test this, we injected the testes of Sprague Dawley rats with small interfering RNAs (siRNAs) against IP3R1 and processed the tissues for either western blot, immunofluorescence, or electron microscopy. When compared to control testes injected with nontargeting siRNAs, Sertoli cells in knocked-down testes showed significant morphological alterations to the actin networks including a loss of TBC actin and the appearance of ectopic para-crystalline actin bundles in Sertoli cell stalks. There also was a change in the abundance and distribution of TBC-ER contact sites and large internalized endosomes. This disruption of TBCs resulted in delay of the withdrawal of apical processes away from spermatids and in spermiation. Together, these findings are consistent with the hypothesis that calcium exchange at TBC-ER contacts is involved both in regulating actin dynamics at TBCs and in the maturing of TBC bulbs into endosomes. The results are also consistent with the hypothesis that TBCs are part of the sperm release mechanism.
    MeSH term(s) Actins/biosynthesis ; Actins/genetics ; Animals ; Calcium Signaling/genetics ; Cell Communication ; Gene Knockdown Techniques ; Injections ; Inositol 1,4,5-Trisphosphate Receptors/genetics ; Male ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/pharmacology ; Rats ; Rats, Sprague-Dawley ; Seminiferous Epithelium ; Sertoli Cells ; Spermatids/physiology ; Spermatids/ultrastructure ; Spermatogenesis/genetics ; Testis/cytology ; Testis/metabolism ; Testis/ultrastructure
    Chemical Substances Actins ; Inositol 1,4,5-Trisphosphate Receptors ; Itpr1 protein, rat ; RNA, Small Interfering
    Language English
    Publishing date 2020-05-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1118-6
    ISSN 1529-7268 ; 0006-3363
    ISSN (online) 1529-7268
    ISSN 0006-3363
    DOI 10.1093/biolre/ioaa074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Gray's anatomy for students

    Drake, Richard L. / Vogl, Wayne / Mitchell, Adam W. M. / Gray, Henry

    (Student consult)

    2010  

    Title variant Anatomy for students
    Author's details Richard L. Drake ; A. Wayne Vogl ; Adam W. M. Mitchell
    Series title Student consult
    Keywords Anatomy
    Language English
    Size XXV, 1103 S. : zahlr. Ill., graph. Darst., 28cm
    Edition 2. ed.
    Publisher Churchill Livingstone Elsevier
    Publishing place Philadelphia, Pa. u.a.
    Publishing country United States
    Document type Book
    Accompanying material Zugang zu zusätzlichem Internetmaterial über Code
    HBZ-ID HT016580372
    ISBN 978-0-443-06952-9 ; 978-0-80892-406-7 ; 0-443-06952-2 ; 0-80892-406-0
    Database Catalogue ZB MED Medicine, Health

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  10. Book: Gray's Anatomie für Studenten

    Drake, Richard L. / Vogl, Wayne / Mitchell, Adam W. M. / Gray, Henry

    2007  

    Title translation Gray's anatomy for students
    Author's details Richard L. Drake ; Wayne Vogl ; Adam W. M. Mitchell
    Keywords Anatomy ; Anatomie
    Subject Mensch ; Tiere ; Tieranatomie ; Kunst der Zergliederung ; Zergliederungskunst
    Language German
    Size XXXI, 1092 S. : zahlr. Ill.
    Edition 1. Aufl.
    Publisher Elsevier, Urban & Fischer
    Publishing place München u.a.
    Publishing country Germany
    Document type Book
    Note Aus dem Engl. übers.
    HBZ-ID HT015208517
    ISBN 978-3-437-41231-8 ; 3-437-41231-0
    Database Catalogue ZB MED Medicine, Health

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