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  1. Article: Effects of Exercise With and Without Energy Replacement on Substrate Utilization in the Fasting State

    Kang, Jie / Hasan, Saif B / Ellis, Nicole A / Vought, Ira T / Ratamess, Nicholas A / Bush, Jill A / Faigenbaum, Avery D

    Journal of the American College of Nutrition. 2020 Jan. 2, v. 39, no. 1

    2020  

    Abstract: Objective: The present study aimed to examine the interactive effect of exercise and energy balance on energy expenditure and substrate utilization. Method: Seven men and 7 women underwent three 2-day experimental protocols in a random order. Each ... ...

    Abstract Objective: The present study aimed to examine the interactive effect of exercise and energy balance on energy expenditure and substrate utilization. Method: Seven men and 7 women underwent three 2-day experimental protocols in a random order. Each protocol consisted of no exercise (NE), exercise only (EO), or exercise with a matched energy replacement (ER) on day 1 followed by metabolic testing that occurred after a 12-hour overnight fasting on day 2. Both EO and ER involved treadmill running at 60% maximal oxygen uptake (VO2max) that induced an energy expenditure of ∼ 500 kcal. The replacement meal used in ER contained ∼ 500 kcal made up of 45% carbohydrate, 30% fat, and 25% protein. During metabolic testing, oxygen uptake (VO2), heart rate (HR), respiratory exchange ratio (RER), and rates of carbohydrate (COX) and fat oxidation (FOX) were determined in three successive 15-minute periods including rest and exercise at 50% and 70% VO2max. Results: No differences in VO2 and HR were found at rest among NE, EO, and ER. However, RER was lower in EO than NE (0.840 ± 0.014 vs 0.889 ± 0.012, p < 0.05), COX (g·min−1) was lower in ER than NE (0.144 ± 0.016 vs 0.197 ± 0.019, p < 0.05), and FOX (g·min−1) was higher in EO or ER than NE (0.054 ± 0.010 or 0.057 ± 0.009 vs 0.034 ± 0.007, p < 0.05). No treatment effects were observed for all variables at either intensity. Conclusions: This study demonstrates that an exercise of moderate intensity can increase resting fat oxidation even when the exercise-induced energy expenditure is balanced by energy intake. This finding suggests that muscle action is vital in augmenting fat utilization.
    Keywords carbohydrate content ; carbohydrates ; energy expenditure ; energy intake ; exercise ; fasting ; heart rate ; lipid content ; lipid metabolism ; men ; muscles ; oxygen ; protein content ; women
    Language English
    Dates of publication 2020-0102
    Size p. 39-46.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 603204-7
    ISSN 1541-1087 ; 0731-5724
    ISSN (online) 1541-1087
    ISSN 0731-5724
    DOI 10.1080/07315724.2019.1605549
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Effects of Exercise With and Without Energy Replacement on Substrate Utilization in the Fasting State.

    Kang, Jie / Hasan, Saif B / Ellis, Nicole A / Vought, Ira T / Ratamess, Nicholas A / Bush, Jill A / Faigenbaum, Avery D

    Journal of the American College of Nutrition

    2019  Volume 39, Issue 1, Page(s) 39–46

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adult ; Carbohydrate Metabolism/physiology ; Cross-Over Studies ; Energy Intake/physiology ; Energy Metabolism/physiology ; Exercise/physiology ; Fasting/metabolism ; Female ; Heart Rate/physiology ; Humans ; Lipid Metabolism/physiology ; Male ; Meals/physiology ; Oxidation-Reduction ; Oxygen Consumption ; Running/physiology
    Language English
    Publishing date 2019-04-23
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 603204-7
    ISSN 1541-1087 ; 0731-5724
    ISSN (online) 1541-1087
    ISSN 0731-5724
    DOI 10.1080/07315724.2019.1605549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Acute Cardiorespiratory and Metabolic Effects of a Sandbag Resistance Exercise Protocol.

    Ratamess, Nicholas A / Kang, Jie / Kuper, Jeremy D / OʼGrady, Elizabeth A / Ellis, Nicole L / Vought, Ira T / Culleton, Emma / Bush, Jill A / Faigenbaum, Avery D

    Journal of strength and conditioning research

    2018  Volume 32, Issue 6, Page(s) 1491–1502

    Abstract: Ratamess, NA, Kang, J, Kuper, JD, O'Grady, EA, Ellis, NL, Vought, IT, Culleton, E, Bush, JA, and Faigenbaum, AD. Acute cardiorespiratory and metabolic effects of a sandbag resistance exercise protocol. J Strength Cond Res 32(6): 1491-1502, 2018-The ... ...

    Abstract Ratamess, NA, Kang, J, Kuper, JD, O'Grady, EA, Ellis, NL, Vought, IT, Culleton, E, Bush, JA, and Faigenbaum, AD. Acute cardiorespiratory and metabolic effects of a sandbag resistance exercise protocol. J Strength Cond Res 32(6): 1491-1502, 2018-The purpose of this study was to examine the acute cardiorespiratory and metabolic effects of a sandbag (SB) resistance exercise protocol and compare the responses to time-matched treadmill running protocols. Eight healthy, resistance-trained men (21.1 ± 1.0 years; 86.1 ± 7.8 kg) completed 4 protocols of equal duration in random sequence: (a) SB, (b) treadmill running at 60% of V[Combining Dot Above]O2 reserve (60V[Combining Dot Above]O2R), (c) treadmill running at 80% of V[Combining Dot Above]O2 reserve (80V[Combining Dot Above]O2R), and (d) a control protocol. The SB protocol was 16 minutes in duration and consisted of 3 circuits of 8 multiple-joint exercises (with 11-, 20-, or 48-kg SBs) performed for as many repetitions as possible for 20 seconds followed by a 10-second rest interval before beginning the next exercise. Two minutes of rest was allowed between circuits. Breath-by-breath oxygen consumption (V[Combining Dot Above]O2) and heart rate (HR) were recorded throughout each protocol and for 30 minutes postexercise (PE) and blood lactate was determined before and immediately after each protocol. Blood lactate was significantly higher after SB compared with 60V[Combining Dot Above]O2R and 80V[Combining Dot Above]O2R. Mean and peak HR in SB was significantly higher than 60V[Combining Dot Above]O2R but not different from 80V[Combining Dot Above]O2R. Mean V[Combining Dot Above]O2 and energy expenditure (EE) in SB was significantly lower than 60V[Combining Dot Above]O2R and 80V[Combining Dot Above]O2R during each protocol but significantly higher after SB compared with 60V[Combining Dot Above]O2R and 80V[Combining Dot Above]O2R PE. Compared with 60V[Combining Dot Above]O2R and 80V[Combining Dot Above]O2R, respiratory exchange ratio was significantly higher during SB and through 5 minutes PE, but was significantly lower at 25-30 minutes PE after SB. Sandbag, as performed in this study, provides a superior metabolic stimulus to treadmill running during the PE period; however, the SB results demonstrate inferior EE compared with running at 60V[Combining Dot Above]O2R and 80V[Combining Dot Above]O2R.
    MeSH term(s) Adolescent ; Energy Metabolism ; Exercise Test ; Heart Rate ; Humans ; Lactic Acid/blood ; Male ; Oxygen Consumption ; Random Allocation ; Resistance Training/methods ; Running/physiology ; Young Adult
    Chemical Substances Lactic Acid (33X04XA5AT)
    Language English
    Publishing date 2018-01-19
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 1156349-7
    ISSN 1533-4287 ; 1064-8011
    ISSN (online) 1533-4287
    ISSN 1064-8011
    DOI 10.1519/JSC.0000000000002415
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Acute hematological and mood perception effects of bitter orange extract (p-synephrine) consumed alone and in combination with caffeine: A placebo-controlled, double-blind study.

    Bush, Jill A / Ratamess, Nicholas A / Stohs, Sidney J / Ellis, Nicole L / Vought, Ira T / O'Grady, Elizabeth A / Kuper, Jeremy D / Kang, Jie / Faigenbaum, Avery D

    Phytotherapy research : PTR

    2018  Volume 32, Issue 8, Page(s) 1593–1607

    Abstract: The purpose of this study was to examine acute hematological and mood perception responses to supplementation with p-synephrine alone and in combination with caffeine during quiet sitting. Sixteen subjects visited the laboratory on 6 occasions and were ... ...

    Abstract The purpose of this study was to examine acute hematological and mood perception responses to supplementation with p-synephrine alone and in combination with caffeine during quiet sitting. Sixteen subjects visited the laboratory on 6 occasions and were given (in randomized double-blind manner) 103-mg p-synephrine (S), 233-mg caffeine + 104-mg p-synephrine, 240-mg caffeine, 337-mg caffeine + 46-mg p-synephrine, 325-mg caffeine, or a placebo (PL). The subjects sat quietly for 3 hr while completing mood state questionnaires every 30 min. Venous blood samples were collected at baseline (pre) and 3 hr (post) to determine immune, lipid, and chemistry panels. Compared with PL, no significant supplement differences were observed during the S trial with the exception of differential time effects seen in hematocrit (decrease in PL, no change in S), triglycerides and very low-density lipoproteins (no changes in PL, significant decreases in S), and iron (no change in PL, significant elevation in S). Supplements containing caffeine showed increased feelings of attention, excitement, energy, and vigor. These data indicate that consumption of 103-mg p-synephrine does not negatively impact acute blood parameters, does not augment the effects of caffeine, or produce stimulant-like perceptual mood effects.
    MeSH term(s) Affect/drug effects ; Blood Chemical Analysis ; Caffeine/pharmacology ; Dietary Supplements ; Double-Blind Method ; Female ; Hematocrit ; Humans ; Iron/blood ; Lipoproteins, VLDL/blood ; Male ; Plant Extracts/pharmacology ; Synephrine/pharmacology ; Triglycerides/blood ; Young Adult
    Chemical Substances Lipoproteins, VLDL ; Plant Extracts ; Triglycerides ; Caffeine (3G6A5W338E) ; Iron (E1UOL152H7) ; Synephrine (PEG5DP7434)
    Language English
    Publishing date 2018-04-19
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.6090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Acute cardiovascular effects of bitter orange extract (p-synephrine) consumed alone and in combination with caffeine in human subjects: A placebo-controlled, double-blind study.

    Ratamess, Nicholas A / Bush, Jill A / Stohs, Sidney J / Ellis, Nicole L / Vought, Ira T / O'Grady, Elizabeth A / Kuper, Jeremy D / Hasan, Saif B / Kang, Jie / Faigenbaum, Avery D

    Phytotherapy research : PTR

    2017  

    Abstract: The purpose was to examine cardiovascular responses to supplementation with p-synephrine alone and in combination with caffeine during quiet sitting. Sixteen subjects were given (in double-blind manner) either 103 mg of p-synephrine (S), 233 mg of ... ...

    Abstract The purpose was to examine cardiovascular responses to supplementation with p-synephrine alone and in combination with caffeine during quiet sitting. Sixteen subjects were given (in double-blind manner) either 103 mg of p-synephrine (S), 233 mg of caffeine +104 mg of p-synephrine (LC + S), 240 mg of caffeine (LC), 337 mg of caffeine +46 mg of p-synephrine (HC + S), 325 mg of caffeine (HC), or a placebo. The subjects sat quietly for 3 hr while heart rate (HR) and blood pressure were measured. Only HC + S and HC significantly increased mean systolic blood pressure (SBP) during the second hour and tended to increase mean SBP during the third hour. Mean diastolic blood pressure in S was significantly lower than the other trials during the first and second hours, and mean arterial pressure was significantly lower in S compared to the LC, LC + S, HC, and HC + S trials. No differences were observed in HR. Consumption of p-synephrine may acutely reduce diastolic blood pressure and mean arterial pressure and not affect SBP or HR during quiet sitting. The addition of p-synephrine to caffeine did not augment SBP or HR indicating that consumption of up to 104 mg of p-synephrine does not induce cardiovascular stress during quiet sitting.
    Language English
    Publishing date 2017-10-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.5953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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