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  1. Article ; Online: Coronavirus disease 2019 (Covid-19) presenting as purulent fulminant myopericarditis and cardiac tamponade: A case report and literature review.

    Khatri, Akshay / Wallach, Frances

    Heart & lung : the journal of critical care

    2020  Volume 49, Issue 6, Page(s) 858–863

    Abstract: The vast majority of patients in the ongoing coronavirus Disease 2019 (Covid-19) pandemic primarily present with severe respiratory illness. We report a Covid-19 patient who presented with findings of acute coronary syndrome and was found to have ... ...

    Abstract The vast majority of patients in the ongoing coronavirus Disease 2019 (Covid-19) pandemic primarily present with severe respiratory illness. We report a Covid-19 patient who presented with findings of acute coronary syndrome and was found to have purulent fulminant myopericarditis and cardiac tamponade. We compare our case to the previously reported instances of Covid-19-associated myocarditis. Through review of the available literature, we also highlight the potential mechanisms of cardiac injury in Covid-19. We hope to increase awareness amongst clinicians about this unusual presentation of Covid-19.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Cardiac Tamponade/diagnosis ; Cardiac Tamponade/physiopathology ; Cardiac Tamponade/therapy ; Cardiac Tamponade/virology ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Fatal Outcome ; Humans ; Male ; Middle Aged ; Myocarditis/diagnosis ; Myocarditis/physiopathology ; Myocarditis/therapy ; Myocarditis/virology ; Pandemics ; Pericardiocentesis ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 193129-5
    ISSN 1527-3288 ; 0147-9563
    ISSN (online) 1527-3288
    ISSN 0147-9563
    DOI 10.1016/j.hrtlng.2020.06.003
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    Zs.A 1035: Show issues Location:
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  2. Article ; Online: Letter to the Editor: Immunogenicity After the Third Dose of COVID-19 Vaccine in Cardiac Transplantation.

    Rahman, Afsana / Golombeck, David / Malhame, Kathryn / Rossi, Dora / Wallach, Frances / Avila, Maria / Maybaum, Simon

    Transplantation

    2023  Volume 107, Issue 12, Page(s) e370–e372

    MeSH term(s) Humans ; Antibodies, Viral ; COVID-19/prevention & control ; COVID-19 Vaccines ; Heart Transplantation/adverse effects
    Chemical Substances Antibodies, Viral ; COVID-19 Vaccines
    Language English
    Publishing date 2023-10-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004843
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  3. Article ; Online: Coronavirus disease 2019 and extra-pulmonary tuberculosis co-infection - A case report and review of literature.

    Gerstein, Shawn / Khatri, Akshay / Roth, Nitzan / Wallach, Frances

    Journal of clinical tuberculosis and other mycobacterial diseases

    2021  Volume 22, Page(s) 100213

    Abstract: The Coronavirus disease 2019 (COVID-19) pandemic continues to cause significant global morbidity and mortality, leading to the need to study the course of the disease in different clinical circumstances and patient populations. While co-infection between ...

    Abstract The Coronavirus disease 2019 (COVID-19) pandemic continues to cause significant global morbidity and mortality, leading to the need to study the course of the disease in different clinical circumstances and patient populations. While co-infection between COVID-19 and many pathogens has been reported, there has been limited published research regarding co-infection with
    Language English
    Publishing date 2021-01-07
    Publishing country England
    Document type Case Reports
    ISSN 2405-5794
    ISSN (online) 2405-5794
    DOI 10.1016/j.jctube.2021.100213
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  4. Article ; Online: Secondary syphilis with alopecia and ocular manifestation.

    Chang, Kai-Ming / Nadi, Lemar / Wallach, Frances

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2021  Volume 54, Issue 4, Page(s) 758–759

    MeSH term(s) Adult ; Alopecia/complications ; Alopecia/diagnosis ; Alopecia/pathology ; Dermis/pathology ; Eye ; HIV ; HIV Infections/complications ; Humans ; Male ; Syphilis/complications ; Syphilis/diagnosis ; Syphilis/pathology ; Uveitis/complications ; Uveitis/diagnosis ; Uveitis/pathology
    Language English
    Publishing date 2021-01-05
    Publishing country England
    Document type Letter
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    DOI 10.1016/j.jmii.2020.12.015
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  5. Article ; Online: A case of severe COVID-19 despite full vaccination with mRNA-1273 SARS-CoV-2 vaccine (Moderna) in a kidney transplant recipient.

    Chang, Kai-Ming / Berlinrut, Ilan / Wallach, Frances R

    Transplant infectious disease : an official journal of the Transplantation Society

    2021  Volume 23, Issue 5, Page(s) e13710

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Humans ; Kidney Transplantation/adverse effects ; RNA, Messenger ; SARS-CoV-2 ; Vaccination
    Chemical Substances COVID-19 Vaccines ; RNA, Messenger
    Language English
    Publishing date 2021-08-16
    Publishing country Denmark
    Document type Letter ; Comment
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.13710
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    Zs.A 5100: Show issues Location:
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  6. Article: Coronavirus disease 2019 (Covid-19) presenting as purulent fulminant myopericarditis and cardiac tamponade: A case report and literature review

    Khatri, Akshay / Wallach, Frances

    Heart Lung

    Abstract: The vast majority of patients in the ongoing coronavirus Disease 2019 (Covid-19) pandemic primarily present with severe respiratory illness. We report a Covid-19 patient who presented with findings of acute coronary syndrome and was found to have ... ...

    Abstract The vast majority of patients in the ongoing coronavirus Disease 2019 (Covid-19) pandemic primarily present with severe respiratory illness. We report a Covid-19 patient who presented with findings of acute coronary syndrome and was found to have purulent fulminant myopericarditis and cardiac tamponade. We compare our case to the previously reported instances of Covid-19-associated myocarditis. Through review of the available literature, we also highlight the potential mechanisms of cardiac injury in Covid-19. We hope to increase awareness amongst clinicians about this unusual presentation of Covid-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #591848
    Database COVID19

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  7. Article ; Online: Coronavirus disease 2019 (Covid-19) presenting as purulent fulminant myopericarditis and cardiac tamponade

    Khatri, Akshay / Wallach, Frances

    Heart & Lung

    A case report and literature review

    2020  Volume 49, Issue 6, Page(s) 858–863

    Keywords Critical Care and Intensive Care Medicine ; Pulmonary and Respiratory Medicine ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 193129-5
    ISSN 1527-3288 ; 0147-9563
    ISSN (online) 1527-3288
    ISSN 0147-9563
    DOI 10.1016/j.hrtlng.2020.06.003
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Mucormycosis after Coronavirus disease 2019 infection in a heart transplant recipient - Case report and review of literature.

    Khatri, Akshay / Chang, Kai-Ming / Berlinrut, Ilan / Wallach, Frances

    Journal de mycologie medicale

    2021  Volume 31, Issue 2, Page(s) 101125

    Abstract: Mucormycosis is an invasive fungal infection (IFI) due to several species of saprophytic fungi, occurring in patients with underlying co-morbidities (including organ transplantation). During the ongoing Coronavirus disease 2019 (COVID-19) pandemic, there ...

    Abstract Mucormycosis is an invasive fungal infection (IFI) due to several species of saprophytic fungi, occurring in patients with underlying co-morbidities (including organ transplantation). During the ongoing Coronavirus disease 2019 (COVID-19) pandemic, there have been increasing reports of bacterial and fungal co-infections occurring in COVID-19 patients, including COVID-19 associated pulmonary aspergillosis (CAPA). We describe a case of mucormycosis occurring after COVID-19, in an individual who received a recent heart transplant for severe heart failure. Two months after heart transplant, our patient developed upper respiratory and systemic symptoms and was diagnosed with COVID-19. He was managed with convalescent plasma therapy and supportive care. Approximately three months after COVID-19 diagnosis, he developed cutaneous mucormycosis at an old intravascular device site. He underwent extensive surgical interventions, combined with broad-spectrum antifungal therapy. Despite the aggressive therapeutic measures, he died after a prolonged hospital stay. In this case report, we also review the prior well-reported cases of mucormycosis occurring in COVID-19 patients and discuss potential mechanisms by which COVID-19 may predispose to IFIs. Similar to CAPA, mucormycosis with COVID-19 may need to be evaluated as an emerging disease association. Clinicians should be vigilant to evaluate for invasive fungal infections such as mucormycosis in patients with COVID-19 infection.
    MeSH term(s) Aged ; Anti-Infective Agents/therapeutic use ; Bacteremia/complications ; Bacteremia/drug therapy ; Bacteremia/microbiology ; COVID-19/complications ; COVID-19/therapy ; Catheter-Related Infections/drug therapy ; Catheter-Related Infections/etiology ; Coinfection/drug therapy ; Coinfection/microbiology ; Combined Modality Therapy ; Contraindications, Drug ; Debridement ; Dermatomycoses/drug therapy ; Dermatomycoses/etiology ; Disease Susceptibility ; Fatal Outcome ; Heart Failure/surgery ; Heart Transplantation ; Humans ; Hydroxychloroquine/therapeutic use ; Immunization, Passive ; Immunosuppressive Agents/adverse effects ; Immunosuppressive Agents/therapeutic use ; Intra-Aortic Balloon Pumping/instrumentation ; Invasive Fungal Infections/complications ; Invasive Fungal Infections/drug therapy ; Male ; Mucormycosis/complications ; Mucormycosis/drug therapy ; Mucormycosis/microbiology ; Negative-Pressure Wound Therapy ; Opportunistic Infections/complications ; Opportunistic Infections/drug therapy ; Opportunistic Infections/microbiology ; Postoperative Complications/drug therapy ; Postoperative Complications/etiology ; Postoperative Complications/microbiology ; Postoperative Complications/virology ; Rhizopus/isolation & purification ; Surgical Wound Infection/complications ; Surgical Wound Infection/drug therapy ; Surgical Wound Infection/microbiology ; Surgical Wound Infection/surgery ; COVID-19 Serotherapy
    Chemical Substances Anti-Infective Agents ; Immunosuppressive Agents ; Hydroxychloroquine (4QWG6N8QKH)
    Language English
    Publishing date 2021-04-02
    Publishing country France
    Document type Case Reports
    ZDB-ID 1067006-3
    ISSN 1773-0449 ; 1156-5233
    ISSN (online) 1773-0449
    ISSN 1156-5233
    DOI 10.1016/j.mycmed.2021.101125
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    Zs.A 3148: Show issues Location:
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  9. Article: "We are Getting Those Old People Things." Polypharmacy Management and Medication Adherence Among Adult HIV Patients with Multiple Comorbidities: A Qualitative Study.

    Bevilacqua, Kristin G / Brinkley, Charell / McGowan, Joseph / Wallach, Frances / Schwartz, Rebecca M

    Patient preference and adherence

    2022  Volume 16, Page(s) 2773–2780

    Abstract: Introduction: Improvements in treatment have led to a growing population of older adults living with HIV. As this population ages, polypharmacy, or the use of more than five medications, may become more common among people living with HIV (PLWH).: ... ...

    Abstract Introduction: Improvements in treatment have led to a growing population of older adults living with HIV. As this population ages, polypharmacy, or the use of more than five medications, may become more common among people living with HIV (PLWH).
    Methods: Two qualitative focus groups (N=7, N=8) were conducted among a sample of patients who participated in a larger study regarding differential medication adherence. Open-ended questions and probes focused on barriers and facilitators to multiple medication management as well as differential adherence.
    Results: Overall, patients were able to manage their polypharmacy. Social support facilitated adherence while long-term antiretroviral (ARV) use, medication-specific requirements and emotional fatigue were barriers to management. A small number of participants reported differential adherence that prioritized non-HIV medications over ARVs due to more immediate effects of non-adherence.
    Discussion: Findings suggest that PLWH have learned to manage their polypharmacy, but still face significant challenges adhering to multiple medications in the long-term. Future research may focus on the emotional toll of long-term ARV use and how patients' own management strategies may be leveraged to promote adherence.
    Language English
    Publishing date 2022-10-11
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2455848-5
    ISSN 1177-889X
    ISSN 1177-889X
    DOI 10.2147/PPA.S382005
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  10. Article ; Online: Toward a Test Protocol for Surface Decontamination Using a Mobile Whole-room UVGI Device

    Vincent, Richard L / Rudnick, Stephen N / McDevitt, James J / Wallach, Frances R

    Photochemistry and photobiology

    2021  Volume 97, Issue 3, Page(s) 552–559

    Abstract: Mobile whole-room UVGI devices are used in healthcare settings to control surface-borne pathogens. Unfortunately, no standard method comparing the efficacy of these devices is available. We accessed the effect of shadows on UVC 254 nm inactivation. The ... ...

    Abstract Mobile whole-room UVGI devices are used in healthcare settings to control surface-borne pathogens. Unfortunately, no standard method comparing the efficacy of these devices is available. We accessed the effect of shadows on UVC 254 nm inactivation. The evaluation of a mobile whole-room UVGI device used spores of Bacillus atrophaeus as a surrogate for Clostridium difficile and Staphylococcus aureus as a surrogate for MSRA. Inactivation after 10 min of exposure varied significantly depending on whether the spores received direct UV exposure (4.3 log reduction), both direct and reflected UV exposure (3.0-4.0 log reduction) or reflected UV exposure alone (<1.0 log reduction). The susceptibility (z-value) for inactivation of B. atrophaeus spores on a glass surface was estimated to be 0.00312 m
    MeSH term(s) Clostridioides difficile ; Decontamination ; Disinfection ; Spores, Bacterial ; Staphylococcus aureus ; Ultraviolet Rays
    Language English
    Publishing date 2021-04-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 123540-0
    ISSN 1751-1097 ; 0031-8655
    ISSN (online) 1751-1097
    ISSN 0031-8655
    DOI 10.1111/php.13416
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