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Article ; Online: Antegrade cholecystectomy before ligating the elements. A technique that reduces complications.

Tartaglia, Nicola / Petruzzelli, Fabio / Vovola, Fernanda / Fersini, Alberto / Ambrosi, Antonio

2019 Volume 90, Page(s) 162–164

Abstract: Background: In open surgery, the most common approach is Retrograde approach ("fundus first"), while is less frequent in laparoscopic cholecystectomy. Antegrade access, is obtained by putting in traction the infundibulum and reaching up to the fundus ... ...

Abstract	Background: In open surgery, the most common approach is Retrograde approach ("fundus first"), while is less frequent in laparoscopic cholecystectomy. Antegrade access, is obtained by putting in traction the infundibulum and reaching up to the fundus right before clipping the cystic. Our study analyzes a number of surgical procedures performed by surgeons with long experience in laparoscopy. Methods: From 2002 to 2017, 2020 laparoscopic cholecystectomies were performed at our Institution. The operative technique used since 2002 is the following: incision of the visceral peritoneum from the infundibulum away from Calot's triangle along the gallbladder bed up to the fundus and then to the infundibulum. Results: No bile duct injuries happened. Average operative time was 38 min. 30 conversions to an open procedure (1.5%) occurred, in patients with cholecystitis and cirrhosis Postoperative stay was mean 2 days with no delayed complications on follow up. Conclusions: Gallbladder antegrade dissection for laparoscopic cholecystectomy may be an easier approach and may reduce the time of surgery. So it may be used as the standard procedure and not only be used for complicated cholecystectomies. Key words: Difficult cholecystectomy, Laparoscopy, Antegrade dissection, Cholecystectomy, Cholecystitis, Fundus first.
MeSH term(s)	Cholecystectomy, Laparoscopic/methods ; Cholecystitis/surgery ; Humans ; Postoperative Complications/prevention & control
Language	English
Publishing date	2019-06-10
Publishing country	Italy
Document type	Journal Article
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: How emergency surgery has changed during the COVID-19 pandemic: A cohort study.

Tartaglia, Nicola / Pavone, Giovanna / Lizzi, Vincenzo / Vovola, Fernanda / Tricarico, Fausto / Pacilli, Mario / Ambrosi, Antonio

Annals of medicine and surgery (2012)

2020 Volume 60, Page(s) 686–689

Abstract: Introduction: Various surgical societies constantly update their recommendations in order to adapt surgical activity on current Pandemic conditions. The aim of this study is to analyze how hospitalizations and emergency operations have changed in our ... ...

Abstract	Introduction: Various surgical societies constantly update their recommendations in order to adapt surgical activity on current Pandemic conditions. The aim of this study is to analyze how hospitalizations and emergency operations have changed in our Department of Medical and Surgical Sciences in the Hospital of Foggia during covid-19 pandemic. Methods: Our cohort-study was conducted by analyzing two groups of patients admitted to the Department of Medical and Surgical Sciences of the Hospital of Foggia: those admitted during the no-covid period from March 09th, 2019 to May 09th, 2019 and those during the covid period from March 09th, 2020 to May 09th, 2020. Results: A total of 750 patients admitted during the no-covid period of 2019 and 171 during the covid period of 2020, of these 222 were emergency admission during 2019 and 97 during 2020, 528 were elective admission during 2019 and 74 during 2020. Of the emergency admissions (222 during 2019 and 97 during 2020), 91 were operated during the no covid period in 2019 and 52 during the covid period in 2020. The mean Mannheim Peritonitis Index Score, that is a scoring system used in peritonitis which is simple and cost-effective, were 15.6 during the no covid period of 2019 and 22.2 during the covid period of 2020. We observed 29 post-operative complications during 2019 and 26 during 2020. Conclusions: Contraction of admissions for urgent and emergent conditions in the first period of lockdown has been followed from some positive effects as well as aggravating consequences.
Language	English
Publishing date	2020-12-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2745440-X
ISSN	2049-0801
ISSN	2049-0801
DOI	10.1016/j.amsu.2020.12.001
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Article ; Online: Bilateral central neck dissection in the treatment of early unifocal papillary thyroid carcinomas with poor risk factors A mono-institutional experience.

Tartaglia, Nicola / Di Lascia, Alessandra / Vovola, Fernanda / Cianci, Pasquale / Fersini, Alberto / Pacilli, Mario / Pavone, Giovanna / Ambrosi, Antonio

Annali italiani di chirurgia

2020 Volume 91, Page(s) 161–165

Abstract: Introduction: Papillary thyroid carcinoma is the most common type of thyroid cancer worldwide. While total thyroidectomy is widely considered the standard surgical approach for papillary thyroid carcinomas, the role of central lymphadenectomy in early ... ...

Abstract	Introduction: Papillary thyroid carcinoma is the most common type of thyroid cancer worldwide. While total thyroidectomy is widely considered the standard surgical approach for papillary thyroid carcinomas, the role of central lymphadenectomy in early stage poor-risk papillary thyroid tumors is still a matter of debate. This study was designed to assess surgical complications and local disease control rates in patients affected by poor-risk early stage papillary thyroid carcinomas. Methods: We retrospectively analyze three groups of patients affected by poor-risk early stage papillary thyroid carcinomas treated with three alternative surgical strategies: I) routine total thyroidectomy; II) total thyroidectomy and routine central lymphadenectomy; III) total thyroidectomy and central lymphadenectomy upon positive intraoperative histological evaluation of lymph node involvement. Results: Data from patients treated with routine total thyroidectomy showed 32% of persistence of disease in the central compartment with concurrent positivity in laterocervical compartment in 25% of these cases. By contrast, patients receiving total thyroidectomy and routine central lymphadenectomy showed the involvement of central compartment in 40% of cases, while the remaining 60% of patients were free from lymph node metastases. Finally, patients undergoing total thyroidectomy and central lymphadenectomy upon positive intraoperative lymph node biopsy exhibited lack of persistence of lymph node involvement in central compartment after surgery. Of note, postsurgical complications were lower in patients undergoing conservative surgical approaches. Conclusions: These data suggest that central lymphadenectomy, performed only in case of positive intraoperative lymph node biopsy, ensures reduced incidence of postoperative complications and optimal loco-regional disease control. Key words: Bilateral central neck dissection, Intraoperative lymph node biopsy, Papillary thyroid carcinoma, Poor risk factors.
MeSH term(s)	Carcinoma, Papillary/surgery ; Humans ; Lymph Node Excision ; Neck Dissection ; Neoplasm Recurrence, Local/surgery ; Retrospective Studies ; Risk Factors ; Thyroid Cancer, Papillary/surgery ; Thyroid Neoplasms/surgery ; Thyroidectomy
Language	English
Publishing date	2020-03-08
Publishing country	Italy
Document type	Journal Article
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Right hemicolectomy: laparoscopic versus robotic approach.

Di Lascia, Alessandra / Tartaglia, Nicola / Petruzzelli, Fabio / Pacilli, Mario / Maddalena, Francesca / Fersini, Alberto / Pavone, Giovanna / Vovola, Fernanda / Ambrosi, Antonio

Annali italiani di chirurgia

2020 Volume 91, Page(s) 478–485

Abstract: Background: Minimally invasive surgery for colorectal cancer has been demonstrated to have the same oncological results as open surgery, with better clinical outcomes. Robotic surgery is an evolution of minimally invasive technique. This study aims to ... ...

Abstract	Background: Minimally invasive surgery for colorectal cancer has been demonstrated to have the same oncological results as open surgery, with better clinical outcomes. Robotic surgery is an evolution of minimally invasive technique. This study aims to evaluate surgical and oncological short-term outcomes of robotic right colon resection in comparison with the laparoscopic approach. Methods: Between January 2014 and May 2017, fifteen laparoscopic right hemicolectomies were compared to seven robotic ones. The primary data points included operation time, length of hospital stay, extraction site incision length, complications, and conversions. When malignancy was the indication for surgery, additional data points have been added. Results: The study showed no difference in parameters between the two groups, but estimated blood loss was significantly smaller for Robotic arm. We found a prolonged total operative room time in the robotic arm, while the surgical time is similar in two groups. The data collected about specimen length and number of lymph nodes suggest that robotic procedure is oncologically similar to laparoscopic one. Conclusions: Robotic approach allows performance of adequate dissection of the right colon with radical lymphadenectomy as in laparoscopic surgery, confirming the safety and oncological efficacy of this technique, with acceptable results and short-term outcomes. Key words: Da Vinci surgery, XI, Laparoscopic colorectal surgery, Right hemicolectomy, Robot.
MeSH term(s)	Colectomy/methods ; Colorectal Neoplasms/surgery ; Humans ; Laparoscopy ; Operative Time ; Robotic Surgical Procedures ; Treatment Outcome
Language	English
Publishing date	2020-06-10
Publishing country	Italy
Document type	Comparative Study ; Evaluation Study ; Journal Article
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Robotic voluminous paraesophageal hernia repair: a case report and review of the literature.

Tartaglia, Nicola / Pavone, Giovanna / Di Lascia, Alessandra / Vovola, Fernanda / Maddalena, Francesca / Fersini, Alberto / Pacilli, Mario / Ambrosi, Antonio

Journal of medical case reports

2020 Volume 14, Issue 1, Page(s) 25

Abstract: Background: The treatment for sliding esophageal hernia with mild gastroesophageal reflux is usually conservative, but surgical treatment is recommended for refractory sliding esophageal hernia, paraesophageal hernia liable to prolapse, or ... ...

Abstract	Background: The treatment for sliding esophageal hernia with mild gastroesophageal reflux is usually conservative, but surgical treatment is recommended for refractory sliding esophageal hernia, paraesophageal hernia liable to prolapse, or paraesophageal hernia with ulceration and/or stenosis. Robotic surgery overcomes laparoscopic pitfalls by providing steady-state three-dimensional visualization, augmented dexterity with endo-wrist movements, and superior ergonomics for the surgeon. Case presentation: To investigate robotic paraesophageal hernia repair, a literature search was conducted using PubMed with the following key words: mini invasive surgery, robotic surgery, hiatal hernia, and Nissen fundoplication. We present the case of a 44-year-old Italian woman with a 20-year history of gastroesophageal reflux disease refractory to medical treatment, who underwent robotic Nissen fundoplication. In our center, we use the da Vinci® Xi™ Surgical System, which is an advanced tool for minimally invasive surgery. Conclusions: Various reports published in the literature suggested that the robot-assisted approach was effective and was associated with very low postoperative morbidity and was accompanied by satisfactory symptomatic and anatomical radiological outcomes during a follow-up period. The robotic approach to paraesophageal repair is safe and effective with low complication rates. With increased experience, the operative time, length of stay, and complications decrease without compromising surgical principles.
MeSH term(s)	Adult ; Esophagogastric Junction/diagnostic imaging ; Esophagogastric Junction/pathology ; Female ; Fundoplication/methods ; Gastroesophageal Reflux/complications ; Hernia, Hiatal/classification ; Hernia, Hiatal/surgery ; Humans ; Radiography ; Robotic Surgical Procedures/methods
Language	English
Publishing date	2020-02-04
Publishing country	England
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2269805-X
ISSN	1752-1947 ; 1752-1947
ISSN (online)	1752-1947
ISSN	1752-1947
DOI	10.1186/s13256-020-2347-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Surgical management of non-parasitic hepatic cysts A single center experience and a review of the literature.

Tartaglia, Nicola / Di Lascia, Alessandra / Cianci, Pasquale / Vovola, Fernanda / Pacilli, Mario / Zita, Antonio / Fersini, Alberto / Ambrosi, Antonio

Annali italiani di chirurgia

2019 Volume 90, Page(s) 514–519

Abstract: Aim: We present our experience in the laparoscopic management of the hepatic cysts (SHCs) and the polycystic liver disease (PCLD), and a literature review.: Material and methods: Between 2005 and 2018, laparoscopic deroofing was performed in 28 ... ...

Abstract	Aim: We present our experience in the laparoscopic management of the hepatic cysts (SHCs) and the polycystic liver disease (PCLD), and a literature review. Material and methods: Between 2005 and 2018, laparoscopic deroofing was performed in 28 consecutive patients. There were 19 cases with SHCs and only 9 cases with PCLD (Gigot's type I). CT scan was performed in all cases to assess the characteristics, dimensions, and exact position of the lesion. Surgery was planned for all patients because of evident and persistent symptomatology, RESULTS: We have analyzed operative time, surgical procedure, blood loss, hospital stay, complications, and medium follow- up period. All the patients underwent laparoscopic deroofing of the larger cysts and puncturing of the smaller cysts. The total morbidity recorded was 25% (7/28), 3 cases in the group of SHCs (16 %) and 4 cases in the PCLD one (44%) and was characterized of 3 cases of ascites through trocar insertion sites after removal of drainage tube and 4 case of pleural effusion. Discussion: There were no significant group differences in term of length of hospital stay. The follow-up period (a mean of 24 months) confirmed that all the patients remained free of symptoms and relapse of the disease. Conclusion: The technical feasibility and the good short- and medium-term results made the laparoscopic approach the procedure of choice for the management of symptomatic liver cysts. Key words: Hepatic cyst, Liver disease, Minimally invasive surgery.
MeSH term(s)	Adult ; Ascites/etiology ; Cysts/complications ; Cysts/diagnostic imaging ; Cysts/surgery ; Feasibility Studies ; Female ; Follow-Up Studies ; Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Length of Stay/statistics & numerical data ; Liver Diseases/complications ; Liver Diseases/diagnostic imaging ; Liver Diseases/surgery ; Male ; Middle Aged ; Operative Time ; Pleural Effusion/etiology ; Postoperative Complications/etiology ; Retrospective Studies ; Tomography, X-Ray Computed ; Ultrasonography
Language	English
Publishing date	2019-09-30
Publishing country	Italy
Document type	Evaluation Study ; Journal Article ; Review
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Rare Case of Functioning Adrenocortical Oncocytoma Presenting as Cushing Syndrome.

Tartaglia, Nicola / Cianci, Pasquale / Altamura, Amedeo / Lizzi, Vincenzo / Vovola, Fernanda / Fersini, Alberto / Ambrosi, Antonio / Neri, Vincenzo

Case reports in surgery

2016 Volume 2016, Page(s) 8964070

Abstract: Functioning adrenocortical oncocytoma is very rare neoplasm. It is usually nonfunctional and benign and incidentally detected. Generally, these tumors originate in the kidneys, thyroid, parathyroid, and salivary or pituitary glands; they have also been ... ...

Abstract	Functioning adrenocortical oncocytoma is very rare neoplasm. It is usually nonfunctional and benign and incidentally detected. Generally, these tumors originate in the kidneys, thyroid, parathyroid, and salivary or pituitary glands; they have also been reported in other sites including choroid plexus, respiratory tract, and larynx. Histologically, they are characterized by cells with eosinophilic granular cytoplasm and numerous packed mitochondria. We reported a case of a 44-year-old female who presented with Cushing syndrome for hypersecretion of cortisol due to adrenocortical oncocytoma. Magnetic resonance of abdomen revealed a right adrenal mass. Laparoscopic adrenalectomy was performed and the tumor was pathologically confirmed as benign adrenocortical oncocytoma. After surgical treatment, Cushing's syndrome resolved.
Language	English
Publishing date	2016-02-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2657697-1
ISSN	2090-6919 ; 2090-6900
ISSN (online)	2090-6919
ISSN	2090-6900
DOI	10.1155/2016/8964070
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A recurrent epidermoid cyst of the spleen: report of a case and literature review.

Cianci, Pasquale / Tartaglia, Nicola / Altamura, Amedeo / Fersini, Alberto / Vovola, Fernanda / Sanguedolce, Francesca / Ambrosi, Antonio / Neri, Vincenzo

World journal of surgical oncology

2016 Volume 14, Page(s) 98

Abstract: Background: Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, ... ...

Abstract	Background: Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation: We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions: Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary.
MeSH term(s)	Adult ; Epidermal Cyst/pathology ; Epidermal Cyst/surgery ; Female ; Humans ; Laparoscopy ; Prognosis ; Recurrence ; Splenectomy ; Splenic Diseases/pathology ; Splenic Diseases/surgery ; Young Adult
Language	English
Publishing date	2016-04-01
Publishing country	England
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2118383-1
ISSN	1477-7819 ; 1477-7819
ISSN (online)	1477-7819
ISSN	1477-7819
DOI	10.1186/s12957-016-0857-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

Nepogodiev, Dmitri / Glasbey, James C / Li, Elizabeth / Omar, Omar M / Simoes, Joana FF / Abbott, Tom EF / Alser, Osaid / Arnaud, Alexis P / Bankhead-Kendall, Brittany K / Breen, Kerry A / Cunha, Miguel F / Davidson, Giana H / Di Saverio, Salomone / Gallo, Gaetano / Griffiths, Ewen A / Gujjuri, Rohan R / Hutchinson, Peter J / Kaafarani, Haytham MA / Lederhuber, Hans /

Löffler, Markus W / Mashbari, Hassan N / Minaya-Bravo, Ana / Morton, Dion G / Moszkowicz, David / Pata, Francesco / Tsoulfas, George / Venn, Mary L / Bhangu, Aneel / Cox, Daniel / Roslani, April C / Alakaloko, Felix / de Vries, Jean-Paul PM / Aaraj, Mahmoud A / Abbott, Sarah J / Abdalla, Mutwakil OM / Abdelaal, Ahmed S / Ademuyiwa, Adesoji O / Aherne, Thomas M / Ali, Osman M / Alkadeeki, Ghadah Z / Almeida, Ana C / Alrahawy, Mahmoud M / Ambler, Graeme K / Alameer, Ehab / Andreani, Stefano M / De Andrés-Asenjo, Beatriz / Antonanzas, Leyre Lopez / Aoun, Salah G / Ashoush, Fouad M / Augestad, Knut Magne / Avellana, Rocio B / Ayeni, Funbi A / Ayorinde, John OO / Babu, Bheemanakone H / Baig, Mirza MAS / Bajomo, Oreoluwa M / Baker, Olivia J / Baker, Markus P / Baldwin, Alexander J / Ban, Vin Shen / Baron, Ryan D / Barranquero, Alberto G / Barry, Conor P / DI Bartolomeo, Alessandro / Bass, Gary A / Bath, Michael F / Batjer, H Hunt / Beamish, Andrew J / Belgaumkar, Ajay P / Bence, Matthew N / Benson, Ruth A / Bernal-Sprekelsen, Juan Carlos / Bhama, Anuradha R / Bhavaraju, Avi V / Biffl, Walter L / Blundell, Chris M / Boddy, Alexander P / Borgstein, Alexander BJ / Bosanquet, David C / Bosch, Karen D / Bouhuwaish, Ahmad EM / Bozkurt, Mehmet A / Brathwaite, Collin EM / Brown, Benjamin C / Brown, Oliver D / Brown, Allison K / Buarque, Igor Lima / Bueno-Cañones, Alejandro D / Bulugma, Mustafa R / Burke, Joshua R / Byrne, Matthew HV / Cagigal-Ortega, Elima P / Callcut, Rachael A / DI Candido, Francesca / Canova, Michaela E / Carlos, William J / Caruana, Edward J / Cato, Liam D / Catton, Andrew B / Ceretti, Andrea Pisani / Chase, Thomas JG / Chiara, Francesco Di / Chowdhury, Abeed H / Chung, Eric A / Cicerchia, Pierfranco M / Clough, Ethan CS / Coleman, Natasha L / Collins, Chris G / Collins, Michelle L / Colonna, Emily T / Comini, Lara V / Connolly, Tara M / Coughlin, Patrick A / Cruzado, Laura Fernández-Gomez / Davidson, Brian R / Davies, Richard J / Davies, Emma J / Davis, Niall F / Dawson, Brett E / Dean, Benjamin JF / Delgado, Maria Garcia-Conde / Diaz, Jose J / Dickson, Kathryn E / Diez-Alonso, Manuel M / Dixon, Jan R / Doe, Matthew J / Drake, Thomas D / Drake, Frederick T / Duffy, John P / Dunne, Declan FJ / Dunne, Naomi JM / Durán-Muñoz-Cruzado, Virginia M / Durst, Alexander ZE / Eardley, Nicola J / Edwards, John G / Elfallal, Ahmed H / Elfiky, Mahmoud MA / Elliott, Jessie A / Emile, Sameh H / Emslie, Katy M / Endorf, Frederick W / Engel, Jamie L / Enjuto, Diego T / Etchill, Eric W / Evans, Jonathan P / Fahey, Brian A / Faria, Carlos S / Feo, Carlo V / Ferguson, Henry JM / Fernandez, Beatriz Dieguez / Fernandez, Andres Garcia / Fernández, Antonio J / Fernández-Pacheco, Borja Camacho / Fitzgerald, J Edward / Fonsi, Giovanni B / Font, Roser Farré / Fowler, Amy L / Franco, Gregorio Di / Fretwell, Kenneth R / Fructuoso, Lorena Sanchon / Fusai, Giuseppe K / Garcia, Miguel Hernandez / Garcia-Ureña, Miguel Angel / Gill, Charn K / Gisbertz, Suzanne S / Del Giudice, Roberto / Giuffrida, Maria Carmela / Di Giuseppe, Matteo / Gómez, María Fanjul / González, Javier Serrano / Guariglia, Claudio A / Hainsworth, Alison J / Hall, Bria J / Hall, James RW / Hammond, John S / Haqqani, Maha H / Harrison, Ewen M / Hazelton, Joshua P / van Heinsbergen, Maarten / Hill, Arnold DK / Hing, Caroline B / Hirji, Sameer A / Ho, Michael WS / Holbrook, Charlotte M / Holme, Thomas J / Hopkins, James C / Hopkinson, David N / Hossain, Fahad S / Hudson, Victoria E / Hughes, Jane L / Hwang, E. Shelley / Ibrahim, Mohamed AH / Isolani, Simone M / Jara, Pablo Galindo / Jenkinson, Michael D / Jenny, Hillary E / Jeyaretna, Deva S / Jones, Robert P / Jones, Andrew P / Jonker, Pascal KC / Jönsson, Maria L / Joyce, Doireann P / Kalkwarf, Kyle J / Kamarajah, Sivesh K / El Kassas, Mohamed / Kavanagh, Dara O / Keatley, James M / Khalefa, Mohamed A / Khan, Jim S / Kirmani, Bilal H / Kisiel, Aaron P / Kouris, Spyros Marinos / Kowal, Mikolaj R / Labib, Peter L / Larkin, John O / Lauscher, Johannes C / Leclercq, Wouter KG / Ledesma, Frances SJ / Leite-Moreira, André M / Leung, Elaine YL / Lewis, Sophia E / Lima, Maria João / Lin, Daniel J / Liu, Helen H / Lowery, Aoife J / Lozano, Saida Martel / Luney, Catriona R / Maia, Mariana Magalhães / Mariani, Nicolò M / Marino, Marco V / Marra, Angelo A / Marsh, Christopher L / Martin, Robert CG / McCluney, Simon J / McIntyre, Robert C / Mckay, Siobhan C / McKevitt, Kevin L / Meagher, Ashley D / Mehdi, Mohammad Q / Mehigan, Brian J / Gonzalez-De Miguel, Melania / De Miguel-Ardevines, Maria-Carmen / Miguel-Mendez, Carlos San / Mills, Sarah J / Mohan, Helen M / Moir, John AG / Monson, John RT / Monteiro, Joana M / Montella, Maria T / Montesinos, Cristina Soto / Morgom, Marwa M / Moura, Francisco S / Muguerza, Jose M / Murphy, Suzanne H / De Nardi, Paola / Naumann, David N / Neary, Paul C / Neely, David TA / Ng-Kamstra, Joshua S / Ngu, Albert WT / Nguyen, Truong A / Nita, George E / Nunes, Quentin M / Nygaard, Rachel M / O'Meara, Lindsay B / O'Neill, John R / Okafor, Barbara U / Olson, Steven A / Oo, Aung Y / Ormazabal, Pablo Collera / Osorio, Alexander L / Pachl, Max J / Parry, James T / Patel, Panna K / Pérez, David Díaz / Pérez, Carolina Martínez / Pérez-Sánchez, Luis E / Pevidal, Ana Nogues / Pezzuto, Anna P / Philp, Matthew M / Pinkney, Thomas D / Pollok, Joerg M / Povey, Meical G / Poza, Alfredo Alonso / Rajgor, Amarkumar D / Rao, Jagan N / Raptis, Dimitri A / Rice, Henry E / Ridgway, Paul F / Rivas, Ana Munoz / Rodriguez-Sanjuan, Juan C / Rogers, Luke J / Da Roit, Anna / Rollett, Rebecca A / Romera, Jose L / Rooney, Siobhan M / Roxo, Vanessa I / Le Roy, Bertrand / Rubio, Eduardo E / Ruiz, Carolina Castro / Ruiz, Manuel Losada / Ryan, Éanna J / Saad, Abdel Rahman / Saeed, Samerah A / Salama, Hiba A / Salamah, Abdulrauf A / Samaniego, María Gutiérrez / Sampietro, Gianluca M / Sarma, Diwakar R / Schaffer, Kathryn B / Schnitzbauer, Andreas A / Scurrah, Rachel J / Serevina, Olivia L / Serralheiro, Pedro A / Sewards, Joseph M / Shackcloth, Michael J / Shaw, Abigail V / Sheel, Andrea RG / Sica, Giuseppe S / De Simone, Veronica / Singh, Aminder A / Singh, Rabindra P / Skelly, Brendan L / Smith, Henry G / Sohail, Amir H / Spalding, Duncan R / Springford, Laurie R / Ssentongo, Anna E / Steinkamp, Pieter J / Stevens, Kent A / Stewart, Grant D / Stylianides, Nicholas A / Sullivan, Tom BB / Taher, Ahmed SA / Tamimy, Muhammad S / Tang, Alethea M / Tebala, Giovanni D / Tejero-Pintor, Francisco J / Thaha, Mohamed A / Thomas, Amy J / De Toma, Giorgio / La Torre, Filippo / Torres, Antonio J / Townshend, David N / Trout, Isobel M / Tucker, Sarah C / Ubhi, Harmony K / Vega, Viviana A / Velmahos, George C / Velopulos, Catherine G / Viswanath, Yirupaiahgari KS / Vivas, Alfredo A / Wade, Ryckie G / Wadley, Martin S / Wall, Joshua JS / Walters, Andrew M / Warren, Oliver J / Weerasinghe, Chamindri K / Wilkin, Richard JW / Williams, Katherine J / Winter, Stuart C / Wormald, Justin CR / Wright, Franklin L / Xyda, Souzana E / Young, Alastair L / Youssef, Mina MG / Yousuf, Farhat B / El Youzouri, Hanan / Zappa, Marco A / Abate, Emmanuele / Abdalaziz, Hossam / Abdelkarim, Mostafa / Abdou, Hossam / Aboelkassem-Ibrahim, Ahmad / Abuown, Ala / Acebes-Garcia, Fernando / Acharya, Metesh / Adamina, Michel / Addae-Boateng, Emmanuel / Aftab, Raiyyan / Agarwal, Arnav / Aguilar, José / Ahmed, Yousra / Aitken, Emma / Al-Azzawi, Marwa / Al-Embideen, Somya / Al-Masri, Mahmoud / Al-Najjar, Hani / Al-Sukaini, Ahmad / Alam, Ruhina / Alderson, Derek / Aliyeva, Zumrud / Aljanadi, Firas / Almasri, Murad / Alonso-Ortuño, Paula / Altintoprak, Fatih / Amira, Gamal / Amjad, Rabbia / Anania, Gabriele / Andabaka, Tatjana / Angelou, Dimitrios / Annamalai, Seethalakshmi / Annessi, Valerio / Anthoney, James / Anwar, Sibtain / Anwer, Mariyah / Aragon-Chamizo, Juan / Ardito, Antonella / Arigoni, Michele / Armao, Teodora / Arminio, Armando / Armstrong, Lara / Arnaud, Alexis / Asaad, Peter / Ashcroft, James / Ashmore, Christopher / Asqalan, Ahmad / Asti, Emanuele / Aubry, Emmanuelle / Aytac, Erman / Ayuso-Herrera, Esther / Baeza, Melody / Bailon-Cuadrado, Martin / Bakmaz, Bernarda / Baldi, Caterina / Baldini, Edoardo / Baldo, Stefano / Ballabio, Michele / Baloyiannis, Ioannis / Baltazar, Gerard / Bàmbina, Fabrizio / Bandiera, Alessandro / Barlow, Emma / Barmasse, Roberto / Barmpagianni, Christina / Baronio, Gianluca / Barra, Fabio / Bartsch, Anne-Marie / Basgaran, Amedra / Basha, Amr / Bashkirova, Varvara / Bastazza, Marco / Baumber, Rachel / Belcher, Elizabeth / Belvedere, Angela / Benítez-Linero, Inmaculada / Bergeat, Damien / Bernasconi, Matteo / Bhalla, Ashish / Bhutiani, Neal / Bianco, Federica / Bisagni, Pietro / Blake, Iain / Blanco-Colino, Ruth / Blazquez-Martin, Alma / Boal, Matthew / Bonavina, Luigi / Bonavina, Giulia / Bond-Smith, Giles / Booth, Karen / Borges, Filipe / Borghi, Felice / Bouchagier, Konstantinos / Bourke, Grainne / Boyle, Emily / Brachini, Gioia / Brain, Jessie / Brar, Amanpreet / Breckles, Lisa / Bretagnol, Frédéric / Brixton, Genevieve / Bruzzaniti, Placido / Bueser, Teofila / Burnside, Nathan / Caballero, Albert / Calcerrada-Alises, Enrique / Callahan, Miriam / Camarero, Enrique / Campagnaro, Tommaso / Campanelli, Michela / Candiani, Massimo / Cannoletta, Marina / Cantalejo-Diaz, Miguel / Cao, Han / Capelli, Patrizio / Capizzi, Vita / Carcano, Giulio / Carissimi, Francesca / Carlini, Massimo / Carlucci, Michele / Carmichael, Heather / Carrasco, Milagros / Carrillo, Mariana / Carvello, Michele / Casati, Massimiliano / Castoro, Carlo / Catalan, Vanesa / Cavaleiro, Salomé / Cellerino, Paola / Centinaio, Giovanna / Cernei, Cristina / Cerro, Cristina / Cervellera, Maurizio / Chakrabortee, Sohini / Chamberlain, Stephanie / Chan, Jeffrey / Chang, Grace / Chaudhry, Dauod / Chebaro, Alexandre / Chen, David / Chetty, Govind / Chia, Zoe / Chiappini, Ambra / Chiarugi, Massimo / Chidambaram, Swathikan / Chiozza, Matteo / Cholewa, Hanna / Chong, Clara / Choolani-Bhojwani, Ekta / Christoforidis, Dimitri / Chui, Karen / Chung, Choyin / Cirillo, Bruno / Citterio, Davide / Clermidi, Pauline / Coccolini, Federico / Colletti, Gaia / Compagnoni, Bruno / Concepción-Martín, Vanesa / Confalonieri, Marco / Connolly, Hannah / Conso, Christel / Conti, Luigi / Cooper, Zara / Corbellin, Carlo / Cordera, Fernando / Corral, Javier / Costa, Marta / Costanzi, Andrea / Cotsoglou, Christian / Cozza, Valerio / Cuming, Tamzin / Curtis, Miles / Cuschieri, Joseph / D'Agruma, Michele / D'Andrea, Giancarlo / Daliya, Prita / Dare, Oliver / Darko, Ebenezer / Day, Andrew / Dehal, Ahmed / Dehart, Dustin / Delgado-Oliver, Eduardo / Denning, Max / Desai, Anant / Desender, Liesbeth / Dester, Sara / Díaz-García, Alberto / Diaz-Peña, Patricia / Dousset, Bertrand / Doussot, Alexandre / Duchateau, Nicolas / Duff, Sarah / Dunning, Joel / Duque-Mallen, Victoria / Dziakova, Jana / Egan, Bridget / Egan, Richard / El-Ali, Abess / Elfeki, Hossam / Elhadi, Muhammed / Eljareh, Mohammed / Elkadi, Hannah / Elkady, Ramy / Elkhafeefi, Fatimah / Elmore, Ugo / Elmoslemany, Tarek / Emmerson, Oliver / Enemosah, Ibrahim / English, Camilla / English, William / Ereidge, Simon / Escartin, Jorge / Estaire-Gomez, Mercedes / Evans, Luke / Evans, Jessica / Exley, Rebecca / Fabbri, Nicoló / Falco, Giuseppe / Familiari, Pietro / Fancellu, Alessandro / Farik, Shebani / Farrell, Tony / Fehervari, Matyas / Fell, Adam / Fernandez-Camuñas, Angel / Fernández-Marín, Reyes / Fernández-Martínez, María / Ferrara, Francesco / Ferrari, Guglielmo / Ferrero, Simone / Findlay, Laura / Fiore, Marco / Fiori, Enrico / Flatman, Michael / Flindall, Ian / Flor, Blas / Fontana, Tommaso / Ford, Samuel / Ford, David / Forlani, Stefano / Francone, Elisa / Frattaruolo, Colomba / Frio, Federico / Gagliano, Annalisa / Gagliardi, Filippo / Gahunia, Sukhpreet / Gaino, Francesca / Gala, Tanzeela / Galfrascoli, Elisa / Galimberti, Luca / Gallagher, Phoebe / Galleano, Raffaele / Galván-Pérez, Armando / Gammeri, Emanuele / Ganau, Mario / Garcés-García, Raúl / Garulli, Gianluca / Gascon-Ferrer, Isabel / Gattolin, Andrea / Gaujoux, Sebastien / Gentilli, Sergio / Georgiades, Fanourios / Ghanbari, Amir / Ghosh, Dhruv / Giacometti, Marco / Giblin, Anna-Victoria / Gilbert, Catherine / Giménez, Clara / Giorgakis, Emmanouil / Gipponi, Manuel / Glen, Paul / Goatly, Giles / Gobatti, Davide / Godbole, Chintamani / Gohil, Kajal / Gómez, Marcos / Gomez-Rosado, Juan-Carlos / Gonullu, Emre / Gonzalez-Gonzalez, Enrique / Gordini, Luca / Gracia, Isabel / Gracia-Roche, Carlos / Granieri, Stefano / Green, Susanna / Grivon, Manuela / Grove, Thomas / Guaglio, Marcello / Guaitoli, Eleonora / Guglielmi, Alfredo / Guha, Soumya / Gustavino, Claudio / Habeeb, Amir / Hagger, Robert / Hakmi, Hazim / Halkias, Constantine / Hall, Claire / Hampton, Matthew / Handa, Siddhartha / Hansen, Laura / Haq, Iram / Harky, Amer / Harries, Rhiannon / Harrison, Joseph / Hasan, Raashad / Hawari, Mohammad / Hawkin, Paul / Hebblethwaite, Bethany / Henriques, Susana / Heritage, Emily / Hernandez-Juara, Pilar / Herrero-Lopez, Maria / Hervieux, Erik / Heyd, Bruno / Higgs, Simon / Hitchman, Louise / Ho, Beatrice / Hogan, Aisling / Hölzle, Frank / Hossain, Tanvir / Houston, Roy / Hurt, Libor / Hutchinson, Peter / Iacob, Giulio / Iannone, Immacolata / Ibrahim, Sherif / Iovino, Domenico / Isik, Arda / Jafarova, Sevda / Jamil, Tahir / Jayaraju, Ullas / Jenner, Edward / Jimenez-Higuera, Elisa / Jimeno, Jaime / Johnstone, Jack / Jones, Mark / Judkins, Nicholas / Kalavrezos, Nicholas / Kalidindi, Venugopala / Kalkat, Maninder / Kamal, Mona / Kamphues, Carsten / Kang, Chong / Kara, Yasin / Karam, Edward / Karim, Ahmed / Kashora, Florence / Kearney, David / Khajuria, Apoorva / Khan, Umul / Khan, Azam / Khatri, Chetan / Kinnaman, Gabriel / Kinross, James / Kler, Aaron / Klimopoulos, Serafeim / Kocataş, Ali / Kolias, Angelos / Königsrainer, Alfred / Konsten, Joop / Kontovounisios, Christos / Kourdouli, Amar / Krishnan, Emily / Kristinsson, Sverrir / Kruijff, Schelto / Kudsk-Iversen, Søren / Kufeji, Dorothy / Kugler, Nadav / Kulkarni, Rugved / Kurihara, Hayato / Laface, Letizia / Lakkis, Zaher / Lami, Mariam / Landaluce-Olavarria, Aitor / Lapolla, Pierfrancesco / Lawani, Ismail / Lawday, Samuel / Lázaro, André / Lecolle, Katia / Leventoglu, Sezai / Li, Zoe / Liew, Ignatius / Lisi, Giorgio / Lizzi, Vincenzo / Lo, Terence / Lomiento, Daniele / Longhi, Marco / Lostis, Emilie / Lostoridis, Eftychios / Loubani, Mahmoud / Lowy-Benoliel, Alejandro / Lucianetti, Alessandro / Luke, Louis / Lunevicius, Raimundas / Luraghi, Marco / Lye, George / Mabrouk, Islam / Macchi, Alberto / MacDonald, Luisa / Machairas, Nikolaos / Madonini, Marco / Magowan, Drew / Maisonneuve, Emeline / Majkowska, Agata / Majkowski, Lawrence / Mak, Jason / Malabarba, Stefano / Malerba, Michele / Mannan, Syed / Manson, Joanna / Mansuri, Ahmer / Mantoglu, Baris / Manu, Nichola / Maqsood, Afnan / Marano, Alessandra / Marchbank, Adrian / Marcos-Santos, Pablo / Marrano, Enrico / Martin, Janet / Martin, Emmeline / Martin, Guy / Martin-Albo, Lorena / Martín-Román, Lorena / Martinelli, Fabio / Martínez-dePaz, Fernando / Martinez-German, Antonio / Martinez-Pinedo, Carlos / Martins, Ricardo / Marwan, Hisham / Marzi, Federica / Mateos-Sierra, Olga / Mathieu, Pierre / Matute-Najarro, Maria-Soledad / Maw, Andrew / Mazingi, Dennis / Mazzaferro, Vincenzo / McCanny, Andrew / McKenzie, Katherine / McLarty, Nicola / McPherson, Iain / Medina, Esther / Mediratta, Saniya / Medone, Marzia / Mehra, Gautam / Mele, Simone / Melero-Cortés, Lidia / Mendoza-Moreno, Fernando / Meneghini, Simona / Mercante, Giuseppe / Merdrignac, Aude / Merola, Stephen / Metallidis, Symeon / Michel, Martin / Migliore, Marco / Mihanovic, Jakov / Miller, Douglas / Mingoli, Andrea / Minto, Gary / Mirabella, Antonello / Misra, Nikhil / Mitrasinovic, Stefan / Miu, Victor / Moawad, Nader / Mochet, Sylvie / Modabber, Ali / Mohammad, Adam / Mohan, Midhun / Moliner-Sánchez, Carmen / Mongelli, Francesco / Monteleone, Michela / Montuori, Mauro / Moore, Rachel / Mora-Guzmán, Ismael / Morales, Xavier / Morales, Dieter / Morelli, Luca / Morelli, Lucia / Morgan, Richard / Morris, Chris / Mortini, Pietro / Mosca, Angelo / Motter, Dema / Moug, Susan / Mukherjee, Samrat / Najdy, Manhal / Nakas, Apostolos / Namazov, Ilgar / Naredla, Pradyumna / Nasef, Emmhamed / Nassa, Heeam / Nath, Rahul / Navarro-Sánchez, Antonio / Nazarian, Scarlet / Negri, Giampiero / Nehra, Deepika / Neil-Dwyer, Jason / Neri, Jacopo / Newton, Katy / Nikaj, Herald / Niquen, Milagros / Nobile, Sara / Nogueiro, Jorge / Ntirenganya, Faustin / Nugent, Michael / Núñez, Jordi / Ocaña, Juan / Okechukwu, Valentine / Oliva-Mompean, Fernando / Oliveira, Ana / Ollat, Didier / Onos, Lavinia / Osagie-Clouard, Liza / Osman, Khabab / Ottolina, Jessica / Ourieff, Jared / Outani, Oumaima / Oyewole, Bankole / Ozben, Volkan / Pacheco-Sanchez, David / Padilla-Valverde, David / Pai, Madhava / Paiella, Salvatore / Paisley, Samuel / Palini, Gianmarco / Palmeri, Matteo / Panahi, Pedram / Parente, Alessandro / Parlanti, Daniele / Parmar, Chetan / Pascual, Angela / Patel, Mahul / Pathak, Abhijit / Patil, Sangram / Pattyn, Piet / Peckham-Cooper, Adam / Pedrazzani, Corrado / Pellino, Gianluca / Peluso, Chiara / Pereira, André / Pereira-Neves, António / Perez-Diaz, Md / Pérez-González, Marta / Pérez-Saborido, Baltasar / Perivoliotis, Konstantinos / Perkins, Clare / Peros, Georgios / Perotto, Ornella / Perra, Teresa / Petrone, Patrizio / Phenix, George / Picazo, Sara / Picon-Rodriguez, Rafael / Piloni, Martina / Pingarrón-Martín, Lorena / Pinotti, Enrico / Pisanu, Adolfo / Pizzini, Paolo / Pockney, Peter / Podda, Mauro / Podolsky, Dina / Poggioli, Gilberto / Pompili, Cecilia / Pontari, Michael / Porcu, Alberto / Potter, Ryan / Price, Claire / Pruvot, François-René / Pujol-Muncunill, Roger / Puppo, Andrea / Quante, Markus / Quintana-Villamandos, Begoña / Qureshi, Ali / Radenkovic, Dejan / Rakvin, Ivan / Ramallo-Solís, Irene / Ramcharan, Sean / Ramos, Diego / Ramos-Bonilla, Antonio / Ramzi, Joussi / Rathinam, Sridhar / Rausa, Emanuele / Ravaioli, Matteo / Ravindran, Sharanya / Raymond, Thomas / Razik, Aisha / Redfern, Jennifer / Reguera-Rosal, Julio / Rela, Mariam / Rey-Biel, Juan / Rey-Valcarcel, Cristina / Ribolla, Marta / Richards, Tomos / Richmond, Michael / Righini, Erminio / Rio-Gomez, Javier / Riyat, Harjoat / Rizvi, Sana / Roberts, Keith / Roberts, Matthew / Robertson, Stuart / Robertson, Ronald / Robin-Valle, Alvaro / Rochon, Melissa / Rojo, Mikel / Rolli, Luigi / Romano, Silvio / Ross, Elizabeth / Ross, Howard / Rossborough, Catherine / Rottoli, Matteo / Ruiz, Miguel / Ruiz-Grande, Fernando / Ruiz-Martin, Irene / Ruiz-Soriano, María / Ruzzenente, Andrea / Ryska, Ondrej / Saez, Carlos / Sagnotta, Andrea / Sahnan, Kapil / Sahni, Arun / Salim, Ali / Sallam, Ibrahim / Salvia, Roberto / Samadov, Elgun / Sammarco, Giuseppe / Sampaio-Alves, Mafalda / Sánchez-Arteaga, Alejandro / Sanchez-Fuentes, Maria-Nieves / Sanchez-Pelaez, Daniel / Sanchez-Perez, Coral / Sanchez-Rubio, Maria / Sancho-Muriel, Jorge / Sanders, Julie / Santero-Ramirez, Maria-Pilar / Santora, Thomas / Santoro, Antonio / Santos, Irene / Santos-Sousa, Hugo / Sapienza, Paolo / Sartarelli, Lodovico / Sarveswaran, Janahan / Sasia, Diego / Saudemont, Alain / Saudi-Moro, Sef / Saxena, Shobhit / Saxena, Dolly / Sayasneh, Ahmad / Scalabre, Aurelien / Schache, Andrew / Schiavina, Riccardo / Schineis, Christian / Schreckenbach, Teresa / Scorza, Antonella / Scott, Lucy / Seegert, Sara / Seguin-Givelet, Agathe / Senent-Boza, Ana / Seymour, Keith / Shabana, Amanda / Shah, Karishma / Shah, Jigar / Shah, Preena / Shah, Sujay / Shakir, Taner / Shalaby, Mostafa / Shankar, Sushma / Shaw, Richard / Shehata, Sameh / Shenfine, Amy / Sheridan, Kelda / Sherief, Ahmed / Sherief, Mohamed / Sherif, Mohamed / Shinkwin, Michael / Shu, Sebastian / Siaw-Acheampong, Kwabena / Sileri, Pierpaolo / Singh, Abhinav / Singh, Shailendra / Sinha, Sanjay / Sinha, Deepti / Siragusa, Leandro / Sivaprakasam, Rajesh / Sivayoganathan, Sriharan / Smillie, Robert / Smith, Claire / Smith, Andrew / Smith, Christopher / Sochorova, Dana / Soggiu, Fiammetta / Sohrabi, Catrin / Solari, Francesca / Solli, Piergiorgio / Soreide, Kjetil / Spinelli, Antonino / Spoletini, Domenico / Spriano, Giuseppe / Sravanam, Sanskrithi / Ssentongo, Paddy / Stanger, Sophie / Stavroulias, Dionisios / Steel, Ben / Stella, Marco / Stewart, Robbie / Stringer, Sally / Sulen, Nina / Sundar, Sudha / Sundhu, Matthew / Suri, Avni / Syed, Arooj / Szatmary, Peter / Tabiri, Stephen / Tadross, Daniel / Taglietti, Lucio / Tansey, Rosamond / Tartaglia, Dario / Tawheed, Ahmed / Tayeh, Salim / Teles, Tobias / Testa, Valentina / Tewari, Nilanjana / Thoenissen, Philipp / Thomas, Kane / Thomin, Anne / Thrush, Jessica / Tierney, Sean / Tiwari, Abhinav / Toh, Simon / Toledo, Enrique / Tonini, Valeria / Torkington, Jared / Torquati, Alfonso / Torzilli, Guido / Totty, Joshua / Tourountzi, Paraskevi / Tousidonis, Manuel / Townend, Philip / Townsend, Catherine / Trompeter, Alex / Trotta, Francesco / Truant, Stéphanie / Trujillo-Díaz, Jeancarlos / Tsoulfas, Georgios / Turco, Celia / Turrado-Rodriguez, Victor / Turri, Giulia / Tustin, Harry / Tyler, Jayne / Tzedakis, Stylianos / Tzovaras, George / Uittenbogaart, Martine / Ullah, Ramzan / Urban, Shane / Urbani, Alessia / Usai, Antonella / Vaccarella, Gianpaolo / Valdes-Hernandez, Javier / Valsecchi, Luca / Vashisht, Rajiv / Vázquez-Fernández, Andrea / Venkatesan, Gowtham / Venn, Mary / Vera-Mansilla, Cristina / Vergari, Roberto / Vescio, Giuseppina / Vidya, Raghavan / Vieira, Paula / Vijay, Vardhini / Vimalachandran, Dale / Violante, Tommaso / Volpe, Anita / Vovola, Fernanda / Vulliamy, Paul / Wall, Rosemary / Wallwork, Kate / Ward, Alex / Warwick, David / Waseem, Saima / Weaver, Helen / Wells, Fiona / Wen, Jiaxin / West, Raha / Whitehall, Emma / Wild, Laura / Wilkins, Alex / Williams, Gethin / Williams, Matthew / Winnand, Philipp / Wong, Ken / Worku, Dawit / Wright, Naomi / Yalamanchili, Seema / Yershov, Danylo / Yildiz, Alp / Young, Richard / Yurttas, Can / Zadegan, Frederic / Zafar, Noman / Zakaria, Rasheed / Zambon, Martina / Zanini, Nicola / Zarate, Alba / Zerbib, Philippe / Zizzo, Maurizio / Zmora, Oded / Zonta, Sandro / van Berge Henegouwen, Mark I / van der Plas, Willemijn Y / Ali, Inthekab Ali Mohamed / Bakri, Nur Amalina Che / Bartolomé, Miguel Ángel Hernández / Bauset, Juan Carlos Catalá / Abou Chaar, Mohamad K / Marino Cosentino, Luigi MP / Gómez Díaz, Carlos J / Garcia Galocha, Jose L / de Gheldere, Charles A / Ataíde Gomes, Gustavo Mendonça / Beltrán de Heredia, Juan / Blazer, Dan G / Nugent, William C / Ali karar, Ali A / Borja De Lacy, F / Blas Laina, Juan luis / Shane Lester, Madan Jha / Liyanage, Aloka S D / Al Maadany, Faraj S / De Marchi, Joshua A / Ramos-De la Medina, Antonio / Mithany, Reda H M / Sanchez del Pueblo, Cristina / van Ramshorst, Gabrielle H / De Salas, Maria Marqueta / De Souza, Anthony C / Dolores Del Toro, M

an international cohort study

2020

Abstract: Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

Abstract	Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 82·6% (219 of 265) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28-2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65-3·22], p<0·0001), American Society of Anesthesiologists grades 3-5 versus grades 1-2 (2·35 [1·57-3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01-2·39], p=0·046), emergency versus elective surgery (1·67 [1·06-2·63], p=0·026), and major versus minor surgery (1·52 [1·01-2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.
Keywords	covid19
Subject code	610 ; 616
Language	English
Publishing country	it
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

Nepogodiev, Dmitri / Bhangu, Aneel / Glasbey, James C / Li, Elizabeth / Omar, Omar M / Simoes, Joana FF / Abbott, Tom EF / Alser, Osaid / Arnaud, Alexis P / Bankhead-Kendall, Brittany K / Breen, Kerry A / Cunha, Miguel F / Davidson, Giana H / Di Saverio, Salomone / Gallo, Gaetano / Griffiths, Ewen A / Gujjuri, Rohan R / Hutchinson, Peter J / Kaafarani, Haytham MA /

Lederhuber, Hans / Löffler, Markus W / Mashbari, Hassan N / Minaya-Bravo, Ana / Morton, Dion G / Moszkowicz, David / Pata, Francesco / Tsoulfas, George / Venn, Mary L / Cox, Daniel / Roslani, April C / Alakaloko, Felix / de Vries, Jean-Paul PM / Aaraj, Mahmoud A / Abbott, Sarah J / Abdalla, Mutwakil OM / Abdelaal, Ahmed S / Ademuyiwa, Adesoji O / Aherne, Thomas M / Ali, Osman M / Alkadeeki, Ghadah Z / Almeida, Ana C / Alrahawy, Mahmoud M / Ambler, Graeme K / Alameer, Ehab / Andreani, Stefano M / De Andrés-Asenjo, Beatriz / Antonanzas, Leyre Lopez / Aoun, Salah G / Ashoush, Fouad M / Augestad, Knut Magne / Avellana, Rocio B / Ayeni, Funbi A / Ayorinde, John OO / Babu, Bheemanakone H / Baig, Mirza MAS / Bajomo, Oreoluwa M / Baker, Olivia J / Baker, Markus P / Baldwin, Alexander J / Ban, Vin Shen / Baron, Ryan D / Barranquero, Alberto G / Barry, Conor P / DI Bartolomeo, Alessandro / Bass, Gary A / Bath, Michael F / Batjer, H Hunt / Beamish, Andrew J / Belgaumkar, Ajay P / Bence, Matthew N / Benson, Ruth A / Bernal-Sprekelsen, Juan Carlos / Bhama, Anuradha R / Bhavaraju, Avi V / Biffl, Walter L / Blundell, Chris M / Boddy, Alexander P / Borgstein, Alexander BJ / Bosanquet, David C / Bosch, Karen D / Bouhuwaish, Ahmad EM / Bozkurt, Mehmet A / Brathwaite, Collin EM / Brown, Benjamin C / Brown, Oliver D / Brown, Allison K / Buarque, Igor Lima / Bueno-Cañones, Alejandro D / Bulugma, Mustafa R / Burke, Joshua R / Byrne, Matthew HV / Cagigal-Ortega, Elima P / Callcut, Rachael A / DI Candido, Francesca / Canova, Michaela E / Carlos, William J / Caruana, Edward J / Cato, Liam D / Catton, Andrew B / Ceretti, Andrea Pisani / Chase, Thomas JG / Chiara, Francesco Di / Chowdhury, Abeed H / Chung, Eric A / Cicerchia, Pierfranco M / Clough, Ethan CS / Coleman, Natasha L / Collins, Chris G / Collins, Michelle L / Colonna, Emily T / Comini, Lara V / Coughlin, Patrick A / Cruzado, Laura Fernández-Gomez / Davidson, Brian R / Davies, Richard J / Davies, Emma J / Davis, Niall F / Dawson, Brett E / Dean, Benjamin JF / Delgado, Maria Garcia-Conde / Diaz, Jose J / Dickson, Kathryn E / Diez-Alonso, Manuel M / Dixon, Jan R / Doe, Matthew J / Drake, Thomas D / Drake, Frederick T / Duffy, John P / Dunne, Declan FJ / Dunne, Naomi JM / Durán-Muñoz-Cruzado, Virginia M / Durst, Alexander ZE / Eardley, Nicola J / Edwards, John G / Elfallal, Ahmed H / Elfiky, Mahmoud MA / Elliott, Jessie A / Emile, Sameh H / Emslie, Katy M / Endorf, Frederick W / Engel, Jamie L / Enjuto, Diego T / Etchill, Eric W / Evans, Jonathan P / Fahey, Brian A / Faria, Carlos S / Feo, Carlo V / Ferguson, Henry JM / Fernandez, Beatriz Dieguez / Fernandez, Andres Garcia / Fernández, Antonio J / Fernández-Pacheco, Borja Camacho / Fitzgerald, J Edward / Fonsi, Giovanni B / Font, Roser Farré / Fowler, Amy L / Fretwell, Kenneth R / Fructuoso, Lorena Sanchon / Fusai, Giuseppe K / Garcia, Miguel Hernandez / Garcia-Ureña, Miguel Angel / Gill, Charn K / Gisbertz, Suzanne S / Del Giudice, Roberto / Giuffrida, Maria Carmela / Di Giuseppe, Matteo / Gómez, María Fanjul / Guariglia, Claudio A / Hainsworth, Alison J / Hall, Bria J / Hall, James RW / Hammond, John S / Haqqani, Maha H / Harrison, Ewen M / Hazelton, Joshua P / van Heinsbergen, Maarten / Hill, Arnold DK / Hing, Caroline B / Hirji, Sameer A / Ho, Michael WS / Holbrook, Charlotte M / Holme, Thomas J / Hopkins, James C / Hopkinson, David N / Hossain, Fahad S / Hudson, Victoria E / Hughes, Jane L / Hwang, E. Shelley / Ibrahim, Mohamed AH / Isolani, Simone M / Jenkinson, Michael D / Jenny, Hillary E / Jeyaretna, Deva S / Jones, Robert P / Jones, Andrew P / Jonker, Pascal KC / Jönsson, Maria L / Joyce, Doireann P / Kalkwarf, Kyle J / Kamarajah, Sivesh K / El Kassas, Mohamed / Kavanagh, Dara O / Keatley, James M / Khalefa, Mohamed A / Khan, Jim S / Kirmani, Bilal H / Kisiel, Aaron P / Kouris, Spyros Marinos / Kowal, Mikolaj R / Labib, Peter L / Larkin, John O / Lauscher, Johannes C / Leclercq, Wouter KG / Ledesma, Frances SJ / Leite-Moreira, André M / Leung, Elaine YL / Lewis, Sophia E / Lima, Maria João / Lin, Daniel J / Liu, Helen H / Lowery, Aoife J / Lozano, Saida Martel / Luney, Catriona R / Maia, Mariana Magalhães / Mariani, Nicolò M / Marino, Marco V / Marra, Angelo A / Marsh, Christopher L / Martin, Robert CG / McCluney, Simon J / McIntyre, Robert C / Mckay, Siobhan C / McKevitt, Kevin L / Meagher, Ashley D / Mehdi, Mohammad Q / Mehigan, Brian J / Gonzalez-De Miguel, Melania / De Miguel-Ardevines, Maria-Carmen / Mills, Sarah J / Mohan, Helen M / Moir, John AG / Monson, John RT / Monteiro, Joana M / Montella, Maria T / Montesinos, Cristina Soto / Morgom, Marwa M / Moura, Francisco S / Muguerza, Jose M / Murphy, Suzanne H / De Nardi, Paola / Naumann, David N / Neary, Paul C / Neely, David TA / Ng-Kamstra, Joshua S / Ngu, Albert WT / Nguyen, Truong A / Nita, George E / Nunes, Quentin M / Nygaard, Rachel M / O'Meara, Lindsay B / O'Neill, John R / Okafor, Barbara U / Olson, Steven A / Oo, Aung Y / Ormazabal, Pablo Collera / Osorio, Alexander L / Pachl, Max J / Parry, James T / Patel, Panna K / Pérez-Sánchez, Luis E / Pevidal, Ana Nogues / Pezzuto, Anna P / Philp, Matthew M / Pinkney, Thomas D / Pollok, Joerg M / Povey, Meical G / Poza, Alfredo Alonso / Rajgor, Amarkumar D / Rao, Jagan N / Raptis, Dimitri A / Rice, Henry E / Ridgway, Paul F / Rivas, Ana Munoz / Rodriguez-Sanjuan, Juan C / Rogers, Luke J / Da Roit, Anna / Rollett, Rebecca A / Romera, Jose L / Rooney, Siobhan M / Roxo, Vanessa I / Le Roy, Bertrand / Rubio, Eduardo E / Ruiz, Carolina Castro / Ruiz, Manuel Losada / Ryan, Éanna J / Saad, Abdel Rahman / Saeed, Samerah A / Salama, Hiba A / Salamah, Abdulrauf A / Sampietro, Gianluca M / Sarma, Diwakar R / Schaffer, Kathryn B / Schnitzbauer, Andreas A / Scurrah, Rachel J / Serevina, Olivia L / Serralheiro, Pedro A / Sewards, Joseph M / Shackcloth, Michael J / Shaw, Abigail V / Sheel, Andrea RG / Sica, Giuseppe S / De Simone, Veronica / Singh, Aminder A / Singh, Rabindra P / Skelly, Brendan L / Smith, Henry G / Sohail, Amir H / Spalding, Duncan R / Springford, Laurie R / Ssentongo, Anna E / Steinkamp, Pieter J / Stevens, Kent A / Stewart, Grant D / Stylianides, Nicholas A / Sullivan, Tom BB / Taher, Ahmed SA / Tamimy, Muhammad S / Tang, Alethea M / Tebala, Giovanni D / Tejero-Pintor, Francisco J / Thaha, Mohamed A / Thomas, Amy J / De Toma, Giorgio / La Torre, Filippo / Torres, Antonio J / Townshend, David N / Trout, Isobel M / Tucker, Sarah C / Ubhi, Harmony K / Vega, Viviana A / Velmahos, George C / Velopulos, Catherine G / Viswanath, Yirupaiahgari KS / Vivas, Alfredo A / Wade, Ryckie G / Wadley, Martin S / Wall, Joshua JS / Walters, Andrew M / Warren, Oliver J / Weerasinghe, Chamindri K / Wilkin, Richard JW / Williams, Katherine J / Winter, Stuart C / Wormald, Justin CR / Wright, Franklin L / Xyda, Souzana E / Young, Alastair L / Youssef, Mina MG / Yousuf, Farhat B / El Youzouri, Hanan / Zappa, Marco A / Abate, Emmanuele / Abdalaziz, Hossam / Abdelkarim, Mostafa / Abdou, Hossam / Aboelkassem-Ibrahim, Ahmad / Abuown, Ala / Acebes-Garcia, Fernando / Acharya, Metesh / Adamina, Michel / Addae-Boateng, Emmanuel / Aftab, Raiyyan / Agarwal, Arnav / Aguilar, José / Ahmed, Yousra / Aitken, Emma / Al-Azzawi, Marwa / Al-Embideen, Somya / Al-Masri, Mahmoud / Al-Najjar, Hani / Al-Sukaini, Ahmad / Alam, Ruhina / Alderson, Derek / Aliyeva, Zumrud / Aljanadi, Firas / Almasri, Murad / Alonso-Ortuño, Paula / Altintoprak, Fatih / Amira, Gamal / Amjad, Rabbia / Anania, Gabriele / Andabaka, Tatjana / Angelou, Dimitrios / Annamalai, Seethalakshmi / Annessi, Valerio / Anthoney, James / Anwar, Sibtain / Anwer, Mariyah / Aragon-Chamizo, Juan / Ardito, Antonella / Arigoni, Michele / Armao, Teodora / Arminio, Armando / Armstrong, Lara / Arnaud, Alexis / Asaad, Peter / Ashcroft, James / Ashmore, Christopher / Asqalan, Ahmad / Asti, Emanuele / Aubry, Emmanuelle / Aytac, Erman / Ayuso-Herrera, Esther / Baeza, Melody / Bailon-Cuadrado, Martin / Bakmaz, Bernarda / Baldi, Caterina / Baldini, Edoardo / Baldo, Stefano / Ballabio, Michele / Baloyiannis, Ioannis / Baltazar, Gerard / Bàmbina, Fabrizio / Bandiera, Alessandro / Barlow, Emma / Barmasse, Roberto / Barmpagianni, Christina / Baronio, Gianluca / Barra, Fabio / Bartsch, Anne-Marie / Basgaran, Amedra / Basha, Amr / Bashkirova, Varvara / Bastazza, Marco / Baumber, Rachel / Belcher, Elizabeth / Belvedere, Angela / Benítez-Linero, Inmaculada / Bergeat, Damien / Bernasconi, Matteo / Bhalla, Ashish / Bhutiani, Neal / Bianco, Federica / Bisagni, Pietro / Blake, Iain / Blanco-Colino, Ruth / Blazquez-Martin, Alma / Boal, Matthew / Bonavina, Luigi / Bonavina, Giulia / Bond-Smith, Giles / Booth, Karen / Borges, Filipe / Borghi, Felice / Bouchagier, Konstantinos / Bourke, Grainne / Boyle, Emily / Brachini, Gioia / Brain, Jessie / Brar, Amanpreet / Breckles, Lisa / Bretagnol, Frédéric / Brixton, Genevieve / Bruzzaniti, Placido / Bueser, Teofila / Burnside, Nathan / Caballero, Albert / Calcerrada-Alises, Enrique / Callahan, Miriam / Camarero, Enrique / Campagnaro, Tommaso / Campanelli, Michela / Candiani, Massimo / Cantalejo-Diaz, Miguel / Cao, Han / Capelli, Patrizio / Capizzi, Vita / Carcano, Giulio / Carissimi, Francesca / Carlini, Massimo / Carlucci, Michele / Carmichael, Heather / Carrasco, Milagros / Carrillo, Mariana / Carvello, Michele / Casati, Massimiliano / Castoro, Carlo / Catalan, Vanesa / Cavaleiro, Salomé / Cellerino, Paola / Centinaio, Giovanna / Cernei, Cristina / Cerro, Cristina / Cervellera, Maurizio / Chakrabortee, Sohini / Chamberlain, Stephanie / Chan, Jeffrey / Chang, Grace / Chaudhry, Dauod / Chebaro, Alexandre / Chen, David / Chetty, Govind / Chia, Zoe / Chiappini, Ambra / Chiarugi, Massimo / Chidambaram, Swathikan / Chiozza, Matteo / Cholewa, Hanna / Chong, Clara / Choolani-Bhojwani, Ekta / Christoforidis, Dimitri / Chui, Karen / Chung, Choyin / Cirillo, Bruno / Citterio, Davide / Clermidi, Pauline / Coccolini, Federico / Colletti, Gaia / Compagnoni, Bruno / Concepción-Martín, Vanesa / Confalonieri, Marco / Connolly, Hannah / Conso, Christel / Conti, Luigi / Cooper, Zara / Cordera, Fernando / Corral, Javier / Costa, Marta / Costanzi, Andrea / Cotsoglou, Christian / Cozza, Valerio / Cuming, Tamzin / Curtis, Miles / Cuschieri, Joseph / D'Agruma, Michele / D'Andrea, Giancarlo / Daliya, Prita / Dare, Oliver / Darko, Ebenezer / Day, Andrew / Dehal, Ahmed / Dehart, Dustin / Delgado-Oliver, Eduardo / Denning, Max / Desai, Anant / Desender, Liesbeth / Dester, Sara / Díaz-García, Alberto / Diaz-Peña, Patricia / Dousset, Bertrand / Doussot, Alexandre / Duchateau, Nicolas / Duff, Sarah / Dunning, Joel / Duque-Mallen, Victoria / Dziakova, Jana / Egan, Bridget / Egan, Richard / El-Ali, Abess / Elfeki, Hossam / Elhadi, Muhammed / Eljareh, Mohammed / Elkady, Ramy / Elkhafeefi, Fatimah / Elmore, Ugo / Elmoslemany, Tarek / Emmerson, Oliver / Enemosah, Ibrahim / English, Camilla / English, William / Escartin, Jorge / Estaire-Gomez, Mercedes / Evans, Luke / Evans, Jessica / Exley, Rebecca / Fabbri, Nicoló / Falco, Giuseppe / Familiari, Pietro / Fancellu, Alessandro / Farik, Shebani / Farrell, Tony / Fehervari, Matyas / Fell, Adam / Fernandez-Camuñas, Angel / Fernández-Marín, Reyes / Fernández-Martínez, María / Ferrara, Francesco / Ferrari, Guglielmo / Ferrero, Simone / Findlay, Laura / Fiore, Marco / Fiori, Enrico / Flatman, Michael / Flindall, Ian / Flor, Blas / Fontana, Tommaso / Ford, Samuel / Ford, David / Forlani, Stefano / Francone, Elisa / Frattaruolo, Colomba / Frio, Federico / Gagliano, Annalisa / Gagliardi, Filippo / Gahunia, Sukhpreet / Gaino, Francesca / Gala, Tanzeela / Galfrascoli, Elisa / Galimberti, Luca / Gallagher, Phoebe / Galleano, Raffaele / Galván-Pérez, Armando / Gammeri, Emanuele / Ganau, Mario / Garcés-García, Raúl / Garulli, Gianluca / Gascon-Ferrer, Isabel / Gattolin, Andrea / Gaujoux, Sebastien / Gentilli, Sergio / Georgiades, Fanourios / Ghanbari, Amir / Ghosh, Dhruv / Giacometti, Marco / Giblin, Anna-Victoria / Gilbert, Catherine / Giménez, Clara / Giorgakis, Emmanouil / Gipponi, Manuel / Glen, Paul / Goatly, Giles / Gobatti, Davide / Godbole, Chintamani / Gohil, Kajal / Gómez, Marcos / Gomez-Rosado, Juan-Carlos / Gonullu, Emre / Gonzalez-Gonzalez, Enrique / Gordini, Luca / Gracia, Isabel / Gracia-Roche, Carlos / Granieri, Stefano / Green, Susanna / Grivon, Manuela / Grove, Thomas / Guaglio, Marcello / Guaitoli, Eleonora / Guglielmi, Alfredo / Guha, Soumya / Gustavino, Claudio / Habeeb, Amir / Hagger, Robert / Hakmi, Hazim / Halkias, Constantine / Hall, Claire / Hampton, Matthew / Handa, Siddhartha / Hansen, Laura / Haq, Iram / Harky, Amer / Harries, Rhiannon / Harrison, Joseph / Hasan, Raashad / Hawari, Mohammad / Hawkin, Paul / Hebblethwaite, Bethany / Henriques, Susana / Heritage, Emily / Hernandez-Juara, Pilar / Herrero-Lopez, Maria / Hervieux, Erik / Heyd, Bruno / Higgs, Simon / Hitchman, Louise / Ho, Beatrice / Hogan, Aisling / Hölzle, Frank / Hossain, Tanvir / Hurt, Libor / Hutchinson, Peter / Iacob, Giulio / Iannone, Immacolata / Ibrahim, Sherif / Iovino, Domenico / Isik, Arda / Jafarova, Sevda / Jamil, Tahir / Jayaraju, Ullas / Jenner, Edward / Jimenez-Higuera, Elisa / Jimeno, Jaime / Jones, Mark / Judkins, Nicholas / Kalavrezos, Nicholas / Kalidindi, Venugopala / Kalkat, Maninder / Kamal, Mona / Kamphues, Carsten / Kang, Chong / Kara, Yasin / Karam, Edward / Karim, Ahmed / Kashora, Florence / Kearney, David / Khajuria, Apoorva / Khan, Umul / Khan, Azam / Khatri, Chetan / Kinnaman, Gabriel / Kinross, James / Kler, Aaron / Klimopoulos, Serafeim / Kocataş, Ali / Kolias, Angelos / Königsrainer, Alfred / Konsten, Joop / Kontovounisios, Christos / Kourdouli, Amar / Krishnan, Emily / Kristinsson, Sverrir / Kruijff, Schelto / Kudsk-Iversen, Søren / Kufeji, Dorothy / Kugler, Nadav / Kulkarni, Rugved / Kurihara, Hayato / Laface, Letizia / Lakkis, Zaher / Lami, Mariam / Landaluce-Olavarria, Aitor / Lapolla, Pierfrancesco / Lawani, Ismail / Lawday, Samuel / Lázaro, André / Lecolle, Katia / Leventoglu, Sezai / Li, Zoe / Liew, Ignatius / Lisi, Giorgio / Lizzi, Vincenzo / Lo, Terence / Lomiento, Daniele / Longhi, Marco / Lostis, Emilie / Lostoridis, Eftychios / Loubani, Mahmoud / Lowy-Benoliel, Alejandro / Lucianetti, Alessandro / Luke, Louis / Lunevicius, Raimundas / Luraghi, Marco / Lye, George / Mabrouk, Islam / Macchi, Alberto / MacDonald, Luisa / Machairas, Nikolaos / Madonini, Marco / Magowan, Drew / Maisonneuve, Emeline / Majkowska, Agata / Majkowski, Lawrence / Mak, Jason / Malabarba, Stefano / Malerba, Michele / Mannan, Syed / Manson, Joanna / Mansuri, Ahmer / Mantoglu, Baris / Manu, Nichola / Maqsood, Afnan / Marano, Alessandra / Marchbank, Adrian / Marcos-Santos, Pablo / Marrano, Enrico / Martin, Janet / Martin, Emmeline / Martin, Guy / Martin-Albo, Lorena / Martín-Román, Lorena / Martinelli, Fabio / Martínez-dePaz, Fernando / Martinez-German, Antonio / Martinez-Pinedo, Carlos / Martins, Ricardo / Marwan, Hisham / Marzi, Federica / Mathieu, Pierre / Matute-Najarro, Maria-Soledad / Maw, Andrew / Mazingi, Dennis / Mazzaferro, Vincenzo / McCanny, Andrew / McKenzie, Katherine / McLarty, Nicola / McPherson, Iain / Medina, Esther / Mediratta, Saniya / Medone, Marzia / Mehra, Gautam / Mele, Simone / Melero-Cortés, Lidia / Mendoza-Moreno, Fernando / Meneghini, Simona / Mercante, Giuseppe / Merdrignac, Aude / Merola, Stephen / Metallidis, Symeon / Michel, Martin / Migliore, Marco / Mihanovic, Jakov / Miller, Douglas / Mingoli, Andrea / Minto, Gary / Mirabella, Antonello / Misra, Nikhil / Mitrasinovic, Stefan / Miu, Victor / Moawad, Nader / Mochet, Sylvie / Modabber, Ali / Mohammad, Adam / Mohan, Midhun / Moliner-Sánchez, Carmen / Mongelli, Francesco / Monteleone, Michela / Montuori, Mauro / Moore, Rachel / Mora-Guzmán, Ismael / Morales, Xavier / Morales, Dieter / Morelli, Luca / Morelli, Lucia / Morgan, Richard / Morris, Chris / Mortini, Pietro / Mosca, Angelo / Motter, Dema / Moug, Susan / Mukherjee, Samrat / Najdy, Manhal / Nakas, Apostolos / Namazov, Ilgar / Naredla, Pradyumna / Nasef, Emmhamed / Nassa, Heeam / Nath, Rahul / Navarro-Sánchez, Antonio / Nazarian, Scarlet / Negri, Giampiero / Nehra, Deepika / Neil-Dwyer, Jason / Neri, Jacopo / Newton, Katy / Nikaj, Herald / Niquen, Milagros / Nobile, Sara / Nogueiro, Jorge / Ntirenganya, Faustin / Nugent, Michael / Núñez, Jordi / Ocaña, Juan / Okechukwu, Valentine / Oliva-Mompean, Fernando / Oliveira, Ana / Ollat, Didier / Onos, Lavinia / Osagie-Clouard, Liza / Osman, Khabab / Ottolina, Jessica / Ourieff, Jared / Outani, Oumaima / Oyewole, Bankole / Ozben, Volkan / Pacheco-Sanchez, David / Padilla-Valverde, David / Pai, Madhava / Paiella, Salvatore / Paisley, Samuel / Palini, Gianmarco / Palmeri, Matteo / Panahi, Pedram / Parente, Alessandro / Parlanti, Daniele / Parmar, Chetan / Pascual, Angela / Patel, Mahul / Pathak, Abhijit / Patil, Sangram / Pattyn, Piet / Peckham-Cooper, Adam / Pedrazzani, Corrado / Pellino, Gianluca / Peluso, Chiara / Pereira, André / Pereira-Neves, António / Perez-Diaz, Md / Pérez-González, Marta / Pérez-Saborido, Baltasar / Perivoliotis, Konstantinos / Perkins, Clare / Peros, Georgios / Perotto, Ornella / Perra, Teresa / Petrone, Patrizio / Phenix, George / Picazo, Sara / Picon-Rodriguez, Rafael / Piloni, Martina / Pingarrón-Martín, Lorena / Pinotti, Enrico / Pisanu, Adolfo / Pizzini, Paolo / Pockney, Peter / Podda, Mauro / Podolsky, Dina / Poggioli, Gilberto / Pompili, Cecilia / Pontari, Michael / Porcu, Alberto / Potter, Ryan / Price, Claire / Pruvot, François-René / Pujol-Muncunill, Roger / Puppo, Andrea / Quante, Markus / Quintana-Villamandos, Begoña / Qureshi, Ali / Radenkovic, Dejan / Rakvin, Ivan / Ramallo-Solís, Irene / Ramcharan, Sean / Ramos, Diego / Ramos-Bonilla, Antonio / Ramzi, Joussi / Rathinam, Sridhar / Rausa, Emanuele / Ravaioli, Matteo / Ravindran, Sharanya / Raymond, Thomas / Razik, Aisha / Redfern, Jennifer / Reguera-Rosal, Julio / Rela, Mariam / Rey-Biel, Juan / Rey-Valcarcel, Cristina / Ribolla, Marta / Richards, Tomos / Richmond, Michael / Righini, Erminio / Rio-Gomez, Javier / Riyat, Harjoat / Rizvi, Sana / Roberts, Keith / Roberts, Matthew / Robertson, Stuart / Robertson, Ronald / Robin-Valle, Alvaro / Rochon, Melissa / Rojo, Mikel / Rolli, Luigi / Romano, Silvio / Ross, Elizabeth / Ross, Howard / Rossborough, Catherine / Rottoli, Matteo / Ruiz-Grande, Fernando / Ruiz-Martin, Irene / Ruiz-Soriano, María / Ruzzenente, Andrea / Ryska, Ondrej / Saez, Carlos / Sagnotta, Andrea / Sahnan, Kapil / Sahni, Arun / Salim, Ali / Sallam, Ibrahim / Salvia, Roberto / Samadov, Elgun / Sammarco, Giuseppe / Sampaio-Alves, Mafalda / Sánchez-Arteaga, Alejandro / Sanchez-Fuentes, Maria-Nieves / Sanchez-Pelaez, Daniel / Sanchez-Perez, Coral / Sanchez-Rubio, Maria / Sancho-Muriel, Jorge / Sanders, Julie / Santero-Ramirez, Maria-Pilar / Santora, Thomas / Santoro, Antonio / Santos, Irene / Santos-Sousa, Hugo / Sapienza, Paolo / Sartarelli, Lodovico / Sarveswaran, Janahan / Sasia, Diego / Saudemont, Alain / Saudi-Moro, Sef / Saxena, Shobhit / Saxena, Dolly / Sayasneh, Ahmad / Scalabre, Aurelien / Schache, Andrew / Schiavina, Riccardo / Schineis, Christian / Schreckenbach, Teresa / Scorza, Antonella / Scott, Lucy / Seegert, Sara / Seguin-Givelet, Agathe / Senent-Boza, Ana / Seymour, Keith / Shabana, Amanda / Shah, Karishma / Shah, Jigar / Shah, Preena / Shah, Sujay / Shakir, Taner / Shalaby, Mostafa / Shankar, Sushma / Shaw, Richard / Shehata, Sameh / Shenfine, Amy / Sheridan, Kelda / Sherief, Ahmed / Sherief, Mohamed / Sherif, Mohamed / Shinkwin, Michael / Shu, Sebastian / Siaw-Acheampong, Kwabena / Sileri, Pierpaolo / Singh, Abhinav / Singh, Shailendra / Sinha, Sanjay / Sinha, Deepti / Siragusa, Leandro / Sivaprakasam, Rajesh / Sivayoganathan, Sriharan / Smillie, Robert / Smith, Claire / Smith, Andrew / Smith, Christopher / Sochorova, Dana / Soggiu, Fiammetta / Sohrabi, Catrin / Solari, Francesca / Solli, Piergiorgio / Soreide, Kjetil / Spinelli, Antonino / Spoletini, Domenico / Spriano, Giuseppe / Sravanam, Sanskrithi / Ssentongo, Paddy / Stanger, Sophie / Stavroulias, Dionisios / Steel, Ben / Stella, Marco / Stewart, Robbie / Stringer, Sally / Sulen, Nina / Sundar, Sudha / Sundhu, Matthew / Suri, Avni / Syed, Arooj / Szatmary, Peter / Tabiri, Stephen / Tadross, Daniel / Taglietti, Lucio / Tansey, Rosamond / Tartaglia, Dario / Tawheed, Ahmed / Tayeh, Salim / Teles, Tobias / Testa, Valentina / Tewari, Nilanjana / Thoenissen, Philipp / Thomas, Kane / Thomin, Anne / Thrush, Jessica / Tierney, Sean / Tiwari, Abhinav / Toh, Simon / Toledo, Enrique / Tonini, Valeria / Torkington, Jared / Torquati, Alfonso / Torzilli, Guido / Totty, Joshua / Tourountzi, Paraskevi / Tousidonis, Manuel / Townend, Philip / Townsend, Catherine / Trompeter, Alex / Trotta, Francesco / Truant, Stéphanie / Trujillo-Díaz, Jeancarlos / Tsoulfas, Georgios / Turco, Celia / Turrado-Rodriguez, Victor / Turri, Giulia / Tustin, Harry / Tyler, Jayne / Tzedakis, Stylianos / Tzovaras, George / Uittenbogaart, Martine / Ullah, Ramzan / Urban, Shane / Urbani, Alessia / Usai, Antonella / Vaccarella, Gianpaolo / Valdes-Hernandez, Javier / Valsecchi, Luca / Vashisht, Rajiv / Vázquez-Fernández, Andrea / Venn, Mary / Vera-Mansilla, Cristina / Vergari, Roberto / Vescio, Giuseppina / Vidya, Raghavan / Vieira, Paula / Vijay, Vardhini / Vimalachandran, Dale / Violante, Tommaso / Volpe, Anita / Vovola, Fernanda / Vulliamy, Paul / Wall, Rosemary / Wallwork, Kate / Ward, Alex / Warwick, David / Waseem, Saima / Weaver, Helen / Wells, Fiona / Wen, Jiaxin / West, Raha / Whitehall, Emma / Wild, Laura / Wilkins, Alex / Williams, Gethin / Williams, Matthew / Winnand, Philipp / Wong, Ken / Worku, Dawit / Wright, Naomi / Yalamanchili, Seema / Yershov, Danylo / Yildiz, Alp / Young, Richard / Yurttas, Can / Zadegan, Frederic / Zafar, Noman / Zakaria, Rasheed / Zambon, Martina / Zanini, Nicola / Zarate, Alba / Zerbib, Philippe / Zizzo, Maurizio / Zmora, Oded / Zonta, Sandro / van Berge Henegouwen, Mark I / van der Plas, Willemijn Y / Ali, Inthekab Ali Mohamed / Bakri, Nur Amalina Che / Bauset, Juan Carlos Catalá / Abou Chaar, Mohamad K / Marino Cosentino, Luigi MP / Gómez Díaz, Carlos J / Garcia Galocha, Jose L / de Gheldere, Charles A / Ataíde Gomes, Gustavo Mendonça / Beltrán de Heredia, Juan / Blazer III, Dan G / Nugent III, William C / Ali karar, Ali A / Borja De Lacy, F / Blas Laina, Juan luis / Shane Lester, Madan Jha / Liyanage, Aloka S D / Al Maadany, Faraj S / De Marchi, Joshua A / Ramos-De la Medina, Antonio / Mithany, Reda H M / Sanchez del Pueblo, Cristina / van Ramshorst, Gabrielle H / De Salas, Maria Marqueta / De Souza, Anthony C / Dolores Del Toro, M / Archer, James E / Odeh, Abdulrahman / Erridge, Simon / Salem, Hosni Khairy / Jones, Gareth P / Gardner, Anne / Tripathi, Shiva S / Gregg, Anne / Jeganathan, Reuben / Siddique, Muhammad Harris / Lombardi, Celestino P / Martin, Benjamin / Leo, Cosimo Alex / Dass, Debashis / Di Franco, Gregorio / Jiao, Long R / Mari, Giulio Maria / Capitan-Morales, Luis-Cristobal / Connelly, Tara M / Alanbuki, Ammar / De Virgilio, Armando / Schilling, Clare / San Miguel Mendez, Carlos / Kulkarni, Gauri / Nizami, Kulsoom / Walsh, Stewart / Dean, Harry / Ruiz-Marin, Miguel / Houston, Rory / Trompetto, Mario / Chrastek, David / Kouritas, Vasileios / Cannoletta, Maria / Rosato, Francesco / Kaushal, Manish V / Costa, Paulo Matos / Elkadi, Hannah H / Johnstone, Jack R / Irvine, Esmee / Alvarez, Maria R / Corbellini, Carlo / Venkatesan, Gowtham S / Mateo-Sierra, Olga / Martínez-Pérez, Carolina / Serrano González, Javier / Hernández Bartolomé, Miguel Ángel / Díaz Pérez, David / Gutiérrez Samaniego, María / Galindo Jara, Pablo / Sharma, Neil / Smart, Neil J / Keller, Deborah S

an international cohort study

2020

Abstract: Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

Abstract	Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection.Methods This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation.Findings This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74.0%) had emergency surgery and 280 (24.8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26.1%) patients. 30-day mortality was 23.8% (268 of 1128). Pulmonary complications occurred in 577 (51.2%) of 1128 patients; 30-day mortality in these patients was 38.0% (219 of 577), accounting for 81.7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1.75 [95% CI 1.28-2.40], p<0.0001), age 70 years or older versus younger than 70 years (2.30 [1.65-3.22], p<0.0001), American Society of Anesthesiologists grades 3-5 versus grades 1-2 (2.35 [1.57-3.53], p<0.0001), malignant versus benign or obstetric diagnosis (1.55 [1.01-2.39], p=0.046), emergency versus elective surgery (1.67 [1.06-2.63], p=0.026), and major versus minor surgery (1.52 [1.01-2.31], p=0.047).Interpretation Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery.
Keywords	Adult ; covid19
Subject code	616 ; 610
Language	English
Publishing country	it
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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