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  1. Article ; Online: Postural hypotension.

    Gilani, Artaza / Juraschek, Stephen P / Belanger, Matthew J / Vowles, Julie E / Wannamethee, S Goya

    BMJ (Clinical research ed.)

    2021  Volume 373, Page(s) n922

    MeSH term(s) Blood Pressure ; Blood Pressure Determination ; Diagnosis, Differential ; Dizziness/etiology ; Humans ; Hypotension, Orthostatic/complications ; Hypotension, Orthostatic/diagnosis ; Hypotension, Orthostatic/therapy
    Language English
    Publishing date 2021-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.n922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Novel Conservative Approach to High Surgical Risk Frail Proximal Femur Fractures.

    Koizia, Alexander / Abuown, Ala / Vowles, Julie / Smith, Damien / Koizia, Louis J

    Case reports in orthopedics

    2020  Volume 2020, Page(s) 8847080

    Abstract: One of the major impacts following a neck of femur fracture is pain. Most patients (nearly all) undergo an operation. This usually includes the frailest terminal patients and deemed a palliative procedure to reduce ongoing pain. The operation comes with ... ...

    Abstract One of the major impacts following a neck of femur fracture is pain. Most patients (nearly all) undergo an operation. This usually includes the frailest terminal patients and deemed a palliative procedure to reduce ongoing pain. The operation comes with risks and can reduce life expectancy in these patients and result in prolonged hospital admission, delirium, and postoperative complications. This case highlights a novel approach to managing the frailest end-of-life patients that does not require them to undergo a conventional operation. The case resulted in a quick discharge from hospital and for the patient and family to maximise the time out of hospital, with a reduced analgesic burden and a peaceful passing away. We feel that this could be an alternative, more humane option for such patients.
    Language English
    Publishing date 2020-06-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2684648-2
    ISSN 2090-6757 ; 2090-6749
    ISSN (online) 2090-6757
    ISSN 2090-6749
    DOI 10.1155/2020/8847080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Trial results of a new combination therapy for myeloid leukaemia.

    Leach, Sue / Richardson, Carol / Vowles, Julie K / Charlton, Lindsey

    Nursing times

    2002  Volume 98, Issue 29, Page(s) 32–34

    Abstract: Chronic myeloid leukaemia is a condition that affects around 600 people a year in the UK. The only curative intervention to date has been bone-marrow transplantation. A combined drug therapy featuring interferon and a new drug called imatinib has shown ... ...

    Abstract Chronic myeloid leukaemia is a condition that affects around 600 people a year in the UK. The only curative intervention to date has been bone-marrow transplantation. A combined drug therapy featuring interferon and a new drug called imatinib has shown encouraging results in recent trials. In one trial of 532 patients, 60% achieved a major cytogenetic response, while in 41% no leukaemia could be detected using normal cytogenetic techniques. This article provides background on the nature of chronic myeloid leukaemia, and discusses the imatinib trial results and indications for future treatments.
    MeSH term(s) Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Benzamides ; Clinical Trials as Topic ; Humans ; Imatinib Mesylate ; Interferons/administration & dosage ; Interferons/therapeutic use ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Piperazines/administration & dosage ; Piperazines/therapeutic use ; Pyrimidines/administration & dosage ; Pyrimidines/therapeutic use
    Chemical Substances Antineoplastic Agents ; Benzamides ; Piperazines ; Pyrimidines ; Imatinib Mesylate (8A1O1M485B) ; Interferons (9008-11-1)
    Language English
    Publishing date 2002-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 391202-4
    ISSN 0954-7762 ; 0029-6589
    ISSN 0954-7762 ; 0029-6589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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