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Article ; Online: Displays of 18 F-FAPI PET/CT in Myocarditis With Variable Symptom Durations.

Zhou, Weicheng / Sun, Jinju / Wang, Fangyang / Wang, Yi / Chen, Xiao

2023 Volume 48, Issue 9, Page(s) 799–801

Abstract: Abstract: We report cardiac 18 F-FAPI PET/CT findings in 3 cases with myocarditis of varying duration (7 hours, 1 week, and 1 month). Myocarditis with varying symptom durations showed different 18 F-FAPI uptake, suggesting that the 18 F-FAPI PET/CT may ... ...

Abstract	Abstract: We report cardiac 18 F-FAPI PET/CT findings in 3 cases with myocarditis of varying duration (7 hours, 1 week, and 1 month). Myocarditis with varying symptom durations showed different 18 F-FAPI uptake, suggesting that the 18 F-FAPI PET/CT may be helpful in evaluating the extent of fibrosis caused by myocarditis. This information may assist in treatment decision-making for patients with myocarditis.
MeSH term(s)	Humans ; Myocarditis/diagnostic imaging ; Positron Emission Tomography Computed Tomography ; Biological Transport ; Gallium Radioisotopes ; Fluorodeoxyglucose F18
Chemical Substances	Gallium Radioisotopes ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2023-07-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	197628-x
ISSN	1536-0229 ; 0363-9762
ISSN (online)	1536-0229
ISSN	0363-9762
DOI	10.1097/RLU.0000000000004767
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Zs.A 1276: Show issues

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Article ; Online: Mutations in V-ATPase in follicular lymphoma activate autophagic flux creating a targetable dependency.

Wang, Fangyang / Yang, Ying / Klionsky, Daniel J / Malek, Sami N

Autophagy

2022 Volume 19, Issue 2, Page(s) 716–719

Abstract: The recent discovery of recurrent gene mutations in chaperones or components of the vacuolar-type ... ...

Abstract	The recent discovery of recurrent gene mutations in chaperones or components of the vacuolar-type H
MeSH term(s)	Humans ; Autophagy/genetics ; Vacuolar Proton-Translocating ATPases/genetics ; Vacuolar Proton-Translocating ATPases/metabolism ; Lymphoma, Follicular/genetics ; Lymphoma, Follicular/metabolism ; Mutation/genetics ; Vacuoles/metabolism ; Lysosomes/metabolism
Chemical Substances	Vacuolar Proton-Translocating ATPases (EC 3.6.1.-) ; ATP6AP1 protein, human ; VMA21 protein, human (EC 3.6.1.-)
Language	English
Publishing date	2022-05-09
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2454135-7
ISSN	1554-8635 ; 1554-8627
ISSN (online)	1554-8635
ISSN	1554-8627
DOI	10.1080/15548627.2022.2071382
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Article ; Online: Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.

Wang, Fangyang / Yang, Ying / Boudagh, Gabriel / Eskelinen, Eeva-Liisa / Klionsky, Daniel J / Malek, Sami N

Autophagy

2022 Volume 18, Issue 8, Page(s) 1982–2000

Abstract: The discovery of recurrent mutations in subunits and regulators of the vacuolar-type ... ...

Abstract	The discovery of recurrent mutations in subunits and regulators of the vacuolar-type H
MeSH term(s)	Autophagy/genetics ; Humans ; Lymphoma, Follicular/genetics ; Lymphoma, Follicular/metabolism ; Lysosomes/metabolism ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Mutation/genetics ; Vacuolar Proton-Translocating ATPases/genetics ; Vacuolar Proton-Translocating ATPases/metabolism
Chemical Substances	Molecular Chaperones ; VMA21 protein, human (EC 3.6.1.-) ; Vacuolar Proton-Translocating ATPases (EC 3.6.1.-)
Language	English
Publishing date	2022-03-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2454135-7
ISSN	1554-8635 ; 1554-8627
ISSN (online)	1554-8635
ISSN	1554-8627
DOI	10.1080/15548627.2022.2050663
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Article ; Online: Modulation of two-dimensional palladium nanozyme activity to enhance chemodynamic/photothermal combined therapy for melanoma.

Sun, Duo / Liu, Kaijun / Cheng, Yi / Sun, Jinju / Fang, Jingqin / Tang, Yi / Wang, Fangyang / Guo, Yu / Wang, Yi / Chen, Xiao

Journal of materials chemistry. B

2023 Volume 11, Issue 33, Page(s) 7942–7949

Abstract: Nanozymes are artificial enzymes that mimic natural enzyme-like activities and exhibit tremendous potential for tumor chemodynamic therapy. However, the development of novel nanozymes with superior catalytic activities for nanotheranostics remains a ... ...

Abstract	Nanozymes are artificial enzymes that mimic natural enzyme-like activities and exhibit tremendous potential for tumor chemodynamic therapy. However, the development of novel nanozymes with superior catalytic activities for nanotheranostics remains a formidable challenge. Herein, we report a facile synthesis of monodisperse palladium nanosheets (Pd nanosheets) and their assembly on graphene oxide (GO) that enhances the catalytic activities of Pd nanoparticles. Simultaneously, the obtained nanocomposites (rGO-Pd) could be applied as a smart near-infrared (NIR) light-responsive nanotheranostic for near infrared imaging-guided chemodynamic/photothermal combined therapy. Notably, rGO-Pd exhibited high peroxidase mimicking activities, which could catalyze the conversion of intratumoral H
MeSH term(s)	Humans ; Phototherapy/methods ; Palladium/pharmacology ; Reactive Oxygen Species ; Hydrogen Peroxide ; Melanoma ; Tumor Microenvironment
Chemical Substances	graphene oxide ; Palladium (5TWQ1V240M) ; Reactive Oxygen Species ; Hydrogen Peroxide (BBX060AN9V)
Language	English
Publishing date	2023-08-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2702241-9
ISSN	2050-7518 ; 2050-750X
ISSN (online)	2050-7518
ISSN	2050-750X
DOI	10.1039/d3tb01019h
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Article ; Online: Chronic hypoperfusion due to intracranial large artery stenosis is not associated with cerebral β-amyloid deposition and brain atrophy.

Fan, Dongyu / Li, Huiyun / Chen, Dongwan / Chen, Yang / Yi, Xu / Yang, Heng / Shi, Qianqian / Jiao, Fangyang / Tang, Yi / Li, Qiming / Wang, Fangyang / Wang, Shunan / Jin, Rongbing / Zeng, Fan / Wang, Yanjiang

Chinese medical journal

2022 Volume 135, Issue 5, Page(s) 591–597

Abstract: Background: Insufficient cerebral perfusion is suggested to play a role in the development of Alzheimer disease (AD). However, there is a lack of direct evidence indicating whether hypoperfusion causes or aggravates AD pathology. We investigated the ... ...

Abstract	Background: Insufficient cerebral perfusion is suggested to play a role in the development of Alzheimer disease (AD). However, there is a lack of direct evidence indicating whether hypoperfusion causes or aggravates AD pathology. We investigated the effect of chronic cerebral hypoperfusion on AD-related pathology in humans. Methods: We enrolled a group of cognitively normal patients (median age: 64 years) with unilateral chronic cerebral hypoperfusion. Regions of interest with the most pronounced hypoperfusion changes were chosen in the hypoperfused region and were then mirrored in the contralateral hemisphere to create a control region with normal perfusion. 11C-Pittsburgh compound-positron emission tomography standard uptake ratios and brain atrophy indices were calculated from the computed tomography images of each patient. Results: The median age of the 10 participants, consisting of 4 males and 6 females, was 64 years (47-76 years). We found that there were no differences in standard uptake ratios of the cortex (volume of interest [VOI]: P = 0.721, region of interest [ROI]: P = 0.241) and grey/white ratio (VOI: P = 0.333, ROI: P = 0.445) and brain atrophy indices (Bicaudate, Bifrontal, Evans, Cella, Cella media, and Ventricular index, P > 0.05) between the hypoperfused regions and contralateral normally perfused regions in patients with unilateral chronic cerebral hypoperfusion. Conclusion: Our findings suggest that chronic hypoperfusion due to large vessel stenosis may not directly induce cerebral β-amyloid deposition and neurodegeneration in humans.
MeSH term(s)	Aged ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/metabolism ; Arteries ; Atrophy ; Brain/metabolism ; Cerebral Cortex/metabolism ; Cerebrovascular Circulation ; Constriction, Pathologic/pathology ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Positron-Emission Tomography/methods
Chemical Substances	Amyloid beta-Peptides
Language	English
Publishing date	2022-01-04
Publishing country	China
Document type	Journal Article
ZDB-ID	127089-8
ISSN	2542-5641 ; 0366-6999 ; 1002-0187
ISSN (online)	2542-5641
ISSN	0366-6999 ; 1002-0187
DOI	10.1097/CM9.0000000000001918
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Zs.B 1207: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Ua VI Zs.425: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Follicular Lymphoma-associated BTK Mutations are Inactivating Resulting in Augmented AKT Activation.

Hu, Nan / Wang, Fangyang / Sun, Tianyu / Xu, Zhengfan / Zhang, Jing / Bernard, Denzil / Xu, Shilin / Wang, Shaomeng / Kaminski, Mark / Devata, Suma / Phillips, Tycel / Malek, Sami N

Clinical cancer research : an official journal of the American Association for Cancer Research

2021 Volume 27, Issue 8, Page(s) 2301–2313

Abstract: Purpose: On the basis of the recent discovery of mutations in Bruton tyrosine kinase (: Experimental design: We identified novel somatic : Results: We uncovered that all BTK mutants destabilized the BTK protein and some created BTK kinase-dead ... ...

Abstract	Purpose: On the basis of the recent discovery of mutations in Bruton tyrosine kinase ( Experimental design: We identified novel somatic Results: We uncovered that all BTK mutants destabilized the BTK protein and some created BTK kinase-dead mutants. The phospholipase C gamma 2 (PLCγ2) is a substrate of BTK but the BTK mutants did not alter PLCγ2 phosphorylation. Instead, we discovered that BTK mutants induced an exaggerated AKT phosphorylation phenotype in anti-Ig-treated recombinant lymphoma cell lines. The short hairpin RNA-mediated knockdown of BTK expression in primary human nonmalignant lymph node-derived B cells resulted in strong anti-Ig-induced AKT activation, as did the degradation of BTK protein in cell lines using ibrutinib-based proteolysis targeting chimera. Finally, through analyses of primary human follicular lymphoma B cells carrying WT or mutant Conclusions: Altogether, our data uncover novel unexpected properties of follicular lymphoma-associated BTK mutations with direct implications for targeted therapy development in follicular lymphoma.
MeSH term(s)	Agammaglobulinaemia Tyrosine Kinase/genetics ; Agammaglobulinaemia Tyrosine Kinase/metabolism ; Cell Line, Tumor ; Class I Phosphatidylinositol 3-Kinases/antagonists & inhibitors ; Class I Phosphatidylinositol 3-Kinases/metabolism ; DNA Mutational Analysis ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Loss of Function Mutation ; Lymphoma, Follicular/genetics ; Lymphoma, Follicular/pathology ; Mutagenesis, Site-Directed ; Phospholipase C gamma/metabolism ; Phosphorylation/drug effects ; Phosphorylation/genetics ; Primary Cell Culture ; Protein Stability ; Proto-Oncogene Proteins c-akt/metabolism
Chemical Substances	Class I Phosphatidylinositol 3-Kinases (EC 2.7.1.137) ; PIK3CA protein, human (EC 2.7.1.137) ; Agammaglobulinaemia Tyrosine Kinase (EC 2.7.10.2) ; BTK protein, human (EC 2.7.10.2) ; AKT1 protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; PLCG2 protein, human (EC 3.1.4.3) ; Phospholipase C gamma (EC 3.1.4.3)
Language	English
Publishing date	2021-01-08
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1225457-5
ISSN	1557-3265 ; 1078-0432
ISSN (online)	1557-3265
ISSN	1078-0432
DOI	10.1158/1078-0432.CCR-20-3741
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Zs.A 4223: Show issues

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Article ; Online: Synthesis and evaluation of 1-hydroxy/methoxy-4-methyl-2-phenyl-1H-imidazole-5-carboxylic acid derivatives as non-purine xanthine oxidase inhibitors.

Chen, Shaolei / Zhang, Tingjian / Wang, Jian / Wang, Fangyang / Niu, Handong / Wu, Chunfu / Wang, Shaojie

European journal of medicinal chemistry

2015 Volume 103, Page(s) 343–353

Abstract: Xanthine oxidase is a key enzyme that catalyses hypoxanthine and xanthine to uric acid, whose overproduction leads to the gout-causing hyperuricemia. In this study, a series of 1-hydroxy/methoxy-4-methyl-2-phenyl-1H-imidazole-5-carboxylic acid ... ...

Abstract	Xanthine oxidase is a key enzyme that catalyses hypoxanthine and xanthine to uric acid, whose overproduction leads to the gout-causing hyperuricemia. In this study, a series of 1-hydroxy/methoxy-4-methyl-2-phenyl-1H-imidazole-5-carboxylic acid derivatives (4a-4k and 6a-6k) was synthesized and evaluated for their inhibitory potency against xanthine oxidase. The 1-hydroxyl substituted derivatives 4a-4k showed excellent inhibitory potency with IC50 values ranging from 0.003 μM to 1.2 μM, with compounds 4d (IC₅₀ = 0.003 μM), 4e (IC₅₀ = 0.003 μM), and 4f (IC₅₀ = 0.006 μM) manifesting the most potent xanthine oxidase inhibitory potency that were comparable with that of Febuxostat (IC₅₀ = 0.01 μM). Lineweaver-Burk plot analysis revealed that representative compound 4f acted as a mixed-type inhibitor for xanthine oxidase. The basis of significant inhibition of xanthine oxidase by 4f was rationalized by its molecular docking into the active site of xanthine dehydrogenase.
MeSH term(s)	Animals ; Carboxylic Acids/chemistry ; Carboxylic Acids/pharmacology ; Cattle ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Imidazoles/chemical synthesis ; Imidazoles/chemistry ; Imidazoles/pharmacology ; Models, Molecular ; Molecular Structure ; Structure-Activity Relationship ; Xanthine Oxidase/antagonists & inhibitors ; Xanthine Oxidase/metabolism
Chemical Substances	Carboxylic Acids ; Enzyme Inhibitors ; Imidazoles ; imidazole (7GBN705NH1) ; Xanthine Oxidase (EC 1.17.3.2)
Language	English
Publishing date	2015-10-20
Publishing country	France
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	188597-2
ISSN	1768-3254 ; 0009-4374 ; 0223-5234
ISSN (online)	1768-3254
ISSN	0009-4374 ; 0223-5234
DOI	10.1016/j.ejmech.2015.08.056
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Zs.B 784: Show issues

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Article ; Online: PAC-1 and its derivative WF-210 Inhibit Angiogenesis by inhibiting VEGF/VEGFR pathway.

Wang, Fangyang / Wang, Lihui / Li, Yi / Wang, Nannan / Wang, Yating / Cao, Qi / Gong, Ping / Yang, Jingyu / Wu, Chunfu

European journal of pharmacology

2017 Volume 821, Page(s) 29–38

Abstract: Procaspase Activating Compound-1 (PAC-1) and its derivative WF-210 induce apoptosis in cancer cells by activating procaspase-3 to caspase-3. The aim of this study was to extend current knowledge about the mechanisms of PAC-1 and WF-210, particularly ... ...

Abstract	Procaspase Activating Compound-1 (PAC-1) and its derivative WF-210 induce apoptosis in cancer cells by activating procaspase-3 to caspase-3. The aim of this study was to extend current knowledge about the mechanisms of PAC-1 and WF-210, particularly about their effects on tumor angiogenesis. PAC-1 and WF-210 restrained VEGF-induced human umbilical vascular endothelial cells (HUVECs) proliferation, invasion, and tube formation. PAC-1 and WF-210 abrogated VEGF-induced vessel sprouting from rat aortic rings and inhibited vascular formation in the Matrigel plug assay. PAC-1 and WF-210 suppressed phosphorylation of VEGFR2 and its downstream protein kinases c-Src, FAK, and AKT in both HUVECs and U-87 cells. When given to mice bearing subcutaneous or orthotopic xenograft, PAC-1 and WF-210 inhibited the tumor growth and tumor angiogenesis. Further tests showed that PAC-1 and WF-210 inhibited stemness and induced autophagy flux of U-87 cells. This study revealed mechanisms of PAC-1 and WF-210 other than inducing apoptosis, which provides additional support for their using in the clinic.
MeSH term(s)	Angiogenesis Inhibitors/pharmacology ; Animals ; Autophagy/drug effects ; Benzylidene Compounds/pharmacology ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Dioxoles/pharmacology ; Human Umbilical Vein Endothelial Cells ; Humans ; Hydrazines/pharmacology ; Hydrazones/pharmacology ; Male ; Mice ; Neovascularization, Pathologic/drug therapy ; Oxadiazoles/pharmacology ; Phosphorylation/drug effects ; Piperazines/pharmacology ; Rats ; Signal Transduction/drug effects ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor Receptor-2/antagonists & inhibitors ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Xenograft Model Antitumor Assays
Chemical Substances	(4-benzylpiperazin-1-yl)acetic acid (3-allyl-2-hydroxybenzylidene)hydrazine ; Angiogenesis Inhibitors ; Benzylidene Compounds ; Dioxoles ; Hydrazines ; Hydrazones ; Oxadiazoles ; Piperazines ; VEGFA protein, human ; Vascular Endothelial Growth Factor A ; WF-210 compound ; KDR protein, human (EC 2.7.10.1) ; Vascular Endothelial Growth Factor Receptor-2 (EC 2.7.10.1)
Language	English
Publishing date	2017-12-19
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	80121-5
ISSN	1879-0712 ; 0014-2999
ISSN (online)	1879-0712
ISSN	0014-2999
DOI	10.1016/j.ejphar.2017.12.035
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Article ; Online: The roles of conserved aromatic residues (Tyr5 and Tyr42) in interaction of scorpion toxin BmK AGP-SYPU1 with human Na

Meng, Xiangxue / Xu, Yijia / Wang, Fangyang / Zhao, Mingyi / Hou, Xue / Ma, Yuanyuan / Jin, Yao / Liu, Yanfeng / Song, Yongbo / Zhang, Jinghai

International journal of biological macromolecules

2017 Volume 99, Page(s) 105–111

Abstract: Scorpion toxins are invaluable source of therapeutic leads and pharmacological tools which produce influence on the voltage gated sodium channels. In the previous study, our group has reported BmK AGP-SYPU1 (64 amino acids), one scorpion toxin with both ... ...

Abstract	Scorpion toxins are invaluable source of therapeutic leads and pharmacological tools which produce influence on the voltage gated sodium channels. In the previous study, our group has reported BmK AGP-SYPU1 (64 amino acids), one scorpion toxin with both potential α-type and β-type scorpion characteristics and analgesic activity in vivo, act as an activator to hNa
MeSH term(s)	Animals ; CHO Cells ; Conserved Sequence ; Cricetinae ; Cricetulus ; Humans ; Kinetics ; Models, Molecular ; Mutation ; NAV1.7 Voltage-Gated Sodium Channel/metabolism ; Protein Binding ; Protein Domains ; Scorpion Venoms/chemistry ; Scorpion Venoms/genetics ; Scorpion Venoms/metabolism ; Scorpions ; Structure-Activity Relationship ; Tyrosine
Chemical Substances	NAV1.7 Voltage-Gated Sodium Channel ; SCN9A protein, human ; Scorpion Venoms ; Tyrosine (42HK56048U)
Language	English
Publishing date	2017-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2017.01.020
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Article ; Online: Follicular lymphoma-associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR.

Wang, Fangyang / Gatica, Damián / Ying, Zhang Xiao / Peterson, Luke F / Kim, Peter / Bernard, Denzil / Saiya-Cork, Kamlai / Wang, Shaomeng / Kaminski, Mark S / Chang, Alfred E / Phillips, Tycel / Klionsky, Daniel J / Malek, Sami N

The Journal of clinical investigation

2019 Volume 129, Issue 4, Page(s) 1626–1640

Abstract: The discovery of recurrent mutations in subunits of the vacuolar-type H+-translocating ATPase (v-ATPase) in follicular lymphoma (FL) highlights a role for the amino acid- and energy-sensing pathway to mTOR in the pathogenesis of this disease. Here, ... ...

Abstract	The discovery of recurrent mutations in subunits of the vacuolar-type H+-translocating ATPase (v-ATPase) in follicular lymphoma (FL) highlights a role for the amino acid- and energy-sensing pathway to mTOR in the pathogenesis of this disease. Here, through the use of complementary experimental approaches involving mammalian cells and Saccharomyces cerevisiae, we have demonstrated that mutations in the human v-ATPase subunit ATP6V1B2 (also known as Vma2 in yeast) activate autophagic flux and maintain mTOR/TOR in an active state. Engineered lymphoma cell lines and primary FL B cells carrying mutated ATP6V1B2 demonstrated a remarkable ability to survive low leucine concentrations. The treatment of primary FL B cells with inhibitors of autophagy uncovered an addiction for survival for FL B cells harboring ATP6V1B2 mutations. These data support the idea of mutational activation of autophagic flux by recurrent hotspot mutations in ATP6V1B2 as an adaptive mechanism in FL pathogenesis and as a possible new therapeutically targetable pathway.
MeSH term(s)	Autophagic Cell Death ; Cell Line, Tumor ; Cell Survival ; Humans ; Lymphoma, Follicular/enzymology ; Lymphoma, Follicular/genetics ; Lymphoma, Follicular/pathology ; Mutation ; Saccharomyces cerevisiae/enzymology ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Vacuolar Proton-Translocating ATPases/genetics ; Vacuolar Proton-Translocating ATPases/metabolism
Chemical Substances	Saccharomyces cerevisiae Proteins ; MTOR protein, human (EC 2.7.1.1) ; TOR Serine-Threonine Kinases (EC 2.7.1.1) ; VMA2 protein, S cerevisiae (EC 3.6.1.-) ; Vacuolar Proton-Translocating ATPases (EC 3.6.1.-) ; ATP6V1B2 protein, human (EC 7.1.2.2)
Language	English
Publishing date	2019-03-04
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	3067-3
ISSN	1558-8238 ; 0021-9738
ISSN (online)	1558-8238
ISSN	0021-9738
DOI	10.1172/JCI98288
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