LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 457

Search options

  1. Book ; Online ; E-Book: Pädiatrische Endokrinologie und Diabetologie

    Hiort, Olaf / Danne, Thomas / Wabitsch, Martin

    (Springer Reference Medizin)

    2020  

    Author's details Olaf Hiort, Thomas Danne, Martin Wabitsch Hrsg
    Series title Springer Reference Medizin
    Keywords Endocrinology  ; Diabetes ; General practice (Medicine) ; Pediatrics
    Language German
    Size 1 Online-Ressource (XIV, 615 Seiten), 22 Illustrationen, Diagramme
    Edition 2. Auflage
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020328208
    ISBN 978-3-662-57309-9 ; 9783662573082 ; 3-662-57309-1 ; 3662573083
    DOI 10.1007/978-3-662-57309-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book ; Online ; E-Book: Adipositas bei Kindern und Jugendlichen

    Wabitsch, Martin / Hebebrand, Johannes / Kiess, Wieland / Reinehr, Thomas / Wiegand, Susanna

    Grundlagen und Klinik

    2022  

    Author's details Martin Wabitsch, Johannes Hebebrand, Wieland Kiess, Thomas Reinehr, Susanne Wiegand Hrsg
    Keywords Electronic books
    Language German
    Size 1 Online-Ressource (XV, 610 Seiten), Illustrationen, Diagramme
    Edition 2. Auflage
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021408134
    ISBN 978-3-662-59216-8 ; 9783662592151 ; 3-662-59216-9 ; 3662592150
    DOI 10.1007/978-3-662-59216-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Book ; Conference proceedings: Developmental biology of gastrointestinal hormones

    Wabitsch, Martin / Posovszky, Carsten

    10th ESPE Advanced Seminar in Developmental Endocrinology, Ulm, June 3-4, 2016

    (Endocrine development ; vol. 32)

    2017  

    Institution European Society for Paediatric Endocrinology
    Event/congress ESPE Advanced Seminar in Developmental Endocrinology (10., 2016, Ulm)
    Author's details volume editors Martin Wabitsch, Carsten Posovszky
    Series title Endocrine development ; vol. 32
    Collection
    Keywords Gastrointestinal Hormones / physiology ; Digestive System / growth & development ; Pediatrics / methods ; Gastrointestinales Hormon ; Physiologie ; Endokrinologie
    Subject Humanphysiologie ; Mensch ; Körperfunktion ; Magen-Darm-Hormon
    Language English
    Size IX, 187 Seiten, Illustrationen
    Publisher Karger
    Publishing place Basel
    Publishing country Switzerland
    Document type Book ; Conference proceedings
    HBZ-ID HT019452433
    ISBN 978-3-318-05973-1 ; 9783318059748 ; 3-318-05973-0 ; 3318059749
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 A 1560 on loan 0 Vormerkungen

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Behandlung der Adipositas in Kindheit und Adoleszenz

    Wabitsch, Martin

    (In: Herpertz, Stephan; de Zwaan, Martina; Zipfel, Stephan (Ed.), Handbuch Essstörungen und Adipositas (S. 543-548). Berlin, Heidelberg: Springer)

    2022  

    Abstract: Meta-Analysen publizierter Studienergebnisse zur Therapie von Übergewicht und Adipositas bei Kindern und Jugendlichen zeigen, dass es wirksame Therapieprogramme gibt. Die praktische Erfahrung lehrt allerdings, dass diese Programme und die ... ...

    Title translation Treatment of obesity in childhood and adolescence (DeepL)
    Series title In: Herpertz, Stephan; de Zwaan, Martina; Zipfel, Stephan (Ed.), Handbuch Essstörungen und Adipositas (S. 543-548). Berlin, Heidelberg: Springer
    Abstract Meta-Analysen publizierter Studienergebnisse zur Therapie von Übergewicht und Adipositas bei Kindern und Jugendlichen zeigen, dass es wirksame Therapieprogramme gibt. Die praktische Erfahrung lehrt allerdings, dass diese Programme und die zugrundeliegenden Behandlungskonzepte nur von einer Minderheit der Betroffenen angenommen werden. Der Behandlungserfolg wirksamer Therapieprogramme kann individuell sehr unterschiedlich sein. Zudem ist eine Abhängigkeit des Behandlungserfolgs vom anbietenden Behandlungszentrum bekannt. Es wird daher empfohlen, die aktuellen therapeutischen Bemühungen weiter zu evaluieren und schrittweise zu verbessern. Die Ausführungen fassen den aktuellen Kenntnisstand und die Empfehlungen der Fachgesellschaften zusammen, die auf der Basis der vorhandenen Studienergebnisse und der Expertise einer multidisziplinären Arbeitsgruppe entwickelt wurden. (c) Der/die Autor(en), exklusiv lizenziert durch Springer-Verlag GmbH, DE, ein Teil von Springer Nature
    Keywords Adipositas ; Behavior Therapy ; Goals ; Obesity ; Pediatrics ; Pädiatrie ; Therapie ; Training ; Treatment ; Verhaltenstherapie ; Ziele
    Language German
    Document type Article
    DOI 10.1007/978-3-662-63544-5_69
    Database PSYNDEX

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Book: Adipositas bei Kindern und Jugendlichen

    Wabitsch, Martin

    Grundlagen und Klinik ; mit 40 Tabellen

    2005  

    Author's details Martin Wabitsch ... (Hrsg.)
    Keywords Kind ; Fettsucht ; Jugend
    Subject Adipositas ; Fettleibigkeit ; Korpulenz ; Obesität ; Obesity ; Jugend ; Jugendalter ; Jugendlicher ; Teenager ; Kindheit ; Kindesalter ; Kindschaft ; Kinder
    Language German
    Size XV, 443 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    Note Teilw. als Printed-on-demand-Ausgabe mit neuerem Erscheinungsjahr
    HBZ-ID HT014120134
    ISBN 3-540-01251-6 ; 978-3-540-01251-1
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 3929 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Adipositas bei Kindern – die Rolle des Hungerhormons Leptin

    Wabitsch, Martin

    Ernährung & Medizin

    (Hunger: Regulation und Auswirkungen)

    2021  Volume 36, Issue 04, Page(s) 169–171

    Abstract: Anlässlich der 6. Deutschen Hormonwoche, die von der Deutschen Gesellschaft für Endokrinologie e. V. (DGE) vom 18. bis 25. September 2021 ausgerichtet wurde, gab Prof. Dr. Martin Wabitsch vom Universitätsklinikum Ulm einen Überblick über den Einfluss von ...

    Series title Hunger: Regulation und Auswirkungen
    Abstract Anlässlich der 6. Deutschen Hormonwoche, die von der Deutschen Gesellschaft für Endokrinologie e. V. (DGE) vom 18. bis 25. September 2021 ausgerichtet wurde, gab Prof. Dr. Martin Wabitsch vom Universitätsklinikum Ulm einen Überblick über den Einfluss von Leptin im Zusammenhang mit kindlicher Adipositas.
    Language German
    Publishing date 2021-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2133391-9
    ISSN 1438-9002 ; 1439-1635
    ISSN (online) 1438-9002
    ISSN 1439-1635
    DOI 10.1055/a-1393-1835
    Database Thieme publisher's database

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book: Metabolic syndrome and obesity in childhood and adolescence

    Kiess, Wieland / Wabitsch, Martin / Maffeis, Claudio / Sharma, Arya M.

    9 tables

    (Pediatric and adolescent medicine ; 19)

    2015  

    Author's details vol. ed. Wieland Kiess ; Martin Wabitsch ; Claudio Maffeis ; Arya M. Sharma
    Series title Pediatric and adolescent medicine ; 19
    Collection
    Keywords Pediatric Obesity ; Adolescent ; Child ; Metabolic Syndrome X ; Pediatrics ; Kind ; Jugend ; Fettsucht ; Metabolisches Syndrom
    Subject Adipositas ; Fettleibigkeit ; Korpulenz ; Obesität ; Obesity ; Jugend ; Jugendalter ; Jugendlicher ; Teenager ; Kindheit ; Kindesalter ; Kindschaft ; Kinder
    Language English
    Size IX, 199 S. : Ill., graph. Darst., 26 cm
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    Note Literaturangaben
    HBZ-ID HT018570588
    ISBN 978-3-318-02798-3 ; 3-318-02798-7 ; 9783318027990 ; 3318027995
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 865 available for loan (reading room) Lesesaal EG

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Effects of allicin on human Simpson-Golabi-Behmel syndrome cells in mediating browning phenotype.

    Ali, Uzair / Wabitsch, Martin / Tews, Daniel / Colitti, Monica

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1141303

    Abstract: Introduction: Obesity is a major health problem because it is associated with increased risk of cardiovascular disease, diabetes, hypertension, and some cancers. Strategies to prevent or reduce obesity focus mainly on the possible effects of natural ... ...

    Abstract Introduction: Obesity is a major health problem because it is associated with increased risk of cardiovascular disease, diabetes, hypertension, and some cancers. Strategies to prevent or reduce obesity focus mainly on the possible effects of natural compounds that can induce a phenotype of browning adipocytes capable of releasing energy in the form of heat. Allicin, a bioactive component of garlic with numerous pharmacological functions, is known to stimulate energy metabolism.
    Methods: In the present study, the effects of allicin on human Simpson-Golabi-Behmel Syndrome (SGBS) cells were investigated by quantifying the dynamics of lipid droplets (LDs) and mitochondria, as well as transcriptomic changes after six days of differentiation.
    Results: Allicin significantly promoted the reduction in the surface area and size of LDs, leading to the formation of multilocular adipocytes, which was confirmed by the upregulation of genes related to lipolysis. The increase in the number and decrease in the mean aspect ratio of mitochondria in allicin-treated cells indicate a shift in mitochondrial dynamics toward fission. The structural results are confirmed by transcriptomic analysis showing a significant arrangement of gene expression associated with beige adipocytes, in particular increased expression of T-box transcription factor 1 (TBX1), uncoupling protein 1 (UCP1), PPARG coactivator 1 alpha (PPARGC1A), peroxisome proliferator-activated receptor alpha (PPARA), and OXPHOS-related genes. The most promising targets are nuclear genes such as retinoid X receptor alpha (RXRA), retinoid X receptor gamma (RXRG), nuclear receptor subfamily 1 group H member 3 (NR1H3), nuclear receptor subfamily 1 group H member 4 (NR1H4), PPARA, and oestrogen receptor 1 (ESR1).
    Discussion: Transcriptomic data and the network pharmacology-based approach revealed that genes and potential targets of allicin are involved in ligand-activated transcription factor activity, intracellular receptor signalling, regulation of cold-induced thermogenesis, and positive regulation of lipid metabolism. The present study highlights the potential role of allicin in triggering browning in human SGBS cells by affecting the LD dynamics, mitochondrial morphology, and expression of brown marker genes. Understanding the potential targets through which allicin promotes this effect may reveal the underlying signalling pathways and support these findings.
    MeSH term(s) Humans ; Adipocytes, Brown/metabolism ; Phenotype ; Obesity/metabolism ; Transcription Factors/metabolism
    Chemical Substances allicin (3C39BY17Y6) ; Transcription Factors
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1141303
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Gastrointestinal Endocrinology in Bariatric Surgery.

    Wabitsch, Martin

    Endocrine development

    2017  Volume 32, Page(s) 124–138

    Abstract: The long-lasting weight-reducing effect of bariatric surgical procedures cannot simply be explained by the malabsorption of nutrients and the subsequent energy deficit due to this malabsorption. Clinical studies have shown that the reorganization of the ... ...

    Abstract The long-lasting weight-reducing effect of bariatric surgical procedures cannot simply be explained by the malabsorption of nutrients and the subsequent energy deficit due to this malabsorption. Clinical studies have shown that the reorganization of the anatomy of the gut and the subsequent alterations of gastrointestinal physiology have a large impact on the secretion and function of gastrointestinal hormones, which regulate hunger and satiety. These changes have been named the BRAVE effect: <under>b</under>ile flow alteration, <under>r</under>eduction of gastric size, <under>a</under>natomical gut rearrangement and altered flow of nutrients, <under>v</under>agal manipulation, and <under>e</under>nteric gut modulation. In addition, the metabolic improvements, for example, increased insulin secretion and improved glucose sensitivity after bariatric surgery cannot simply be explained by the weight loss achieved by the operation. Several metabolic improvements occur directly after bariatric surgery even before significant weight loss has occurred. Clinical studies revealed that the altered gastrointestinal physiology and the postoperative profile of gastrointestinal hormones are responsible for these metabolic alterations. Further insights into the changes of gastrointestinal hormone profiles before and after bariatric surgery may open new ways to prevent the surgical procedure and probably obtain equivalent results by nutraceuticals.
    Language English
    Publishing date 2017
    Publishing country Switzerland
    Document type Journal Article
    ISSN 1662-2979 ; 1421-7082
    ISSN (online) 1662-2979
    ISSN 1421-7082
    DOI 10.1159/000475735
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Gastrointestinal Hormones Induced the Birth of Endocrinology.

    Wabitsch, Martin

    Endocrine development

    2017  Volume 32, Page(s) 1–7

    Abstract: The physiological studies by British physiologists William Maddock Bayliss and Ernest Henry Starling, at the beginning of the last century, demonstrated the existence of specific messenger molecules (hormones) circulating in the blood that regulate the ... ...

    Abstract The physiological studies by British physiologists William Maddock Bayliss and Ernest Henry Starling, at the beginning of the last century, demonstrated the existence of specific messenger molecules (hormones) circulating in the blood that regulate the organ function and physiological mechanisms. These findings led to the concept of endocrinology. The first 2 hormones were secretin, discovered in 1902, and gastrin, discovered in 1905. Both hormones that have been described are produced in the gut. This chapter summarizes the history around the discovery of these 2 hormones, which is perceived as the birth of endocrinology. It is noteworthy that after the discovery of these 2 gastrointestinal hormones, many other hormones were detected outside the gut, and thereafter gut hormones faded from both the clinical and scientific spotlight. Only recently, the clinical importance of the gut as the body's largest endocrine organ producing a large variety of hormones has been realized. Gastrointestinal hormones are essential regulators of metabolism, growth, development and behavior and are therefore the focus of a modern pediatric endocrinologist.
    Language English
    Publishing date 2017
    Publishing country Switzerland
    Document type Journal Article
    ISSN 1662-2979 ; 1421-7082
    ISSN (online) 1662-2979
    ISSN 1421-7082
    DOI 10.1159/000475726
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top