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  1. Article ; Online: Caring for Traumatized Elders: Lessons Learned From Trauma-Informed Care.

    Popescu, Dominique / Mellen, Emily / Ander, Ilana / Vyas, Chirag M / Ishikawa, Rachel Zack / Stern, Theodore A

    The primary care companion for CNS disorders

    2024  Volume 26, Issue 2

    MeSH term(s) Humans ; Aged ; Mental Disorders/therapy ; Psychological Trauma/therapy
    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.23f03643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Late-Life Depression: A Narrative Review on Risk Factors and Prevention.

    Vyas, Chirag M / Okereke, Olivia I

    Harvard review of psychiatry

    2020  Volume 28, Issue 2, Page(s) 72–99

    Abstract: Learning objectives: After participating in this activity, learners should be better able to:• Identify risk factors for late-life depression• Evaluate strategies to prevent late-life depression ABSTRACT: Late-life depression (LLD) is one of the major ... ...

    Abstract Learning objectives: After participating in this activity, learners should be better able to:• Identify risk factors for late-life depression• Evaluate strategies to prevent late-life depression ABSTRACT: Late-life depression (LLD) is one of the major sources of morbidity and mortality in the world. Because LLD is related to increased public health burden, excess health care costs and utilization, reduced quality of life, and increased mortality, prevention is a priority. Older adults differ from younger adults with respect to key features, such as their chronicity and lifetime burden of depression and their constellation of comorbidities and risk factors. LLD likely arises from a complex interplay of risk factors, including medical, physiologic, psychosocial, behavioral, and environmental factors. Thus, a comprehensive understanding of LLD risk factors is necessary to inform prevention strategies. In this narrative literature review, we address both the risk architecture of LLD and several potential strategies for prevention. Our description of LLD risk factors and prevention approaches is informed by the framework developed by the National Academy of Medicine (formerly, Institute of Medicine), which includes indicated, selective, and universal approaches to prevention.
    MeSH term(s) Aging/psychology ; Comorbidity ; Depression/prevention & control ; Humans ; Primary Prevention/methods ; Randomized Controlled Trials as Topic ; Risk Factors
    Language English
    Publishing date 2020-02-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1174775-4
    ISSN 1465-7309 ; 1067-3229
    ISSN (online) 1465-7309
    ISSN 1067-3229
    DOI 10.1097/HRP.0000000000000240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Vitamin D and Psychosis in Alzheimer Disease: New Insights From Pharmacogenomics Research.

    Vyas, Chirag M / Okereke, Olivia I

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2019  Volume 27, Issue 9, Page(s) 918–919

    MeSH term(s) Alzheimer Disease ; Humans ; Pharmacogenetics ; Psychotic Disorders ; Vitamin D
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2019-06-04
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2019.05.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Assessment and Treatment of Abnormal Involuntary Movements: A Clinically Focused Narrative Review.

    Petriceks, Aldis / Vyas, Chirag M / Paudel, Shreedhar / Donovan, Abigail L / Van Alphen, Manjola U / Stern, Theodore A

    Harvard review of psychiatry

    2024  Volume 32, Issue 2, Page(s) 47–57

    Abstract: Learning objectives: After participating in this CME activity, the psychiatrist should be better able to:• Categorize and describe different types of abnormal involuntary movements (AIMs).• Identify assessment tools and treatment options for AIMs.: ... ...

    Abstract Learning objectives: After participating in this CME activity, the psychiatrist should be better able to:• Categorize and describe different types of abnormal involuntary movements (AIMs).• Identify assessment tools and treatment options for AIMs.
    Abstract: Abnormal involuntary movements (AIMs) comprise a diverse group of movement disorders characterized by uncontrolled and unintended movements (e.g., tremors, tics, dystonia). AIMs can occur at any stage of life and pose significant challenges for clinicians. It is difficult to determine their underlying causes due to the complex neurobiological mechanisms involved. Therefore, it is crucial to quantify the severity and progression of AIMs using well-validated measurement scales, such as the Abnormal Involuntary Movement Scale (AIMS). By employing reliable assessment approaches, clinicians can objectively evaluate the motoric manifestations of AIMs and track them over time. Treatment of AIMs varies depending on their nature and etiology. While AIMs often respond to treatment, serious side effects can undermine treatment efficacy. In this clinically focused narrative review, we categorize different types of AIMs and discuss their neurobiological aspects. Further, we emphasize the importance of using well-validated measurement scales for accurate assessment and discuss available treatment modalities that target the specific AIMs manifestations. Additionally, we cover the need for comprehensive care to address the multifaceted nature of AIMs, accounting for their physical manifestations as well as their psychological, social, and functional toll on patients. By embracing a multidisciplinary approach, health care professionals can provide patient-centered care that promotes overall well-being and enhances the lives of patients coping with AIMs. Regular follow-up assessments are necessary to monitor treatment response, adjust medications when needed, and provide ongoing support for individuals affected by AIMs.
    MeSH term(s) Humans ; Dyskinesias ; Movement Disorders ; Dystonia
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1174775-4
    ISSN 1465-7309 ; 1067-3229
    ISSN (online) 1465-7309
    ISSN 1067-3229
    DOI 10.1097/HRP.0000000000000390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Drug-Induced Abnormal Involuntary Movements: Prevalence and Treatment.

    Paudel, Shreedhar / Donovan, Abigail L / Petriceks, Aldis / Vyas, Chirag M / Van, Manjola U / Stern, Theodore A

    The primary care companion for CNS disorders

    2023  Volume 25, Issue 3

    Abstract: The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service ... ...

    Abstract The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.
    MeSH term(s) Humans ; Prevalence ; Mental Disorders/drug therapy ; Mental Disorders/epidemiology ; Psychiatry ; Hospitals, General ; Comorbidity ; Referral and Consultation
    Language English
    Publishing date 2023-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.22f03305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Use of Physical Restraints in the Emergency Department: Rationale, Risks, and Benefits.

    Donovan, Abigail L / Petriceks, Aldis H / Paudel, Shreedhar / Vyas, Chirag M / Stern, Theodore A

    The primary care companion for CNS disorders

    2023  Volume 25, Issue 3

    Abstract: The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service ... ...

    Abstract The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.
    MeSH term(s) Humans ; Restraint, Physical ; Mental Disorders/diagnosis ; Mental Disorders/therapy ; Psychiatry ; Emergency Service, Hospital ; Hospitals, General ; Referral and Consultation
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.22f03320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Acute Psychosis: Differential Diagnosis, Evaluation, and Management.

    Vyas, Chirag M / Petriceks, Aldis H / Paudel, Shreedhar / Donovan, Abigail L / Stern, Theodore A

    The primary care companion for CNS disorders

    2023  Volume 25, Issue 2

    Abstract: The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service ... ...

    Abstract The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.
    MeSH term(s) Humans ; Diagnosis, Differential ; Psychotic Disorders/diagnosis ; Psychotic Disorders/therapy ; Mental Disorders/epidemiology ; Psychiatry ; Comorbidity ; Hospitals, General ; Referral and Consultation
    Language English
    Publishing date 2023-03-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.22f03338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Child Maltreatment Among Older Adults: A Narrative Review of Psychotherapeutic Interventions and Clinical Considerations.

    Ishikawa, Rachel Zack / Ander, Ilana / Popescu, Dominique L / Vyas, Chirag M / Okereke, Olivia I

    Clinical gerontologist

    2023  , Page(s) 1–15

    Abstract: Objectives: The goals of this narrative review are to review the literature on psychotherapeutic interventions for older adults with histories of child maltreatment (CM) and to examine the unique considerations for assessing, diagnosing, and treating ... ...

    Abstract Objectives: The goals of this narrative review are to review the literature on psychotherapeutic interventions for older adults with histories of child maltreatment (CM) and to examine the unique considerations for assessing, diagnosing, and treating older adults with CM histories.
    Methods: Online database searches were conducted to identify the extant research into the efficacy of psychotherapeutic interventions for older adults with CM-related trauma.
    Results: Eight studies met inclusion criteria. The primary target diagnoses were post-traumatic stress disorder and depression. Psychotherapeutic interventions included Narrative Exposure Therapy, exposure-based treatments, Life Review Therapy, integrated treatments, and a spiritually-focused group therapy.
    Conclusions: While limited in number and generalizability due to study design and sample size and characteristics, the studies provide preliminary evidence of potentially effective psychotherapeutic treatments for older adults with CM histories. Further research is needed to determine the most effective psychotherapeutic interventions for this population.
    Clinical implications: Many older adults suffer for decades with the repercussions of CM. Due to knowledge gaps regarding best practices for treating older adults with CM histories, many clinicians are poorly equipped to treat this population. Therefore, awareness of CM-related pathology and familiarity with effective psychotherapeutic interventions are essential for clinicians to meet the needs of this population.
    Language English
    Publishing date 2023-05-31
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 226146-7
    ISSN 1545-2301 ; 0731-7115
    ISSN (online) 1545-2301
    ISSN 0731-7115
    DOI 10.1080/07317115.2023.2219671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Prescription for Deprescribing Antipsychotics: Managing Polypharmacy in Schizophrenia.

    Paudel, Shreedhar / Vyas, Chirag M / Stern, Theodore A

    The primary care companion for CNS disorders

    2020  Volume 22, Issue 6

    Abstract: The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service ... ...

    Abstract The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.
    MeSH term(s) Antipsychotic Agents/therapeutic use ; Deprescriptions ; Humans ; Polypharmacy ; Prescriptions ; Schizophrenia/drug therapy
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2020-12-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.20f02708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: New-Onset Paranoia in an Elderly Woman With Bipolar Disorder: Differential Diagnosis, Evaluation, and Treatment.

    Paudel, Shreedhar / Vyas, Chirag M / Peay, Celeste / Sorg, Emily / Abuali, Inas / Stern, Theodore A

    The primary care companion for CNS disorders

    2022  Volume 24, Issue 4

    Abstract: The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service ... ...

    Abstract The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.
    MeSH term(s) Aged ; Bipolar Disorder/complications ; Bipolar Disorder/diagnosis ; Bipolar Disorder/therapy ; Diagnosis, Differential ; Female ; Hospitals, General ; Humans ; Mental Disorders/therapy ; Paranoid Disorders/complications ; Paranoid Disorders/diagnosis ; Paranoid Disorders/therapy ; Psychiatry ; Referral and Consultation
    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.21f03141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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