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  1. Book ; Thesis: Strategisches Management in der österreichischen Agrarwirtschaft

    Wagner, Walter

    wie gut ist es um das strategische Management österreichischer agrarischer Kooperationsbetriebe bestellt?

    (Publikationen der Universität für Bodenkultur Wien)

    2017  

    Title translation Analyse des strategischen Managements mithilfe eines ausgewählten operationalisierten Strategiemodells unter Anwendung des analytischen Hierarchieprozesses bei agrarischen Kooperationen in Österreich
    Author's details Walter Wagner
    Series title Publikationen der Universität für Bodenkultur Wien
    Keywords Österreich ; Agrarökonomie ; Unternehmenskooperation ; Strategisches Management
    Subject Managementstrategie ; Managementkonzept ; Unternehmensstrategie ; Überbetriebliche Zusammenarbeit ; Unternehmen ; Unternehmenszusammenarbeit ; Zwischenbetriebliche Kooperation ; Zwischenbetriebliche Zusammenarbeit ; Internationale Unternehmenskooperation ; Agrarökonomik ; Landwirtschaft
    Language German
    Size 191 Seiten, Diagramme, 21 cm x 15 cm, 320 g
    Publisher Guthmann-Peterson
    Publishing place Wien
    Publishing country Austria
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität für Bodenkultur Wien, 2017
    Note Originaltitel der Dissertation: Analyse des strategischen Managements mithilfe eines ausgewählten operationalisierten Strategiemodells unter Anwendung des analytischen Hierarchieprozesses bei agrarischen Kooperationen in Österreich
    HBZ-ID HT019607770
    ISBN 978-3-900782-75-7 ; 3-900782-75-X
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    188/164 available for loan (reading room) Freihandmagazin (U1)

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  2. Article: How to Translate DNA Methylation Biomarkers Into Clinical Practice.

    Wagner, Wolfgang

    Frontiers in cell and developmental biology

    2022  Volume 10, Page(s) 854797

    Abstract: Recent advances in sequencing technologies provide unprecedented opportunities for epigenetic biomarker development. Particularly the DNA methylation pattern-which is modified at specific sites in the genome during cellular differentiation, aging, and ... ...

    Abstract Recent advances in sequencing technologies provide unprecedented opportunities for epigenetic biomarker development. Particularly the DNA methylation pattern-which is modified at specific sites in the genome during cellular differentiation, aging, and disease-holds high hopes for a wide variety of diagnostic applications. While many epigenetic biomarkers have been described, only very few of them have so far been successfully translated into clinical practice and almost exclusively in the field of oncology. This discrepancy might be attributed to the different demands of either publishing a new finding or establishing a standardized and approved diagnostic procedure. This is exemplified for epigenetic leukocyte counts and epigenetic age-predictions. To ease later clinical translation, the following hallmarks should already be taken into consideration when designing epigenetic biomarkers: 1) Identification of best genomic regions, 2) pre-analytical processing, 3) accuracy of DNA methylation measurements, 4) identification of confounding parameters, 5) accreditation as diagnostic procedure, 6) standardized data analysis, 7) turnaround time, and 8) costs and customer requirements. While the initial selection of relevant genomic regions is usually performed on genome wide DNA methylation profiles, it might be advantageous to subsequently establish targeted assays that focus on specific genomic regions. Development of an epigenetic biomarker for clinical application is a long and cumbersome process that is only initiated with the identification of an epigenetic signature.
    Language English
    Publishing date 2022-02-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.854797
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice

    Waskow, Claudia / Wagner, Wolfgang

    Clinical epigenetics, 10:67

    2018  

    Abstract: BACKGROUND: Transplantation of human hematopoietic stem cells into immunodeficient mice provides a powerful in vivo model system to gain functional insights into hematopoietic differentiation. So far, it remains unclear if epigenetic changes of normal ... ...

    Institution Leibniz-Institut für Alternsforschung
    Abstract BACKGROUND: Transplantation of human hematopoietic stem cells into immunodeficient mice provides a powerful in vivo model system to gain functional insights into hematopoietic differentiation. So far, it remains unclear if epigenetic changes of normal human hematopoiesis are recapitulated upon engraftment into such “humanized mice.” Mice have a much shorter life expectancy than men, and therefore, we hypothesized that the xenogeneic environment might greatly accelerate the epigenetic clock. RESULTS: We demonstrate that genome-wide DNA methylation patterns of normal human hematopoietic development are indeed recapitulated upon engraftment in mice—particularly those of normal early B cell progenitor cells. Furthermore, we tested three epigenetic aging signatures, and none of them indicated that the murine environment accelerated age-associated DNA methylation changes. CONCLUSIONS: Epigenetic changes of human hematopoietic development are recapitulated in the murine transplantation model, whereas epigenetic aging is not accelerated by the faster aging environment and seems to occur in the cell intrinsically.
    Keywords Aging ; DNA methylation ; Epigenetic ; Hematopoiesis ; Humanized mice ; Transplantation
    Language English
    Document type Article
    Database Repository for Life Sciences

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  4. Book ; Audio / Video ; Thesis: Einfluss des cytosolischen Prion-Proteins auf die Zellmorphologie und zelluläre Aspekte der Prionpathogenese

    Wagner, Wibke

    2011  

    Author's details von Wibke Wagner
    Language German
    Size 1 CD-ROM, 12 cm
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 2011
    Accompanying material Beil. ([2] S.)
    HBZ-ID HT017180895
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2012 MO 212 order for loan Magazin

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  5. Book ; Online: Der Volksgerichtshof im nationalsozialistischen Staat. Mit einem Forschungsbericht für die Jahre 1975 bis 2010

    Wagner, Walter

    2011  

    Keywords History of Germany ; Modern history, 1453 ; Political science (General) ; Law in general. Comparative and uniform law. Jurisprudence
    Size 1 electronic resource (1024 p.)
    Publisher De Gruyter
    Document type Book ; Online
    Note German ; Open Access
    HBZ-ID HT020097631
    ISBN 9783486705591 ; 3486705598
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article: Lehren aus der Pandemie. Bilanz und Ausblick

    Wagner, Wolfgang

    Dr. med. Mabuse

    2023  Volume 48, Issue 260, Page(s) 20

    Language German
    Document type Article
    ZDB-ID 796434-1
    ISSN 0173-430X
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2548: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Lehren aus der Pandemie. Bilanz und Ausblick

    Wagner, Wolfgang

    Dr. med. Mabuse

    2023  Volume 48, Issue 260, Page(s) 20

    Language German
    Document type Article
    ZDB-ID 796434-1
    ISSN 0173-430X
    Database Current Contents Medicine

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  8. Article: Herkulesaufgaben. Lauterbachs To-Do-Liste ist umfangreich

    Wagner, Wolfgang

    Dr. med. Mabuse

    2023  Volume 48, Issue 259, Page(s) 22

    Language German
    Document type Article
    ZDB-ID 796434-1
    ISSN 0173-430X
    Database Current Contents Medicine

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  9. Article: Pflege und Kliniken am Limit. – auch nach Lauterbachs Reformen

    Wagner, Wolfgang

    Dr. med. Mabuse

    2023  Volume 48, Issue 261, Page(s) 22

    Language German
    Document type Article
    ZDB-ID 796434-1
    ISSN 0173-430X
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

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  10. Article ; Online: José Francisco M. Salomão - President of the ISPN 2019-2021.

    Wagner, Wolfgang

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2021  Volume 37, Issue 11, Page(s) 3285–3292

    Language English
    Publishing date 2021-08-11
    Publishing country Germany
    Document type Letter
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-021-05311-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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