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Article ; Online: Management of interstitial pregnancy using laparoscopic salpingectomy with complete removal of the interstitial portion.

Wang, Shengke / Wang, Dongdong

2023 Volume 119, Issue 5, Page(s) 889–891

Abstract: Objective: To perform laparoscopic salpingectomy, including the entire interstitial portion of the fallopian tube, in the management of interstitial pregnancy.: Design: A step-by-step explanation of the surgical procedure using video with narration.!# ...

Abstract	Objective: To perform laparoscopic salpingectomy, including the entire interstitial portion of the fallopian tube, in the management of interstitial pregnancy. Design: A step-by-step explanation of the surgical procedure using video with narration. Setting: Obstetrics and Gynecology department of a hospital. Patient(s): A 23-year-old woman, gravida 1 para 0, presented asymptomatically to our hospital to undergo a pregnancy test. Her last menstrual period had occurred 6 weeks previously. Transvaginal ultrasound showed an empty uterine cavity and a right interstitial mass of 3.2 × 2.6 × 2.5 cm. It contained a chorionic sac and an embryonic bud of 0.2 cm long with a heartbeat and the presence of an "interstitial line sign." The myometrial layer surrounding the chorionic sac was 1 mm. The patient's beta-human chorionic gonadotropin level was 10,123 mIU/mL. Intervention(s): On the basis of the anatomy of the interstitial portion of the fallopian tube, we treated interstitial pregnancy using laparoscopic salpingectomy, with complete removal of the interstitial portion containing the product of conception. The interstitial fallopian tube originates at the tubal ostium and follows a tortuous intramural course, progressing laterally away from the uterine cavity toward the isthmic portion. It is lined by muscular layers and an inner epithelium layer. The main blood supply of the interstitial portion is from the uterine artery's ascending branches to the fundus, extending a branch that supplies the cornu and the interstitial portion. Our approach has 3 key steps: 1) dissecting and coagulating the branch extending from the ascending branches to the fundus of the uterine artery, 2) incising the cornual serosa at the junction of the purple-blue interstitial pregnancy and the normal color myometrium, and 3) resecting the interstitial portion containing the product of conception along the outer layer of the oviduct without rupture. Main outcome measure(s): The interstitial portion containing the product of conception was removed entirely along the outer layer of the fallopian tube as a natural capsule without rupture. Results(s): The surgery lasted for 43 min, and the volume of intraoperative blood loss was 5 mL. The pathology was confirmatory for interstitial pregnancy. The patient's beta-human chorionic gonadotropin levels decreased optimally. She had a normal postoperative course. Conclusion(s): This approach reduces intraoperative blood loss, minimizes myometrial loss and thermal injury, and effectively avoids persistent interstitial ectopic pregnancy. It is not limited by the device used, does not increase the surgery cost, and is greatly useful in treating a selected nonruptured distally or centrally implanted interstitial pregnancy.
MeSH term(s)	Humans ; Pregnancy ; Female ; Young Adult ; Adult ; Pregnancy, Interstitial/diagnostic imaging ; Pregnancy, Interstitial/surgery ; Laparoscopy/methods ; Blood Loss, Surgical ; Salpingectomy/methods ; Chorionic Gonadotropin, beta Subunit, Human
Chemical Substances	Chorionic Gonadotropin, beta Subunit, Human
Language	English
Publishing date	2023-03-05
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80133-1
ISSN	1556-5653 ; 0015-0282
ISSN (online)	1556-5653
ISSN	0015-0282
DOI	10.1016/j.fertnstert.2023.02.041
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Article ; Online: Insights into vehicle conflicts based on traffic flow dynamics.

Ding, Shengxuan / Abdel-Aty, Mohamed / Wang, Zijin / Wang, Dongdong

Scientific reports

2024 Volume 14, Issue 1, Page(s) 1536

Abstract: The utilization of traffic conflict indicators is crucial for assessing traffic safety, especially when the crash data is unavailable. To identify traffic conflicts based on traffic flow characteristics across various traffic states, we propose a ... ...

Abstract	The utilization of traffic conflict indicators is crucial for assessing traffic safety, especially when the crash data is unavailable. To identify traffic conflicts based on traffic flow characteristics across various traffic states, we propose a framework that utilizes unsupervised learning to automatically establish surrogate safety measures (SSM) thresholds. Different traffic states and corresponding transitions are identified with the three-phase traffic theory using high-resolution trajectory data. Meanwhile, the SSMs are mapped to the corresponding traffic states from the perspectives of time, space, and deceleration. Three models, including k-means, GMM, and Mclust, are investigated and compared to optimize the identification of traffic conflicts. It is observed that Mclust outperforms the others based on the evaluation metrics. According to the results, there is a variation in the distribution of traffic conflicts among different traffic states, wide moving jam (phase J) has the highest conflict risk, followed by synchronous flow (phase S), and free flow (phase F). Meanwhile, the thresholds of traffic conflicts cannot be fully represented by the same value through different traffic states. It reveals that the heterogeneity of thresholds is exhibited across traffic state transitions, which justifies the necessity of dynamic thresholds for traffic conflict analysis.
Language	English
Publishing date	2024-01-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-50017-3
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Article ; Online: Unveiling terahertz wave stress effects and mechanisms in Pinellia ternata: Challenges, insights, and future directions.

Wang, Dongdong / Zheng, Jiatong / Sarsaiya, Surendra / Jin, Leilei / Chen, Jishuang

Physiologia plantarum

2024 Volume 176, Issue 1, Page(s) e14195

Abstract: This review aims to elucidate the intricate effects and mechanisms of terahertz (THz) wave stress on Pinellia ternata, providing valuable insights into plant responses. The primary objective is to highlight the imperative for future research dedicated to ...

Abstract	This review aims to elucidate the intricate effects and mechanisms of terahertz (THz) wave stress on Pinellia ternata, providing valuable insights into plant responses. The primary objective is to highlight the imperative for future research dedicated to comprehending THz wave impacts across plant structures, with a specific focus on the molecular intricacies governing root system structure and function, from shoots to roots. Notably, this review highlights the accelerated plant growth induced by THz waves, especially in conjunction with other environmental stressors, and the subsequent alterations in cellular homeostasis, resulting in the generation of reactive oxygen species (ROS) and an increase in brassinosteroids. Brassinosteroids are explored for their dual role as toxic by-products of stress metabolism and vital signal transduction molecules in plant responses to abiotic stresses. The paper further investigates the spatio-temporal regulation and long-distance transport of phytohormones, including growth hormone, cytokinin, and abscisic acid (ABA), which significantly influence the growth and development of P. ternata under THz wave stress. With a comprehensive review of Reactive oxygen species (ROS) and Brassinosteroid Insensitive (BRI) homeostasis and signalling under THz wave stress, the article elucidates the current understanding of BRI involvement in stress perception, stress signalling, and domestication response regulation. Additionally, it underscores the importance of spatio-temporal regulation and long-distance transport of key plant hormones, such as growth hormone, cytokinin, and ABA, in determining root growth and development under THz wave stress. The study of how plants perceive and respond to environmental stresses holds fundamental biological significance, and enhancing plant stress tolerance is crucial for promoting sustainable agricultural practices and mitigating the environmental burdens associated with low-tolerance crop cultivation.
MeSH term(s)	Brassinosteroids/metabolism ; Reactive Oxygen Species/metabolism ; Pinellia/metabolism ; Plant Growth Regulators/metabolism ; Abscisic Acid/metabolism ; Stress, Physiological ; Cytokinins/metabolism ; Plants/metabolism ; Growth Hormone/metabolism ; Growth Hormone/pharmacology
Chemical Substances	Brassinosteroids ; Reactive Oxygen Species ; Plant Growth Regulators ; Abscisic Acid (72S9A8J5GW) ; Cytokinins ; Growth Hormone (9002-72-6)
Language	English
Publishing date	2024-02-08
Publishing country	Denmark
Document type	Journal Article ; Review
ZDB-ID	2020837-6
ISSN	1399-3054 ; 0031-9317
ISSN (online)	1399-3054
ISSN	0031-9317
DOI	10.1111/ppl.14195
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Article ; Online: Ultrafast restricted intramolecular rotation in molecules with aggregation induced emission.

Hu, Xiao / Wang, Dongdong / Wang, Yanmei / Wang, Ye / Zhang, Song

The Journal of chemical physics

2024 Volume 160, Issue 15

Abstract: In this work, the ultrafast intramolecular rotation behavior of 1,1,2,3,4,5-hexaphenylsilole has been investigated in several solutions with different viscosities using femtosecond transient absorption spectroscopy combined with density functional theory ...

Abstract	In this work, the ultrafast intramolecular rotation behavior of 1,1,2,3,4,5-hexaphenylsilole has been investigated in several solutions with different viscosities using femtosecond transient absorption spectroscopy combined with density functional theory and time-dependent density functional theory calculations. It is demonstrated that the nonradiative process, which competes with radiative decay, involves two main stages, namely the restricted intramolecular rotation and internal conversion processes. The intramolecular rotation depends on viscosity and presents a significant restriction. The restricted rotational rate is determined to be dozens of picoseconds. The following nonradiative process is strongly dominated by intramolecular rotation. The nonradiative decay rate will decrease with the increase in viscosity, leading to a rise in the radiative probability and photoluminous yield. These results have borne out the mechanism of ultrafast restricted intramolecular rotation of aggregation induced emission and provided a detailed photophysical picture of nonradiative processes.
Language	English
Publishing date	2024-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	3113-6
ISSN	1089-7690 ; 0021-9606
ISSN (online)	1089-7690
ISSN	0021-9606
DOI	10.1063/5.0200622
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Article ; Online: Selective Electrocatalytic Conversion of Nitric Oxide to High Value-Added Chemicals.

Wang, Dongdong / Lu, Xue Feng / Luan, Deyan / Lou, Xiong Wen David

Advanced materials (Deerfield Beach, Fla.)

2024 Volume 36, Issue 18, Page(s) e2312645

Abstract: The artificial disturbance in the nitrogen cycle has necessitated an urgent need for nitric oxide (NO) removal. Electrochemical technologies for NO conversion have gained increasing attention in recent years. This comprehensive review presents the recent ...

Abstract	The artificial disturbance in the nitrogen cycle has necessitated an urgent need for nitric oxide (NO) removal. Electrochemical technologies for NO conversion have gained increasing attention in recent years. This comprehensive review presents the recent advancements in selective electrocatalytic conversion of NO to high value-added chemicals, with specific emphasis on catalyst design, electrolyte composition, mass diffusion, and adsorption energies of key intermediate species. Furthermore, the review explores the synergistic electrochemical co-electrolysis of NO with specific carbon source molecules, enabling the synthesis of a range of valuable chemicals with C─N bonds. It also provides in-depth insights into the intricate reaction pathways and underlying mechanisms, offering valuable perspectives on the challenges and prospects of selective NO electrolysis. By advancing comprehension and fostering awareness of nitrogen cycle balance, this review contributes to the development of efficient and sustainable electrocatalytic systems for the selective synthesis of valuable chemicals from NO.
Language	English
Publishing date	2024-02-05
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	1474949-X
ISSN	1521-4095 ; 0935-9648
ISSN (online)	1521-4095
ISSN	0935-9648
DOI	10.1002/adma.202312645
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Article ; Online: Real-time crash prediction on express managed lanes of Interstate highway with anomaly detection learning.

Yang, Samgyu / Abdel-Aty, Mohamed / Islam, Zubayer / Wang, Dongdong

Accident; analysis and prevention

2024 Volume 201, Page(s) 107568

Abstract: To facilitate efficient transportation, I-4 Express is constructed separately from general use lanes in metropolitan area to improve mobility and reduce congestion. As this new infrastructure would undoubtedly change the traffic network, there is a need ... ...

Abstract	To facilitate efficient transportation, I-4 Express is constructed separately from general use lanes in metropolitan area to improve mobility and reduce congestion. As this new infrastructure would undoubtedly change the traffic network, there is a need for more understanding of its potential safety impact. Unfortunately, many advanced real-time crash prediction models encounter an important challenge in their applicability due to their demand for a substantial volume of data for direct modeling. To tackle this challenge, we proposed a simple yet effective approach - anomaly detection learning, which formulates model as an anomaly detection problem, solves it through normality feature recognition, and predicts crashes by identifying deviations from the normal state. The proposed approach demonstrates significant improvement in the Area Under the Curve (AUC), sensitivity, and False Alarm Rate (FAR). When juxtaposed with the prevalent direct classification paradigm, our proposed anomaly detection learning (ADL) consistently outperforms in AUC (with an increase of up to 45%), sensitivity (experiencing up to a 45% increase), and FAR (reducing by up to 0.53). The most performance gain is attained through the combination of Convolutional Neural Network (CNN) and Long Short-Term Memory (LSTM) in an ensemble, resulting in a 0.78 AUC, 0.79 sensitivity, and a 0.22 false alarm rate. Furthermore, we analyzed model features with a game-theoretic approach illustrating the most correlated features for accurate prediction, revealing the attention of advanced convolution neural networks to occupancy features. This provided crucial insights into improving crash precaution, the findings from which not only benefit private stakeholders but also extend a promising opportunity for governmental intervention on the express lane. This work could promote express lane with more efficient resource allocation, real-time traffic management optimization, and high-risk area prioritization.
MeSH term(s)	Humans ; Accidents, Traffic/prevention & control ; Accidents, Traffic/statistics & numerical data ; Neural Networks, Computer ; Automobile Driving ; Environment Design ; Area Under Curve ; Machine Learning
Language	English
Publishing date	2024-04-05
Publishing country	England
Document type	Journal Article
ZDB-ID	210223-7
ISSN	1879-2057 ; 0001-4575
ISSN (online)	1879-2057
ISSN	0001-4575
DOI	10.1016/j.aap.2024.107568
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Zs.A 2461: Show issues

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Article ; Online: Spectral Analysis on Cuba-Lumacaftor: Cubane as Benzene Bioisosteres of Lumacaftor.

Wang, Dongdong / Lyu, Xiaohong / Sun, Mengtao / Liang, Yongqiang

ACS omega

2023 Volume 8, Issue 45, Page(s) 43332–43340

Abstract: In this paper, we theoretically investigate the electronic structure and physical properties of cuba-lumacaftor, cubane as benzene bioisosteres of lumacaftor, stimulated by recent experimental reports [Wiesenfeldt M. P.; Nature2023, 618, 513-518]. The ... ...

Abstract	In this paper, we theoretically investigate the electronic structure and physical properties of cuba-lumacaftor, cubane as benzene bioisosteres of lumacaftor, stimulated by recent experimental reports [Wiesenfeldt M. P.; Nature2023, 618, 513-518]. The permanent electric dipole moments of cuba-lumacaftor in neutral, acidic, and alkaline environments are significantly enlarged than that of lumacaftor, significantly promoting the interaction between cuba-lumacaftor and surrounding polar solvent environments and resulting in pH-independent high solubility and pharmacological activity. Furthermore, electronic circular dichroism (ECD) spectra reveal that the chirality of cuba-lumacaftor is much decreased compared to that of lumacaftor. Raman spectra and resonance Raman spectra combined with polarizability also reveal the vibrational information on cuba-lumacaftor. Our results promote a deeper understanding of better pharmacological activity.
Language	English
Publishing date	2023-11-03
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.3c07532
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Article ; Online: Influence of the Long-Range Transport of Siberian Biomass Burnings on Air Quality in Northeast China in June 2017.

Sun, Li / Yang, Lei / Wang, Dongdong / Zhang, Tiening

Sensors (Basel, Switzerland)

2023 Volume 23, Issue 2

Abstract: Biomass burning (BB) emits a large volume of trace gases and aerosols into the atmosphere, which can significantly affect the earth's radiative balance and climate and has negative impacts on air quality and even human health. In late June 2017, an ... ...

Abstract	Biomass burning (BB) emits a large volume of trace gases and aerosols into the atmosphere, which can significantly affect the earth's radiative balance and climate and has negative impacts on air quality and even human health. In late June 2017, an intense BB case, dominated by forest and savanna fires, occurred in Siberia, and it affected the air quality of Northeast China through long-range transport. Here, multisatellite remote-sensing products and ground-based PM
MeSH term(s)	Humans ; Air Pollutants/analysis ; Biomass ; Environmental Monitoring/methods ; Air Pollution/analysis ; China ; Fires ; Aerosols ; Particulate Matter/analysis ; Seasons
Chemical Substances	Air Pollutants ; Aerosols ; Particulate Matter
Language	English
Publishing date	2023-01-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23020682
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Article: Risk factors, prognostic potency, and longitudinal variation of anxiety and depression in postoperative glioma patients.

Wu, Xiaohua / Wang, Dongdong / Wang, Dan

Frontiers in surgery

2023 Volume 9, Page(s) 1069709

Abstract: Objective: Anxiety and depression are common mental disorders in glioma patients. This study aimed to evaluate the risk factors, prognostic role, and longitudinal changes in anxiety and depression in postoperative glioma patients.: Methods: Anxiety ... ...

Abstract	Objective: Anxiety and depression are common mental disorders in glioma patients. This study aimed to evaluate the risk factors, prognostic role, and longitudinal changes in anxiety and depression in postoperative glioma patients. Methods: Anxiety and depression were assessed by Hospital Anxiety and Depression Scale at baseline, month (M) 6, M12, M24 and M36 in 270 glioma patients after surgical resection. Furthermore, comprehensive clinic characteristics and treatment-related information were collected. Results: Gender (female vs. male) ( Conclusion: Gender, marital status, KPS score, WHO classification, and postoperative complications are risk factors for anxiety and depression; moreover, anxiety and depression are at high prevalence continuously and correlated with worse survival in postoperative glioma patients.
Language	English
Publishing date	2023-01-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2773823-1
ISSN	2296-875X
ISSN	2296-875X
DOI	10.3389/fsurg.2022.1069709
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Article ; Online: Observation of hemostatic effectiveness and safety of ultrasound-CT guided 3D intracavitary and interstitial brachytherapy in the treatment of larger cervical cancer with bleeding: A retrospective study.

Hu, Yuefeng / Jin, Ying / Wang, Dongdong / Luo, Yunxiu

Medicine

2023 Volume 102, Issue 37, Page(s) e34904

Abstract: Cervical cancer is the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women. This study explored the effectiveness and safety of ultrasound-CT guided 3D intracavitary and interstitial brachytherapy (US-CT-3D-IGBT) ...

Abstract	Cervical cancer is the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women. This study explored the effectiveness and safety of ultrasound-CT guided 3D intracavitary and interstitial brachytherapy (US-CT-3D-IGBT) in the treatment of larger cervical cancer with bleeding. A retrospective study was conducted on 31 patients with larger cervical squamous cell carcinoma (tumor short diameter >4 cm) with vaginal bleeding. US-CT-3D-IGBT was used to deliver a single high-dose prescription of high-risk clinical target volume (HR-CTV) 1000 to 1200 centigray (cGy) to the cervical tumor, followed by conventional intensity-modulated radiation therapy (IMRT) synchronous chemoradiotherapy (45-50 gray (Gy)/25-28 fraction(f)) with weekly cisplatin 25 mg/m2. After external radiotherapy, simple intracavitary brachytherapy (BT) combined with manual interstitial BT was administered at 30 Gy/5F or 28 Gy/4F. Within 24 hours after high-dose 3D-IGBT, bleeding stopped in 2 patients (6.4%), and bleeding was reduced in a total of 11 patients (35.4%) within 48 hours. A total of 29 patients achieved hemostasis within 72 hours, with an effective rate of 93.5%. The remaining 2 patients reached the clinical hemostasis requirement on the 4th and 5th day. All patients experienced a significant reduction in vaginal bleeding after the initial BT, with an average reduction of 66 mL (160-20 mL). US-CT-3D-IGBT is effective in rapidly controlling bleeding in patients with larger cervical cancer (tumor short diameter >4 cm), and the treatment is relatively safe and feasible.
MeSH term(s)	Humans ; Female ; Uterine Cervical Neoplasms/radiotherapy ; Hemostatics ; Retrospective Studies ; Brachytherapy ; Uterine Hemorrhage/etiology ; Hemostasis ; Tomography, X-Ray Computed
Chemical Substances	Hemostatics
Language	English
Publishing date	2023-09-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000034904
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