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  1. Article: Cardiopulmonary Exercise Testing after Surgical Repair of Tetralogy of Fallot-Does Modality Matter?

    Leonardi, Benedetta / Sollazzo, Fabrizio / Gentili, Federica / Bianco, Massimiliano / Pomiato, Elettra / Kikina, Stefani Silva / Wald, Rachel Maya / Palmieri, Vincenzo / Secinaro, Aurelio / Calcagni, Giulio / Butera, Gianfranco / Giordano, Ugo / Cafiero, Giulia / Drago, Fabrizio

    Journal of clinical medicine

    2024  Volume 13, Issue 5

    Abstract: Background: Despite a successful repair of tetralogy of Fallot (rToF) in childhood, residual lesions are common and can contribute to impaired exercise capacity. Although both cycle ergometer and treadmill protocols are often used interchangeably these ... ...

    Abstract Background: Despite a successful repair of tetralogy of Fallot (rToF) in childhood, residual lesions are common and can contribute to impaired exercise capacity. Although both cycle ergometer and treadmill protocols are often used interchangeably these approaches have not been directly compared. In this study we examined cardiopulmonary exercise test (CPET) measurements in rToF.
    Methods: Inclusion criteria were clinically stable rToF patients able to perform a cardiac magnetic resonance imaging (CMR) and two CPET studies, one on the treadmill (incremental Bruce protocol) and one on the cycle ergometer (ramped protocol), within 12 months. Demographic, surgical and clinical data; functional class; QRS duration; CMR measures; CPET data and international physical activity questionnaire (IPAQ) scores of patients were collected.
    Results: Fifty-seven patients were enrolled (53% male, 20.5 ± 7.8 years at CPET). CMR measurements included a right ventricle (RV) end-diastolic volume index of 119 ± 22 mL/m
    Conclusions: The majority of CPET measurements differed according to the modality of testing, with the exception being the VE/VCO
    Language English
    Publishing date 2024-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13051192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cardiac Complications in Pregnant Women With Isolated Mitral Stenosis and Their Association With Echocardiographic Changes During Pregnancy.

    Wichert-Schmitt, Barbara / Steckham, Katherine Elizabeth / Pfaller, Birgit / Colman, Jack Marc / Wald, Rachel Maya / Sermer, Mathew / Mason, Jennifer / Siu, Samuel Chi Bun / Silversides, Candice Kristeen

    The American journal of cardiology

    2021  Volume 158, Page(s) 81–89

    Abstract: In women with mitral stenosis (MS), mitral valve gradients and right ventricular systolic pressure (RVSP) can increase in response to the physiologic stress of pregnancy. The prognostic significance of these echocardiographic changes has not been well ... ...

    Abstract In women with mitral stenosis (MS), mitral valve gradients and right ventricular systolic pressure (RVSP) can increase in response to the physiologic stress of pregnancy. The prognostic significance of these echocardiographic changes has not been well studied. Pregnancy outcomes and serial echocardiograms were collected in women with MS prospectively recruited as part of a larger study on pregnancy outcomes. Third trimester echocardiograms were compared with baseline echocardiograms. Changes in mitral valve area (MVA), transmitral mean gradient (MG), and RVSP during pregnancy and their relationship to adverse cardiac events (CE) were examined. Fifty-six pregnancies in 47 women with MS were included. The MVA did not change during pregnancy (1.6 ± 0.6 cm
    MeSH term(s) Adult ; Blood Pressure ; Echocardiography ; Female ; Humans ; Mitral Valve Stenosis/complications ; Mitral Valve Stenosis/diagnostic imaging ; Mitral Valve Stenosis/physiopathology ; Pregnancy ; Pregnancy Complications, Cardiovascular/diagnostic imaging ; Pregnancy Complications, Cardiovascular/physiopathology ; Retrospective Studies ; Ventricular Function, Right/physiology
    Language English
    Publishing date 2021-09-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2021.07.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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