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Article ; Online: D-dimer levels and acute pulmonary embolism development in COVID-19 patients

Vural Ahmet / Kahraman Ahmet Nedim

Journal of Mind and Medical Sciences, Vol 8, Iss 1, Pp 133-

2021 Volume 138

Abstract: Objective. To identify those who develop pulmonary embolism with Ddimer levels by evaluating pulmonary CT angiographies of patients who are followed up with suspicion of coronavirus disease 2019 (COVID-19). Methods. Patients who were followed up in a ... ...

Abstract	Objective. To identify those who develop pulmonary embolism with Ddimer levels by evaluating pulmonary CT angiographies of patients who are followed up with suspicion of coronavirus disease 2019 (COVID-19). Methods. Patients who were followed up in a community hospital with suspicion of COVID-19 and underwent Pulmonary CT angiography examination were evaluated. Clinical and demographic parameters and DDimer values for patients with and without pulmonary embolism were evaluated in the pulmonary CT angiogram. Results. During the COVID-19 pandemic, Thorax CT examination was performed in our center for suspicion or follow-up of COVID-19 infection in 3396 patients. Pulmonary CT angiography was applied to 312 (9.2%) of these cases. Of these 312 patients, 141 were identified as COVID-19 patients. Acute pulmonary embolism was detected in 33 (23.4%) of 141 patients with COVID-19 and pulmonary CT angiogram. D-dimer levels (5964.97±4036.8 μg/L) of patients with COVID-19 infection and pulmonary embolism were significantly higher than D-dimer levels (972.4±1766.8 μg/L) of patients without pulmonary embolism. In patients with COVID-19 infection, a Ddimer value higher than 1013 μg/L was determined as a cut-off value with 100% sensitivity for the presence of pulmonary embolism. Conclusions. For those struggling with the COVID-19 pandemic, pulmonary embolism should be kept in mind if D-dimer values increase more than expected in the presence of respiratory distress that Thorax CT findings cannot explain.
Keywords	pulmonary embolism ; covid-19 ; pulmonary ct angiography ; d-dimer ; Medicine (General) ; R5-920
Subject code	610 ; 616
Language	English
Publishing date	2021-04-01T00:00:00Z
Publisher	Ion Motofei, Carol Davila University
Document type	Article ; Online
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Article ; Online: Added value of coronal-T1W sequence to the lumbar MR imaging protocol for low back pain.

Kahraman, Ahmet Nedim / Vural, Ahmet

Biomedica : revista del Instituto Nacional de Salud

2022 Volume 42, Issue Sp. 1, Page(s) 33–40

Abstract: Introduction: Magnetic resonance imaging (MRI) is the most appropriate imaging method to investigate low back pain. As low back pain is very common, a large number of MRI scans are performed.: Objective: To evaluate the extraspinal findings and ... ...

Title translation	Valor de la secuencia coronal-T1W agregada al protocolo de imágenes de resonancia magnética en casos de dolor lumbar
Abstract	Introduction: Magnetic resonance imaging (MRI) is the most appropriate imaging method to investigate low back pain. As low back pain is very common, a large number of MRI scans are performed. Objective: To evaluate the extraspinal findings and clinical effect of the T1-weighted spin echo (T1W SE) coronal sequence added to the lumbar MRI protocol for low back pain. Materials and methods: In 2015, we added a T1-weighted (T1W) coronal sequence to our routine lumbar MRI protocol. We retrospectively evaluated 969 lumbar MRI images for low back pain performed with this protocol. The extraspinal MRI findings obtained from them were then grouped as associated with low back pain (Category 1) and not associated with low back pain (Category 2). We also evaluated whether the recorded incidental extraspinal findings could be detected on conventional sagittal and axial images. Results: Ninety-six (63%) of the extraspinal findings were associated with low back pain (Category 1) and 56 (37%), Category 2. Seventy-eight percent of the extraspinal findings were detected only on coronal-T1W images and not on conventional images. Conclusion: Adding coronal-T1W sequence to the routine protocol of lumbar MRI can help to identify extraspinal findings and guide clinical treatment.
MeSH term(s)	Humans ; Low Back Pain/diagnostic imaging ; Low Back Pain/pathology ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/pathology ; Magnetic Resonance Imaging/methods ; Retrospective Studies
Language	Spanish
Publishing date	2022-05-01
Publishing country	Colombia
Document type	Journal Article
ZDB-ID	2059952-3
ISSN	2590-7379 ; 0120-4157
ISSN (online)	2590-7379
ISSN	0120-4157
DOI	10.7705/biomedica.5845
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Article: Response to "Pulmonary fibrotic-like changes in patients recovering from COVID-19: Correspondence".

Vural, Ahmet / Kahraman, Ahmet Nedim

Tuberkuloz ve toraks

2022 Volume 70, Issue 1, Page(s) 112

Language	English
Publishing date	2022-03-31
Publishing country	Turkey
Document type	Letter ; Comment
ZDB-ID	2468802-2
ISSN	0494-1373
ISSN	0494-1373
DOI	10.5578/tt.20229916
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Article ; Online: Evaluation of common carotid artery wall stiffness by shear wave elastography in smokers and non-smokers.

Goksu, Kamber / Vural, Ahmet / Kahraman, Ahmet N / Aslan, Isil K

Tobacco induced diseases

2024 Volume 22

Abstract: Introduction: Smoking is one of the most important preventable causes of cardiovascular diseases. Vascular disease caused by smoking is associated with vascular endothelial damage, platelet aggregation, and adhesion. In our study, we examined the effect ...

Abstract	Introduction: Smoking is one of the most important preventable causes of cardiovascular diseases. Vascular disease caused by smoking is associated with vascular endothelial damage, platelet aggregation, and adhesion. In our study, we examined the effect of chronic smoking on vessel wall stiffness in smokers and control group by measuring carotid artery wall stiffness by shear wave ultrasonography. Methods: Sixty-two smokers of similar ages and genders, and 67 people who never smoked in the last ten years were included as the control group in this cross-sectional study. Arterial wall stiffness over the common carotid arteries of all participants was measured by shear wave elastography (SWE). In addition, each patient's blood pressure, fasting blood glucose, body mass index (BMI), HDL and LDL cholesterol measurements were recorded. Results: Arterial wall stiffness values in smokers were found to be statistically significantly higher than in non-smokers. The mean of SWE measurements of the smokers was 47.3 ± 6.2 kPa, and that of the control group was 42.9 ± 4 kPa. The mean values of HDL and LDL of the smokers were 46.9 ± 5.6 mg/dL and 147.3 ± 9.3 mg/dL, respectively, and those of the control group were 50.3 ± 5.1 mg/dL and 136.9 ± 5.9 mg/dL. The LDL cholesterol values were statistically significantly higher in smokers compared to the control group, and HDL cholesterol values were statistically significantly lower in smokers. Conclusions: In our study, the arterial wall stiffness values measured by the SWE technique were higher in smokers than non-smokers.
Language	English
Publishing date	2024-03-08
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2194616-4
ISSN	1617-9625 ; 1617-9625
ISSN (online)	1617-9625
ISSN	1617-9625
DOI	10.18332/tid/185300
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Article ; Online: Predictors of the right ventricular perforation caused by active-fixation pacing and defibrillator leads: A single-centre experience.

Celikyurt, Umut / Acar, Burak / Yavuz, Sadan / Agacdiken, Aysen / Vural, Ahmet

Journal of cardiovascular electrophysiology

2024 Volume 35, Issue 3, Page(s) 399–405

Abstract: Introduction: Active-fixation leads have been associated with higher incidence of cardiac perforation. Large series specifically evaluating radiographic predictors of right ventricular (RV) lead perforation are lacking.: Methods: We conducted a ... ...

Abstract	Introduction: Active-fixation leads have been associated with higher incidence of cardiac perforation. Large series specifically evaluating radiographic predictors of right ventricular (RV) lead perforation are lacking. Methods: We conducted a retrospective observational study including 1691 consecutive patients implanted with an active fixation pacing and defibrillator lead at our institution between January 2015 and January 2021. Fourteen patients who had clinically relevant RV perforation caused by pacemaker and implantable cardioverter-defibrillator leads were included in the study. Results: Univariate and multivariate analyses were used to identify predictors of RV perforation. In multivariate analysis, lead slack score (odds ratio [OR]: 3.694, 95% confidence interval [CI]: 1.066-12.807; p = .039), change in lead slack height (OR: 1.218, 95% CI: 1.011-1.467; p = .038) and width (OR: 1.253, 95% CI: 1.120-1.402; p = .001), left ventricular ejection fraction (OR: 0.995, 95% CI: 0.910-1.088; p = .032) were independent predictors of RV perforation. Conclusion: Fluoroscopic predictors of RV perforation associated with RV lead can be easily determined during implantation. Identification of these predictors may prevent the sequelae of RV perforation associated with active-fixation leads.
MeSH term(s)	Humans ; Stroke Volume ; Ventricular Function, Left ; Pacemaker, Artificial/adverse effects ; Defibrillators, Implantable/adverse effects ; Heart Ventricles/diagnostic imaging ; Retrospective Studies ; Heart Injuries/diagnostic imaging ; Heart Injuries/etiology
Language	English
Publishing date	2024-01-08
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	1025989-2
ISSN	1540-8167 ; 1045-3873
ISSN (online)	1540-8167
ISSN	1045-3873
DOI	10.1111/jce.16181
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Article ; Online: Electrocardiographic Predictors of Complete Heart Block During Right Ventricular Lead Implantation in Patients Who Underwent Cardiac Resynchronization Therapy.

Celikyurt, Umut / Acar, Burak / Agacdiken, Aysen / Vural, Ahmet

The American journal of cardiology

2023 Volume 201, Page(s) 62–67

Abstract: Cardiac resynchronization therapy (CRT) device procedures have their own complications in addition to the complications associated with standard pacemaker implantations. This study aimed to analyze the predictors of the right bundle branch injury ... ...

Abstract	Cardiac resynchronization therapy (CRT) device procedures have their own complications in addition to the complications associated with standard pacemaker implantations. This study aimed to analyze the predictors of the right bundle branch injury resulting in complete heart block (CHB) during right ventricular (RV) lead implantation in patients who underwent CRT with defibrillator. We conducted an observational study of consecutive 790 patients who underwent CRT with defibrillator device implantation at our institution from 2010 to 2022. Relevant clinical information and complete data regarding the echocardiographic data, implantation procedure, and clinical follow-up were collected into a computerized database. A total of 29 patients (3.7%) had CHB during RV lead implantation. In multivariate analysis, left axis deviation (odds ratio [OR] 2.408, 95% confidence interval [CI] 1.025 to 5.658, p = 0.044), QRS width (OR 1.022, 95% CI 1.001 to 1.043, p = 0.035) and QRS alternans (OR 4.214, 95% CI 1.788 to 9.930, p = 0.001) were found independently related to right bundle branch injury resulting in CHB development during RV lead implantation. In conclusion, left axis deviation, QRS width, and QRS alternans were associated with a higher rate of CHB, and these findings provide insight into optimal and safe CRT device implantation strategies based on preprocedural characteristics.
MeSH term(s)	Humans ; Cardiac Resynchronization Therapy/methods ; Treatment Outcome ; Defibrillators, Implantable ; Electrocardiography ; Heart Block/therapy ; Heart Failure
Language	English
Publishing date	2023-06-21
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2023.05.072
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Article ; Online: Prognostic value of non-alcoholic fatty liver disease fibrosis score in patients undergoing cardiac resynchronization therapy.

Acar, Burak / Celikyurt, Umut / Agacdiken, Aysen / Vural, Ahmet

Pacing and clinical electrophysiology : PACE

2023 Volume 46, Issue 3, Page(s) 251–257

Abstract: Background: Cardiac resynchronization therapy (CRT) is an effective option in the treatment of patients with heart failure and wide QRS. Non-alcoholic fatty liver disease (NAFLD) fibrosis score (NFS) has been shown to predict cardiac events in several ... ...

Abstract	Background: Cardiac resynchronization therapy (CRT) is an effective option in the treatment of patients with heart failure and wide QRS. Non-alcoholic fatty liver disease (NAFLD) fibrosis score (NFS) has been shown to predict cardiac events in several patient populations. However, the relationship between NFS and response to CRT has not been investigated. The aim of the study was to investigate the predictive role of NFS in the assessment of response after CRT. Methods: Three hundred thirty-six patients with heart failure undergoing CRT were prospectively studied. Liver fibrosis were assessed according to the non-alcoholic fatty liver disease fibrosis score (NFS), which includes age, body mass index, impaired fasting glycemia or diabetes mellitus, aspartate aminotransferase /alanine aminotransferase ratio, platelets, and albumin. Echocardiographic response to CRT was defined by a ≥15% reduction in left ventricular end-systolic volume at six months at follow-up. Results: Two hundred thirty-eight patients (71%) had CRT response after 6 months of follow-up. Receiver-operator characteristic curve analysis showed NFS cutoff value of < -1.12 for predicting CRT response with a sensitivity of 70.4% and a specificity of 52.9%. The patients were also divided into four groups according to the quartiles of NFS. The proportion of response to CRT was increased with lower level of NFS value. Multivariate logistic regression analysis demonstrated the NFS score < -1.12 and LVIDs were independent predictors of the CRT response. In the second model of analysis which included NFS, quartiles demonstrated that fourth NFS quartile and LVIDs were independent predictors of CRT response. Conclusion: Liver fibrosis assessed by NFS can provide valuable information to predict reverse remodeling in patients undergoing CRT. The present study supports monitoring of NFS to improve preoperative risk stratification of these patients.
MeSH term(s)	Humans ; Prognosis ; Non-alcoholic Fatty Liver Disease/therapy ; Cardiac Resynchronization Therapy ; Liver Cirrhosis/therapy ; Heart Failure/therapy
Language	English
Publishing date	2023-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	424437-0
ISSN	1540-8159 ; 0147-8389
ISSN (online)	1540-8159
ISSN	0147-8389
DOI	10.1111/pace.14657
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Zs.A 1466: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Pulmonary fibrotic-like changes on follow-up chest CT exam in patients recovering from COVID-19 pneumonia.

Vural, Ahmet / Kahraman, Ahmet Nedim

Tuberkuloz ve toraks

2021 Volume 69, Issue 4, Page(s) 492–498

Abstract: Introduction: To date, there is limited data on the long-term changes in the lungs of patients recovering from coronavirus (COVID-19) pneumonia. In order to evaluate pulmonary sequelae, it was planned to investigate fibrotic changes observed as sequelae ...

Title translation	TCOVID-19 pnömonisi geçiren hastalarda takip tomografisinde akciğer parankiminde izlenen fibrotik değişiklikler.
Abstract	Introduction: To date, there is limited data on the long-term changes in the lungs of patients recovering from coronavirus (COVID-19) pneumonia. In order to evaluate pulmonary sequelae, it was planned to investigate fibrotic changes observed as sequelae in lung tissue in 3-6-month control thorax computerized tomography (CT) scans of moderate-to-severe COVID-19 pneumonia survivors. Materials and methods: A total of 84 patients (mean age: 67.3 years ±15) with moderate-to-severe pneumonia on chest tomography at the time of diagnosis were included in the study, of which 51 (61%) were males and 33 (39%) were females. Initial and follow-up CT scans averaged 8.3 days ± 2.2 and 112.1 days ± 14.6 after symptom onset, respectively. Participants were recorded in two groups as those with and without fibrotic-like changes such as traction bronchiectasis, fibrotic - parenchymal bands, honeycomb appearance according to 3-6 months follow-up CT scans. Differences between the groups were evaluated with a two-sampled t-test. Logistic regression analyzes were performed to determine independent predictive factors of fibrotic-like sequelae changes. Result: On follow-up CTs, fibrotic-like changes were observed in 29 (35%) of the 84 participants (Group 1), while the remaining 55 (65%) showed complete radiological recovery (Group 2). With logistic regression analysis, hospital stay of 22 days or longer (OR: 4.9; 95% CI: 20, 32; p< 0.05) and a CT score of 15 or more at diagnosis (OR: 2.2; 95% CI: 13.5, 18; p< 0.05) were found to be an independent predictor for sequelae fibrotic changes in lung tissue. Conclusions: More than one-third of patients who survived COVID-19 pneumonia had fibrotic-like sequelae changes in the lung parenchyma. These changes were found to be associated with the presence of severe pneumonia at the time of diagnosis and longer hospital stay.
MeSH term(s)	Aged ; COVID-19 ; Female ; Follow-Up Studies ; Humans ; Lung/diagnostic imaging ; Male ; Pneumonia/diagnostic imaging ; Retrospective Studies ; SARS-CoV-2 ; Thorax ; Tomography, X-Ray Computed
Language	English
Publishing date	2021-12-26
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2468802-2
ISSN	0494-1373
ISSN	0494-1373
DOI	10.5578/tt.20219607
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Article: Fast three-dimensional time-of-flight magnetic resonance angiography: Should it be used in routine neuroimaging for headaches?

Nedim, Kahraman Ahmet / Vural, Ahmet

International journal of health sciences

2021 Volume 15, Issue 5, Page(s) 28–33

Abstract: Objectives: We aimed to evaluate the diagnostic efficacy of fast three-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) in the detection of cerebral aneurysms.: Methods: We screened 1589 patients over a 3-year period, who ... ...

Abstract	Objectives: We aimed to evaluate the diagnostic efficacy of fast three-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) in the detection of cerebral aneurysms. Methods: We screened 1589 patients over a 3-year period, who underwent a magnetic resonance imaging for headache. Fast 3D TOF MRA images taken in addition to routine neuroimaging sequences, which were examined by two independent observers to assess cerebral aneurysms. Results: Sixty-nine aneurysms were detected in 63 patients. The locations of the aneurysms were as follows: Middle cerebral artery, 27.5% ( Conclusion: Considering the mortality and morbidity of subarachnoid hemorrhages, 3D TOF MRA is a successful, non-invasive method for detecting cerebral aneurysms. Results of the present study have shown that adding 3D TOF MRA to the routine brain imaging protocol is a beneficial tool for diagnosis.
Language	English
Publishing date	2021-08-26
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	2603595-9
ISSN	1658-3639
ISSN	1658-3639
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Article ; Online: Comparison of selective coronary angiography through the ablation catheter versus conventional coronary angiography to guide ablation of premature ventricular contractions originating from aortic cusp.

Celikyurt, Umut / Acar, Burak / Agacdiken, Aysen / Vural, Ahmet

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

2022 Volume 65, Issue 3, Page(s) 711–715

Abstract: Background: Intraprocedural coronary angiography (CA) is recommended in patients undergoing ablation in aortic cusps to assess the relation of catheter tip and coronary ostia. In this report, we aimed to compare selective coronary angiography (SCA) ... ...

Abstract	Background: Intraprocedural coronary angiography (CA) is recommended in patients undergoing ablation in aortic cusps to assess the relation of catheter tip and coronary ostia. In this report, we aimed to compare selective coronary angiography (SCA) through the contact force (CF)-sensing radiofrequency catheter with conventional coronary angiography (CCA) to guide ablation of premature ventricular contractions (PVC). Methods: This was a retrospective observational cohort study of prospectively collected data of 87 consecutive patients undergoing PVC ablation at a single institution between February 2016 and June 2021. Forty-six patients (53%) underwent SCA and forty-one patients (47%) underwent CCA. Data were consecutively collected case-by-case and entered into a computerized database. Procedural characteristics, complications, and clinical outcomes were compared between the SCA and CCA groups. Results: Successful ablation was achieved in seventy-seven (89%) patients. Total procedure and fluoroscopy time and radiation dose were significantly lower in SCA group (93 ± 22 min vs 102 ± 20 min, p = 0.042; 12 ± 3 min vs 14 ± 4 min, p = 0.030; 3292 ± 1221 μGy m Conclusions: Selective coronary angiography through the CF-sensing ablation catheter to assess the relation between the ablation site and the coronary ostia is feasible and safe. This technique precludes the requirement of an additional arterial access and decreases the total procedure and fluoroscopy time and radiation dose.
MeSH term(s)	Humans ; Ventricular Premature Complexes/diagnostic imaging ; Ventricular Premature Complexes/surgery ; Coronary Angiography ; Cohort Studies
Language	English
Publishing date	2022-08-05
Publishing country	Netherlands
Document type	Observational Study ; Journal Article
ZDB-ID	1329179-8
ISSN	1572-8595 ; 1383-875X
ISSN (online)	1572-8595
ISSN	1383-875X
DOI	10.1007/s10840-022-01324-8
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