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  1. Article ; Online: Review of "Artificial Intelligence-enabled Decision Support in Surgery: State-of-the-art and Future Directions" by Loftus et al. Annals of Surgery 2023;278(1):51-58.

    Wang, Daniel S / Hollier, Larry H

    The Journal of craniofacial surgery

    2023  Volume 35, Issue 1, Page(s) 273

    MeSH term(s) Humans ; Artificial Intelligence ; Algorithms ; Forecasting
    Language English
    Publishing date 2023-08-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000009674
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    Zs.A 3761: Show issues Location:
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  2. Article ; Online: Review of "Professional Coaching and Surgeon Well-Being: A Randomized Controlled Trial" by Dyrbye LN, Gill PR, Satele DV, West CP. Annals of Surgery 2023;277:565-571.

    Wang, Daniel S / Hollier, Larry H

    The Journal of craniofacial surgery

    2023  Volume 34, Issue 7, Page(s) 2232

    MeSH term(s) Animals ; Humans ; Mentoring ; Gills ; Surgeons
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Comment
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000009587
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  3. Article ; Online: Familiar Faces: Fostering a Patient-Provider Alliance.

    Wang, Daniel / Suarez, Maria Victoria

    Academic medicine : journal of the Association of American Medical Colleges

    2022  Volume 98, Issue 6, Page(s) 657

    Language English
    Publishing date 2022-09-13
    Publishing country United States
    Document type Letter
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000004977
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    Zs.A 112: Show issues Location:
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  4. Article ; Online: Recurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension.

    Fish, Adam / Wang, Daniel / Knight, Elizabeth / Pollak, Jeffrey / Schlachter, Todd

    Journal of vascular and interventional radiology : JVIR

    2024  

    Abstract: Purpose: To evaluate the correlation between pulmonary hypertension (PH) and post-embolization pulmonary arteriovenous malformation (PAVM) recurrence.: Materials and methods: With IRB approval the records of 377 patients with PAVMs evaluated at ... ...

    Abstract Purpose: To evaluate the correlation between pulmonary hypertension (PH) and post-embolization pulmonary arteriovenous malformation (PAVM) recurrence.
    Materials and methods: With IRB approval the records of 377 patients with PAVMs evaluated at single HHT center of excellence between January 1, 2013, and September 10, 2023, were retrospectively reviewed. PAVMs embolized during this time-period were evaluated for recurrence. Patients and PAVMs not treated during this time-period were excluded. Growth of previously untreated PAVMs was not considered recurrence. Patients without chest CT follow-up were excluded. General demographics, HHT status as defined by genetic testing or Curacao criteria, presence of PH, history of smoking, anemia, and liver AVMs was documented. Odds ratio and stratified analysis was calculated to assay the correlation between PAVM recurrence, PH and possible confounders.
    Results: A total of 151 patients with PAVMs were treated during the study period, including 438 PAVMs, for which follow-up was available. This included 106 patients with definite, 31 doubtful, and 14 possible HHT. The presence of pulmonary hypertension was significantly associated with both PAVM recurrence by patient (OR: 8.13, 95% CI 3.50 - 19.67) and by lesion (OR: 4.07, 95% CI 2.14 - 7.91). Multivariate analysis demonstrated that this correlation was independent of several variables including HHT status, smoking history, presence of liver AVMs, and anemia.
    Conclusion: There is a high correlation between pulmonary hypertension and PAVM recurrence, likely due to high pulmonary artery pressures causing recanalization. Pulmonary hypertension may suggest the need for shorter surveillance intervals.
    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/j.jvir.2024.04.017
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    Zs.A 3720: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Article ; Online: Withdrawing treatment from patients with prolonged disorders of consciousness: the wrong answer is what the wrong question begets.

    Wang, Daniel Wei Liang

    Journal of medical ethics

    2020  Volume 46, Issue 8, Page(s) 561–562

    Abstract: In a recent paper, Charles Foster argued that the epistemic uncertainties surrounding prolonged disorders of consciousness (PDOC) make it impossible to prove that the withdrawal of life-sustaining treatment can be in a patient's best interests and, ... ...

    Abstract In a recent paper, Charles Foster argued that the epistemic uncertainties surrounding prolonged disorders of consciousness (PDOC) make it impossible to prove that the withdrawal of life-sustaining treatment can be in a patient's best interests and, therefore, the presumption in favour of the maintenance of life cannot be rebutted. In the present response, I argue that, from a legal perspective, Foster has reached the wrong conclusion because he is asking the wrong question. According to the reasoning in two leading cases
    MeSH term(s) Consciousness ; Humans ; Life Support Care ; Morals ; Uncertainty ; Withholding Treatment
    Language English
    Publishing date 2020-02-13
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 194927-5
    ISSN 1473-4257 ; 0306-6800
    ISSN (online) 1473-4257
    ISSN 0306-6800
    DOI 10.1136/medethics-2020-106063
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  6. Article: A 55-Year-Old Male With Systemic Gout Complicated by Septic Shock.

    Garza, Jay E / Nguyen, Quoc-Bao / Wang, Daniel V

    Cureus

    2023  Volume 15, Issue 6, Page(s) e40764

    Abstract: Tophaceous gout is the systemic deposition of uric acid which can induce cutaneous ulceration. We present the case of a 55-year-old male with chronic tophaceous gout whose initial presentation was complicated by septic shock due to methicillin- ... ...

    Abstract Tophaceous gout is the systemic deposition of uric acid which can induce cutaneous ulceration. We present the case of a 55-year-old male with chronic tophaceous gout whose initial presentation was complicated by septic shock due to methicillin-sensitive
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.40764
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  7. Article: Case Report: Early diagnosis and bevacizumab-based chemotherapy for primary pericardial mesothelioma: a case with occupational asbestos exposure history.

    Wang, Daniel / Wang, Yung Hsuan / Chu, Sung Chao

    Frontiers in cardiovascular medicine

    2023  Volume 10, Page(s) 1257373

    Abstract: Background: Primary pericardial mesothelioma (PPM) is an exceedingly rare malignant cancer and has a poor prognosis, which has been partly attributed to its frequently delayed diagnosis due to its nonspecific syndromes, its similar presentation to ... ...

    Abstract Background: Primary pericardial mesothelioma (PPM) is an exceedingly rare malignant cancer and has a poor prognosis, which has been partly attributed to its frequently delayed diagnosis due to its nonspecific syndromes, its similar presentation to benign pericardial diseases, and its non-definitive etiology. In many PPM cases, the time from presentation to definite diagnosis may last for several months or even over one year. Unlike pleural mesothelioma, the relationship between PPM and asbestos exposure remains unsettled. To date, there is no consensus on the treatment of PPM.
    Case report: The patient is a 57-year-old male who had nonspecific syndromes and inconclusive image findings. The occupational long-term asbestos exposure history of this patient raised our concerns regarding potential malignancy when confronted with unexplained pericardial effusion accompanied by cardiac tamponade. The heightened suspicion prompted us to perform pericardiocentesis and biopsy on the third day after admission to our department. An early diagnosis of PPM was established by the pathological and immunohistochemical evaluation of the biopsy specimen two weeks after admission. Positron emission tomography-computed tomography revealed that the lesion was localized at the anterior part of the mediastinum without distant metastasis. This patient refused to receive cardiac surgery. He subsequently underwent six cycles of chemotherapy (cisplatin plus pemetrexed) in combination with bevacizumab (a humanized anti-VEGF antibody) as the first-line treatment, resulting in complete relief of symptoms and satisfactory outcomes with no complications. Four months after the first course, the patient initiated a second course of chemotherapy with a similar regimen, but he opted to discontinue the medical treatment after the initiation of the second course. The patient was transferred to the hospice care unit and unfortunately expired one year after the initial presentation.
    Conclusion: We present a case of an early multidisciplinary clinical approach to diagnose and manage PPM with consideration of occupational asbestos exposure history and clinical symptoms. Bevacizumab-based chemotherapy remains an option for the treatment of PPM.
    Language English
    Publishing date 2023-11-20
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1257373
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  8. Article ; Online: Traumatic Obturator Hip Dislocation in a 9-Year-Old Girl: A Case Report.

    Wang, Daniel D / Bora, Varun G / Beauvais, Dorothy H

    JBJS case connector

    2023  Volume 13, Issue 2

    Abstract: Case: We present a case of traumatic anterior obturator hip dislocation in a pediatric patient with a focus on acute management of this injury. The orthopaedic team successfully performed closed reduction of this injury on an emergent basis, and the ... ...

    Abstract Case: We present a case of traumatic anterior obturator hip dislocation in a pediatric patient with a focus on acute management of this injury. The orthopaedic team successfully performed closed reduction of this injury on an emergent basis, and the patient had minimal issues with ambulation and pain at subsequent follow-up.
    Conclusion: Pediatric traumatic hip dislocations are rare injuries with potentially devastating sequelae, particularly if diagnosis and treatment are delayed. Proper technique during closed reduction is essential. Be prepared for potential emergent open reduction. Two years of postinjury follow-up is recommended to monitor for signs of femoral head osteonecrosis.
    MeSH term(s) Female ; Humans ; Child ; Hip Dislocation/diagnostic imaging ; Hip Dislocation/surgery ; Hip Dislocation/complications ; Open Fracture Reduction/adverse effects ; Plastic Surgery Procedures ; Femur Head/injuries
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2160-3251
    ISSN (online) 2160-3251
    DOI e22.00795
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  9. Article ; Online: Rhegmatogenous retinal detachment surgery: A review.

    Warren, Alexis / Wang, Daniel W / Lim, Jennifer I

    Clinical & experimental ophthalmology

    2023  Volume 51, Issue 3, Page(s) 271–279

    Abstract: Rhegmatogenous retinal detachment (RRD) is a serious surgical condition with significant ocular morbidity if not managed properly. Once untreatable, approaches to the repair of RRD have greatly evolved over the years, leading to outstanding primary ... ...

    Abstract Rhegmatogenous retinal detachment (RRD) is a serious surgical condition with significant ocular morbidity if not managed properly. Once untreatable, approaches to the repair of RRD have greatly evolved over the years, leading to outstanding primary surgical success rates. The management of RRD is often a topic of great debate. Scleral buckling, vitrectomy and pneumatic retinopexy have been used successfully for the treatment of RRD. Several factors may affect surgical success and dictate a surgeon's preference for the technique employed. In this review, we provide an overview and supporting literature on the options for RRD repair and their respective preoperative and postoperative considerations in order to guide surgical management.
    MeSH term(s) Humans ; Retinal Detachment/surgery ; Treatment Outcome ; Scleral Buckling/methods ; Retina ; Vitrectomy/methods ; Retrospective Studies
    Language English
    Publishing date 2023-01-25
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2014008-3
    ISSN 1442-9071 ; 1442-6404
    ISSN (online) 1442-9071
    ISSN 1442-6404
    DOI 10.1111/ceo.14205
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    Zs.A 1064: Show issues Location:
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  10. Article ; Online: Priority-setting for hospital funding of high-cost innovative drugs and therapeutics: A qualitative institutional case study.

    Razvi, Yasmeen / Horwitz, Simonne L / Cressman, Celine / Wang, Daniel E / Shaul, Randi Zlotnik / Denburg, Avram

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0300519

    Abstract: Objectives: Rising costs of innovative drugs and therapeutics (D&Ts) have led to resource allocation challenges for healthcare institutions. There is limited evidence to guide priority-setting for institutional funding of high-cost D&Ts. This study ... ...

    Abstract Objectives: Rising costs of innovative drugs and therapeutics (D&Ts) have led to resource allocation challenges for healthcare institutions. There is limited evidence to guide priority-setting for institutional funding of high-cost D&Ts. This study sought to identify and elaborate on the substantive principles and procedures that should inform institutional funding decisions for high-cost off-formulary D&Ts through a case study of a quaternary care paediatric hospital.
    Methods: Semi-structured, qualitative interviews, both virtual and in-person, were conducted with institutional stakeholders (i.e. staff clinicians, senior leadership, and pharmacists) (n = 23) and two focus groups at The Hospital for Sick Children in Toronto, Canada. Participants involved in, and impacted by, high-cost off-formulary drug funding decisions were recruited through stratified, purposive sampling. Participants were approached for study involvement between July 27, 2020 and June 7, 2022. Data was analysed through reflexive thematic analysis.
    Results: Institutional resource allocation for high-cost D&Ts was identified as ethically challenging but critical to sustainable access to novel therapies. Important substantive principles included: 1) clinical evidence of safety and efficacy, 2) economic considerations (direct costs, opportunity costs, value for money), 3) ethical principles (social justice, professional/organizational responsibility), and 4) disease-specific considerations. Multidisciplinary deliberation was identified as an essential procedural component of decision-making. Participants identified tension between innovation and the need for evidence-based decision-making; clinician and institutional responsibilities; and value for money and social justice. Participants emphasized the role of health system-level funding allocation in alleviating the financial and moral burden of decision-making by institutions.
    Conclusions: This study identifies values and processes to aid in the development and implementation of institutional resource allocation frameworks for high-cost innovative D&Ts.
    MeSH term(s) Humans ; Child ; Hospitals ; Resource Allocation ; Research Design ; Qualitative Research ; Canada
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0300519
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