Article ; Online: Development of a membrane-disruption assay using phospholipid vesicles as a proxy for the detection of cellular membrane degradation.
Toxicon: X
2024 Volume 22, Page(s) 100197
Abstract: Snakebite envenoming is a global health issue that affects millions of people worldwide, and that causes morbidity rates surpassing 450,000 individuals annually. Patients suffering from snakebite morbidities may experience permanent disabilities such as ... ...
| Abstract | Snakebite envenoming is a global health issue that affects millions of people worldwide, and that causes morbidity rates surpassing 450,000 individuals annually. Patients suffering from snakebite morbidities may experience permanent disabilities such as pain, blindness and amputations. The (local) tissue damage that causes these life-long morbidities is the result of cell- and tissue-damaging toxins present in the venoms. These compounds belong to a variety of toxin classes and may affect cells in various ways, for example, by affecting the cell membrane. In this study, we have developed a high-throughput |
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| Language | English |
| Publishing date | 2024-04-07 |
| Publishing country | England |
| Document type | Journal Article |
| ISSN | 2590-1710 |
| ISSN (online) | 2590-1710 |
| DOI | 10.1016/j.toxcx.2024.100197 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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