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  1. Article ; Online: Novel nanotech antioxidant cocktail prevents medical diagnostic procedures ionizing radiation effects.

    Gorenberg, Miguel / Agbarya, Abed / Groshar, David / Volovik, Ilya / Avitan, Ofir / Sukhotnik, Igor

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 5315

    Abstract: Ionizing radiation (IR) exposure results in oxidative damage causing cytotoxic and genotoxic effects. Double-strand breaks (DSBs) are considered the most significant DNA lesions induced by ionizing radiation. The present study evaluates the radio ... ...

    Abstract Ionizing radiation (IR) exposure results in oxidative damage causing cytotoxic and genotoxic effects. Double-strand breaks (DSBs) are considered the most significant DNA lesions induced by ionizing radiation. The present study evaluates the radio protective effect of a novel antioxidant cocktail through quantification of DSB in peripheral blood lymphocytes (PBL) in vivo. The study included 16 consecutive patients who were divided into 2 groups, 6 patients received the novel antioxidant cocktail and 10 control patients. Blood samples were drawn from the patients undergoing bone scan, before the injection of the
    MeSH term(s) Adult ; Aged ; Antioxidants/administration & dosage ; DNA Breaks, Double-Stranded/drug effects ; Female ; Humans ; Lymphocytes/drug effects ; Lymphocytes/pathology ; Male ; Middle Aged ; Neoplasms/diagnostic imaging ; Neoplasms/radiotherapy ; Radiation Injuries/drug therapy ; Young Adult
    Chemical Substances Antioxidants
    Language English
    Publishing date 2021-03-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-84596-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [MANAGING LUNG CANCER PATIENTS' CARE DURING THE COVID-19 PANDEMIC].

    Agbarya, Abed / Khoury, Rasha / Nasser, Nicola J / Lazri, Sahar / Volovik, Ilya / Gorenberg, Miguel

    Harefuah

    2020  Volume 159, Issue 7, Page(s) 470–474

    Abstract: Background: Lung cancer patients who contract the new coronavirus, appear to have a greater risk for severe COVID-19 illness along with early deterioration and death. However, the prognosis may depend on the cancer stage and the type of treatment ... ...

    Abstract Background: Lung cancer patients who contract the new coronavirus, appear to have a greater risk for severe COVID-19 illness along with early deterioration and death. However, the prognosis may depend on the cancer stage and the type of treatment administered.
    Objectives: Establishing updated treatments and care management regulations for lung cancer patients during the COVID-19 pandemic, based on worldwide clinical experience.
    Methods: This article reviews the main recommendations described by the American and European Oncology Societies managing lung cancer patients infected by COVID-19.
    Results: In the current pandemic setting, attempts should be made to avoid jeopardizing the prognosis of lung cancer patients, by maintaining current guidelines in oncology practice. In cases of patients with active infection, the recommendation is to hold treatment until recovery. For other patients, due to the aggressive nature of lung cancer, the guidelines suggest not to delay curative treatments in non-metastatic disease and provide palliative treatment in shortened protocols.
    Conclusions: The present summary of guideline recommendations provides different management strategies for patients with lung cancer. These care approaches attempt to solve new challenges raised by the COVID-19 pandemic. Each specific case must be considered individually.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Europe ; Humans ; Lung Neoplasms/therapy ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Societies, Medical ; United States
    Keywords covid19
    Language Hebrew
    Publishing date 2020-09-02
    Publishing country Israel
    Document type Journal Article
    ZDB-ID 953872-0
    ISSN 0017-7768
    ISSN 0017-7768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 291: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  3. Article: [managing Lung Cancer Patients' Care during the Covid-19 Pandemic]

    Agbarya, Abed / Khoury, Rasha / Nasser, Nicola J. / Lazri, Sahar / Volovik, Ilya / Gorenberg, Miguel

    Harefuah

    Abstract: BACKGROUND: Lung cancer patients who contract the new coronavirus, appear to have a greater risk for severe COVID-19 illness along with early deterioration and death However, the prognosis may depend on the cancer stage and the type of treatment ... ...

    Abstract BACKGROUND: Lung cancer patients who contract the new coronavirus, appear to have a greater risk for severe COVID-19 illness along with early deterioration and death However, the prognosis may depend on the cancer stage and the type of treatment administered OBJECTIVES: Establishing updated treatments and care management regulations for lung cancer patients during the COVID-19 pandemic, based on worldwide clinical experience METHODS: This article reviews the main recommendations described by the American and European Oncology Societies managing lung cancer patients infected by COVID-19 RESULTS: In the current pandemic setting, attempts should be made to avoid jeopardizing the prognosis of lung cancer patients, by maintaining current guidelines in oncology practice In cases of patients with active infection, the recommendation is to hold treatment until recovery For other patients, due to the aggressive nature of lung cancer, the guidelines suggest not to delay curative treatments in non-metastatic disease and provide palliative treatment in shortened protocols CONCLUSIONS: The present summary of guideline recommendations provides different management strategies for patients with lung cancer These care approaches attempt to solve new challenges raised by the COVID-19 pandemic Each specific case must be considered individually
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #688652
    Database COVID19

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