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  1. Article ; Online: Some Non-Obvious Consequences of Non-Extensiveness of Entropy.

    Wilk, Grzegorz / Włodarczyk, Zbigniew

    Entropy (Basel, Switzerland)

    2023  Volume 25, Issue 3

    Abstract: Non-additive (or non-extensive) entropies have long been intensively studied and used in various fields of scientific research. This was due to the desire to describe the commonly observed quasi-power rather than the exponential nature of various ... ...

    Abstract Non-additive (or non-extensive) entropies have long been intensively studied and used in various fields of scientific research. This was due to the desire to describe the commonly observed quasi-power rather than the exponential nature of various distributions of the variables of interest when considered in the full available space of their variability. In this work we will concentrate on the example of high energy multiparticle production processes and will limit ourselves to only one form of non-extensive entropy, namely the Tsallis entropy. We will discuss some points not yet fully clarified and present some non-obvious consequences of non-extensiveness of entropy when applied to production processes.
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e25030474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Impact of Levosimendan and Its Metabolites on Platelet Activation Mechanisms in Patients during Antiplatelet Therapy-Pilot Study.

    Sikora, Joanna / Pstrągowski, Krzysztof / Karczmarska-Wódzka, Aleksandra / Wszelaki, Patrycja / Buszko, Katarzyna / Włodarczyk, Zbigniew

    International journal of molecular sciences

    2024  Volume 25, Issue 3

    Abstract: Levosimendan is used for the short-term treatment of severe heart failure or other cardiac conditions. The area of existing clinical applications for levosimendan has increased significantly. This study aimed to assess whether levosimendan and its ... ...

    Abstract Levosimendan is used for the short-term treatment of severe heart failure or other cardiac conditions. The area of existing clinical applications for levosimendan has increased significantly. This study aimed to assess whether levosimendan and its metabolites impact the mechanisms related to platelet activation. In this study, we included patients with coronary artery disease receiving antiplatelet therapy. We analyzed the pharmacodynamic profile using three independent methods to assess platelet activity. The results of the conducted studies indicate a mechanism of levosimendan that affects the function of platelets, causing higher inhibition of platelet receptors and, thus, their aggregation. It is essential to clarify whether levosimendan may affect platelets due to the need to maintain a balance between bleeding and thrombosis in patients treated with levosimendan. This is especially important in the case of perioperative bleeding. This study was conducted in vitro; the research should be continued and carried out in patients to check the complete pharmacokinetic and pharmacodynamic profile.
    MeSH term(s) Humans ; Simendan/pharmacology ; Simendan/therapeutic use ; Platelet Aggregation Inhibitors/pharmacology ; Platelet Aggregation Inhibitors/therapeutic use ; Pilot Projects ; Platelet Aggregation ; Platelet Activation ; Blood Platelets
    Chemical Substances Simendan (349552KRHK) ; Platelet Aggregation Inhibitors
    Language English
    Publishing date 2024-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25031824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Biblical garden – a review, characteristics and definition based on twenty years of research

    Włodarczyk, Zofia

    Folia horticulturae. 2018 Dec. 01, v. 30, no. 2

    2018  

    Abstract: Biblical gardens have existed in the public space for almost 80 years, and yet still up to this moment no scientific definition of this type of garden layout has been developed, nor has any detailed characterization of them been published. Multifaceted, ... ...

    Abstract Biblical gardens have existed in the public space for almost 80 years, and yet still up to this moment no scientific definition of this type of garden layout has been developed, nor has any detailed characterization of them been published. Multifaceted, interdisciplinary research carried out in the years 1996-2017 made it possible to gather detailed data pertaining to 63 biblical gardens all over the world, primarily including the oldest ones. The fundamental characteristics of existing sites were determined on the basis of these results, including their naming in different languages, presentation through a logo and motto, plant selection along with the manner of its presentation, the symbols that they employ, street and garden furniture being used and the arrangements of miniature landscapes. An in-depth analysis of the material that had been gathered made it possible to formulate a scientific definition of a biblical garden as a specific type of greenery arrangement. The specifics of biblical gardens lie in the fact that they possess significant semantic value and are an illustration of the sacred texts of the Bible, one of the greatest works of literature. Various artistic works are being used in their arrangement, in addition to modern forms of design, which highlight sensory values through referring to the senses: sight, touch, hearing, smell and taste.
    Keywords furniture ; gardens ; interdisciplinary research ; landscapes ; languages ; vegetation
    Language English
    Dates of publication 2018-1201
    Size p. 229-248.
    Publishing place Sciendo
    Document type Article
    ZDB-ID 2569108-9
    ISSN 2083-5965 ; 0867-1761
    ISSN (online) 2083-5965
    ISSN 0867-1761
    DOI 10.2478/fhort-2018-0020
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Biblical Gardens in Word Culture: Genesis and History

    Wlodarczyk, Z. / Kapczynska, A.

    Journal of agricultural and environmental ethics

    2019  Volume 32, Issue 5/6, Page(s) 835

    Language English
    Document type Article
    ZDB-ID 1082695-6
    ISSN 1187-7863
    Database Current Contents Nutrition, Environment, Agriculture

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  5. Article ; Online: Preface.

    Wlodarczyk, Zbigniew

    Transplantation proceedings

    2014  Volume 46, Issue 8, Page(s) 2475

    Language English
    Publishing date 2014
    Publishing country United States
    Document type Editorial
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2014.09.141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Biblical Gardens in Word Culture: Genesis and History

    Włodarczyk, Zofia / Kapczyńska, Anna

    Journal of agricultural & environmental ethics. 2019 Dec., v. 32, no. 5-6

    2019  

    Abstract: For nearly 80 years Biblical gardens have been present in the natural and cultural landscape. The first gardens came into existence in the US. The idea to create such gardens spread from the US mainly across Europe, Australia and Israel. These gardens ... ...

    Abstract For nearly 80 years Biblical gardens have been present in the natural and cultural landscape. The first gardens came into existence in the US. The idea to create such gardens spread from the US mainly across Europe, Australia and Israel. These gardens are being made all the time; recently we have observed their dynamic development. This study is to show the effects of the 20 years long scientific work to formulate the original genesis of the Biblical garden idea. The characteristics of 64 facilities situated in 14 countries has been presented for the first time so widely. This enabled us to show both the history of these gardens and how they are situated in the cultural and social context. The effect of various factors inspiring people of various professions to create Biblical gardens both near sacral buildings and within the secular areas has been evidenced. Biblical gardens exercise the principles of gardens of senses and learning gardens. And it is the highly developed semantic layer that makes them stand out.
    Keywords buildings ; cultural landscape ; gardens ; learning ; occupations ; people ; religion ; Australia ; Europe ; Israel ; United States
    Language English
    Dates of publication 2019-12
    Size p. 835-854.
    Publishing place Springer Netherlands
    Document type Article
    ISSN 1187-7863
    DOI 10.1007/s10806-019-09801-3
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Abnormal diurnal blood pressure profile and hypertension-mediated organ damage in nondiabetic chronic kidney disease G1-G3b patients.

    Stróżecki, Paweł / Pluta, Agnieszka / Donderski, Rafał / Włodarczyk, Zbigniew / Manitius, Jacek

    Blood pressure monitoring

    2021  Volume 26, Issue 1, Page(s) 22–29

    Abstract: Objective: Chronic kidney disease (CKD) is associated with high cardiovascular risk. Prevalence of hypertension and hypertension-mediated organ damage (HMOD) increases with CKD progression. Nocturnal blood pressure (BP) is a strong predictor of ... ...

    Abstract Objective: Chronic kidney disease (CKD) is associated with high cardiovascular risk. Prevalence of hypertension and hypertension-mediated organ damage (HMOD) increases with CKD progression. Nocturnal blood pressure (BP) is a strong predictor of cardiovascular complications. This cross-sectional study investigated the link between the diurnal BP profile and HMOD in nondiabetic CKD G1-G3b patients.
    Methods: We investigated 109 CKD patients and 41 apparently healthy persons as controls. All subjects underwent 24-ambulatory blood pressure monitoring (ABPM), echocardiography with left ventricular mass index (LVMI) calculation and pulse wave velocity (PWV) measurement.
    Results: Hypertension was present in 84% of CKD patients. SBP-24 and DBP-24, SBP-day and DBP-day did not differ between CKD and controls. Significant differences were found in SBP-night and DBP-night. The nondipping BP profile (SBP-night/SBP-day ratio ≥0.9) was found in 62% of CKD patients and 32% of controls (P < 0.005). Nocturnal hypertension was found in 56% of CKD patients. LVMI was higher in CKD compared to controls, higher in nondipping than dipping CKD patients, and higher in patients with nocturnal hypertension than without nocturnal hypertension. Abnormal left ventricular geometry was found in 72% nondipping and 43% dipping CKD patients. PWV was higher in CKD than in controls, in patients with nocturnal hypertension than without nocturnal hypertension but did not differ between CKD nondippers and dippers.
    Conclusion: The nondipping BP profile and nocturnal hypertension are associated with HMOD in G1-G3b CKD patients. Hence, there is a need for more extensive use of ABPM for individual risk assessment and personalization of antihypertensive treatment in CKD patients.
    MeSH term(s) Blood Pressure ; Blood Pressure Monitoring, Ambulatory ; Circadian Rhythm ; Cross-Sectional Studies ; Humans ; Hypertension/complications ; Pulse Wave Analysis ; Renal Insufficiency, Chronic/complications
    Language English
    Publishing date 2021-02-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1324472-3
    ISSN 1473-5725 ; 1359-5237
    ISSN (online) 1473-5725
    ISSN 1359-5237
    DOI 10.1097/MBP.0000000000000499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Candida auris Infection in a Meningococcal Septicemia Survivor, Poland.

    Prażyńska, Małgorzata / Zalas-Więcek, Patrycja / Bogiel, Tomasz / Włodarczyk, Zbigniew / Deptuła, Aleksander / Woźniak, Marcin / Gospodarek-Komkowska, Eugenia

    Mycopathologia

    2022  Volume 188, Issue 1-2, Page(s) 135–141

    Abstract: Background: Candida auris is an emerging pathogen that constitutes a serious global health threat. It is difficult to identify without specific approaches, and it can be misidentified with standard laboratory methods, what may lead to inappropriate ... ...

    Abstract Background: Candida auris is an emerging pathogen that constitutes a serious global health threat. It is difficult to identify without specific approaches, and it can be misidentified with standard laboratory methods, what may lead to inappropriate management.
    Case presentation: We report, probably the first in Poland, C. auris isolation from blood cultures and wound swabs of a young male following meningococcal septicaemia, in February 2019. The patient had been previously hospitalized in the United Arab Emirates. The isolate was rapidly identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry and therefore clinicians were promptly informed on the alert pathogen isolation. The targeted antifungal treatment was successful and infection control measures seemed effective. ITS-based identification and subsequent whole genome sequencing showed that the C. auris isolate belongs to South Asian lineage (clade I).
    Conclusions: C. auris is able to cause outbreaks in healthcare settings. Therefore, it is important to quickly identify C. auris isolates in hospital settings so that healthcare facilities can take proper precautions to limit its spread.
    MeSH term(s) Male ; Humans ; Candida ; Poland/epidemiology ; Microbial Sensitivity Tests ; Candidiasis, Invasive
    Language English
    Publishing date 2022-12-30
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 391081-7
    ISSN 1573-0832 ; 0369-299X ; 0301-486X ; 0027-5530
    ISSN (online) 1573-0832
    ISSN 0369-299X ; 0301-486X ; 0027-5530
    DOI 10.1007/s11046-022-00697-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Holistic Long-Term Care Over Elderly Kidney Transplant Recipients.

    Wlodarczyk, E / Wlodarczyk, Z / Paczek, L / Szymanska, A / Glyda, M / Adamowicz, A / Baczyk, G / Ulatowska, A

    Transplantation proceedings

    2018  Volume 50, Issue 6, Page(s) 1900–1903

    Abstract: Kidney transplantation is an optimal method of renal replacement therapy in patients with phase V chronic kidney disease. Elderly patients (older than 60 years) with a kidney transplant create a significant and constantly growing pool of patients with ... ...

    Abstract Kidney transplantation is an optimal method of renal replacement therapy in patients with phase V chronic kidney disease. Elderly patients (older than 60 years) with a kidney transplant create a significant and constantly growing pool of patients with this type of organ transplantation. In this group of patients, long-term care should be particularly stringent and vigilant. Apart from typical conditions associated with chronic kidney disease and possible post-transplant complications as well as side effects of immunosuppressive treatment, the patient also experiences changes and limitations associated with the progress of age and diseases typical for old age, characterized by a higher risk of infection, and changed pharmacokinetics/pharmacodynamics. Undoubtedly, patients should remain under the medical care of qualified transplantologists, but constant cooperation with a general practitioner and geriatrician would be of added value. Study results show that although most of the elderly kidney recipients have constant contact with their general practitioners, and almost half of them use private care, contribution of the geriatrician to the transplant care system is unsatisfactory, and elderly kidney recipients would expect more extensive outpatient care.
    MeSH term(s) Aged ; Aged, 80 and over ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Kidney Transplantation ; Long-Term Care/methods ; Male ; Middle Aged ; Transplant Recipients
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2018-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2018.04.051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Oscillations in counting statistics

    Wilk, Grzegorz / Wlodarczyk, Zbigniew

    2016  

    Abstract: The very large transverse momenta and large multiplicities available in present LHC experiments on pp collisions allow a much closer look at the corresponding distributions. Some time ago we discussed a possible physical meaning of apparent log-periodic ... ...

    Abstract The very large transverse momenta and large multiplicities available in present LHC experiments on pp collisions allow a much closer look at the corresponding distributions. Some time ago we discussed a possible physical meaning of apparent log-periodic oscillations showing up in p_T distributions (suggesting that the exponent of the observed power-like behavior is complex). In this talk we concentrate on another example of oscillations, this time connected with multiplicity distributions P(N). We argue that some combinations of the experimentally measured values of P(N) (satisfying the recurrence relations used in the description of cascade-stochastic processes in quantum optics) exhibit distinct oscillatory behavior, not observed in the usual Negative Binomial Distributions used to fit data. These oscillations provide yet another example of oscillations seen in counting statistics in many different, apparently very disparate branches of physics further demonstrating the universality of this phenomenon.

    Comment: Invited talk at ISMD2016, Seogwipo, Jeju Island, South Korea, 29.08-02.09.2016, to be published in EPJ Web of Conferences
    Keywords High Energy Physics - Phenomenology ; Nuclear Theory
    Subject code 612
    Publishing date 2016-10-06
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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