LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 22

Search options

  1. Article ; Online: A novel particle swarm optimization based on hybrid-learning model.

    Wang, Yufeng / Wang, BoCheng / Li, Zhuang / Xu, Chunyu

    Mathematical biosciences and engineering : MBE

    2023  Volume 20, Issue 4, Page(s) 7056–7087

    Abstract: The convergence speed and the diversity of the population plays a critical role in the performance of particle swarm optimization (PSO). In order to balance the trade-off between exploration and exploitation, a novel particle swarm optimization based on ... ...

    Abstract The convergence speed and the diversity of the population plays a critical role in the performance of particle swarm optimization (PSO). In order to balance the trade-off between exploration and exploitation, a novel particle swarm optimization based on the hybrid learning model (PSO-HLM) is proposed. In the early iteration stage, PSO-HLM updates the velocity of the particle based on the hybrid learning model, which can improve the convergence speed. At the end of the iteration, PSO-HLM employs a multi-pools fusion strategy to mutate the newly generated particles, which can expand the population diversity, thus avoid PSO-HLM falling into a local optima. In order to understand the strengths and weaknesses of PSO-HLM, several experiments are carried out on 30 benchmark functions. Experimental results show that the performance of PSO-HLM is better than other the-state-of-the-art algorithms.
    Language English
    Publishing date 2023-05-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2265126-3
    ISSN 1551-0018 ; 1551-0018
    ISSN (online) 1551-0018
    ISSN 1551-0018
    DOI 10.3934/mbe.2023305
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Prognostic Value of Different Computed Tomography Scoring Systems in Patients With Severe Traumatic Brain Injury Undergoing Decompressive Craniectomy.

    Zhao, Zhi-Jie / Chen, Di / Zhou, Lai-Yang / Sun, Zhao-Liang / Wang, Bo-Cheng / Feng, Dong-Fu

    Journal of computer assisted tomography

    2022  Volume 46, Issue 5, Page(s) 800–807

    Abstract: Objective: In this study, we investigate the preoperative and postoperative computed tomography (CT) scores in severe traumatic brain injury (TBI) patients undergoing decompressive craniectomy (DC) and compare their predictive accuracy.: Methods: ... ...

    Abstract Objective: In this study, we investigate the preoperative and postoperative computed tomography (CT) scores in severe traumatic brain injury (TBI) patients undergoing decompressive craniectomy (DC) and compare their predictive accuracy.
    Methods: Univariate and multivariate logistic regression analyses were used to determine the relationship between CT score (preoperative and postoperative) and mortality at 30 days after injury. The discriminatory power of preoperative and postoperative CT score was assessed by the area under the receiver operating characteristic curve (AUC).
    Results: Multivariate logistic regression analysis adjusted for the established predictors of TBI outcomes showed that preoperative Rotterdam CT score (odds ratio [OR], 3.60; 95% confidence interval [CI], 1.13-11.50; P = 0.030), postoperative Rotterdam CT score (OR, 4.17; 95% CI, 1.63-10.66; P = 0.003), preoperative Stockholm CT score (OR, 3.41; 95% CI, 1.42-8.18; P = 0.006), postoperative Stockholm CT score (OR, 4.50; 95% CI, 1.60-12.64; P = 0.004), preoperative Helsinki CT score (OR, 1.44; 95% CI, 1.03-2.02; P = 0.031), and postoperative Helsinki CT score (OR, 2.55; 95% CI, 1.32-4.95; P = 0.005) were significantly associated with mortality. The performance of the postoperative Rotterdam CT score was superior to the preoperative Rotterdam CT score (AUC, 0.82-0.97 vs 0.71-0.91). The postoperative Stockholm CT score was superior to the preoperative Stockholm CT score (AUC, 0.76-0.94 vs 0.72-0.92). The postoperative Helsinki CT score was superior to the preoperative Helsinki CT score (AUC, 0.88-0.99 vs 0.65-0.87).
    Conclusions: In conclusion, assessing the CT score before and after DC may be more precise and efficient for predicting early mortality in severe TBI patients who undergo DC.
    MeSH term(s) Brain Injuries, Traumatic/diagnostic imaging ; Brain Injuries, Traumatic/surgery ; Decompressive Craniectomy/methods ; Humans ; Prognosis ; Retrospective Studies ; Tomography, X-Ray Computed/methods ; Treatment Outcome
    Language English
    Publishing date 2022-05-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80392-3
    ISSN 1532-3145 ; 0363-8715
    ISSN (online) 1532-3145
    ISSN 0363-8715
    DOI 10.1097/RCT.0000000000001343
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Protection-Free Strategy for the Synthesis of Boro-Depsipeptides in Aqueous Media under Microwave-Assisted Conditions.

    Qiu, Shuo-Bei / Liu, Pei-Yao / Wang, Bo-Cheng / Chen, Pin-Rui / Xiao, Jing-Han / Hsu, Ting-Yu / Pan, Kuan-Lin / Lai, Zhi-Yin / Chen, Yi-Wei / Chen, Ying-Chuan / Chen, Jen-Kun / Pan, Po-Shen

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 7

    Abstract: In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment. The linker-free DAHMI fluorescent tagging approach was used on selected boron-containing ... ...

    Abstract In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment. The linker-free DAHMI fluorescent tagging approach was used on selected boron-containing compounds to study the relationship between their structures and their level of cellular uptake of HEK293 cells. The biological data retrieved from the DAHMI experiments indicated that while the structures of tested compounds may be highly similar, their bio-distribution profile could be vastly distinctive. The reported optimized one-pot synthetic strategy along the linker-free in vitro testing protocol could provide an efficient platform to accelerate the development of boron-containing drugs.
    MeSH term(s) Boron ; Depsipeptides/chemistry ; HEK293 Cells ; Humans ; Microwaves
    Chemical Substances Depsipeptides ; Boron (N9E3X5056Q)
    Language English
    Publishing date 2022-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27072325
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Carbazole/Benzimidazole-Based Bipolar Molecules as the Hosts for Phosphorescent and Thermally Activated Delayed Fluorescence Emitters for Efficient OLEDs.

    Gao, Zhen-Jie / Yeh, Tzu-Hung / Xu, Jing-Jie / Lee, Chih-Chien / Chowdhury, Anuradha / Wang, Bo-Cheng / Liu, Shun-Wei / Chen, Chih-Hsin

    ACS omega

    2020  Volume 5, Issue 18, Page(s) 10553–10561

    Abstract: A series of carbazole/benzimidazole-based molecules, namely, ...

    Abstract A series of carbazole/benzimidazole-based molecules, namely,
    Language English
    Publishing date 2020-05-03
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.0c00967
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Simultaneous quantification of six indicator compounds in Wen-Qing-Yin by high-performance liquid chromatography-diode array detection

    Yeh, Chi-Chen / Huang, Shih-Shan / Liu, Po-Yu / Wang, Bo-Cheng / Tsai, Chia-Fen / Wang, Der-Yuan / Cheng, Hwei-Fang

    Yàowù shípǐn fēnxī. 2019 July, v. 27, no. 3

    2019  

    Abstract: A simple gradient high-performance liquid chromatography with diode array detection (HPLC-DAD) method was used to simultaneously to analyze characteristics of six indicator compounds in the traditional Chinese medicine (TCM) formulation Wen-Qing-Yin (WQY) ...

    Abstract A simple gradient high-performance liquid chromatography with diode array detection (HPLC-DAD) method was used to simultaneously to analyze characteristics of six indicator compounds in the traditional Chinese medicine (TCM) formulation Wen-Qing-Yin (WQY). Separate optimization was performed using a Cosmosil C18 column gradient method with 0.1% formic acid in both mobile phases of aqueous and acetonitrile (ACN), at a flow rate, detection wavelength, and sample volume of 1.8 mL/min, 268 nm, and 10 μL, respectively. The linear regression of six active compounds berberine (BER), baicalin (BAI), ferulic acid (FER), geniposide (GEN), hydorxymethoxylfurfural (HMF), and paeoniflorin (PAE) was produced at the concentration range of 10–2000 μg/mL. The method validation revealed an acceptable precision (intra- and inter-day precision < 3.39% and 4.11%, respectively) and recovery (85.60–110.45% and 86.58–110.90%), a recovery range of 86.61–109.42%, and sensitivity (limit of detection [LOD] and limit of quantification [LOQ] values were in the range of 0.03–3.13, and 0.08–9.38 μg/mL, respectively) while the calibration curves were linear with a correlation coefficient (R2) ranging from 0.9966 to 0.9989. The qualitative and quantitative analyses were performed by direct comparison of the peaks of the WCY extract to retention times of reference standards. Additionally, principal component analysis (PCA) successfully discriminated four purchased commercial samples of all six indicator constituents, and the present results indicate their comprehensive potential usefulness for qualitative and quantitative analyses of the WQY decoction and its commercial products.
    Keywords Oriental traditional medicine ; acetonitrile ; active ingredients ; baicalin ; berberine ; calibration ; detection limit ; diodes ; ferulic acid ; formic acid ; high performance liquid chromatography ; principal component analysis ; quantitative analysis ; reference standards ; regression analysis ; wavelengths
    Language English
    Dates of publication 2019-07
    Size p. 749-757.
    Publishing place Elsevier Taiwan LLC.
    Document type Article
    ZDB-ID 1292535-4
    ISSN 1021-9498
    ISSN 1021-9498
    DOI 10.1016/j.jfda.2018.12.003
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  6. Article ; Online: Simultaneous quantification of six indicator compounds in Wen-Qing-Yin by high-performance liquid chromatography-diode array detection.

    Yeh, Chi-Chen / Huang, Shih-Shan / Liu, Po-Yu / Wang, Bo-Cheng / Tsai, Chia-Fen / Wang, Der-Yuan / Cheng, Hwei-Fang

    Journal of food and drug analysis

    2018  Volume 27, Issue 3, Page(s) 749–757

    Abstract: A simple gradient high-performance liquid chromatography with diode array detection (HPLC-DAD) method was used to simultaneously to analyze characteristics of six indicator compounds in the traditional Chinese medicine (TCM) formulation Wen-Qing-Yin (WQY) ...

    Abstract A simple gradient high-performance liquid chromatography with diode array detection (HPLC-DAD) method was used to simultaneously to analyze characteristics of six indicator compounds in the traditional Chinese medicine (TCM) formulation Wen-Qing-Yin (WQY). Separate optimization was performed using a Cosmosil C18 column gradient method with 0.1% formic acid in both mobile phases of aqueous and acetonitrile (ACN), at a flow rate, detection wavelength, and sample volume of 1.8 mL/min, 268 nm, and 10 μL, respectively. The linear regression of six active compounds berberine (BER), baicalin (BAI), ferulic acid (FER), geniposide (GEN), hydorxymethoxylfurfural (HMF), and paeoniflorin (PAE) was produced at the concentration range of 10-2000 μg/mL. The method validation revealed an acceptable precision (intra- and inter-day precision < 3.39% and 4.11%, respectively) and recovery (85.60-110.45% and 86.58-110.90%), a recovery range of 86.61-109.42%, and sensitivity (limit of detection [LOD] and limit of quantification [LOQ] values were in the range of 0.03-3.13, and 0.08-9.38 μg/mL, respectively) while the calibration curves were linear with a correlation coefficient (R
    MeSH term(s) Berberine/analysis ; Chromatography, High Pressure Liquid ; Coumaric Acids/analysis ; Drugs, Chinese Herbal/chemistry ; Flavonoids/analysis ; Furaldehyde/analysis ; Glucosides/analysis ; Iridoids/analysis ; Medicine, Chinese Traditional ; Monoterpenes/analysis
    Chemical Substances Coumaric Acids ; Drugs, Chinese Herbal ; Flavonoids ; Glucosides ; Iridoids ; Monoterpenes ; Berberine (0I8Y3P32UF) ; geniposide (145295QLXY) ; peoniflorin (21AIQ4EV64) ; baicalin (347Q89U4M5) ; ferulic acid (AVM951ZWST) ; Furaldehyde (DJ1HGI319P)
    Language English
    Publishing date 2018-12-28
    Publishing country China (Republic : 1949- )
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2224-6614
    ISSN (online) 2224-6614
    DOI 10.1016/j.jfda.2018.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Book: Special issue dedicated to Professor Ho-Hsiang Wei on the occasion of his 70th birthday and retirement

    Wang, Bo-Cheng / Wang, Wen-Jwu / Wei, Ho-Hsiang

    (Journal of the Chinese Chemical Society ; 57.2010,4B)

    2010  

    Author's details Bo-Cheng Wang; Wen-Jwu Wang [special issue editors]
    Series title Journal of the Chinese Chemical Society ; 57.2010,4B
    Language English
    Size S. 765- 966, Ill., graph. Darst., Tab.
    Publisher Chinese Chemical Society
    Publishing place Taipei
    Document type Book
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

  8. Article ; Online: Edge-termination and core-modification effects of hexagonal nanosheet graphene.

    Deng, Jin-Pei / Chen, Wen-Hao / Chiu, Shou-Po / Lin, Chih-Hsun / Wang, Bo-Cheng

    Molecules (Basel, Switzerland)

    2014  Volume 19, Issue 2, Page(s) 2361–2373

    Abstract: Optimized geometries and electronic structures of two different hexagonal grapheme nanosheets (HGNSs), with armchair (n-A-HGNS, n = 3-11) and zigzag (n-Z-HGNS, n = 1-8) edges have been calculated by using the GGA/PBE method implemented in the SIESTA ... ...

    Abstract Optimized geometries and electronic structures of two different hexagonal grapheme nanosheets (HGNSs), with armchair (n-A-HGNS, n = 3-11) and zigzag (n-Z-HGNS, n = 1-8) edges have been calculated by using the GGA/PBE method implemented in the SIESTA package, with the DZP basis set, where n represents the number of peripheral rings. The computed HOMO-LUMO energy gap (Eg = ELUMO - EHOMO) decreases for fully H-terminated A- and Z-HGNSs with increasing n, i.e., with increasing nanosheet size and pπ-orbitals being widely delocalized over the sheet surface. The full terminations, calculated with various functional groups, including the electron-withdrawing (F-, Cl-, and CN-) and -donating (OH-, and SH-) substitutions, were addressed. Significant lowering of EHOMO and ELUMO was obtained for CN-terminated HGNS as compared to those for H-terminated ones due to the mesomeric effect. The calculated Eg value decreases with increasing n for all terminations, whereby for the SH-termination in HGNS, the termination effect becomes less significant with increasing n. Further, the calculation results for stabilities of HGNS oxides support the tendency toward the oxidative reactivity at the edge site of the sheet, which shows most pronounced C-C bond length alternation, by chemical modification. Physical properties of HGNSs with various numbers of the core-defects, which can be obtained by strong oxidation, were also investigated. Their structures can change drastically from planar to saddle-like shapes. These conformations could be used as stationary phases with controlled interaction in the separation methods such as HPLC and the other chemical analysis techniques.
    MeSH term(s) Electrons ; Graphite/chemistry ; Hydroxides/chemistry ; Models, Chemical ; Nanostructures/chemistry ; Oxides/chemistry
    Chemical Substances Hydroxides ; Oxides ; Graphite (7782-42-5) ; hydroxide ion (9159UV381P)
    Language English
    Publishing date 2014-02-21
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules19022361
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Theoretical interpretations of electronic and fluorescence spectra of new 2(1H)-pyridone derivatives in solution and solid state

    Shigemitsu, Yasuhiro / Hagimori, Masayori / Mizuyama, Naoko / Wang, Bo-Cheng / Tominaga, Yoshinori

    Dyes and pigments. 2013 Dec., v. 99, no. 3

    2013  

    Abstract: A combined experimental and computational study was performed for the spectroscopic properties of novel 2(1H)-pyridones. The compounds were found to be virtually non-fluorescence in solution while modestly fluorescent in solid state. The solvent effects ... ...

    Abstract A combined experimental and computational study was performed for the spectroscopic properties of novel 2(1H)-pyridones. The compounds were found to be virtually non-fluorescence in solution while modestly fluorescent in solid state. The solvent effects on the UV–vis and fluorescence maxima were estimated by means of a series of ab-initio quantum chemical calculations in conjunction with Polarizable Continuum Model (PCM) method. Influence of structural displacements and intermolecular interactions in crystalline state were examined in details on the spectra of two representative compounds by using Fragment Molecular Orbital (FMO) scheme. The FMO pair interaction analysis of the spectra indicate that (1) intermolecular hydrogen bonds provoke bathochromic shifts (2) electrostatic interactions induce hypsochromic shifts (3) crystal packing effects induce hypsochromic shifts in total from the maxima in vacuo.
    Keywords electrostatic interactions ; fluorescence ; hydrogen bonding ; models ; solvents ; spectroscopy
    Language English
    Dates of publication 2013-12
    Size p. 940-949.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0143-7208
    DOI 10.1016/j.dyepig.2013.07.024
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  10. Article: Photophysical properties of arylcarbonitrile derivatives: Synthesis, absorption and emission spectra, and quantum chemical studies

    Shigemitsu, Yasuhiro / Wang, Bo-Cheng / Nishimura, Yasuhisa / Tominaga, Yoshinori

    Dyes and pigments. 2012 Jan., v. 92, no. 1

    2012  

    Abstract: A new series of aromatic cyanovinyl compounds were synthesized via one-pot reactions of tri- or tetracyanoethylenes with nucleophilic reagents. The ground-state geometries and UV–vis absorption spectra of the compounds were computationally analyzed by ... ...

    Abstract A new series of aromatic cyanovinyl compounds were synthesized via one-pot reactions of tri- or tetracyanoethylenes with nucleophilic reagents. The ground-state geometries and UV–vis absorption spectra of the compounds were computationally analyzed by means of density functional theory (DFT) and time-dependent density functional theory (TDDFT) calculations, respectively. None of the compounds were fluorescent in solution, but some showed intense emission in the solid state. The first excited singlet states (S₁) potential energy surfaces (PESs) were explored using complete active space SCF (CASSCF) calculations for the compounds in order to elucidate nonradiative decay mechanism that takes into account the involvement of conical intersections (CI).
    Keywords absorption ; energy ; fluorescence
    Language English
    Dates of publication 2012-01
    Size p. 580-587.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0143-7208
    DOI 10.1016/j.dyepig.2011.06.015
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

To top