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Book ; Thesis: Die metabolischen und molekularen Auswirkungen verschiedener Hochfettdiäten im Nagetiermodell

Wällisch, Wolfgang

2013

Author's details	vorgelegt von Wolfgang Wällisch
Language	German
Size	128 S. : Ill., graph. Darst.
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Regensburg, Univ., Diss., 2013
HBZ-ID	HT017772007
Database	Catalogue ZB MED Medicine, Health

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2013 D 847	order for loan	Magazin

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Article ; Conference proceedings: Quality Assessment in Pediatric Cardiology Using Network Technologies

Wällisch, W. / Dittrich, S. / Cesnjevar, R. / Purbujo, A. / Schöffl, I. / Kapsner, L. / Mang, J.

The Thoracic and Cardiovascular Surgeon

2024 Volume 72, Issue S 02

Event/congress	56th Annual Meeting of the German Society for Pediatric Cardiology (DGPK), Congress Center Hamburg, 2024-02-17
Language	English
Publishing date	2024-01-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	800050-5
ISSN	1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
ISSN (online)	1439-1902
ISSN	0171-6425 ; 0946-4778 ; 0172-6137
DOI	10.1055/s-0044-1780712
Database	Thieme publisher's database

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Article ; Conference proceedings: New Exercise Test Variables for the Decision Process in Pulmonary Valve Replacement

Schöffl, I. / Weigelt, A. / Dittrich, S. / Rottermann, K. / Wällisch, W. / Deindl, R.

The Thoracic and Cardiovascular Surgeon

2024 Volume 72, Issue S 02

Event/congress	56th Annual Meeting of the German Society for Pediatric Cardiology (DGPK), Congress Center Hamburg, 2024-02-17
Language	English
Publishing date	2024-01-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	800050-5
ISSN	1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
ISSN (online)	1439-1902
ISSN	0171-6425 ; 0946-4778 ; 0172-6137
DOI	10.1055/s-0044-1780719
Database	Thieme publisher's database

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Article ; Conference proceedings: Exercise Echocardiography Combined with Cardiopulmonary Exercise Testing in Small Children

Schöffl, I. / Weigelt, A. / Rottermann, K. / Dittrich, S. / Wällisch, W.

The Thoracic and Cardiovascular Surgeon

2023 Volume 71, Issue S 02

Event/congress	55th Annual Meeting of the German Society for Pediatric Cardiology (DGPK), Congress Center Hamburg, 2023-02-11
Language	English
Publishing date	2023-01-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	800050-5
ISSN	1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
ISSN (online)	1439-1902
ISSN	0171-6425 ; 0946-4778 ; 0172-6137
DOI	10.1055/s-0043-1761890
Database	Thieme publisher's database

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Article ; Conference proceedings: L.I.S.A.: Quality of Life in Children and Families with Congenital Heart Disease—Interventions in Stationary and Ambulant Sectors

Wällisch, W. / Eger, F. / Fürstenfeld, N. / Deistler, A. / Storch, T. / Purbojo, A. / Dittrich, S.

The Thoracic and Cardiovascular Surgeon

2023 Volume 71, Issue S 02

Event/congress	55th Annual Meeting of the German Society for Pediatric Cardiology (DGPK), Congress Center Hamburg, 2023-02-11
Language	English
Publishing date	2023-01-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	800050-5
ISSN	1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
ISSN (online)	1439-1902
ISSN	0171-6425 ; 0946-4778 ; 0172-6137
DOI	10.1055/s-0043-1761838
Database	Thieme publisher's database

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Article ; Online: COPHYD (Corona Owed Physical Deficiency): The Impact of Lockdown on Cardiopulmonary Function in Paediatric Cardiology Patients.

Stäbler, Tim / Weigelt, Annika / Rottermann, Kathrin / Wällisch, Wolfgang / Hübner, Matthias / Dittrich, Sven / Schöffl, Isabelle

Klinische Padiatrie

2022 Volume 235, Issue 5, Page(s) 290–296

Abstract: Introduction: Due to the Corona-lockdowns the closure of sports facilities and schools has led to a decline in physical activity (PA) for months. PA is essential for maintaining cardiopulmonary function assessed by peak oxygen uptake. Since peak oxygen ... ...

Title translation	COPHYD (Corona Owed Physical Deficiency): Der Einfluss des Lockdown auf die kardiopulmonare Funktion bei kinderkardiologischen Patienten.
Abstract	Introduction: Due to the Corona-lockdowns the closure of sports facilities and schools has led to a decline in physical activity (PA) for months. PA is essential for maintaining cardiopulmonary function assessed by peak oxygen uptake. Since peak oxygen uptake represents the best predictor for mortality and morbidity in children with congenital heart disease the impact of lockdowns on this parameter is vital. Methods: We evaluated retrospectively cardiopulmonary exercise data from our patient collective from before lockdown with twin-paired data from during lockdown. The twin-pairing was achieved by matching patients with similar heart disease, age, sex, and test method. Cardiopulmonary exercise testing was achieved on either the treadmill or the bicycle. Results: We were able to twin-pair 90 cases (26 twins with heart disease and 19 healthy twins). There was a significant decrease of cardiopulmonary function (V̇O Conclusion: We observed a significant decline of peak oxygen uptake during lockdown in the group of congenital heart disease (CHD) patients. This involved a loss of cardiac function as well as pulmonary function. This could be explained by limited access to sports facilities and restriction of regular daily movement due to school closure and overprotection. Healthy children improved their pulmonary function. This might be an indication of an improvement of exercise during confinement.Aufgrund des Corona-Lockdowns hat die Schließung von Sportanlagen und Schulen über Monate zu einem Rückgang der körperlichen Aktivität geführt. Körperliche Aktivität ist für die Aufrechterhaltung der kardiopulmonalen Funktion, bewertet durch die maximale Sauerstoffaufnahme, unerlässlich. Da die maximale Sauerstoffaufnahme der beste Prädiktor für Mortalität und Morbidität bei Kindern mit angeborenen Herzerkrankungen ist, sind die Auswirkungen des Lockdowns auf diesen Parameter von entscheidender Bedeutung. Spiroergometriedaten unseres Patientenkollektivs aus der Zeit vor dem Lockdown wurde mit Daten von statistischen Zwillingen aus dem gleichen Kollektiv während des Lockdowns verglichen. Die Zwillingspaarung wurde erreicht, indem Patienten mit ähnlichen Herzerkrankungen, Alter, Geschlecht und Testmodalitäten verglichen wurden. Die Spiroergometrie wurde entweder auf dem Laufband oder auf dem Fahrrad durchgeführt. Insgesamt wurden 90 Datensätze verbunden (26 Zwillinge mit Herzkrankheit und 19 gesunde Zwillinge). In der Kohorte der Herzerkrankten konnte eine signifikante Verschlechterung der kardiopulmonalen Funktion (V̇O
MeSH term(s)	Child ; Humans ; Retrospective Studies ; Heart Defects, Congenital ; Cardiology
Language	English
Publishing date	2022-09-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	120650-3
ISSN	1439-3824 ; 0300-8630
ISSN (online)	1439-3824
ISSN	0300-8630
DOI	10.1055/a-1906-1187
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Impact of premature birth on cardiopulmonary function in later life.

Weigelt, Annika / Bleck, Steffen / Huebner, Matthias Jens / Rottermann, Kathrin / Waellisch, Wolfgang / Morhart, Patrick / Abu-Tair, Tariq / Dittrich, Sven / Schoeffl, Isabelle

European journal of pediatrics

2023 Volume 182, Issue 7, Page(s) 3265–3274

Abstract: Pulmonary function is reduced in children after preterm birth. The variety of subgroups ranges from early to late preterm births. Limitations in pulmonary function can be observed even after late preterm birth without signs of bronchopulmonary dysplasia ... ...

Abstract	Pulmonary function is reduced in children after preterm birth. The variety of subgroups ranges from early to late preterm births. Limitations in pulmonary function can be observed even after late preterm birth without signs of bronchopulmonary dysplasia and/or history of mechanical ventilation. Whether this reduction in lung function is reflected in the cardiopulmonary capacity of these children is unclear. This study aims to investigate the impact of moderate to late premature birth on cardiopulmonary function. Cardiopulmonary exercise testing on a treadmill was performed by 33 former preterm infants between 8 and 10 years of age who were born between 32 + 0 and 36 + 6 weeks of gestation and compared with a control group of 19 children born in term of comparable age and sex. The former preterm children achieved comparable results to the term-born controls with respect to most of the cardiopulmonary exercise parameters [Formula: see text]. The only differences were in a slightly higher oxygen uptake efficiency slope [Formula: see text] and higher peak minute ventilation [Formula: see text] in the group of children born preterm. With respect to heart rate recovery [Formula: see text] and breathing efficiency [Formula: see text], there were no significant differences. Conclusion: Children born preterm did not show limitations in cardiopulmonary function in comparison with matched controls. What is known: • Preterm birth is associated with reduced pulmonary function in later life, this is also true for former late preterms. • As a consequence of being born premature, the lungs have not finished their important embryological development. Cardiopulmonary fitness is an important parameter for overall mortality and morbidity in children and adults and a good pulmonary function is therefore paramount. What is new: • Children born prematurely were comparable to an age- and sex-matched control group with regards to almost all cardiopulmonary exercise variables. • A significantly higher OUES, a surrogate parameter for VO
MeSH term(s)	Infant ; Child ; Adult ; Pregnancy ; Female ; Humans ; Infant, Newborn ; Premature Birth ; Infant, Premature ; Lung ; Bronchopulmonary Dysplasia/complications ; Exercise Test
Language	English
Publishing date	2023-05-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	194196-3
ISSN	1432-1076 ; 0340-6199 ; 0943-9676
ISSN (online)	1432-1076
ISSN	0340-6199 ; 0943-9676
DOI	10.1007/s00431-023-04952-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Sports despite masks: no negative effects of FFP2 face masks on cardiopulmonary exercise capacity in children.

Weigelt, Annika / Schöffl, Isabelle / Rottermann, Kathrin / Wällisch, Wolfgang / Müller, Sarina Katrin / Dittrich, Sven / Hübner, Matthias Jens

European journal of pediatrics

2023 Volume 183, Issue 2, Page(s) 639–648

Abstract: Face masks were recognized as one of the most effective ways to prevent the spread of the COVID-19 virus in adults. These benefits were extended to children and adolescents. However, the fear of negative consequences from wearing a face mask during ... ...

Abstract	Face masks were recognized as one of the most effective ways to prevent the spread of the COVID-19 virus in adults. These benefits were extended to children and adolescents. However, the fear of negative consequences from wearing a face mask during physical exercise led to cancellations of physical education lessons. This further decreased the amount of physical activity available to children and adolescents during the pandemic. However, there is little published data on the potential adverse effects of wearing the most effective and partially mandatory FFP2/N95 face masks during PE or physical activity (PA) in this age. Even though the pandemic has been declared as passed by the WHO, the rise of a new pandemic and thus the use of face masks for limiting its spread is inevitable, so we need to be better prepared for alternative options to lockdown and limitation of PA in such a scenario. Twenty healthy children aged 8-10 years performed two identical cardiopulmonary exercise tests as an incremental step test on a treadmill within an interval of 2 weeks, one time without wearing a protective mask and one time wearing an FFP2 mask. The cardiopulmonary exercise parameter and especially the end-expiratory gas exchange for oxygen and carbon dioxide (petO Conclusion: In this study, no significant differences in the cardiorespiratory function at peak exercise could be discerned when wearing an FFP2/N95 face mask. While the end-tidal values for CO What is known: • Wearing a face mask has an influence on psychological, social, and physiological functions in adults. • Because of the observed effects of wearing face masks in adults, physical activity in children was limited during the pandemic. What is new: • Wearing an FFP2/N95 mask during physical activity did not lead to hypercapnia or hypoxia in children in this study. • Even though end-tidal CO2 values were significantly higher and end-tidal O2 values significantly lower when wearing an FFP2/N95 face mask, no pathological values were reached.
MeSH term(s)	Adolescent ; Adult ; Male ; Child ; Female ; Humans ; Carbon Dioxide ; Exercise Tolerance ; Hypercapnia ; Masks ; Hypoxia ; Oxygen ; Pandemics
Chemical Substances	Carbon Dioxide (142M471B3J) ; Oxygen (S88TT14065)
Language	English
Publishing date	2023-11-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	194196-3
ISSN	1432-1076 ; 0340-6199 ; 0943-9676
ISSN (online)	1432-1076
ISSN	0340-6199 ; 0943-9676
DOI	10.1007/s00431-023-05316-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Cardiopulmonary function in paediatric post-COVID-19: a controlled clinical trial.

Schoeffl, Isabelle / Raming, Roman / Tratzky, Jan-Philipp / Regensburger, Adrian P / Kraus, Calvin / Waellisch, Wolfgang / Trollmann, Regina / Woelfle, Joachim / Dittrich, Sven / Heiss, Rafael / Knieling, Ferdinand / Weigelt, Annika

European journal of pediatrics

2024 Volume 183, Issue 4, Page(s) 1645–1655

Abstract: Recently, the importance of post-COVID-19 in children has been recognized in surveys and retrospective chart analysis. However, objective data in the form of cardiopulmonary exercise test as performed in adults suffering from this condition are still ... ...

Abstract	Recently, the importance of post-COVID-19 in children has been recognized in surveys and retrospective chart analysis. However, objective data in the form of cardiopulmonary exercise test as performed in adults suffering from this condition are still lacking. This study aimed to investigate the cardiopulmonary effects of post-COVID-19 on children and adolescents. In this cross-sectional study (the FASCINATE study), children fulfilling the criteria of post-COVID-19 and an age- and sex-matched control group underwent cardiopulmonary exercise testing on a treadmill and completed a questionnaire with regard to physical activity before, during and after the infection with SARS-CoV-2. We were able to recruit 20 children suffering from post-COVID-19 (mean age 12.8 ± 2.4 years, 60% females) and 28 control children (mean age 11.7 ± 3.5 years, 50% females). All participants completed a maximal treadmill test with a significantly lower
MeSH term(s)	Adult ; Female ; Adolescent ; Humans ; Child ; Male ; COVID-19 ; Retrospective Studies ; Cross-Sectional Studies ; SARS-CoV-2 ; Lung ; Exercise Test/methods
Language	English
Publishing date	2024-01-09
Publishing country	Germany
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	194196-3
ISSN	1432-1076 ; 0340-6199 ; 0943-9676
ISSN (online)	1432-1076
ISSN	0340-6199 ; 0943-9676
DOI	10.1007/s00431-024-05421-w
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Article: Fitter Fontans for future-Impact of physical exercise on cardiopulmonary function in Fontan patients.

Weigelt, Annika / Fritsch, Regina / Rottermann, Kathrin / Wällisch, Wolfgang / Moosmann, Julia / Dittrich, Sven / Purbojo, Ariawan / Schöffl, Isabelle

Frontiers in cardiovascular medicine

2022 Volume 9, Page(s) 972652

Abstract: Background: In Fontans, exercise tolerance is poorer compared to their healthy peers. Higher : Methods: We performed cardiopulmonary exercise testing in 24 Fontan patients who had engaged in physical activity for a minimum of 3 h per week over their ... ...

Abstract	Background: In Fontans, exercise tolerance is poorer compared to their healthy peers. Higher Methods: We performed cardiopulmonary exercise testing in 24 Fontan patients who had engaged in physical activity for a minimum of 3 h per week over their lifetime. As a control we performed cardiopulmonary exercise testing in 20 Fontan patients who had undertaken no physical activity or <3 h per week in the past. Results: A total of 44 Fontan patients was included (mean age 18.1 years). The mean parameters measured at peak exercise differed significantly between the active and inactive group (peak oxygen uptake [ Conclusions:
Language	English
Publishing date	2022-09-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2022.972652
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