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  1. Article ; Online: Flexible, Reliable, and Lightweight Multiwalled Carbon Nanotube/Polytetrafluoroethylene Membranes with Dual-Nanofibrous Structure for Outstanding EMI Shielding and Multifunctional Applications.

    Shao, Runze / Wang, Guilong / Chai, Jialong / Wang, Guizhen / Zhao, Guoqun

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2308992

    Abstract: In this study, lightweight, flexible, and environmentally robust dual-nanofibrous membranes made of carbon nanotube (CNT) and polytetrafluoroethylene (PTFE) are fabricated using a novel shear-induced in situ fibrillation method for electromagnetic ... ...

    Abstract In this study, lightweight, flexible, and environmentally robust dual-nanofibrous membranes made of carbon nanotube (CNT) and polytetrafluoroethylene (PTFE) are fabricated using a novel shear-induced in situ fibrillation method for electromagnetic interference (EMI) shielding. The unique spiderweb-like network, constructed from fine CNTs and PTFE fibrils, integrates the inherent characteristics of these two materials to achieve high conductivity, superhydrophobicity, and extraordinary chemical resistance. The dual-nanofibrous membranes demonstrate a high EMI shielding effectiveness (SE) of 25.7-42.2 dB at a thickness range of 100-520 µm and the normalized surface-specific SE can reach up to 9931.1 dB·cm
    Language English
    Publishing date 2024-01-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202308992
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Air pollution, EGFR mutation, and cancer initiation.

    Han, Si-Chong / Wang, Gui-Zhen / Zhou, Guang-Biao

    Cell reports. Medicine

    2023  Volume 4, Issue 5, Page(s) 101046

    Abstract: Swanton et al. ...

    Abstract Swanton et al.
    MeSH term(s) Humans ; Particulate Matter/adverse effects ; Air Pollution/adverse effects ; Lung Neoplasms/epidemiology ; Lung Neoplasms/genetics ; ErbB Receptors/genetics ; Mutation
    Chemical Substances Particulate Matter ; ErbB Receptors (EC 2.7.10.1) ; EGFR protein, human (EC 2.7.10.1)
    Language English
    Publishing date 2023-05-18
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2666-3791
    ISSN (online) 2666-3791
    DOI 10.1016/j.xcrm.2023.101046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: 生物信息学和机器学习策略识别骨关节炎炎性衰老生物标志物与临床验证.

    Zhou, Qiao / Liu, Jian / Zhu, Yan / Wang, Yuan / Wang, Guizhen / Qi, Yajun / Hu, Yuedi

    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

    2024  Volume 55, Issue 2, Page(s) 279–289

    Abstract: Objective: To identify inflamm-aging related biomarkers in osteoarthritis (OA).: Methods: Microarray gene profiles of young and aging OA patients were obtained from the Gene Expression Omnibus (GEO) database and aging-related genes (ARGs) were ... ...

    Title translation Identification of Osteoarthritis Inflamm-Aging Biomarkers by Integrating Bioinformatic Analysis and Machine Learning Strategies and the Clinical Validation.
    Abstract Objective: To identify inflamm-aging related biomarkers in osteoarthritis (OA).
    Methods: Microarray gene profiles of young and aging OA patients were obtained from the Gene Expression Omnibus (GEO) database and aging-related genes (ARGs) were obtained from the Human Aging Genome Resource (HAGR) database. The differentially expressed genes of young OA and older OA patients were screened and then intersected with ARGs to obtain the aging-related genes of OA. Enrichment analysis was performed to reveal the potential mechanisms of aging-related markers in OA. Three machine learning methods were used to identify core senescence markers of OA and the receiver operating characteristic (ROC) curve was used to assess their diagnostic performance. Peripheral blood mononuclear cells were collected from clinical OA patients to verify the expression of senescence-associated secretory phenotype (SASP) factors and senescence markers.
    Results: A total of 45 senescence-related markers were obtained, which were mainly involved in the regulation of cellular senescence, the cell cycle, inflammatory response, etc. Through the screening with the three machine learning methods, 5 core senescence biomarkers, including
    Conclusion: FOXO
    MeSH term(s) Humans ; Machine Learning ; Osteoarthritis/genetics ; Osteoarthritis/diagnosis ; Osteoarthritis/metabolism ; Biomarkers/metabolism ; Biomarkers/blood ; Computational Biology/methods ; Aging/genetics ; Inflammation/genetics ; Inflammation/metabolism ; Forkhead Box Protein O3/metabolism ; Forkhead Box Protein O3/genetics ; Cellular Senescence/genetics ; Sirtuin 3/genetics ; Sirtuin 3/metabolism ; Gene Expression Profiling ; Aged ; Male
    Chemical Substances Biomarkers ; Forkhead Box Protein O3 ; Sirtuin 3 (EC 3.5.1.-) ; FOXO3 protein, human ; SIRT3 protein, human (EC 3.5.1.-)
    Language Chinese
    Publishing date 2024-04-19
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2106840-9
    ISSN 1672-173X
    ISSN 1672-173X
    DOI 10.12182/20240360106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mechanistic inference on the roles of oxygenic functional groups that activate peroxymonosulfates in graphene for advanced oxidation.

    Zhou, Xuechun / Wan, Gengping / Zhao, Guoqing / Zhou, Maofan / Wang, Guizhen

    Dalton transactions (Cambridge, England : 2003)

    2022  Volume 51, Issue 45, Page(s) 17416–17429

    Abstract: Developing carbon-based catalysts for advanced oxidation processes, owing to their abundant reserves, metal-free properties, superior biocompatibility as well as great resistance to acids and alkalis, presents an enticing prospect for environmental ... ...

    Abstract Developing carbon-based catalysts for advanced oxidation processes, owing to their abundant reserves, metal-free properties, superior biocompatibility as well as great resistance to acids and alkalis, presents an enticing prospect for environmental remediation. The thermally reduced graphene with diverse surface functional groups from vacuum-promoting thermal expansion of graphene oxide was fabricated by the progressive carbonization from 250 °C to 1000 °C (denoted as G250, G600, and G1000 according to temperature). Among them, G1000 possessed highest defective degrees, the largest specific surface area, and the most abundant, highly active oxygen-containing functional groups such as ketones and quinones. 0.10 g L
    MeSH term(s) Graphite/chemistry ; Oxygen/chemistry ; Peroxides/chemistry ; Oxidation-Reduction
    Chemical Substances peroxymonosulfate (22047-43-4) ; Graphite (7782-42-5) ; Oxygen (S88TT14065) ; Peroxides
    Language English
    Publishing date 2022-11-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d2dt02757g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ni-Carbon Microtube/Polytetrafluoroethylene as Flexible Electrothermal Microwave Absorbers.

    Wu, Lihong / Wang, Guizhen / Shi, Shaohua / Liu, Xiao / Liu, Jun / Zhao, Jinchuan / Wang, Guilong

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2023  Volume 10, Issue 31, Page(s) e2304218

    Abstract: Flexible microwave absorbers with Joule heating performance are urgently desired to meet the demands of extreme service environments. Herein, a type of flexible composite film is constructed by homogeneously dispersing a hierarchical Ni-carbon microtube ( ...

    Abstract Flexible microwave absorbers with Joule heating performance are urgently desired to meet the demands of extreme service environments. Herein, a type of flexible composite film is constructed by homogeneously dispersing a hierarchical Ni-carbon microtube (Ni/CMT) into a processable polytetrafluoroethylene (PTFE) matrix. The Ni/CMT are interconnected into a 3D conductive network, in which the huge interior cavity of the carbon microtube (CMT) improves impedance matching and provides additional hyper channels for electromagnetic (EM) waves dissipation, and the hierarchical magnetic Ni nanoparticles enhance the synergistic interactions between confined heterogeneous interfaces. Such an ingenious structure endows the composites with excellent electrothermal performance and improves their serviceability for application under extreme environments. Moreover, under a low fill loading of 3 wt.%, the Ni/CMT/PTFE (NCP) can achieve excellent low-frequency microwave absorption (MA) property with a minimum reflection loss of -59.12 dB at 5.92 GHz, which covers almost the entire C-band. Relying on their brilliant MA property, an EM sensor is designed and achieved by the resonance coupling of the patterned NCP. This work opens up a new way for the design of next-generation microwave absorbers that meet the requirements of EM packaging, proofing water and removing ice, fire safety, and health monitoring.
    Language English
    Publishing date 2023-09-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202304218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Achieving stable Zn metal anode via a hydrophobic and Zn

    Li, Lianrui / Zhang, Yan / Du, Changlong / Zhou, Xueqing / Xiong, Hualin / Wang, Guizhen / Lu, Xihong

    Journal of colloid and interface science

    2023  Volume 657, Page(s) 644–652

    Abstract: High security and low cost enable aqueous zinc ion batteries (AZIBs) with huge application potential in large-scale energy storage. Nevertheless, the loathsome dendrite and side reactions of Zn anode are harmful to the cycling lifespan of AZIBs. Here, a ... ...

    Abstract High security and low cost enable aqueous zinc ion batteries (AZIBs) with huge application potential in large-scale energy storage. Nevertheless, the loathsome dendrite and side reactions of Zn anode are harmful to the cycling lifespan of AZIBs. Here, a new type of thin amorphous carbon (AC) interface layer (∼100 nm in thickness) is in-situ constructed on the Zn foil (Zn@AC) via a facile low-temperature chemical vapor deposition (LTCVD) method, which owns a hydrophobic peculiarity and a high Zn
    Language English
    Publishing date 2023-12-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2023.11.178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma in vitro and in vivo.

    Guan, Shuzhen / Feng, Lin / Wei, Jinrui / Wang, Guizhen / Wu, Lichuan

    Frontiers of medicine

    2022  Volume 17, Issue 1, Page(s) 132–142

    Abstract: Nasopharyngeal carcinoma (NPC) is a malignant tumor that mainly occurs in East and Southeast Asia. Although patients benefit from the main NPC treatments (e.g., radiotherapy and concurrent chemotherapy), persistent and recurrent diseases still occur in ... ...

    Abstract Nasopharyngeal carcinoma (NPC) is a malignant tumor that mainly occurs in East and Southeast Asia. Although patients benefit from the main NPC treatments (e.g., radiotherapy and concurrent chemotherapy), persistent and recurrent diseases still occur in some NPC patients. Therefore, investigating the pathogenesis of NPC is of great clinical significance. In the present study, replication factor c subunit 4 (RFC4) is a key potential target involved in NPC progression via bioinformatics analysis. Furthermore, the expression and mechanism of RFC4 in NPC were investigated in vitro and in vivo. Our results revealed that RFC4 was more elevated in NPC tumor tissues than in normal tissues. RFC4 knockdown induced G2/M cell cycle arrest and inhibited NPC cell proliferation in vitro and in vivo. Interestingly, HOXA10 was confirmed as a downstream target of RFC4, and the overexpression of HOXA10 attenuated the silencing of RFC4-induced cell proliferation, colony formation inhibition, and cell cycle arrest. For the first time, this study reveals that RFC4 is required for NPC cell proliferation and may play a pivotal role in NPC tumorigenesis.
    MeSH term(s) Humans ; Carcinoma/genetics ; Carcinoma/pathology ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Nasopharyngeal Carcinoma/genetics ; Nasopharyngeal Carcinoma/metabolism ; Nasopharyngeal Carcinoma/pathology ; Nasopharyngeal Neoplasms/genetics ; Nasopharyngeal Neoplasms/metabolism ; Nasopharyngeal Neoplasms/pathology ; Replication Protein C/genetics ; Replication Protein C/metabolism
    Chemical Substances Replication Protein C (EC 3.6.4.-) ; RFC4 protein, human ; HOXA10 protein, human (140441-81-2)
    Language English
    Publishing date 2022-12-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 2617113-2
    ISSN 2095-0225 ; 2095-0217
    ISSN (online) 2095-0225
    ISSN 2095-0217
    DOI 10.1007/s11684-022-0938-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Microwave-Absorbing Foams with Adjustable Absorption Frequency and Structural Coloration.

    Wu, Lihong / Liu, Jun / Liu, Xiao / Mou, Pengpeng / Lv, Haiming / Liu, Rui / Wen, Jianguo / Zhao, Jinchuan / Li, Jianlin / Wang, Guizhen

    Nano letters

    2024  Volume 24, Issue 11, Page(s) 3369–3377

    Abstract: Microwave-absorbing materials with regulatable absorption frequency and optical camouflage hold great significance in intelligent electronic devices and advanced stealth technology. Herein, we present an innovative microwave-absorbing foam that can ... ...

    Abstract Microwave-absorbing materials with regulatable absorption frequency and optical camouflage hold great significance in intelligent electronic devices and advanced stealth technology. Herein, we present an innovative microwave-absorbing foam that can dynamically tune microwave absorption frequencies via a simple mechanical compression while in parallel enabling optical camouflage over broad spectral ranges by adjusting the structural colors. The vivid colors spanning different color categories generated from thin-film interference can be precisely regulated by adjusting the thickness of the conformal TiO
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c05006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Wearable EMI Shielding Composite Films with Integrated Optimization of Electrical Safety, Biosafety and Thermal Safety.

    Li, Liang / Yan, Yongzhu / Liang, Jufu / Zhao, Jinchuan / Lyu, Chaoyi / Zhai, Haoxiang / Wu, Xilong / Wang, Guizhen

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2024  , Page(s) e2400887

    Abstract: Biomaterial-based flexible electromagnetic interference (EMI) shielding composite films are desirable in many applications of wearable electronic devices. However, much research focuses on improving the EMI shielding performance of materials, while ... ...

    Abstract Biomaterial-based flexible electromagnetic interference (EMI) shielding composite films are desirable in many applications of wearable electronic devices. However, much research focuses on improving the EMI shielding performance of materials, while optimizing the comprehensive safety of wearable EMI shielding materials has been neglected. Herein, wearable cellulose nanofiber@boron nitride nanosheet/silver nanowire/bacterial cellulose (CNF@BNNS/AgNW/BC) EMI shielding composite films with sandwich structure are fabricated via a simple sequential vacuum filtration method. For the first time, the electrical safety, biosafety, and thermal safety of EMI shielding materials are optimized integratedly. Since both sides of the sandwich structure contain CNF and BC electrical insulation layers, the CNF@BNNS/AgNW/BC composite films exhibit excellent electrical safety. Furthermore, benefiting from the AgNW conductive networks in the middle layer, the CNF@BNNS/AgNW/BC exhibit excellent EMI shielding effectiveness of 49.95 dB and ultra-fast response Joule heating performance. More importantly, the antibacterial property of AgNW ensures the biosafety of the composite films. Meanwhile, the AgNW and the CNF@BNNS layers synergistically enhance the thermal conductivity of the CNF@BNNS/AgNW/BC composite film, reaching a high value of 8.85 W m
    Language English
    Publishing date 2024-04-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202400887
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  10. Article ; Online: Multi-interfaced Ni/C@RGO/PTFE composites for electromagnetic protection applications with high environmental stability and durability.

    Yuan, Xiang / Li, Liang / Yan, Yongzhu / Wang, Jieping / Zhai, Haoxiang / Wan, Gengping / Liu, Disheng / Liu, Rui / Wang, Guizhen

    Journal of colloid and interface science

    2024  Volume 664, Page(s) 371–380

    Abstract: To efficiently address the growing electromagnetic pollution problem, it is urgently required to research high-performance electromagnetic materials that can effectively absorb or shield electromagnetic waves. In addition, the stability and durability of ...

    Abstract To efficiently address the growing electromagnetic pollution problem, it is urgently required to research high-performance electromagnetic materials that can effectively absorb or shield electromagnetic waves. In addition, the stability and durability of electromagnetic materials in complex practical environments is also an issue that needs to be noticed. Therefore, the starting point for our problem-solving is how to endow magnetic/dielectric multi-interfaced composite materials with excellent electromagnetic protection capability and environmental stability. In this study, magnetic/dielectric multi-interfaced Ni/carbon@reduced graphene oxide/polytetrafluoroethylene (Ni/C@RGO/PTFE) composites were developed to utilize as excellent EWA (electromagnetic wave absorption) and EMI (electromagnetic interference) shielding materials. Due to their diverse heterogeneous interfaces, rich conductive networks, and multiple loss mechanisms, the Ni/C@RGO/PTFE composite exhibits an optimal reflection loss of -61.48 dB and an effective absorption bandwidth of 7.20 GHz, with a filler loading of 5 wt%. Furthermore, Ni/C@RGO/PTFE composite films have an optimal absorption effectiveness value of 9.50 dB and an absorption coefficient of 0.49. Moreover, Ni/C@RGO/PTFE can hold high EWA performance in various corrosive media and maintain more than 90% of EMI shielding effectiveness, which can be attributed to the carbon coating and PTFE matrix acting as dual protective barriers for the susceptible metal Ni, thus obviously improving the stability and durability of composites. Overall, this work presents an effective strategy for the growth of high-performance EWA and EMI shielding materials with outstanding environmental stability and durability, which have wide application prospects in the future.
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2024.03.037
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