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  1. Article ; Online: Continual Reinforcement Learning for Quadruped Robot Locomotion.

    Gai, Sibo / Lyu, Shangke / Zhang, Hongyin / Wang, Donglin

    Entropy (Basel, Switzerland)

    2024  Volume 26, Issue 1

    Abstract: The ability to learn continuously is crucial for a robot to achieve a high level of intelligence and autonomy. In this paper, we consider continual reinforcement learning (RL) for quadruped robots, which includes the ability to continuously learn sub- ... ...

    Abstract The ability to learn continuously is crucial for a robot to achieve a high level of intelligence and autonomy. In this paper, we consider continual reinforcement learning (RL) for quadruped robots, which includes the ability to continuously learn sub-sequential tasks (plasticity) and maintain performance on previous tasks (stability). The policy obtained by the proposed method enables robots to learn multiple tasks sequentially, while overcoming both catastrophic forgetting and loss of plasticity. At the same time, it achieves the above goals with as little modification to the original RL learning process as possible. The proposed method uses the Piggyback algorithm to select protected parameters for each task, and reinitializes the unused parameters to increase plasticity. Meanwhile, we encourage the policy network exploring by encouraging the entropy of the soft network of the policy network. Our experiments show that traditional continual learning algorithms cannot perform well on robot locomotion problems, and our algorithm is more stable and less disruptive to the RL training progress. Several robot locomotion experiments validate the effectiveness of our method.
    Language English
    Publishing date 2024-01-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e26010093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: A General Offline Reinforcement Learning Framework for Interactive Recommendation

    Xiao, Teng / Wang, Donglin

    2023  

    Abstract: This paper studies the problem of learning interactive recommender systems from logged feedbacks without any exploration in online environments. We address the problem by proposing a general offline reinforcement learning framework for recommendation, ... ...

    Abstract This paper studies the problem of learning interactive recommender systems from logged feedbacks without any exploration in online environments. We address the problem by proposing a general offline reinforcement learning framework for recommendation, which enables maximizing cumulative user rewards without online exploration. Specifically, we first introduce a probabilistic generative model for interactive recommendation, and then propose an effective inference algorithm for discrete and stochastic policy learning based on logged feedbacks. In order to perform offline learning more effectively, we propose five approaches to minimize the distribution mismatch between the logging policy and recommendation policy: support constraints, supervised regularization, policy constraints, dual constraints and reward extrapolation. We conduct extensive experiments on two public real-world datasets, demonstrating that the proposed methods can achieve superior performance over existing supervised learning and reinforcement learning methods for recommendation.

    Comment: AAAI2021
    Keywords Computer Science - Machine Learning ; Computer Science - Information Retrieval
    Subject code 006
    Publishing date 2023-10-01
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Mitigating microbiological risks of potential pathogens carrying antibiotic resistance genes and virulence factors in receiving rivers: Benefits of wastewater treatment plant upgrade

    Mao, Guannan / Wang, Donglin / Bai, Yaohui / Qu, Jiuhui

    Front. Environ. Sci. Eng.. 2023 July, v. 17, no. 7 p.82-82

    2023  

    Abstract: Wastewater treatment plants (WWTPs) with additional tertiary ultrafiltration membranes and ozonation treatment can improve water quality in receiving rivers. However, the impacts of WWTP upgrade (WWTP-UP) on pathogens carrying antibiotic resistance genes ...

    Abstract Wastewater treatment plants (WWTPs) with additional tertiary ultrafiltration membranes and ozonation treatment can improve water quality in receiving rivers. However, the impacts of WWTP upgrade (WWTP-UP) on pathogens carrying antibiotic resistance genes (ARGs) and virulence factors (VFs) in rivers remain poorly understood. In this study, ARGs, VFs, and their pathogenic hosts were investigated in three rivers impacted by large-scale WWTP-UP. A five-year sampling campaign covered the periods before and after WWTP-UP. Results showed that the abundance of total metagenome-assembled genomes (MAGs) containing both ARGs and VFs in receiving rivers did not decrease substantially after WWTP-UP, but the abundance of MAGs belonging to pathogenic genera that contain both ARGs and VFs (abbreviated as PAVs) declined markedly. Genome-resolved metagenomics further revealed that WWTP-UP not only reduced most types of VFs and ARGs in PAVs, but also effectively eliminated efflux pump and nutritional VFs carried by PAVs in receiving rivers. WWTP-UP narrowed the pathogenic host ranges of ARGs and VFs and mitigated the cooccurrence of ARGs and VFs in receiving rivers. These findings underline the importance of WWTP-UP for the alleviation of pathogens containing both ARGs and VFs in receiving rivers.
    Keywords antibiotic resistance ; genome ; metagenomics ; ozonation ; transporters ; ultrafiltration ; virulence ; wastewater treatment ; water quality
    Language English
    Dates of publication 2023-07
    Size p. 82.
    Publishing place Higher Education Press
    Document type Article ; Online
    ZDB-ID 2662203-8
    ISSN 2095-221X ; 2095-2201
    ISSN (online) 2095-221X
    ISSN 2095-2201
    DOI 10.1007/s11783-023-1682-4
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Attention Deficit Hyperactivity Disorder Classification Based on Deep Learning.

    Wang, Donglin / Hong, Don / Wu, Qiang

    IEEE/ACM transactions on computational biology and bioinformatics

    2023  Volume 20, Issue 2, Page(s) 1581–1586

    Abstract: Attention Deficit Hyperactivity Disorder (ADHD) is a type of mental health disorder that can be seen from children to adults and affects patients' normal life. Accurate diagnosis of ADHD as early as possible is very important for the treatment of ... ...

    Abstract Attention Deficit Hyperactivity Disorder (ADHD) is a type of mental health disorder that can be seen from children to adults and affects patients' normal life. Accurate diagnosis of ADHD as early as possible is very important for the treatment of patients in clinical applications. Some traditional classification methods, although having been shown powerful in many other classification tasks, are not as successful in the application of ADHD classification. In this paper, we propose two novel deep learning approaches for ADHD classification based on functional magnetic resonance imaging. The first method incorporates independent component analysis with convolutional neural network. It first extracts independent components from each subject. The independent components are then fed into a convolutional neural network as input features to classify the ADHD patient from typical controls. The second method, called the correlation autoencoder method, uses correlations between regions of interest of the brain as the input of an autoencoder to learn latent features, which are then used in the classification task by a new neural network. These two methods use different ways to extract the inter-voxel information from fMRI, but both use convolutional neural networks to further extract predictive features for the classification task. Empirical experiments show that both methods are able to outperform the classical methods such as logistic regression, support vector machines, and other methods used in previous studies.
    MeSH term(s) Adult ; Child ; Humans ; Brain Mapping/methods ; Attention Deficit Disorder with Hyperactivity/diagnostic imaging ; Deep Learning ; Brain/pathology ; Magnetic Resonance Imaging/methods
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1557-9964
    ISSN (online) 1557-9964
    DOI 10.1109/TCBB.2022.3170527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Visual Perception Generalization for Vision-and-Language Navigation via Meta-Learning.

    Wang, Ting / Wu, Zongkai / Wang, Donglin

    IEEE transactions on neural networks and learning systems

    2023  Volume 34, Issue 8, Page(s) 5193–5199

    Abstract: Vision-and-language navigation (VLN) is a challenging task that requires an agent to navigate in real-world environments by understanding natural language instructions and visual information received in real time. Prior works have implemented VLN tasks ... ...

    Abstract Vision-and-language navigation (VLN) is a challenging task that requires an agent to navigate in real-world environments by understanding natural language instructions and visual information received in real time. Prior works have implemented VLN tasks on continuous environments or physical robots, all of which use a fixed-camera configuration due to the limitations of datasets, such as 1.5-m height, 90° horizontal field of view (HFOV), and so on. However, real-life robots with different purposes have multiple camera configurations, and the huge gap in visual information makes it difficult to directly transfer the learned navigation skills between various robots. In this brief, we propose a visual perception generalization strategy based on meta-learning, which enables the agent to fast adapt to a new camera configuration. In the training phase, we first locate the generalization problem to the visual perception module and then compare two meta-learning algorithms for better generalization in seen and unseen environments. One of them uses the model-agnostic meta-learning (MAML) algorithm that requires few-shot adaptation, and the other refers to a metric-based meta-learning method with a feature-wise affine transformation (AT) layer. The experimental results on the VLN-CE dataset demonstrate that our strategy successfully adapts the learned navigation skills to new camera configurations, and the two algorithms show their advantages in seen and unseen environments respectively.
    Language English
    Publishing date 2023-08-04
    Publishing country United States
    Document type Journal Article
    ISSN 2162-2388
    ISSN (online) 2162-2388
    DOI 10.1109/TNNLS.2021.3122579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Is it true that negative emotions cause more utilitarian judgements? from the influence of emotion and cognition.

    Yang, Haibo / Tang, Chunmei / Wang, Donglin

    Cognition & emotion

    2023  Volume 37, Issue 7, Page(s) 1248–1260

    Abstract: ... ...

    Abstract ABSTRACT
    MeSH term(s) Humans ; Judgment ; Cognition ; Emotions ; Morals
    Language English
    Publishing date 2023-11-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639123-0
    ISSN 1464-0600 ; 0269-9931
    ISSN (online) 1464-0600
    ISSN 0269-9931
    DOI 10.1080/02699931.2023.2258572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Images of a Young Welder's Maculopathy.

    Yu, Guangwei / Han, Xinyao / Wang, Donglin

    Ophthalmology

    2023  Volume 130, Issue 12, Page(s) 1348

    MeSH term(s) Humans ; Metal Workers ; Macular Degeneration ; Retinal Diseases/diagnosis ; Retinal Diseases/etiology
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.01.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Coats-like Vasculopathy and Vitreous Hemorrhage in Leber Congenital Amaurosis 6.

    Yu, Guangwei / Niu, Ke / Wang, Donglin

    Ophthalmology. Retina

    2023  Volume 7, Issue 3, Page(s) 281

    MeSH term(s) Humans ; Vitreous Hemorrhage ; Leber Congenital Amaurosis
    Language English
    Publishing date 2023-01-14
    Publishing country United States
    Document type Journal Article
    ISSN 2468-6530
    ISSN (online) 2468-6530
    DOI 10.1016/j.oret.2022.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The association between gray matter volume in the hippocampal subfield and antidepressant efficacy mediated by abnormal dynamic functional connectivity.

    Kuai, Changxiao / Pu, Jiayong / Wang, Donglin / Tan, Zhonglin / Wang, Yan / Xue, Shao-Wei

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 8940

    Abstract: An abnormality of structures and functions in the hippocampus may have a key role in the pathophysiology of major depressive disorder (MDD). However, it is unclear whether structure factors of the hippocampus effectively impact antidepressant responses ... ...

    Abstract An abnormality of structures and functions in the hippocampus may have a key role in the pathophysiology of major depressive disorder (MDD). However, it is unclear whether structure factors of the hippocampus effectively impact antidepressant responses by hippocampal functional activity in MDD patients. We collected longitudinal data from 36 MDD patients before and after a 3-month course of antidepressant pharmacotherapy. Additionally, we obtained baseline data from 43 healthy controls matched for sex and age. Using resting-state functional magnetic resonance imaging (rs-fMRI), we estimated the dynamic functional connectivity (dFC) of the hippocampal subregions using a sliding-window method. The gray matter volume was calculated using voxel-based morphometry (VBM). The results indicated that patients with MDD exhibited significantly lower dFC of the left rostral hippocampus (rHipp.L) with the right precentral gyrus, left superior temporal gyrus and left postcentral gyrus compared to healthy controls at baseline. In MDD patients, the dFC of the rHipp.L with right precentral gyrus at baseline was correlated with both the rHipp.L volume and HAMD remission rate, and also mediated the effects of the rHipp.L volume on antidepressant performance. Our findings suggested that the interaction between hippocampal structure and functional activity might affect antidepressant performance, which provided a novel insight into the hippocampus-related neurobiological mechanism of MDD.
    MeSH term(s) Humans ; Gray Matter/diagnostic imaging ; Depressive Disorder, Major/diagnostic imaging ; Depressive Disorder, Major/drug therapy ; Magnetic Resonance Imaging/methods ; Hippocampus/diagnostic imaging ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Motor Cortex ; Brain
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2024-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56866-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Gut Distribution, Impact Factor, and Action Mechanism of Bacteriocin-Producing Beneficial Microbes as Promising Antimicrobial Agents in Gastrointestinal Infection.

    Peng, Zhen / Wang, Donglin / He, Yuyan / Wei, Ziqi / Xie, Mingyong / Xiong, Tao

    Probiotics and antimicrobial proteins

    2024  

    Abstract: Gastrointestinal (GI) infection by intestinal pathogens poses great threats to human health, and the therapeutic use of antibiotics has reached a bottleneck due to drug resistance. The developments of antimicrobial peptides produced by beneficial ... ...

    Abstract Gastrointestinal (GI) infection by intestinal pathogens poses great threats to human health, and the therapeutic use of antibiotics has reached a bottleneck due to drug resistance. The developments of antimicrobial peptides produced by beneficial bacteria have drawn attention by virtue of effective, safe, and not prone to developing resistance. Though bacteriocin as antimicrobial agent in gut infection has been intensively investigated and reviewed, reviews on that of bacteriocin-producing beneficial microbes are very rare. It is important to explicitly state the prospect of bacteriocin-producing microbes in prevention of gastrointestinal infection towards their application in host. This review discusses the potential of gut as an appropriate resource for mining targeted bacteriocin-producing microbes. Then, host-related factors affecting the bacteriocin production and activity of bacteriocin-producing microbes in the gut are summarized. Accordingly, the multiple mechanisms (direct inhibition and indirect inhibition) behind the preventive effects of bacteriocin-producing microbes on gut infection are discussed. Finally, we propose several targeted strategies for the manipulation of bacteriocin-producing beneficial microbes to improve their performance in antimicrobial outcomes. We anticipate an upcoming emergence of developments and applications of bacteriocin-producing beneficial microbes as antimicrobial agent in gut infection induced by pathogenic bacteria.
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2487792-X
    ISSN 1867-1314 ; 1867-1306
    ISSN (online) 1867-1314
    ISSN 1867-1306
    DOI 10.1007/s12602-024-10222-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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