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  1. Article ; Online: The successful use of a subcutaneous catheter in the management of severe subcutaneous emphysema in a dog with laryngeal crush injury and tracheostomy tube placement.

    Poirier, Maude / Walton, Rebecca A L

    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

    2023  Volume 33, Issue 6, Page(s) 710–714

    Abstract: Objective: To describe the placement of a subcutaneous catheter in a dog for the management of severe subcutaneous emphysema secondary to severe laryngeal crushing injury and temporary tracheostomy tube placement.: Case summary: A 6-year-old male ... ...

    Abstract Objective: To describe the placement of a subcutaneous catheter in a dog for the management of severe subcutaneous emphysema secondary to severe laryngeal crushing injury and temporary tracheostomy tube placement.
    Case summary: A 6-year-old male neutered Kelpie suffered a severe laryngeal crushing injury following a dog attack. Case management included the placement of a temporary tracheostomy tube due to severe respiratory compromise and inspiratory dyspnea associated with the crush injury. During hospitalization, the patient developed severe subcutaneous emphysema, pneumomediastinum, and a pneumothorax as a complication of the laryngeal crushing injury and temporary tracheostomy. A subcutaneous catheter was placed to manage the recurrent subcutaneous emphysema while the tracheostomy stoma healed. Five months posttrauma, the dog returned to normal with mild stridor during excitement and while panting.
    New or unique information provided: This is the first report in veterinary medicine describing the use of a subcutaneous catheter for the management of subcutaneous emphysema secondary to laryngeal crush injury and temporary tracheostomy tube placement.
    MeSH term(s) Humans ; Male ; Dogs ; Animals ; Tracheostomy/veterinary ; Subcutaneous Emphysema/etiology ; Subcutaneous Emphysema/therapy ; Subcutaneous Emphysema/veterinary ; Dyspnea/veterinary ; Crush Injuries/complications ; Crush Injuries/veterinary ; Mediastinal Emphysema/etiology ; Mediastinal Emphysema/veterinary ; Catheters/adverse effects ; Dog Diseases/etiology ; Dog Diseases/surgery
    Language English
    Publishing date 2023-10-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2077212-9
    ISSN 1476-4431 ; 1479-3261
    ISSN (online) 1476-4431
    ISSN 1479-3261
    DOI 10.1111/vec.13322
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  2. Article ; Online: Comparison of venous hemoglobin saturation measurements obtained by in vivo oximetry and calculated from blood gas analysis in critically ill dogs.

    Walton, Rebecca A L / Hansen, Bernie

    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

    2021  Volume 31, Issue 5, Page(s) 578–584

    Abstract: Objective: To compare in vivo central venous hemoglobin saturation measurement (ScvO: Design: Prospective observational study.: Setting: University veterinary teaching hospital intensive care unit.: Animals: A convenience sample of 20 dogs with ...

    Abstract Objective: To compare in vivo central venous hemoglobin saturation measurement (ScvO
    Design: Prospective observational study.
    Setting: University veterinary teaching hospital intensive care unit.
    Animals: A convenience sample of 20 dogs with severe illness.
    Interventions: Dogs were instrumented with either a central venous catheter with an integrated fiber optic cable or a conventional catheter with a fiber optic probe inserted through its distal port. Baseline saturation was measured with the fiber optic system (FSO
    Measurements and main results: Ninety-seven paired measurements from 20 dogs were analyzed. FSO
    Conclusions: Concordance between FSO
    MeSH term(s) Animals ; Blood Gas Analysis/veterinary ; Critical Illness ; Dog Diseases ; Dogs ; Hemoglobins ; Hospitals, Animal ; Hospitals, Teaching ; Oximetry/veterinary ; Oxygen
    Chemical Substances Hemoglobins ; Oxygen (S88TT14065)
    Language English
    Publishing date 2021-07-16
    Publishing country United States
    Document type Journal Article ; Observational Study, Veterinary
    ZDB-ID 2077212-9
    ISSN 1476-4431 ; 1479-3261
    ISSN (online) 1476-4431
    ISSN 1479-3261
    DOI 10.1111/vec.13095
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  3. Article ; Online: Suspected benzodiazepine withdrawal‐associated seizures in 3 young dogs undergoing mechanical ventilation

    Walton, Rebecca A. L. / Enders, Brittany D.

    Journal of Veterinary Emergency and Critical Care. 2022 Nov., v. 32, no. 6 p.800-804

    2022  

    Abstract: OBJECTIVE: To describe new onset of generalized seizures in 3 young dogs following cessation of a benzodiazepine‐containing sedation protocol to facilitate mechanical ventilation (MV) for hypoxemia. SERIES SUMMARY: Three dogs under 5 months of age ... ...

    Abstract OBJECTIVE: To describe new onset of generalized seizures in 3 young dogs following cessation of a benzodiazepine‐containing sedation protocol to facilitate mechanical ventilation (MV) for hypoxemia. SERIES SUMMARY: Three dogs under 5 months of age underwent MV due to severe hypoxemia. All 3 dogs were sedated with a constant rate infusion of benzodiazepines as part of their sedation protocol to facilitate MV. All 3 dogs had an acute onset of generalized seizures within 36 hours of sedation cessation and weaning from MV. All 3 dogs’ seizures were successfully managed with a slow, tapering course of benzodiazepines. One dog was additionally treated with levetiracetam at the time of initial seizure activity, which was discontinued 1 year following discharge and absence of ongoing seizure activity. All 3 dogs were discharged successfully with no reports of ongoing seizures or neurologic deficits after discharge. NEW OR UNIQUE INFORMATION PROVIDED: Young dogs managed with benzodiazepines to facilitate MV may have acute onset of generalized seizures following cessation, which can be successfully managed with short‐term benzodiazepine therapy. The 3 cases in this series demonstrated a positive outcome and were successfully managed following acute onset of generalized seizure activity post‐MV.
    Keywords benzodiazepines ; dogs ; hypoxia ; sedation
    Language English
    Dates of publication 2022-11
    Size p. 800-804.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2077212-9
    ISSN 1476-4431 ; 1479-3261
    ISSN (online) 1476-4431
    ISSN 1479-3261
    DOI 10.1111/vec.13221
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  4. Article ; Online: Suspected benzodiazepine withdrawal-associated seizures in 3 young dogs undergoing mechanical ventilation.

    Walton, Rebecca A L / Enders, Brittany D

    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

    2022  Volume 32, Issue 6, Page(s) 800–804

    Abstract: Objective: To describe new onset of generalized seizures in 3 young dogs following cessation of a benzodiazepine-containing sedation protocol to facilitate mechanical ventilation (MV) for hypoxemia.: Series summary: Three dogs under 5 months of age ... ...

    Abstract Objective: To describe new onset of generalized seizures in 3 young dogs following cessation of a benzodiazepine-containing sedation protocol to facilitate mechanical ventilation (MV) for hypoxemia.
    Series summary: Three dogs under 5 months of age underwent MV due to severe hypoxemia. All 3 dogs were sedated with a constant rate infusion of benzodiazepines as part of their sedation protocol to facilitate MV. All 3 dogs had an acute onset of generalized seizures within 36 hours of sedation cessation and weaning from MV. All 3 dogs' seizures were successfully managed with a slow, tapering course of benzodiazepines. One dog was additionally treated with levetiracetam at the time of initial seizure activity, which was discontinued 1 year following discharge and absence of ongoing seizure activity. All 3 dogs were discharged successfully with no reports of ongoing seizures or neurologic deficits after discharge.
    New or unique information provided: Young dogs managed with benzodiazepines to facilitate MV may have acute onset of generalized seizures following cessation, which can be successfully managed with short-term benzodiazepine therapy. The 3 cases in this series demonstrated a positive outcome and were successfully managed following acute onset of generalized seizure activity post-MV.
    MeSH term(s) Dogs ; Animals ; Benzodiazepines/adverse effects ; Anticonvulsants/adverse effects ; Respiration, Artificial/veterinary ; Seizures/chemically induced ; Seizures/veterinary ; Hypoxia/veterinary ; Dog Diseases/chemically induced ; Dog Diseases/therapy
    Chemical Substances Benzodiazepines (12794-10-4) ; Anticonvulsants
    Language English
    Publishing date 2022-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2077212-9
    ISSN 1476-4431 ; 1479-3261
    ISSN (online) 1476-4431
    ISSN 1479-3261
    DOI 10.1111/vec.13221
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  5. Article ; Online: Successful management of severe carprofen toxicity with manual therapeutic plasma exchange in a dog.

    Buseman, Miranda / Blong, April E / Walton, Rebecca A L

    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

    2022  Volume 32, Issue 5, Page(s) 675–679

    Abstract: Objective: To report the use of manual therapeutic plasma exchange (TPE) in a dog with severe carprofen toxicity.: Summary: A 12-year-old neutered female Pembroke Welsh Corgi weighing 20 kg was evaluated after ingesting 223 mg/kg of carprofen. Emesis ...

    Abstract Objective: To report the use of manual therapeutic plasma exchange (TPE) in a dog with severe carprofen toxicity.
    Summary: A 12-year-old neutered female Pembroke Welsh Corgi weighing 20 kg was evaluated after ingesting 223 mg/kg of carprofen. Emesis was attempted with apomorphine at the primary care veterinarian but was unsuccessful, and a dose of activated charcoal with sorbitol was administered. On presentation to the referral center, approximately 8 hours after ingestion, the dog's physical examination revealed mild abdominal discomfort but was otherwise unremarkable. Treatment consisted of a combination of supportive care including activated charcoal with sorbitol, cholestyramine, IV lipid emulsion, and manual TPE. Blood samples were collected prior to the initiation of manual TPE and at the completion of 12 exchange cycles. Carprofen levels were determined by high-pressure liquid chromatography. A 57% decrease in carprofen levels was achieved with the combination of activated charcoal, cholestyramine, IV lipid emulsion, and manual TPE. The dog did not develop organ dysfunction secondary to toxicity and was discharged 4 days after ingestion.
    New or unique information provided: This report describes the successful decrease of plasma carprofen in a dog with the combination of decontamination techniques and manual TPE. While TPE has been previously reported as a successful therapeutic in dogs with nonsteroidal anti-inflammatory toxicity, including carprofen, equipment and expertise of this platform is not readily available. Manual TPE is technically simple and can be performed in any hospital with a large blood centrifuge.
    MeSH term(s) Animals ; Anti-Inflammatory Agents, Non-Steroidal/toxicity ; Apomorphine ; Carbazoles/toxicity ; Charcoal/therapeutic use ; Cholestyramine Resin ; Dog Diseases/chemically induced ; Dog Diseases/therapy ; Dogs ; Emulsions ; Female ; Lipids ; Plasma Exchange/veterinary ; Sorbitol
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Carbazoles ; Emulsions ; Lipids ; Cholestyramine Resin (11041-12-6) ; Charcoal (16291-96-6) ; Sorbitol (506T60A25R) ; carprofen (FFL0D546HO) ; Apomorphine (N21FAR7B4S)
    Language English
    Publishing date 2022-05-08
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2077212-9
    ISSN 1476-4431 ; 1479-3261
    ISSN (online) 1476-4431
    ISSN 1479-3261
    DOI 10.1111/vec.13203
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  6. Article ; Online: Successful management and recovery of a dog with immune-mediated thrombocytopenia following vincristine overdose.

    Poirier, Maude / Blong, April E / Walton, Rebecca A L

    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

    2022  Volume 32, Issue 4, Page(s) 539–544

    Abstract: Objective: To describe the management and outcome of a dog following a 10-fold dosing error of vincristine.: Case summary: A 2-year-old neutered female Toy Fox Terrier presenting for immune-mediated thrombocytopenia was administered an accidental ... ...

    Abstract Objective: To describe the management and outcome of a dog following a 10-fold dosing error of vincristine.
    Case summary: A 2-year-old neutered female Toy Fox Terrier presenting for immune-mediated thrombocytopenia was administered an accidental overdose of vincristine (0.2 mg/kg [2.71 mg/m
    New or unique information provided: This is the first report of the successful management of severe vincristine overdose in a dog. Therapy included the use of Tbo-filgrastim, folinic acid, and glutamic acid along with aggressive supportive care.
    MeSH term(s) Animals ; Dog Diseases/chemically induced ; Dog Diseases/drug therapy ; Dogs ; Drug Overdose/drug therapy ; Drug Overdose/veterinary ; Drug-Related Side Effects and Adverse Reactions/drug therapy ; Drug-Related Side Effects and Adverse Reactions/veterinary ; Female ; Filgrastim/therapeutic use ; Glutamic Acid ; Leucovorin ; Thrombocytopenia/chemically induced ; Thrombocytopenia/drug therapy ; Thrombocytopenia/veterinary ; Vincristine/therapeutic use
    Chemical Substances Glutamic Acid (3KX376GY7L) ; Vincristine (5J49Q6B70F) ; Filgrastim (PVI5M0M1GW) ; Leucovorin (Q573I9DVLP)
    Language English
    Publishing date 2022-02-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2077212-9
    ISSN 1476-4431 ; 1479-3261
    ISSN (online) 1476-4431
    ISSN 1479-3261
    DOI 10.1111/vec.13187
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  7. Article ; Online: Diagnosis and successful management of an extradural compressive hematoma secondary to diphacinone poisoning in a dog

    Solari, Francesca P. / Sherman, Alec H. / Blong, April E. / Cameron, Starr / Walton, Rebecca A.

    Journal of Veterinary Emergency and Critical Care. 2023 Jan., v. 33, no. 1 p.101-106

    2023  

    Abstract: OBJECTIVE: To describe the successful case management of an extradural hematoma secondary to anticoagulant rodenticide toxicity causing spinal compression and paraplegia. CASE SUMMARY: A 3‐month‐old, female intact, mixed breed dog was presented for a 12‐ ... ...

    Abstract OBJECTIVE: To describe the successful case management of an extradural hematoma secondary to anticoagulant rodenticide toxicity causing spinal compression and paraplegia. CASE SUMMARY: A 3‐month‐old, female intact, mixed breed dog was presented for a 12‐hour history of paraplegia. CBC and biochemistry results were unremarkable, and a coagulation panel revealed prolonged prothrombin time with normal activated partial thromboplastin time. Magnetic resonance imaging revealed an extradural compressive lesion within the vertebral canal extending from T6 to T11, most consistent with an extradural hematoma. Further coagulation testing revealed a coagulopathy caused by vitamin K1 deficiency and confirmed exposure to the anticoagulant rodenticide, diphacinone. The dog was medically managed with fresh frozen plasma, aminocaproic acid, and oral vitamin K1 therapy. A right‐sided T6 to T11 hemilaminectomy was later performed for removal of the extradural hematoma and spinal decompression. The dog's neurological status gradually improved postoperatively and, at the time of discharge, was nonambulatory paraparetic with voluntary micturition. Four weeks postoperatively, the dog had normal prothrombin and activated partial thromboplastin times and was nonambulatory paraparetic with strong motor function. NEW OR UNIQUE INFORMATION PROVIDED: This is the first reported case of a dog with an extradural hematoma secondary to anticoagulant rodenticide causing spinal cord compression and neurological deficits. Surgical management of this case was successful and resulted in improvement of neurological signs. Extradural hematoma should be considered as a potential location of bleeding in rodenticide toxicity as well as a differential diagnosis in patients with neurological deficits.
    Keywords coagulation ; diphacinone ; dogs ; females ; hematoma ; magnetism ; phylloquinone ; prothrombin ; spinal cord ; surgery ; thromboplastin ; toxicity
    Language English
    Dates of publication 2023-01
    Size p. 101-106.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note Case Reports
    ZDB-ID 2077212-9
    ISSN 1476-4431 ; 1479-3261
    ISSN (online) 1476-4431
    ISSN 1479-3261
    DOI 10.1111/vec.13248
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  8. Article: Comparison of venous hemoglobin saturation measurements obtained by in vivo oximetry and calculated from blood gas analysis in critically ill dogs

    Walton, Rebecca A. L. / Hansen, Bernie

    Journal of veterinary emergency and critical care. 2021 Sept., v. 31, no. 5

    2021  

    Abstract: OBJECTIVE: To compare in vivo central venous hemoglobin saturation measurement (ScvO₂) using a fiber optic catheter with saturation calculated from blood gas analysis in critically ill dogs. DESIGN: Prospective observational study. SETTING: University ... ...

    Abstract OBJECTIVE: To compare in vivo central venous hemoglobin saturation measurement (ScvO₂) using a fiber optic catheter with saturation calculated from blood gas analysis in critically ill dogs. DESIGN: Prospective observational study. SETTING: University veterinary teaching hospital intensive care unit. ANIMALS: A convenience sample of 20 dogs with severe illness. INTERVENTIONS: Dogs were instrumented with either a central venous catheter with an integrated fiber optic cable or a conventional catheter with a fiber optic probe inserted through its distal port. Baseline saturation was measured with the fiber optic system (FSO₂), then monitored continuously. Central venous blood was collected for analysis and FSO₂ was recorded by the principal investigator (PI) or nursing staff participating in data collection (staff) at baseline and at 1, 2, 3, and 6 hours. Hemoglobin oxygen saturation (SO₂) values calculated using human Bohr coefficients were taken directly from the analyzer (GPSO₂), and were also calculated using temperature‐correction and canine Bohr coefficients (RSO₂). MEASUREMENTS AND MAIN RESULTS: Ninety‐seven paired measurements from 20 dogs were analyzed. FSO₂ obtained by the PI (n = 41) had better agreement with both GPSO₂ (concordance correlation coefficient ρc = 0.926 vs 0.5562) and RSO₂ (ρc = 0.75 for PI vs 0.54) than did staff (n = 56). RSO₂ values were always smaller than GPSO₂. FSO2 ‐ GPSO₂ differences were smaller when measurements were collected by the PI versus Staff (mean difference 0.21 vs −6.6, respectively, P < 0.02). Thirty‐six of 41 FSO₂ values obtained by PI were within 5% of GPSO₂. CONCLUSIONS: Concordance between FSO₂ and either calculation method was low, but was better when performed by PI. The larger difference between methods when using RSO₂ suggests a positive bias by FSO₂. Difficulty obtaining stable measurements may have contributed to the poor concordance between methods within Staff.
    Keywords blood ; blood gases ; central venous catheters ; data collection ; disease severity ; dogs ; fiber optics ; hemoglobin ; hospitals ; humans ; observational studies ; oxygen
    Language English
    Dates of publication 2021-09
    Size p. 578-584.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2077212-9
    ISSN 1476-4431 ; 1479-3261
    ISSN (online) 1476-4431
    ISSN 1479-3261
    DOI 10.1111/vec.13095
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  9. Article ; Online: Pathology in Practice.

    Lemburg, Brigid K / Smith, Jodi D / Blong, April E / Walton, Rebecca A

    Journal of the American Veterinary Medical Association

    2022  Volume 259, Issue S2, Page(s) 1–3

    Abstract: In collaboration with the American College of Veterinary Pathologists. ...

    Abstract In collaboration with the American College of Veterinary Pathologists.
    MeSH term(s) Animals ; Humans ; Pathology, Veterinary ; United States ; Veterinarians
    Language English
    Publishing date 2022-05-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.20.11.0638
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  10. Article ; Online: Feline cardiopulmonary resuscitation: Getting the most out of all nine lives.

    Ward, Melody J / Blong, April E / Walton, Rebecca A

    Journal of feline medicine and surgery

    2021  Volume 23, Issue 5, Page(s) 447–461

    Abstract: Practical relevance: Cardiopulmonary arrest (CPA) can occur in any veterinary or animal care setting and is a particular risk in scenarios involving ill, injured or anesthetized patients. Education of all staff on the prevention and recognition of CPA, ... ...

    Abstract Practical relevance: Cardiopulmonary arrest (CPA) can occur in any veterinary or animal care setting and is a particular risk in scenarios involving ill, injured or anesthetized patients. Education of all staff on the prevention and recognition of CPA, as well as the performance of cardiopulmonary resuscitation (CPR), is vital to influencing outcome.
    Evidence base: While there is a plethora of information regarding CPA and CPR in human medicine, there are comparably few studies in the veterinary literature. Many of the current veterinary guidelines are extrapolated from human medicine or studies based on animal models. Ongoing work is needed to tailor guidelines and recommendations to our domestic feline (and canine) patients in a clinical setting.
    Aim: The aim of this article, which is intended for veterinarians in all areas of small animal practice, is to provide an evidence-based review of CPA and CPR in feline patients. The authors have drawn heavily on detailed recommendations published by the Reassessment Campaign on Veterinary Resuscitation (RECOVER) initiative - one of the few resources specific to the veterinary clinical setting - as well as reviewing the available peer-reviewed literature studies, in constructing this article. Among the topics discussed are recognizing and preventing CPA, staff training and clinic preparedness, basic life support and advanced life support interventions, and appropriate post-cardiac arrest care.
    MeSH term(s) Animal Husbandry ; Animals ; Cardiopulmonary Resuscitation/veterinary ; Cat Diseases/therapy ; Cats ; Dog Diseases ; Dogs ; Heart Arrest/therapy ; Heart Arrest/veterinary ; Humans ; Veterinarians
    Language English
    Publishing date 2021-03-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2049047-1
    ISSN 1532-2750 ; 1098-612X
    ISSN (online) 1532-2750
    ISSN 1098-612X
    DOI 10.1177/1098612X211004811
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