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  1. Article ; Online: IDI

    Wang, Fu-Sheng

    Infectious diseases & immunity

    2021  Volume 1, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2021-04-20
    Publishing country China
    Document type Editorial
    ISSN 2693-8839
    ISSN (online) 2693-8839
    DOI 10.1097/ID9.0000000000000004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The corporate path to green innovation: does the digital economy matter?

    Li, Yixiang / Wang, Fusheng

    Environmental science and pollution research international

    2023  Volume 30, Issue 32, Page(s) 79149–79160

    Abstract: As China's digital transformation accelerates, there is growing interest in whether the digital economy can effectively boost green innovation in industrial enterprises and enable China's development to break through the constraints of resources and ... ...

    Abstract As China's digital transformation accelerates, there is growing interest in whether the digital economy can effectively boost green innovation in industrial enterprises and enable China's development to break through the constraints of resources and environment. Therefore, this study analyzes the data of A-share industrial listed enterprises (2011-2020). Results indicate that the digital economy promotes green innovation. The impact of the digital economy on green innovation varies significantly among different types of enterprises, with stronger effects on state-owned enterprises. Digital economy enhances green innovation via boosting public attention and optimizing energy structure. Therefore, playing the role of monitoring public attention, and optimizing energy use are key strategies to promote corporate green innovation.
    MeSH term(s) Industry ; Organizations ; China
    Language English
    Publishing date 2023-06-07
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-27818-0
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    In stock of ZB MED Bonn / Germany

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  3. Article: Study of fatigue damage behavior in off-axis CFRP composites using digital image correlation technology.

    Zhong, Zhendong / Wang, Fusheng / Kong, Fanqi / Chen, Yajun

    Heliyon

    2024  Volume 10, Issue 3, Page(s) e25577

    Abstract: This study investigates the fatigue behavior of off-axis carbon fiber reinforced polymer (CFRP) composites under varying stress levels, with a focus on both tensile-tensile and compressive-compressive loading modes. We conduct a comprehensive analysis of ...

    Abstract This study investigates the fatigue behavior of off-axis carbon fiber reinforced polymer (CFRP) composites under varying stress levels, with a focus on both tensile-tensile and compressive-compressive loading modes. We conduct a comprehensive analysis of energy dissipation and stiffness across various loading conditions, highlighting the critical role of fiber deflection effects in the recovery of tensile-tensile fatigue properties. Utilizing digital image correlation (DIC) technology, we identify both commonalities and distinctions in crack propagation pathways and failure mechanisms between these two fatigue scenarios. In the case of tensile-tensile fatigue, the predominant damage mechanism involves the development of multiple interlaminar shear cracks. These cracks initiate debonding at the fiber/resin interface, propagating from macrocracks at the edges to microcracks at the center, ultimately culminating in fiber pull-out failure. Conversely, in compressive fatigue, damage occurs centrally in the form of intralaminar shear cracks. As damage accumulates, these cracks progressively propagate along the fibers towards the edges, accompanied by localized fiber buckling, ultimately resulting in compressive failure. Furthermore, we determine a critical compressive strain threshold, which serves as a pivotal indicator of failure in compressive-compressive fatigue testing for off-axis CFRP composites.
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e25577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Vitamin B6 ameliorates acute pancreatitis by suppressing the caspase3 signaling pathway.

    Xu, Heling / Yue, Hongqin / Ge, Haijue / Wang, Fusheng

    BMC gastroenterology

    2024  Volume 24, Issue 1, Page(s) 151

    Abstract: Background: Acute pancreatitis (AP) is a prevalent exocrine inflammatory disorder of the pancreas characterized by pancreatic inflammation and injury to acinar cells. Vitamin B6 (VB6) is a vital nutrient that plays a significant role in preserving human ...

    Abstract Background: Acute pancreatitis (AP) is a prevalent exocrine inflammatory disorder of the pancreas characterized by pancreatic inflammation and injury to acinar cells. Vitamin B6 (VB6) is a vital nutrient that plays a significant role in preserving human health and has anti-inflammatory and anti-apoptotic effects.
    Methods: This study aimed to explore the potential pancreatic protective effects of VB6 in mitigating pancreatic inflammation and apoptosis induced by taurocholate sodium (TLCS) in an AP model and to assess the underlying mechanism of action. AP was induced in Sprague‒Dawley (SD) rats through TLCS administration and lipopolysaccharide (LPS)-treated AR42J cells, followed by treatment with VB6.
    Results: Various parameters associated with AP were assessed in both plasma and pancreatic tissues. VB6 has been shown to ameliorate the severity of AP through various mechanisms. It effectively reduces the levels of serum amylase, lipase, and inflammatory factors, thereby mitigating histological injury to the pancreas. Moreover, VB6 inhibited pancreatic apoptosis by downregulating bax expression and up-regulating Bcl2 expression in TLCS-treated rats. Additionally, VB6 suppressed the expression of caspase3. The anti-inflammatory and anti-apoptotic effects of VB6 observed in LPS-treated AR42J cells are consistent with those observed in a rat model of AP.
    Conclusions: These results suggest that VB6 exerts anti-inflammatory and anti-apoptotic effects through inhibition of the caspase3 signaling pathway and has a protective effect against AP.
    MeSH term(s) Animals ; Pancreatitis/drug therapy ; Pancreatitis/metabolism ; Pancreatitis/pathology ; Pancreatitis/chemically induced ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Apoptosis/drug effects ; Taurocholic Acid ; Caspase 3/metabolism ; Rats ; Vitamin B 6/pharmacology ; Vitamin B 6/therapeutic use ; Male ; Lipopolysaccharides ; Amylases/blood ; Pancreas/pathology ; Pancreas/drug effects ; Pancreas/metabolism ; Disease Models, Animal ; Anti-Inflammatory Agents/pharmacology ; Acute Disease ; bcl-2-Associated X Protein/metabolism ; Lipase/metabolism ; Lipase/blood ; Proto-Oncogene Proteins c-bcl-2/metabolism
    Chemical Substances Taurocholic Acid (5E090O0G3Z) ; Caspase 3 (EC 3.4.22.-) ; Vitamin B 6 (8059-24-3) ; Lipopolysaccharides ; Amylases (EC 3.2.1.-) ; Anti-Inflammatory Agents ; bcl-2-Associated X Protein ; Lipase (EC 3.1.1.3) ; Proto-Oncogene Proteins c-bcl-2
    Language English
    Publishing date 2024-05-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041351-8
    ISSN 1471-230X ; 1471-230X
    ISSN (online) 1471-230X
    ISSN 1471-230X
    DOI 10.1186/s12876-024-03248-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Letter: Baseline age on antiviral treatment may significantly influence the clinical response of children with chronic hepatitis B.

    Li, Jing / Wu, Yaxin / Wang, Fu-Sheng

    Alimentary pharmacology & therapeutics

    2024  Volume 59, Issue 3, Page(s) 423–424

    MeSH term(s) Child ; Humans ; Hepatitis B, Chronic/drug therapy ; Antiviral Agents/therapeutic use
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Letter
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.17830
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2206: Show issues Location:
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  6. Article ; Online: Internationalization tactics and enterprise value in the context of the "Belt and Road" initiative-Analysis from the perspective of host country institutional environment and enterprise digital transformation.

    Zhang, Dongchao / Zheng, Xiyue / Wang, Fusheng

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0287324

    Abstract: This paper analyzes the impact of internationalization tactics on the value of 1107 multinational enterprises investing in the "Belt and Road" countries (regions) based on the two dimensions: entry mode and the degree of internationalization (including ... ...

    Abstract This paper analyzes the impact of internationalization tactics on the value of 1107 multinational enterprises investing in the "Belt and Road" countries (regions) based on the two dimensions: entry mode and the degree of internationalization (including the breadth and depth of internationalization). It is found that the choice of sole proprietorship in the "Belt and Road" countries has a positive effect on enterprise value than joint venture. The increase of internationalization breadth and depth can promote enterprise value. Further research shows that the institutional environment of the host country and the digital transformation of enterprises significantly affect the choice of internationalization tactics and enterprise value. Specifically, the better the institutional environment of the host country and the more adequate the digital transformation of enterprises, the more inclined enterprises are to choose the sole proprietorship in the "Belt and Road" countries (regions) to obtain higher enterprise value. A good institutional environment of the host country and the digital transformation of enterprises can positively regulate the relationship between the degree of internationalization and enterprise value. these findings have important for Chinese enterprises to implement internationalization tactics rationally and scientifically, and to continuously improve enterprise value.
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0287324
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  7. Article ; Online: Why is the functional cure rate of young children with chronic hepatitis B receiving antiviral therapy considerably high?

    Wang, Fu-Sheng / Li, Jing / Zhang, Chao

    Hepatology international

    2023  Volume 18, Issue 1, Page(s) 296–298

    MeSH term(s) Child ; Humans ; Child, Preschool ; Hepatitis B, Chronic/drug therapy ; Hepatitis B virus/genetics ; Hepatitis B Surface Antigens ; Antiviral Agents/therapeutic use ; DNA, Viral ; Hepatitis B/drug therapy
    Chemical Substances Hepatitis B Surface Antigens ; Antiviral Agents ; DNA, Viral
    Language English
    Publishing date 2023-10-31
    Publishing country United States
    Document type Letter
    ZDB-ID 2270316-0
    ISSN 1936-0541 ; 1936-0533
    ISSN (online) 1936-0541
    ISSN 1936-0533
    DOI 10.1007/s12072-023-10597-8
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  8. Article ; Online: SwinUNet: a multiscale feature learning approach to cardiovascular magnetic resonance parametric mapping for myocardial tissue characterization.

    Qi, Yifan / Wang, Fusheng / Kong, Jun / Cao, J Jane / Li, Yu Y

    Physiological measurement

    2024  Volume 45, Issue 3

    Abstract: Objective. ...

    Abstract Objective.
    MeSH term(s) Humans ; Predictive Value of Tests ; Heart/diagnostic imaging ; Magnetic Resonance Imaging ; Myocardium/pathology ; Magnetic Resonance Spectroscopy ; Magnetic Resonance Imaging, Cine/methods ; Reproducibility of Results
    Language English
    Publishing date 2024-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1149545-5
    ISSN 1361-6579 ; 0967-3334
    ISSN (online) 1361-6579
    ISSN 0967-3334
    DOI 10.1088/1361-6579/ad2c15
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1559: Show issues Location:
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  9. Article ; Online: Increased platelet-CD8+ T cell aggregates displaying high activation, exhaustion, and tendency to death correlate with disease progression in people with HIV-1.

    Wu, Fengying / Li, Yuanchun / Jiang, Nan / Jiang, Xu / Liu, Xiaoqing / Dai, Xiaopeng / Wang, Fusheng

    Journal of leukocyte biology

    2024  

    Abstract: Platelets engaged in HIV-1 infection by interacting with immune cells, which has been realized broadly. However, the potential interaction between platelets and CD8⁺ T cells remains unidentified. Here, treatment-naïve individuals with HIV-1 (TNs), ... ...

    Abstract Platelets engaged in HIV-1 infection by interacting with immune cells, which has been realized broadly. However, the potential interaction between platelets and CD8⁺ T cells remains unidentified. Here, treatment-naïve individuals with HIV-1 (TNs), complete immunological responders to antiretroviral therapy (CRs), and healthy controls (HCs) were enrolled. Firstly, we found that TNs had low platelet numbers and high CD8⁺ T cell counts when compared with CRs and HCs, leading to low platelet/CD8⁺ T cell ratio in peripheral blood which could effectively differentiate the status of HIV-1 infection. Moreover, cytokines that may be derived from platelets were higher in the plasma of people with HIV-1 despite viral suppression. Furthermore, we demonstrated that platelet-CD8⁺ T cell aggregates were elevated in TNs, which positively correlated with HIV-1 viral load, but negatively correlated with CD4⁺ T cell count and CD4/CD8 ratio. Finally, we revealed that platelet-CD8⁺ T cell aggregates with enhanced activation/exhaustion and pyroptosis/apoptosis than free CD8⁺ T cells. Moreover, platelets-induced caspase-1 activation of CD8⁺ T cells correlated with IL-1β and IL-18 plasma levels. In brief, we revealed the importance of platelets in HIV-1 infection, which might secrete more cytokines, and might mediate CD8⁺ T cell phenotypic characteristics by forming platelet-CD8⁺ T cell aggregates which were related to poor prognosis.
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 605722-6
    ISSN 1938-3673 ; 0741-5400
    ISSN (online) 1938-3673
    ISSN 0741-5400
    DOI 10.1093/jleuko/qiae048
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    Zs.A 603: Show issues Location:
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  10. Article: Integrated transcriptomic and metabolomic analysis reveals the regulation mechanism of early bolting and flowering in two cultivars of

    Zhu, Chenghao / Bai, Yu / Jiang, Yuan / Zhang, Yuanfan / Wang, Shangtao / Wang, Fusheng / Sun, Zhirong

    Heliyon

    2024  Volume 10, Issue 7, Page(s) e28636

    Abstract: ... The root ... ...

    Abstract The root of
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e28636
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