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  1. AU="Waalkens-Berendsen, Ine"
  2. AU="Zhang, Wenbo"
  3. AU="Xue, Jumin"
  4. AU="Nampota, Nginache"
  5. AU="de Carvalho, Vinicius S"
  6. AU=Eisen Michael B
  7. AU="Manal S. Selim" AU="Manal S. Selim"
  8. AU="Alturki, Ramadan"
  9. AU="Kluger, Benzi"
  10. AU="Mitchell, Krista"
  11. AU="Oakes, Mary"
  12. AU="Kevill, Dennis N"
  13. AU="Rojas, Almudena"
  14. AU=Dalmau Josep AU=Dalmau Josep
  15. AU="Vaňáčová, Štěpánka"
  16. AU="Hancioglu, Baris"
  17. AU="Scribner, Kim T"
  18. AU="Emanuel Schmassmann"
  19. AU="Patel, Monica"
  20. AU=Passariello Margherita
  21. AU=Saikia Bedangshu
  22. AU="Dion, Dominique"
  23. AU="Magami, Shunsuke"
  24. AU="Wagner, Henrik"

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  1. Artikel ; Online: Follow-up of the re-evaluation of quillaia extract (E 999) as a food additive and safety of the proposed extension of uses.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Degen, Gisela / Engel, Karl-Heinz / Fowler, Paul / Frutos Fernandez, Maria Jose / Gundert-Remy, Ursula / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Mennes, Wim / Moldeus, Peter / Passamonti, Sabina / Shah, Romina / Waalkens-Berendsen, Ine / Wright, Matthew / Cheyns, Karlien / Mirat, Manuela /
    Rincon, Ana Maria / Tard, Alexandra / Zakidou, Panagiota / Fürst, Peter

    EFSA journal. European Food Safety Authority

    2024  Band 22, Heft 2, Seite(n) e8563

    Abstract: Quillaia extract (E 999) was re-evaluated in 2019 by the EFSA Panel on Food Additives and Flavourings (FAF). EFSA derived an acceptable daily intake (ADI) of 3 mg saponins/kg bw per day for E 999. Following a European Commission call for data to submit ... ...

    Abstract Quillaia extract (E 999) was re-evaluated in 2019 by the EFSA Panel on Food Additives and Flavourings (FAF). EFSA derived an acceptable daily intake (ADI) of 3 mg saponins/kg bw per day for E 999. Following a European Commission call for data to submit data to fill the data gaps, the present follow-up opinion assesses data provided by interested business operators (IBOs) to support an amendment of the EU specifications for E 999. Additionally, this opinion deals with the assessment of the proposed extension of use for E 999 in food supplements supplied in a solid and liquid form, excluding food supplements for infants and young children and, as a carrier in botanical nutrients. The Panel concluded that the proposed extension of use, if authorised, could result in an exceedance of the ADI at the maximum of the ranges of the mean for children, adolescents and the elderly, and for all populations at the 95th percentile. An additional proposed extension of use for E 999 to be used as a carrier for glazing agents on entire fresh fruits and vegetables has been received. Since no information on the proposed use levels of E 999 on a saponins content basis has been provided by this applicant, the Panel was not able to evaluate the safety of this extension of use. Considering the technical data submitted, the Panel recommended some modifications of the existing EU specifications for E 999, mainly to lower the limits for lead, mercury and arsenic and to include a maximum limit for cadmium and for calcium oxalate. The Panel also recommended that the limits would be expressed on a saponins basis. The Panel proposed to revise the definition of E 999 to better describe the composition in a qualitative way.
    Sprache Englisch
    Erscheinungsdatum 2024-02-06
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2024.8563
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Re-evaluation of guar gum (E 412) as a food additive in foods for infants below 16 weeks of age and follow-up of its re-evaluation as food additive for uses in foods for all population groups.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Degen, Gisela / Engel, Karl-Heinz / Fowler, Paul / Frutos Fernandez, Maria Jose / Fürst, Peter / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Mennes, Wim / Moldeus, Peter / Passamonti, Sabina / Shah, Romina / Waalkens-Berendsen, Ine / Wright, Matthew / Dusemund, Birgit / Mortensen, Alicja /
    Turck, Dominique / Wölfle, Detlef / Barmaz, Stefania / Mech, Agnieszka / Tard, Alexandra / Gundert-Remy, Ursula

    EFSA journal. European Food Safety Authority

    2024  Band 22, Heft 5, Seite(n) e8748

    Abstract: Guar gum (E 412) was re-evaluated in 2017 by the former EFSA Panel on Food Additives and Nutrient sources added to Food (ANS). As a follow-up to this assessment, the Panel on Food Additives and Flavourings (FAF) was requested to assess the safety of guar ...

    Abstract Guar gum (E 412) was re-evaluated in 2017 by the former EFSA Panel on Food Additives and Nutrient sources added to Food (ANS). As a follow-up to this assessment, the Panel on Food Additives and Flavourings (FAF) was requested to assess the safety of guar gum (E 412) for its uses as food additive in food for infants below 16 weeks of age belonging to food categories 13.1.1 (Infant formulae) and 13.1.5.1 (Dietary foods for infants for special medical purposes and special formulae for infants). In addition, the FAF Panel was requested to address the issues already identified during the re-evaluation of the food additive when used in food for the general population. The process involved the publication of a call for data to allow the interested business operators to provide the requested information to complete the risk assessment. In the response to EFSA requests, one IBO stated that E 412 is not used in food categories 13.1.1 and 13.1.5.1, but it is present in products under food category 13.1.5.2. The Panel concluded that the submitted data are not sufficient to support the safe use of guar gum (E 412) in food for infants (below and above 16 weeks of age) and young children under FC 13.1.1, 13.1.5.1 and 13.1.5.2. Additionally, the Panel concluded that the technical data provided by the IBO support further amendments of the specifications for E 412 laid down in Commission Regulation (EU) No 231/2012.
    Sprache Englisch
    Erscheinungsdatum 2024-05-06
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2024.8748
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Flavouring group evaluation 419 (FGE.419): 2-methyl-1-(2-(5-(p-tolyl)-1H-imidazol-2-yl)piperidin-1-yl)butan-1-one.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Degen, Gisela / Engel, Karl-Heinz / Fowler, Paul J / Frutos Fernandez, Maria Jose / Fürst, Peter / Gundert-Remy, Ursula / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Moldeus, Peter / Passamonti, Sabina / Shah, Romina / Waalkens-Berendsen, Ine / Wright, Matthew / Benigni, Romualdo / Bolognesi, Claudia /
    Chipman, Kevin / Cordelli, Eugenia / Nørby, Karin / Svendsen, Camilla / Carfì, Maria / Gagliardi, Gabriele / Martino, Carla / Multari, Salvatore / Mennes, Wim

    EFSA journal. European Food Safety Authority

    2024  Band 22, Heft 5, Seite(n) e8750

    Abstract: The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of 2-methyl-1-(2-(5-(p-tolyl)-1H-imidazol-2-yl)piperidin-1-yl)butan-1-one [FL-no: 16.134] as a new flavouring substance, in accordance with Regulation (EC) No ... ...

    Abstract The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of 2-methyl-1-(2-(5-(p-tolyl)-1H-imidazol-2-yl)piperidin-1-yl)butan-1-one [FL-no: 16.134] as a new flavouring substance, in accordance with Regulation (EC) No 1331/2008. The substance has not been reported to occur naturally and is chemically synthesised. In food, it is intended to be used as a flavouring substance only in chewing gum. The chronic dietary exposure to [FL-no: 16.134] was estimated to be 45 μg/person per day for a 60-kg adult and 28.4 μg/person per day for a 15-kg 3-year-old child. [FL-no: 16.134] did not show genotoxicity in a bacterial reverse mutation test and an in vitro mammalian cell micronucleus assay. Based on the submitted toxicokinetic and metabolism data, it can be predicted that the flavouring substance is metabolised to innocuous products only. The Panel derived a lower confidence limit of the benchmark dose (BMDL) of 0.71 mg/kg bw per day for a 20% increase in the relative thyroid (including parathyroid) weight observed in a 90-day toxicity study in rats. Based on this BMDL, adequate margins of exposure of 887 and 374 could be calculated for adults and children, respectively. The Panel concluded that there is no safety concern for [FL-no: 16.134], when used as a flavouring substance at the estimated level of dietary exposure, based on the intended use and use levels as specified in Appendix B. The Panel further concluded that the combined exposure to [FL-no: 16.134] from its use as a food flavouring substance and from its presence in toothpaste and mouthwash is also not of safety concern.
    Sprache Englisch
    Erscheinungsdatum 2024-05-06
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2024.8750
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Flavouring Group Evaluation 413 (FGE.413): Naringenin.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Degen, Gisela / Engel, Karl-Heinz / Fowler, Paul J / Frutos Fernandez, Maria José / Fürst, Peter / Gundert-Remy, Ursula / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Moldeus, Peter / Passamonti, Sabina / Shah, Romina / Waalkens-Berendsen, Ine / Wright, Matthew / Benigni, Romualdo / Bolognesi, Claudia /
    Chipman, Kevin / Cordelli, Eugenia / Nørby, Karin / Svendsen, Camilla / Carfí, Maria / Dino, Borana / Gagliardi, Gabriele / Mech, Agnieszka / Multari, Salvatore / Mennes, Wim

    EFSA journal. European Food Safety Authority

    2024  Band 22, Heft 5, Seite(n) e8747

    Abstract: The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of naringenin [FL-no: 16.132] as a new flavouring substance, in accordance with Regulation (EC) No 1331/2008. No other substances with sufficient structural ... ...

    Abstract The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of naringenin [FL-no: 16.132] as a new flavouring substance, in accordance with Regulation (EC) No 1331/2008. No other substances with sufficient structural similarity have been identified in existing FGEs that could be used to support a read-across approach. The information provided on the manufacturing process, the composition and the stability of [FL-no: 16.132] was considered sufficient. From studies carried out with naringenin, the Panel concluded that there is no concern with respect to genotoxicity. The use of naringenin as a flavouring substance at added portions exposure technique (APET) exposure levels is unlikely to pose a risk for drug interaction. For the toxicological evaluation of naringenin, the Panel requested an extended one-generation toxicity study on naringenin, in line with the requirements of the Procedure and to investigate the consequence of a possible endocrine-disrupting activity. The Panel considered that changes in thymus weight, litter size, post-implantation loss and a consistent reduced pup weight in the high-dose F2 generation could not be dismissed and selected therefore, the mid-dose of 1320 mg/kg body weight (bw) per day for the parental males as the no observed adverse effect level (NOAEL) of the study. The exposure estimates for [FL-no: 16.132] (31,500 and 50,000 μg/person per day for children and adults, respectively) were above the threshold of toxicological of concern (TTC) for its structural class (III). Using the NOAEL of 1320 mg/kg bw per day at step A4 of the procedure, margins of exposure (MoE) of 1590 and 630 could be calculated for adults and children, respectively. Based on the calculated MoEs, the Panel concluded that the use of naringenin as a flavouring substance does not raise a safety concern.
    Sprache Englisch
    Erscheinungsdatum 2024-05-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2024.8747
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Flavouring Group Evaluation 21 Revision 6 (FGE.21Rev6): thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical groups 29 and 30.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Degen, Gisela / Engel, Karl-Heinz / Fowler, Paul J / Frutos Fernandez, Maria Jose / Fürst, Peter / Gundert-Remy, Ursula / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Passamonti, Sabina / Moldeus, Peter / Shah, Romina / Waalkens-Berendsen, Ine / Wright, Matthew / Benigni, Romualdo / Bolognesi, Claudia /
    Chipman, Kevin / Cordelli, Eugenia / Nørby, Karin / Svendsen, Camilla / Carfì, Maria / Mennes, Wim

    EFSA journal. European Food Safety Authority

    2023  Band 21, Heft 2, Seite(n) e07777

    Abstract: The Panel on Food additives and Flavourings (FAF) was requested to evaluate the flavouring substances 2,4-dimethyl-3-thiazoline [FL-no: 15.060] and 2-isobutyl-3-thiazoline [FL-no: 15.119] in Flavouring Group Evaluation 21 revision 6 (FGE.21Rev6). FGE ... ...

    Abstract The Panel on Food additives and Flavourings (FAF) was requested to evaluate the flavouring substances 2,4-dimethyl-3-thiazoline [FL-no: 15.060] and 2-isobutyl-3-thiazoline [FL-no: 15.119] in Flavouring Group Evaluation 21 revision 6 (FGE.21Rev6). FGE.21Rev6 deals with 41 flavouring substances of which 39 have been already evaluated to be of no safety concern when based on the MSDI approach. For [FL-no: 15.060 and 15.119], a concern for genotoxicity was raised in FGE.21. Genotoxicity data have been submitted for the supporting substance 4,5-dimethyl-2-isobutyl-3-thiazoline [FL-no: 15.032] evaluated in FGE.76Rev2. The concerns for gene mutations and clastogenicity are ruled out for [FL-no: 15.032] and for the structurally related substances [FL-no: 15.060 and 15.119], but not for aneugenicity. Therefore, the aneugenic potential of [FL-no: 15.060 and 15.119] should be investigated in studies with the individual substances. For [FL-no: 15.054, 15.055, 15.057, 15.079 and 15.135], (more reliable) information on uses and use levels is needed to (re)calculate the mTAMDIs in order to finalise their evaluation. Provided that information is submitted for [FL-no: 15.060 and 15.119] with respect to potential aneugenicity, that would allow evaluation of these substances through the Procedure, also for these two substances, more reliable data on uses and use levels would be required. Upon submission of such data, additional data on toxicity may become necessary for all seven substances. For [FL-no: 15.054, 15.057, 15.079 and 15.135], information on the actual percentages of stereoisomers in the material of commerce based on analytical data should be provided.
    Sprache Englisch
    Erscheinungsdatum 2023-02-13
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2023.7777
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Flavouring Group Evaluation 217 Revision 3 (FGE.217Rev3): consideration of genotoxic potential for α,β-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: lactones.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Degen, Gisela / Engel, Karl-Heinz / Fowler, Paul J / Frutos Fernandez, Maria José / Fürst, Peter / Gundert-Remy, Ursula / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Moldeus, Peter / Passamonti, Sabina / Shah, Romina / Waalkens-Berendsen, Ine / Wright, Matthew / Benigni, Romualdo / Bolognesi, Claudia /
    Chipman, Kevin / Cordelli, Eugenia / Carfì, Maria / Mennes, Wim

    EFSA journal. European Food Safety Authority

    2023  Band 21, Heft 4, Seite(n) e07967

    Abstract: The Panel on Food Additives and Flavourings of the European Food Safety Authority was requested to evaluate the genotoxic potential of four flavouring substances [FL-no: 10.023, 10.030, 10.057 and 13.012] from subgroup 4.1 of FGE.19. For three of these ... ...

    Abstract The Panel on Food Additives and Flavourings of the European Food Safety Authority was requested to evaluate the genotoxic potential of four flavouring substances [FL-no: 10.023, 10.030, 10.057 and 13.012] from subgroup 4.1 of FGE.19. For three of these substances [FL-no: 10.023, 10.030 and 13.012], the concern for genotoxicity has been ruled out in previous revisions of Flavouring Group Evaluation 217 (FGE.217). However, in FGE.217Rev2, a concern for genotoxicity could not be ruled out for 3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3
    Sprache Englisch
    Erscheinungsdatum 2023-04-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2023.7967
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: The assessment of the safety for the consumer of feed additives and additives added to foods of animal origin

    Woutersen, Ruud A. / Waalkens-Berendsen, Ine / Wester, Piet / Rietjens, Ivonne M.C.M.

    Chemical hazards in foods of animal origin ; ISBN: 9789086863266

    2019  

    Abstract: Safe animal feed is important for the health of animals, the safety of the consumer of food of animal origin and for the environment. There is a close link between the safety of animal feed and the foods derived from the animals given this fodder. ... ...

    Abstract Safe animal feed is important for the health of animals, the safety of the consumer of food of animal origin and for the environment. There is a close link between the safety of animal feed and the foods derived from the animals given this fodder. Additives are purposely added to animal feed or to food of animal origin with the aim to improve the quality of the feed and the quality of the food of animal origin. Assessing the safety of feed additives or additives added to food of animal origin requires a multidisciplinary approach to asses all aspects relevant to the intended use of that compound. The principles of the assessment of the safety of the consumer exposed to compounds via food from animal origin are described. An overview is given of the toxicity studies that are used to assess the safety, including the method to derive the safe intake for the consumer based on the outcome of the toxicity studies. The approach is illustrated by four examples of commercially available additives in order to illustrate how regulatory authorities, i.e. the European Food Safety Authority, evaluate the (absence of) potential health effects for consumers.
    Schlagwörter Life Science
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Verlag Wageningen Academic Publishers
    Erscheinungsland nl
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Scientific opinion on Flavouring group evaluation 216 revision 2 (FGE.216Rev2): consideration of the genotoxicity potential of α,β-unsaturated 2-phenyl-2-alkenals from subgroup 3.3 of FGE.19.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Degen, Gisela / Engel, Karl-Heinz / Fowler, Paul J / Frutos Fernandez, Maria Jose / Fürst, Peter / Gundert-Remy, Ursula / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Moldeus, Peter / Passamonti, Sabina / Shah, Romina / Waalkens-Berendsen, Ine / Wright, Matthew / Benigni, Romualdo / Bolognesi, Claudia /
    Chipman, Kevin / Cordelli, Eugenia / Nørby, Karin / Svendsen, Camilla / Carfì, Maria / Martino, Carla / Mennes, Wim

    EFSA journal. European Food Safety Authority

    2022  Band 20, Heft 8, Seite(n) e07420

    Abstract: The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the genotoxic potential of five flavouring substances from subgroup 3.3 of FGE.19, in the Flavouring Group Evaluation 216 (FGE.216). In FGE.216 and in FGE.216Rev1, the CEF ... ...

    Abstract The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the genotoxic potential of five flavouring substances from subgroup 3.3 of FGE.19, in the Flavouring Group Evaluation 216 (FGE.216). In FGE.216 and in FGE.216Rev1, the CEF Panel requested additional genotoxicity data on 2-phenylcrotonaldehyde [FL-no: 05.062], the representative for these five substances. New experimental data on [FL-no: 05.062] were provided and are evaluated in the present revision of FGE.216 (FGE.216Rev2). Based on the new data, the Panel concluded that, for all the five substances, the concerns for gene mutations and clastogenicity are ruled out by the negative results observed in an
    Sprache Englisch
    Erscheinungsdatum 2022-08-17
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2022.7420
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Follow-up of the re-evaluation of polyglycerol esters of fatty acids (E 475) as a food additive.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Engel, Karl-Heinz / Fowler, Paul / Frutos Fernandez, Maria Jose / Gundert-Remy, Ursula / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Mennes, Wim / Moldeus, Peter / Passamonti, Sabina / Shah, Romina / Waalkens-Berendsen, Ine / Wölfle, Detlef / Wright, Matthew / Cheyns, Karlien / Mirat, Manuela /
    Rincon, Ana Maria / Fürst, Peter

    EFSA journal. European Food Safety Authority

    2022  Band 20, Heft 5, Seite(n) e07308

    Abstract: Polyglycerol esters of fatty acids (PEFA, E 475) was re-evaluated in 2017 by the former EFSA Panel on Food Additives and Nutrient sources added to Food (ANS). As a follow-up to this assessment, in this opinion, the Panel on Food Additives and Flavouring ( ...

    Abstract Polyglycerol esters of fatty acids (PEFA, E 475) was re-evaluated in 2017 by the former EFSA Panel on Food Additives and Nutrient sources added to Food (ANS). As a follow-up to this assessment, in this opinion, the Panel on Food Additives and Flavouring (FAF) addresses the data gaps identified to support an amendment of the EU specifications for E 475. The Panel performed a risk assessment of undesirable impurities and constituents potentially present in E 475. The Panel concluded that the maximum limits in the EU specifications for the 4 toxic elements (arsenic, lead, mercury and cadmium) should be lowered based on actual levels in the commercial food additive E 475. The Panel also concluded that maximum limits for erucic acid, 3-monochloropropanediol and glycidyl esters should be included in the EU specifications for E 475. Alternatively, the Panel recommends an amendment of the definition of E 475 to include a requirement that the fats and oils used in the manufacturing of E 475 comply with the respective EU legislation regarding suitability for human consumption. Further, the Panel concluded that there is no need for setting a specification limit for the content of
    Sprache Englisch
    Erscheinungsdatum 2022-05-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2022.7308
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Follow-up of the re-evaluation of glycerol (E 422) as a food additive.

    Younes, Maged / Aquilina, Gabriele / Castle, Laurence / Engel, Karl-Heinz / Fowler, Paul / Frutos Fernandez, Maria Jose / Gundert-Remy, Ursula / Gürtler, Rainer / Husøy, Trine / Manco, Melania / Mennes, Wim / Moldeus, Peter / Passamonti, Sabina / Shah, Romina / Waalkens-Berendsen, Ine / Wölfle, Detlef / Wright, Matthew / Cheyns, Karlien / Mirat, Manuela /
    Rincon, Ana Maria / Fürst, Peter

    EFSA journal. European Food Safety Authority

    2022  Band 20, Heft 6, Seite(n) e07353

    Abstract: Glycerol (E 422) was re-evaluated in 2017 by the former EFSA Panel on Food Additives and Nutrient sources added to Food (ANS). As a follow-up to that assessment, in this opinion, the Panel on Food Additives and Flavourings (FAF) addresses the data gaps ... ...

    Abstract Glycerol (E 422) was re-evaluated in 2017 by the former EFSA Panel on Food Additives and Nutrient sources added to Food (ANS). As a follow-up to that assessment, in this opinion, the Panel on Food Additives and Flavourings (FAF) addresses the data gaps identified to support an amendment of the EU specifications for E 422 in Commission Regulation (EU) No 231/2012. The Panel performed a risk assessment of undesirable impurities present in E 422. The Panel concluded that the maximum limits in the EU specifications for the four toxic elements (arsenic, lead, mercury and cadmium) should be lowered based on actual levels in the commercial food additive E 422. The Panel recommended setting a numerical limit value for acrolein in the specifications for E 422. The potential exposure to free 3-monochloropropanediol at the maximum limit of 0.1 mg/kg, as laid out in the specifications for E 422, does not give rise to a health concern. The Panel recommended to consider modifying the definition of E 422 in Commission Regulation (EU) No 231/2012 indicating that E 422 is obtained only from vegetable oils and fats and undergoes purification processes that involve distillation, and other clean up steps to obtain refined glycerol. Overall, the Panel concluded that the technical data provided support an amendment of the specifications for glycerol (E 422).
    Sprache Englisch
    Erscheinungsdatum 2022-06-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2540248-1
    ISSN 1831-4732 ; 1831-4732
    ISSN (online) 1831-4732
    ISSN 1831-4732
    DOI 10.2903/j.efsa.2022.7353
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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