LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 36

Search options

  1. Article ; Online: A Mean-Field Game Control for Large-Scale Swarm Formation Flight in Dense Environments.

    Wang, Guofang / Yao, Wang / Zhang, Xiao / Li, Ziming

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 14

    Abstract: As an important part of cyberphysical systems (CPSs), multiple aerial drone systems are widely used in various scenarios, and research scenarios are becoming increasingly complex. However, planning strategies for the formation flying of aerial swarms in ... ...

    Abstract As an important part of cyberphysical systems (CPSs), multiple aerial drone systems are widely used in various scenarios, and research scenarios are becoming increasingly complex. However, planning strategies for the formation flying of aerial swarms in dense environments typically lack the capability of large-scale breakthrough because the amount of communication and computation required for swarm control grows exponentially with scale. To address this deficiency, we present a mean-field game (MFG) control-based method that ensures collision-free trajectory generation for the formation flight of a large-scale swarm. In this paper, two types of differentiable mean-field terms are proposed to quantify the overall similarity distance between large-scale 3-D formations and the potential energy value of dense 3-D obstacles, respectively. We then formulate these two terms into a mean-field game control framework, which minimizes energy cost, formation similarity error, and collision penalty under the dynamical constraints, so as to achieve spatiotemporal planning for the desired trajectory. The classical task of a distributed large-scale aerial swarm system is simulated by numerical examples, and the feasibility and effectiveness of our method are verified and analyzed. The comparison with baseline methods shows the advanced nature of our method.
    MeSH term(s) Computer Communication Networks
    Language English
    Publishing date 2022-07-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22145437
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Carbon-Based Nanomaterials as Drug Delivery Agents for Colorectal Cancer: Clinical Preface to Colorectal Cancer Citing Their Markers and Existing Theranostic Approaches.

    Ma, Jiheng / Wang, Guofang / Ding, Xiaoyu / Wang, Fulin / Zhu, Chunning / Rong, Yunxia

    ACS omega

    2023  Volume 8, Issue 12, Page(s) 10656–10668

    Abstract: Colorectal cancer (CRC) is one of the universally established cancers with a higher incidence rate. Novel progression toward cancer prevention and cancer care among countries in transition should be considered seriously for controlling CRC. Hence, ... ...

    Abstract Colorectal cancer (CRC) is one of the universally established cancers with a higher incidence rate. Novel progression toward cancer prevention and cancer care among countries in transition should be considered seriously for controlling CRC. Hence, several cutting edge technologies are ongoing for high performance cancer therapeutics over the past few decades. Several drug-delivery systems of the nanoregime are relatively new in this arena compared to the previous treatment modes such as chemo- or radiotherapy to mitigate cancer. Based on this background, the epidemiology, pathophysiology, clinical presentation, treatment possibilities, and theragnostic markers for CRC were revealed. Since the use of carbon nanotubes (CNTs) for the management of CRC has been less studied, the present review analyzes the preclinical studies on the application of carbon nanotubes for drug delivery and CRC therapy owing to their inherent properties. It also investigates the toxicity of CNTs on normal cells for safety testing and the clinical use of carbon nanoparticles (CNPs) for tumor localization. To conclude, this review recommends the clinical application of carbon-based nanomaterials further for the management of CRC in diagnosis and as carriers or therapeutic adjuvants.
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c06242
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Effects of five years conservation tillage for hedging against drought, stabilizing maize yield, and improving soil environment in the drylands of northern China.

    Deng, Zizheng / Huang, Mingjing / Zhang, Wuping / Wang, Guofang / Huang, Xuefang / Liang, Gaimei / Li, Nana

    PloS one

    2023  Volume 18, Issue 3, Page(s) e0282359

    Abstract: Continuous tillage cultivation positioning trials can provide the basis for maintaining soil health, improving resource utilization efficiency and crop productivity, and achieving sustainable agricultural development. In this study, changes in soil ... ...

    Abstract Continuous tillage cultivation positioning trials can provide the basis for maintaining soil health, improving resource utilization efficiency and crop productivity, and achieving sustainable agricultural development. In this study, changes in soil stability and water-holding capacity characteristics were measured under different tillage cultivations from a multi-year microscopic perspective and analyzed to evaluate selected key indicators. Continuous monitoring of rainfall utilization efficiency and yield was carried out for five years. Here, we discuss the role of conservation tillage in buffering and stabilizing rainfall precipitation pattern on the fluctuation and uncertainty of soil water retention and water supply capacity and soil quality. The study was carried out on dryland areas of the Loess Plateau in northern China with eight tillage systems established in 2016: no-tillage (NT); no-tillage and straw (NTS); subsoiling (SU); subsoiling and straw (SUS); rotary tillage (RT); rotary tillage and straw (RTS); conventional tillage (CT); and conventional tillage and straw (CTS). All treatments were applied in conjunction with continuous cropping for five years. The evaluated soil parameters were mean weight diameter (MWD), geometric mean diameter (GMD), >0.25 mm aggregate content (R0.25) of water-stable aggregates (WSAs), soil moisture characteristic curve (SMCC), specific soil water capacity (Cθ), soil organic matter (SOM), rainfall utilization efficiency (RUE), and maize yields for five consecutive years. The MWD, GMD, and R0.25 of SUS were 27.38%, 17.57%, and 7.68% more than CTS (control), respectively. Overall, SOM, average annual RUE, and average annual yields increased by 14.64%, 11.89%, and 9.59%, respectively, compared with 2016. Our results strongly suggest that conservation tillage can considerably improve these characterization indicators. SUS was more effective than CTS in the 0-40 cm soil layer at hedging against drought in the area, stabilizing crop production, and achieving sustainable agricultural development.
    MeSH term(s) Soil ; Zea mays ; Droughts ; China ; Water
    Chemical Substances Soil ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0282359
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Machiavellianism and learning-related subjective well-being among Chinese senior high school students: A moderated mediation model.

    Yang, Minqi / Qu, Chunyu / Guo, Hanxiao / Guo, Xicheng / Tian, Kexin / Wang, Guofang

    Frontiers in psychology

    2022  Volume 13, Page(s) 915235

    Abstract: Based on the life history theory and broadening construction theory, the study aimed to investigate the influence of Machiavellianism on the learning-related subjective well-being and the underlying mechanism, 582 Chinese senior high school students (16 ... ...

    Abstract Based on the life history theory and broadening construction theory, the study aimed to investigate the influence of Machiavellianism on the learning-related subjective well-being and the underlying mechanism, 582 Chinese senior high school students (16.8 ± 0.9 years old) including 289 girls (48.3%) and 310 boys were recruited to participate in this study, and they anonymously filled out questionnaires regarding Machiavellianism, learning-related subjective well-being, gratitude, and subjective family economic level. The results showed that: (1) a higher level of Machiavellianism was associated with a lower level of learning-related subjective well-being; (2) gratitude partially mediated the relationship between Machiavellianism and learning-related subjective well-being; (3) subjective family economic level moderated the links between Machiavellianism and learning-related subjective well-being, and between gratitude and learning-related subjective well-being. This study explained how and when Machiavellianism affected Chinese senior high school students' learning-related subjective well-being and provided a deeper understanding of the relationship between Machiavellianism and learning-related subjective well-being.
    Language English
    Publishing date 2022-09-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.915235
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Microplastic Pollution in China, an Invisible Threat Exacerbated by Food Delivery Services

    Liu, Jun / Zhang, Ting / Piché-Choquette, Sarah / Wang, Guofang / Li, Jun

    Bulletin of environmental contamination and toxicology. 2021 Oct., v. 107, no. 4

    2021  

    Abstract: With the rapid development and democratization of the internet and smart phone industry, online food delivery services have become increasingly popular all over the globe, namely in China. One of the unfortunate drawbacks of these delivery services is ... ...

    Abstract With the rapid development and democratization of the internet and smart phone industry, online food delivery services have become increasingly popular all over the globe, namely in China. One of the unfortunate drawbacks of these delivery services is that they mainly use single-use plastics as food packaging, therefore generating large amounts of disposable food containers to meet demand. Such plastic containers reach the end of their service life after a single meal, and are then discarded as plastic waste. The sheer amount of plastic food containers discarded in this manner exacerbates various environmental issues, including one that is invisible to the naked eye: microplastic pollution. This minireview summarizes the history of food delivery services in China, from orders made face-to-face to digital orders, as well as the consequences introduced by the tremendous amounts of plastic waste generated by the food delivery services. Microplastic pollution could be mitigated to a certain extent by improving the classification, handling and management of single-use plastic containers in China. Furthermore, additional studies focusing on microplastic pollution caused by food delivery services are needed, especially as the use of these services is on the rise worldwide.
    Keywords Internet ; durability ; industry ; microplastics ; mobile telephones ; pollution ; toxicology ; wastes ; China
    Language English
    Dates of publication 2021-10
    Size p. 778-785.
    Publishing place Springer US
    Document type Article
    ZDB-ID 6895-0
    ISSN 1432-0800 ; 0007-4861
    ISSN (online) 1432-0800
    ISSN 0007-4861
    DOI 10.1007/s00128-020-03018-1
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  6. Book ; Online ; Thesis: <dc:title>Three problems in geometric analysis related to the study of quasi-local mass</dc:title>

    Körber, Thomas [Verfasser] / Wang, Guofang [Akademischer Betreuer]

    2020  

    Keywords Naturwissenschaften ; Science
    Subject code sg500
    Language English
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    More links

    Kategorien

  7. Article ; Online: Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme.

    Xiao, Yi / Yi, Haomin / Zhu, Jingzhi / Chen, Suhua / Wang, Guofang / Liao, Yilong / Lei, Yuanyuan / Chen, Liyin / Zhang, Xingcai / Ye, Fangfu

    Bioactive materials

    2022  Volume 23, Page(s) 45–52

    Abstract: Toxicity assessment is a major problem in pharmaceutical candidates and industry chemicals development. However, due to the lack of practical analytical methods for DNA adduct analysis, the safety evaluation of drug and industry chemicals was severely ... ...

    Abstract Toxicity assessment is a major problem in pharmaceutical candidates and industry chemicals development. However, due to the lack of practical analytical methods for DNA adduct analysis, the safety evaluation of drug and industry chemicals was severely limited. Here, we develop a DNAzyme-based method to detect DNA adduct damage for toxicity assessment of drugs and chemicals. Among 18 structural variants of G4 DNAzyme, EA2 DNAzyme exhibits an obvious DNA damaging effect of styrene oxide (SO) due to its unstable structure. The covalent binding of SO to DNAzyme disrupts the Hoogsteen hydrogen bonding sites of G-plane guanines and affects the formation of the G4 quadruplex. DNA damage chemicals reduce the peroxidase activity of the G4 DNAzyme to monitor the DNA adduct damage by disrupting the structural integrity of the G4 DNAzyme. Our method for genotoxic assessment of pharmaceutical candidates and industrial chemicals can elucidate the complex chemical pathways leading to toxicity, predict toxic effects of chemicals, and evaluate possible risks to human health.
    Language English
    Publishing date 2022-11-09
    Publishing country China
    Document type Journal Article
    ISSN 2452-199X
    ISSN (online) 2452-199X
    DOI 10.1016/j.bioactmat.2022.10.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Electrochemiluminescence sensor for point-of-care detection of pyrrolizidine alkaloids.

    Xiao, Yi / Yi, Haomin / Wang, Guofang / Chen, Suhua / Li, Xiang / Wu, Qinyu / Zhang, Siyi / Deng, Kexin / He, Yisheng / Yang, Xiaoping

    Talanta

    2022  Volume 249, Page(s) 123645

    Abstract: Pyrrolizidine alkaloids (PAs) and PA N-oxides are hepatotoxic natural products, produced by over 6000 plant species worldwide. However, an unmet need remains for confirmative measurement of PAs in routine clinical tests. Here, we develop a visual, easy- ... ...

    Abstract Pyrrolizidine alkaloids (PAs) and PA N-oxides are hepatotoxic natural products, produced by over 6000 plant species worldwide. However, an unmet need remains for confirmative measurement of PAs in routine clinical tests. Here, we develop a visual, easy-to-use, and economic mesoporous silica-electrochemiluminescence (MPS-ECL) sensor for point-of-care (POC) testing of PAs, utilizing MPS's amplification effect on positive ions. The relationship between PAs' different structures and corresponding Ru(bpy)
    MeSH term(s) Monocrotaline ; Oxides/chemistry ; Point-of-Care Systems ; Pyrrolizidine Alkaloids/chemistry ; Pyrrolizidine Alkaloids/pharmacology
    Chemical Substances Oxides ; Pyrrolizidine Alkaloids ; Monocrotaline (73077K8HYV)
    Language English
    Publishing date 2022-06-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2022.123645
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Simultaneous detection of acetaminophen, catechol and hydroquinone using a graphene-assisted electrochemical sensor

    Wang, Guofang / Zhang, Siyi / Wu, Qinyu / Zhu, Jingzhi / Chen, Suhua / Lei, Yuanyuan / Li, Yanmei / Yi, Haomin / Chen, Liyin / Shi, Zi-Qi / Xiao, Yi

    RSC advances. 2022 Aug. 22, v. 12, no. 37

    2022  

    Abstract: Simple, rapid and sensitive analysis of drug-derived pollutants is critically valuable for environmental monitoring. Here, taking acetaminophen, hydroquinone and catechol as a study example, a sensor based on an ITO/APTES/r-GO@Au electrode was developed ... ...

    Abstract Simple, rapid and sensitive analysis of drug-derived pollutants is critically valuable for environmental monitoring. Here, taking acetaminophen, hydroquinone and catechol as a study example, a sensor based on an ITO/APTES/r-GO@Au electrode was developed for separate and simultaneous determination of phenolic pollutants. ITO electrodes that are modified with 3-aminopropyltriethoxysilane (APTES), graphene (GO) and Au nanoparticles (Au NPs) can significantly enhance the electronic transport of phenolic pollutants at the electrode surface. The redox mechanisms of phenolic pollutants include the electron transfer with the enhancement of r-GO@Au. The modified ITO electrode exhibits excellent electrical properties to phenolic pollutants and a good linear relationship between ECL intensity and the concentration of phenolic pollutants, with a limit of detection of 0.82, 1.41 and 1.95 μM, respectively. The separate and simultaneous determination of AP, CC and HQ is feasible with the ITO/APTES/r-GO@Au electrode. The sensor shows great promise as a low-lost, sensitive, and rapid method for simultaneous determination of drug-derived pollutants.
    Keywords acetaminophen ; catechol ; detection limit ; electrodes ; electron transfer ; graphene ; hydroquinone ; nanogold ; rapid methods ; sensors (equipment)
    Language English
    Dates of publication 2022-0822
    Size p. 23762-23768.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/d2ra03900a
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  10. Article: Electrogenerated chemiluminescence of a Ru(bpy)₃²⁺/arginine system: a specific and sensitive detection of acetaminophen

    Xiao, Yi / Wang, Guofang / Yi, Haomin / Chen, Suhua / Wu, Qinyu / Zhang, Siyi / Deng, Kexin / Zhang, Simeng / Shi, Zi-Qi / Yang, Xiaoping

    RSC advances. 2022 Jan. 24, v. 12, no. 5

    2022  

    Abstract: Ru(bpy)₃Cl₂/TPrA is a prominent and widely used ECL system in analytical science. However, the co-reactant TPrA restricts the variety of applications because of its toxicity, volatility, and high cost. Here, we use arginine (Arg) as an alternative co- ... ...

    Abstract Ru(bpy)₃Cl₂/TPrA is a prominent and widely used ECL system in analytical science. However, the co-reactant TPrA restricts the variety of applications because of its toxicity, volatility, and high cost. Here, we use arginine (Arg) as an alternative co-reactant for Ru(bpy)₃²⁺ by taking advantage of its low cost, non-toxicity, and biocompatibility. The mechanism of the Ru(bpy)₃²⁺/Arg system is that the deprotonated Arg can react with Ru(bpy)₃²⁺ to release emission. The similarity between the Ru(bpy)₃²⁺/Arg, Ru(bpy)₃²⁺/TPrA, and Ru(bpy)₃²⁺/DBAE systems demonstrates that Arg can be used as an alternative co-reactant for Ru(bpy)₃²⁺ ECL. As a proof of concept, we achieve an excellent performance for acetaminophen (Ace) detection based on the specificity of Arg and Ace, with excellent linearity, low detection limits, and good recoveries. This work is promising to expand the scope of the Ru(bpy)₃²⁺/Arg system and move forward their applications in bioassays.
    Keywords acetaminophen ; arginine ; biocompatibility ; electrochemiluminescence ; toxicity
    Language English
    Dates of publication 2022-0124
    Size p. 3157-3164.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/d1ra09371a
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

To top