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  1. Book ; Thesis: Experimental approaches towards non-responsiveness in allo- and xenotransplantation

    Vriens, Patrick Wilhelmus Henri Erik

    2000  

    Author's details door Patrick Wilhelmus Henri Erik Vriens
    Language English ; Dutch
    Size 207 S. : Ill., graph. Darst.
    Publisher Pasmas B.V
    Publishing place Den Haag
    Publishing country Netherlands
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Leiden, Univ., Diss., 2000
    Note Zsfassung in niederländ. Sprache
    HBZ-ID HT013420239
    ISBN 90-9014240-1 ; 978-90-9014240-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2002 E 3221 order for loan Magazin

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  2. Article ; Online: Protocol for a prospective, longitudinal cohort study on the effect of arterial disease level on the outcomes of supervised exercise in intermittent claudication: the ELECT Registry.

    van den Houten, Marijn Ml / Jansen, Sandra Cp / Sinnige, Anneroos / van der Laan, Lijckle / Vriens, Patrick Whe / Willigendael, Edith M / Lardenoije, Jan-Willem Hp / Elshof, Jan-Willem M / van Hattum, Eline S / Lijkwan, Maarten A / Nyklíček, Ivan / Rouwet, Ellen V / Koelemay, Mark Jw / Scheltinga, Marc Rm / Teijink, Joep Aw

    BMJ open

    2019  Volume 9, Issue 2, Page(s) e025419

    Abstract: Introduction: Despite guideline recommendations advocating conservative management before invasive treatment in intermittent claudication, early revascularisation remains widespread in patients with favourable anatomy. The aim of the Effect of Disease ... ...

    Abstract Introduction: Despite guideline recommendations advocating conservative management before invasive treatment in intermittent claudication, early revascularisation remains widespread in patients with favourable anatomy. The aim of the Effect of Disease Level on Outcomes of Supervised Exercise in Intermittent Claudication Registry is to determine the effect of the location of stenosis on the outcomes of supervised exercise in patients with intermittent claudication due to peripheral arterial disease.
    Methods and analysis: This multicentre prospective cohort study aims to enrol 320 patients in 10 vascular centres across the Netherlands. All patients diagnosed with intermittent claudication (peripheral arterial disease: Fontaine II/Rutherford 1-3), who are considered candidates for supervised exercise therapy by their own physicians are appropriate to participate. Participants will receive standard care, meaning supervised exercise therapy first, with endovascular or open revascularisation in case of insufficient effect (at the discretion of patient and vascular surgeon). For the primary objectives, patients are grouped according to anatomical characteristics of disease (aortoiliac, femoropopliteal or multilevel disease) as apparent on the preferred imaging modality in the participating centre (either duplex, CT angiography or magnetic resonance angiography). Changes in walking performance (treadmill tests, 6 min walk test) and quality of life (QoL; Vascular QoL Questionnaire-6, WHO QoL Questionnaire-Bref) will be compared between groups, after multivariate adjustment for possible confounders. Freedom from revascularisation and major adverse cardiovascular disease events, and attainment of the treatment goal between anatomical groups will be compared using Kaplan-Meier survival curves.
    Ethics and dissemination: This study has been exempted from formal medical ethical approval by the Medical Research Ethics Committees United 'MEC-U' (W17.071). Results are intended for publication in peer-reviewed journals and for presentation to stakeholders nationally and internationally.
    Trial registration number: NTR7332; Pre-results.
    MeSH term(s) Carotid Artery Diseases ; Combined Modality Therapy ; Constriction, Pathologic/pathology ; Exercise Therapy/methods ; Humans ; Intermittent Claudication/therapy ; Longitudinal Studies ; Multicenter Studies as Topic ; Netherlands ; Peripheral Arterial Disease/pathology ; Prospective Studies ; Quality of Life ; Registries ; Research Design ; Treatment Outcome ; Vascular Surgical Procedures ; Walk Test
    Language English
    Publishing date 2019-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2747269-3
    ISSN 2044-6055 ; 2044-6055 ; 2053-3624
    ISSN (online) 2044-6055
    ISSN 2044-6055 ; 2053-3624
    DOI 10.1136/bmjopen-2018-025419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Tilburg double blind randomised controlled trial comparing inguinal hernia repair according to Lichtenstein and the transinguinal preperitoneal technique

    Gerritsen Pieter G / Verhofstad Michiel HJ / Oostvogel Henk JM / de Schipper Hans JP / Koning Giel G / van Laarhoven Kees CJHM / Vriens Patrick WHE

    Trials, Vol 10, Iss 1, p

    2009  Volume 89

    Abstract: Abstract Background Anterior open treatment of the inguinal hernia with a tension free mesh has reduced the incidence of recurrence and direct postoperative pain. The Lichtenstein procedure rules nowadays as reference technique for hernia treatment. Not ... ...

    Abstract Abstract Background Anterior open treatment of the inguinal hernia with a tension free mesh has reduced the incidence of recurrence and direct postoperative pain. The Lichtenstein procedure rules nowadays as reference technique for hernia treatment. Not recurrences but chronic pain is the main postoperative complication in inguinal hernia repair after Lichtenstein's technique. Preliminary experiences with a soft mesh placed in the preperitoneal space showed good results and less chronic pain. Methods The TULIP is a double-blind randomised controlled trial in which 300 patients will be randomly allocated to anterior inguinal hernia repair according to Lichtenstein or the transinguinal preperitoneal technique with soft mesh. All unilateral primary inguinal hernia patients eligible for operation who meet inclusion criteria will be invited to participate in this trial. The primary endpoint will be direct postoperative- and chronic pain. Secondary endpoints are operation time, postoperative complications, hospital stay, costs, return to daily activities (e.g. work) and recurrence. Both groups will be evaluated. Success rate of hernia repair and complications will be measured as safeguard for quality. To demonstrate that inguinal hernia repair according to the transinguinal preperitoneal (TIPP) technique reduces postoperative pain to <10%, with α = 0,05 and power 80%, a total sample size of 300 patients was calculated. Discussion The TULIP trial is aimed to show a reduction in postoperative chronic pain after anterior hernia repair according to the transinguinal preperitoneal (TIPP) technique, compared to Lichtenstein. In our hypothesis the TIPP technique reduces chronic pain compared to Lichtenstein. Trial registration ISRCTN 93798494
    Keywords Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2009-09-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article ; Online: Perioperative SARS-CoV-2 infections increase mortality, pulmonary complications, and thromboembolic events

    Jonker, Pascal K.C. / van der Plas, Willemijn Y. / Steinkamp, Pieter J. / Poelstra, Ralph / Emous, Marloes / van der Meij, Wout / Thunnissen, Floris / Bierman, Wouter F.W. / Struys, Michel M.R.F. / de Reuver, Philip R. / de Vries, Jean-Paul P.M. / Kruijff, Schelto / Boerma, Djamilla / Gerritsen, Sarah L. / van Petersen, André S. / Stevens, Charles T. / van Sambeek, Marc / Hölscher, Marleen / Pronk, Apollo /
    Bakker, Wouter J. / Vriens, Patrick Whe / Houwen, Thymen / Wegdam, Johannes A. / de Vries Reilingh, Tammo S. / Schipper, Ellis / Teeuwen, Pascal HE. / van Ginhoven, Tessa M. / Viëtor, Charlotte / van der Oest, Mark JW. / Gans, Sarah / van Duijvendijk, Peter / Herklots, Tanneke / de Hoop, Tom / de Graaff, Michelle / Sloothaak, Didi / Bolster - van Eenennaam, Marieke / Baaij, Jedidja / Vermaas, Maarten / Voigt, Kelly R. / Patijn, Gijs A. / Bransma, Amarins TA. / Leclercq, Wouter KG. / Sijmons, Julie ML. / Uittenbogaart, Martine / Verheijen, Paul M. / Burghgraef, Thijs A. / Teunissen, Manon / Frima, Herman / Bachiri, Said / Groen, Lennaert CB. / Thunissen, Floris M. / Vermeulen, Britt AM. / Groen, Anna / van Eekeren, Ramon RJP. / Spillenaar Bilgen, Ernst J. / Harlaar, Niels J. / Jonker, Fredrik HW. / van der Burg, Sjirk W. / Posma-Bouman, Lisanne AE. / Oosterling, Steven J. / Franken, Josephine / Nellensteijn, David R. / Bensi, Elena Argia Bianca / van den Broek, Wim / Hendriks, Eduard R. / van Geloven, Anna AW. / Jonker, Pascal KC. / Bierman, Wouter FW. / Struys, Michel MRF. / Janssen, Yester F. / van Dam, Gooitzen M. / IJpma, Frank FA. / van der Riet, Claire / Feitsma, Eline / Ma, Kirsten / Kleiss, Simone / Richir, Milan C. / Vriens, Menno R. / Filipe, Mando D. / den Boer, Frank C. / Dekker, Nicole AM. / Verhagen, Tim / ter Brugge, Floor / Lagae, Emmanuel AGL. / Boerma, Evert-Jan G. / Schweitzer, Donald / Keulen, Mark HF. / Ketting, Shirley

    Surgery ; ISSN 0039-6060

    A Dutch, multicenter, matched-cohort clinical study

    2020  

    Keywords Surgery ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.surg.2020.09.022
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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