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  1. AU="Wan, Xuan"
  2. AU="Camille Fritzell"
  3. AU=Wei Huijun
  4. AU="Levine, Morgan E"
  5. AU="Chen, Yalei"
  6. AU="Rogaeva, Ekaterina" AU="Rogaeva, Ekaterina"
  7. AU="Jain, Ishaan"
  8. AU="Chatelier, Josh"
  9. AU="Passarelli, L."
  10. AU="Marques, R"
  11. AU="Restaino, Valeria"
  12. AU="Wang, Haochen"
  13. AU=Shoib Sheikh
  14. AU=Patel Ishan
  15. AU="Mongioì, Laura M"
  16. AU="Fernández-Pacheco, Borja Camacho"
  17. AU=Waghmare Alpana AU=Waghmare Alpana
  18. AU="Peyre, Marion"
  19. AU=Mulazimoglu L
  20. AU=Roy Satyaki
  21. AU="Li Yuanyuan"
  22. AU=Khan Shehryar
  23. AU=Cole Sarah L
  24. AU="Júnior, Raimundo Nonato Colares Camargo"
  25. AU="Feeney, Judith A"

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  1. Artikel ; Online: Epithelial IL5RA promotes epithelial-mesenchymal transition in pulmonary fibrosis via Jak2/STAT3 cascade.

    Chen, Shuyun / Zhao, Tiantian / Xie, Shiguang / Wan, Xuan

    Pulmonary pharmacology & therapeutics

    2024  Band 84, Seite(n) 102286

    Abstract: Pulmonary fibrosis is a progressive and debilitating lung disease characterized by the excessive accumulation of extracellular matrix (ECM) components within the lung parenchyma. However, the underlying mechanism remains largely elusive, and the ... ...

    Abstract Pulmonary fibrosis is a progressive and debilitating lung disease characterized by the excessive accumulation of extracellular matrix (ECM) components within the lung parenchyma. However, the underlying mechanism remains largely elusive, and the treatment options available for pulmonary fibrosis are limited. Interleukin 5 receptor, alpha (IL5RA) is a well-established regulator of eosinophil activation, involved in eosinophil-mediated anti-parasitic activities and allergic reactions. Recent studies have indicated additional roles of IL5RA in lung epithelium and fibroblasts. Nevertheless, its involvement in pulmonary fibrosis remains unclear. In present study, we employed single-cell analyses alongside molecular and cellular assays to unveil the expression of IL5RA in lung epithelial cells. Moreover, using both in vitro and in vivo models, we demonstrated a notable upregulation of epithelial IL5RA during the progression of pulmonary fibrosis. This upregulated IL5RA expression subsequently promotes epithelial-mesenchymal transition (EMT), leading to the generation of mesenchymal phenotype with augmented capability for ECM production. Importantly, our findings uncovered that the pro-fibrotic function of IL5RA is mediated by Jak2/STAT3 signaling cascades. Inhibiting IL5RA has the potential to deactivate Jak2/STAT3 and suppress the downstream EMT process and ECM production, thereby offering a promising therapeutic strategy for pulmonary fibrosis.
    Mesh-Begriff(e) Humans ; Epithelial-Mesenchymal Transition/physiology ; Fibrosis ; Interleukin-5 Receptor alpha Subunit/metabolism ; Lung/metabolism ; Pulmonary Fibrosis/metabolism ; Receptors, Interleukin-5/metabolism ; STAT3 Transcription Factor/metabolism
    Chemische Substanzen IL5RA protein, human ; Interleukin-5 Receptor alpha Subunit ; Receptors, Interleukin-5 ; STAT3 protein, human ; STAT3 Transcription Factor ; JAK2 protein, human (EC 2.7.10.2)
    Sprache Englisch
    Erscheinungsdatum 2024-01-06
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1399707-5
    ISSN 1522-9629 ; 1094-5539
    ISSN (online) 1522-9629
    ISSN 1094-5539
    DOI 10.1016/j.pupt.2024.102286
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  2. Artikel ; Online: Paramyosin from field snail (Bellamya quadrata): Structural characteristics and its contribution to enhanced the gel properties of myofibrillar protein.

    Wan, Xuan-Ying / Pan, Yu-Ping / Shu, Mei / Geng, Jie-Ting / Wu, Guo-Ping / Zhong, Chan

    International journal of biological macromolecules

    2024  Band 262, Heft Pt 2, Seite(n) 130097

    Abstract: To assess the blending effect of field snails with grass carp muscle, the effects of paramyosin (PM) and actomyosin (AM) with different mixture ratios on the gel properties of the binary blend system were investigated in our work. The purified PM from ... ...

    Abstract To assess the blending effect of field snails with grass carp muscle, the effects of paramyosin (PM) and actomyosin (AM) with different mixture ratios on the gel properties of the binary blend system were investigated in our work. The purified PM from field snail muscle was about 95 kDa on SDS-PAGE. Its main secondary structure was α-helix, which reached to 97.97 %. When the amount of PM increased in the binary blend system, their rheological indices and gel strength were improved. The water holding capacity (WHC) increased to 86.30 % at a mixture ratio of 2:8. However, the WHC and the area of immobile water (P
    Mesh-Begriff(e) Animals ; Tropomyosin ; Gels/chemistry ; Actomyosin/chemistry ; Snails ; Water/chemistry
    Chemische Substanzen Tropomyosin ; Gels ; Actomyosin (9013-26-7) ; Water (059QF0KO0R)
    Sprache Englisch
    Erscheinungsdatum 2024-02-09
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.130097
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  3. Artikel: GW4869 Can Inhibit Epithelial-Mesenchymal Transition and Extracellular HSP90α in Gefitinib-Sensitive NSCLC Cells.

    Wan, Xuan / Fang, Yuting / Du, Jiangzhou / Cai, Shaoxi / Dong, Hangming

    OncoTargets and therapy

    2023  Band 16, Seite(n) 913–922

    Abstract: Objective: GW4869 is an exosomal inhibitor. It is necessary to delay the occurrence of gefitinib resistance during non-small-cell lung cancer (NSCLC) treatment. This study aimed to investigate the anti-tumor effects of GW4869 on epithelial-mesenchymal ... ...

    Abstract Objective: GW4869 is an exosomal inhibitor. It is necessary to delay the occurrence of gefitinib resistance during non-small-cell lung cancer (NSCLC) treatment. This study aimed to investigate the anti-tumor effects of GW4869 on epithelial-mesenchymal transition (EMT) and expression of extracellular heat shock protein 90α (eHSP90α) that contributes to acquired resisitance. Our study provides a new sight into the treatment of EGFR-mutated NSCLC.
    Materials and methods: We performed western blotting to detect levels of EMT and eHSP90α. Wound healing and transwell assays were performed to evaluate the behavioral dynamics of EMT. A nude mouse model of HCC827 was established in vivo.
    Results: GW4869 inhibited the expression of eHSP90α, EMT, invasion and migration abilities of HCC827 and PC9. GW4869 enhanced sensitivity to gefitinib in BALB/c nude mice bearing tumors of HCC827.
    Conclusion: These studies suggest that GW4869 can inhibit EMT and extracellular HSP90α, providing new strategies for enhancing gefitinib sensitivity in NSCLC.
    Sprache Englisch
    Erscheinungsdatum 2023-11-08
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article
    ZDB-ID 2495130-4
    ISSN 1178-6930
    ISSN 1178-6930
    DOI 10.2147/OTT.S428707
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  4. Artikel ; Online: Effects of a Shift of the Signal Peptide Cleavage Site in Signal Peptide Variant on the Synthesis and Secretion of SARS-CoV-2 Spike Protein.

    Zhang, Zhikai / Wan, Xuan / Li, Xinyue / Wan, Chengsong

    Molecules (Basel, Switzerland)

    2022  Band 27, Heft 19

    Abstract: The COVID-19 pandemic is caused by SARS-CoV-2; the spike protein is a key structural protein that mediates infection of the host by SARS-CoV-2. In this study, we aimed to evaluate the effects of signal peptide on the secretion and release of SARS-CoV-2 ... ...

    Abstract The COVID-19 pandemic is caused by SARS-CoV-2; the spike protein is a key structural protein that mediates infection of the host by SARS-CoV-2. In this study, we aimed to evaluate the effects of signal peptide on the secretion and release of SARS-CoV-2 spike protein. Therefore, we constructed a signal peptide deletion mutant and three signal peptide site-directed mutants. The (H) region and (C) region in the signal peptide of L5F-S13I mutant have changed significantly, compared with wild type, L5F and S13I. We demonstrated the effects of signal peptide on the secretion and synthesis of RBD protein, finding that mutation of S13 to I13 on the signal peptide is more conducive to the secretion of RBD protein, which was mainly due to the shift of the signal peptide cleavage site in the mutant S13I. Here, we not only investigated the structure of the N-terminal signal peptide of the SARS-CoV-2 spike protein but also considered possible secretory pathways. We suggest that the development of drugs that target the signal peptide of the SARS-CoV-2 spike protein may have potential to treat COVID-19 in the future.
    Mesh-Begriff(e) COVID-19 ; Humans ; Pandemics ; Protein Sorting Signals/genetics ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/metabolism
    Chemische Substanzen Protein Sorting Signals ; Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2022-10-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27196688
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Hefte anzeigen

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  5. Artikel ; Online: AI-aided geometric design of anti-infection catheters.

    Zhou, Tingtao / Wan, Xuan / Huang, Daniel Zhengyu / Li, Zongyi / Peng, Zhiwei / Anandkumar, Anima / Brady, John F / Sternberg, Paul W / Daraio, Chiara

    Science advances

    2024  Band 10, Heft 1, Seite(n) eadj1741

    Abstract: Bacteria can swim upstream in a narrow tube and pose a clinical threat of urinary tract infection to patients implanted with catheters. Coatings and structured surfaces have been proposed to repel bacteria, but no such approach thoroughly addresses the ... ...

    Abstract Bacteria can swim upstream in a narrow tube and pose a clinical threat of urinary tract infection to patients implanted with catheters. Coatings and structured surfaces have been proposed to repel bacteria, but no such approach thoroughly addresses the contamination problem in catheters. Here, on the basis of the physical mechanism of upstream swimming, we propose a novel geometric design, optimized by an artificial intelligence model. Using
    Mesh-Begriff(e) Humans ; Urinary Catheters/microbiology ; Artificial Intelligence ; Urinary Tract Infections/prevention & control ; Urinary Tract Infections/microbiology ; Bacteria ; Escherichia coli ; Hydrolases
    Chemische Substanzen Hydrolases (EC 3.-)
    Sprache Englisch
    Erscheinungsdatum 2024-01-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adj1741
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Enhancing the Immunogenicity of RBD Protein Variants through Amino Acid E484 Mutation in SARS-CoV-2.

    Zhang, Zhikai / Wan, Xuan / Li, Xinyue / Cai, Shaoxi / Wan, Chengsong

    Viruses

    2022  Band 14, Heft 9

    Abstract: In the context of the COVID-19 pandemic, conducting antibody testing and vaccination is critical. In particular, the continued evolution of SARS-CoV-2 raises concerns about the effectiveness of vaccines currently in use and the activity of neutralizing ... ...

    Abstract In the context of the COVID-19 pandemic, conducting antibody testing and vaccination is critical. In particular, the continued evolution of SARS-CoV-2 raises concerns about the effectiveness of vaccines currently in use and the activity of neutralizing antibodies. Here, we used the
    Mesh-Begriff(e) Amino Acids/genetics ; Animals ; Antibodies, Neutralizing/chemistry ; Antibodies, Viral ; COVID-19/prevention & control ; Escherichia coli/genetics ; Humans ; Mice ; Mutant Proteins/genetics ; Mutation ; Neutralization Tests ; Pandemics ; Recombinant Proteins ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus ; Viral Vaccines
    Chemische Substanzen Amino Acids ; Antibodies, Neutralizing ; Antibodies, Viral ; Mutant Proteins ; Recombinant Proteins ; Spike Glycoprotein, Coronavirus ; Viral Vaccines ; spike protein, SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2022-09-13
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14092020
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Effects of different takeover request interfaces on takeover behavior and performance during conditionally automated driving.

    Ou, Yang-Kun / Huang, Wan-Xuan / Fang, Chen-Wen

    Accident; analysis and prevention

    2021  Band 162, Seite(n) 106425

    Abstract: Automated driving is a developing trend that is coming to the consumer market, and conditionally automated driving (CAD) is anticipated to become the primary automated driving system. For enhancing both the comfort and security of human drivers in self- ... ...

    Abstract Automated driving is a developing trend that is coming to the consumer market, and conditionally automated driving (CAD) is anticipated to become the primary automated driving system. For enhancing both the comfort and security of human drivers in self-driving cars, the most significant concern of CAD is ensuring that not only can the driver conduct non-driving related tasks (NDRT) while automated driving is in progress, but also quickly and competently take over when the system reaches a limit and issues a takeover request (TOR). However, the level of distraction by NDRTs may affect the transition from automated driving to the human driver taking over. The focus of the present study was allowing a driver immersed in NDRTs to discover the TOR and take control of the driving quickly. A 3×2×2 factor experimental design was used: vehicle display interface information load (basic vs. prediction vs. advanced prediction interfaces); TOR information load (directional vs. non-directional information notifications); and degree of NDRT immersion (not performing vs. performing an NDRT when TOR prompt was issued). 48 participants were recruited, and different automotive display interfaces were used as TOR prompts with different information loads during driving to analyze the takeover behavior, performance, and subjective perception of the drivers, who were immersed in a smartphone-related task. The takeover process out of NDRT immersion was found to be more efficient with the advanced prediction interface, compared to the other two interfaces. All groups achieved faster takeovers and demonstrated better takeover performance if given directional rather than non-directional information, regardless of interface type or NDRT immersion.
    Mesh-Begriff(e) Accidents, Traffic ; Automation ; Automobile Driving ; Automobiles ; Humans ; Smartphone
    Sprache Englisch
    Erscheinungsdatum 2021-10-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 210223-7
    ISSN 1879-2057 ; 0001-4575
    ISSN (online) 1879-2057
    ISSN 0001-4575
    DOI 10.1016/j.aap.2021.106425
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  8. Artikel ; Online: p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma.

    Xie, Shiguang / Wan, Xuan / Chen, Shuyun / Hu, Yan / Liu, Xiaoming

    Laboratory investigation; a journal of technical methods and pathology

    2022  Band 102, Heft 10, Seite(n) 1109–1120

    Abstract: Lung squamous cell carcinoma (LSCC) is a prevalent and progressive subtype of lung cancer. This study aimed to substantiate the regulatory effect of the PAK2/SOX2/DEK axis on the LSCC development. LSCC tissues (n = 83) and adjacent normal tissues were ... ...

    Abstract Lung squamous cell carcinoma (LSCC) is a prevalent and progressive subtype of lung cancer. This study aimed to substantiate the regulatory effect of the PAK2/SOX2/DEK axis on the LSCC development. LSCC tissues (n = 83) and adjacent normal tissues were collected and SOX2 expression was determined by qRT-PCR and Western blotting. Correlation between SOX2 expression and the prognosis of LSCC patients was then explored utilizing Kaplan-Meier analysis. Co-immunoprecipitation and glutathione-S-transferase pull-down assays were conducted to validate the binding of SOX2 to DEK. Gain- and loss- of function assays were then performed on LSCC cells, with CCK-8 and Transwell assays applied to detect the malignant behaviors of cells. A mouse xenograft model of LSCC was further established for in vivo validation. The expression levels of SOX2, PAK2 and DEK were up-regulated in LSCC tissues and cells. SOX2 overexpression was correlated with poor prognosis of LSCC patients. Knockdown of SOX2 weakened the viability and the migratory and invasive potential of LSCC cells. Further, PAK2 directly interacted with SOX2. PAK2 overexpression accelerated the malignant phenotypes of LSCC cells through interplay with SOX2. Moreover, SOX2 activated the expression of DEK, and silencing DEK attenuated the malignant behaviors of LSCC cells. In conclusion, PAK2 could bind to the transcription factor SOX2 and thus activate the expression of DEK, thereby driving the malignant phenotypes of LSCC cells both in vivo and in vitro.
    Mesh-Begriff(e) Animals ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Squamous Cell/metabolism ; Cell Line, Tumor ; Cell Proliferation/genetics ; Chromosomal Proteins, Non-Histone/genetics ; Chromosomal Proteins, Non-Histone/metabolism ; Gene Expression Regulation, Neoplastic ; Glutathione/metabolism ; Humans ; Laryngeal Neoplasms/genetics ; Laryngeal Neoplasms/pathology ; Lung/metabolism ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Mice ; MicroRNAs/genetics ; Oncogene Proteins ; Poly-ADP-Ribose Binding Proteins/genetics ; Poly-ADP-Ribose Binding Proteins/metabolism ; SOXB1 Transcription Factors ; Sincalide/genetics ; Sincalide/metabolism ; p21-Activated Kinases/genetics ; p21-Activated Kinases/metabolism
    Chemische Substanzen Chromosomal Proteins, Non-Histone ; DEK protein, human ; MicroRNAs ; Oncogene Proteins ; Poly-ADP-Ribose Binding Proteins ; SOX2 protein, human ; SOXB1 Transcription Factors ; PAK2 protein, human (EC 2.7.11.1) ; p21-Activated Kinases (EC 2.7.11.1) ; Glutathione (GAN16C9B8O) ; Sincalide (M03GIQ7Z6P)
    Sprache Englisch
    Erscheinungsdatum 2022-07-11
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80178-1
    ISSN 1530-0307 ; 0023-6837
    ISSN (online) 1530-0307
    ISSN 0023-6837
    DOI 10.1038/s41374-022-00808-5
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Comparison of Vancomycin Trough-Based and 24-Hour Area Under the Curve Over Minimum Inhibitory Concentration (AUC/MIC)-Based Therapeutic Drug Monitoring in Pediatric Patients.

    Lim, Wan Xuan Selina / Seah, Xue Fen Valerie / Thoon, Koh Cheng / Han, Zhe

    The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

    2023  Band 28, Heft 5, Seite(n) 430–438

    Abstract: Objectives: Vancomycin 24-hour area under the curve over minimum inhibitory concentration (AUC/MIC) monitoring has been recommended over trough-based monitoring in pediatric patients. This study compared the proportion of target attainment between ... ...

    Abstract Objectives: Vancomycin 24-hour area under the curve over minimum inhibitory concentration (AUC/MIC) monitoring has been recommended over trough-based monitoring in pediatric patients. This study compared the proportion of target attainment between vancomycin AUC/MIC and trough-based methods, and identified risk factors for subtherapeutic initial extrapolated targets.
    Methods: This was a retrospective, observational study conducted at KK Women's and Children's Hospital (KKH), Singapore. Patients aged 1 month to 18 years with stable renal function who received intravenous vancomycin between January 2014 and October 2017, with at least 2 vancomycin serum concentrations obtained after the first dose of vancomycin, were included. Using a pharmacokinetic software, namely Adult and Pediatric Kinetics (APK), initial extrapolated steady-state troughs and 24-hour AUC were determined by using a one-compartmental model. Statistical tests included Wilcoxon rank sum test, McNemar test, logistic regression, and classification and regression tree (CART) analysis.
    Results: Of the 82 pediatric patients included, a significantly larger proportion of patients achieved therapeutic targets when the AUC/MIC-based method (24, 29.3%) was used than with the trough-based method (9, 11.0%; p < 0.01). Patients with estimated glomerular filtration rate (eGFR) ≥60 mL/min/1.73 m
    Conclusion: The AUC/MIC-based vancomycin monitoring may be preferred because a larger proportion of patients could achieve initial therapeutic targets. Future prospective studies with larger sample size will be required to determine the optimal vancomycin strategy for pediatric patients.
    Sprache Englisch
    Erscheinungsdatum 2023-10-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 3028543-4
    ISSN 1551-6776
    ISSN 1551-6776
    DOI 10.5863/1551-6776-28.5.430
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: The Relationships between Waxes and Storage Quality Indexes of Fruits of Three Plum Cultivars

    Zhu, Shouliang / Huang, Shian / Lin, Xin / Wan, Xuan / Zhang, Qin / Peng, Junsen / Luo, Dengcan / Zhang, Yun / Dong, Xiaoqing

    Foods. 2023 Apr. 20, v. 12, no. 8

    2023  

    Abstract: In the present study, the cuticular wax morphology, composition and the relationship with storage quality in three plum cultivars of Prunus salicina ‘Kongxin’ (KXL), Prunus salicina ‘Fengtang’ (FTL) and Prunus salicina ‘Cuihong’ (CHL) were investigated ... ...

    Abstract In the present study, the cuticular wax morphology, composition and the relationship with storage quality in three plum cultivars of Prunus salicina ‘Kongxin’ (KXL), Prunus salicina ‘Fengtang’ (FTL) and Prunus salicina ‘Cuihong’ (CHL) were investigated during storage at room temperature of 25 ± 1 °C. The results illustrated that the highest cuticular wax concentration was discovered in KXL, followed by FTL and the lowest in CHL. The fruit wax composition of the three plum cultivars was similar and principally composed of alkanes, alcohols, fatty acids, ketones, aldehydes, esters, triterpenes and olefins. Alcohols, alkanes and triterpenes were the dominant fruit wax compounds of the three plum cultivars. After storage for 20 d at room temperature, the variation of cuticular wax crystal structure and composition showed significant cultivar-associated differences. The total wax content decreased for FTL and CHL and increased for KXL, and the wax crystal degraded and melted together over time. The higher contents of the main components in the three plum cultivars were nonacosane, 1-triacontanol, 1-heneicosanol, nonacosan-10-one, octacosanal, ursolic aldehyde and oleic acid. Alcohols, triterpenes, fatty acids and aldehydes were most dramatically correlated with the softening of fruit and storage quality, and alkanes, esters and olefins were most significantly correlated with the water loss. Nonacosane and ursolic aldehyde can enhance the water retention of fruit. Overall, this study will provide a theoretical reference for the further precise development of edible plum fruit wax.
    Schlagwörter Prunus salicina ; aldehydes ; ambient temperature ; crystal structure ; cultivars ; epicuticular wax ; fruits ; oleic acid ; plums ; storage quality ; triterpenoids
    Sprache Englisch
    Erscheinungsverlauf 2023-0420
    Erscheinungsort Multidisciplinary Digital Publishing Institute
    Dokumenttyp Artikel ; Online
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12081717
    Datenquelle NAL Katalog (AGRICOLA)

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