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  1. Book ; Online ; E-Book: Epigenetics in aquaculture

    Piferrer, Francesc / Wang, Han-Ping

    2023  

    Author's details edited by Francesc Piferrer, Han-Ping Wang
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (486 Seiten)
    Publisher John Wiley
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030340928
    ISBN 978-1-119-82192-2 ; 9781119821915 ; 1-119-82192-4 ; 1119821916
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Sex control in aquaculture

    Wang, Han-Ping / Piferrer, Francesc / Chen, Songlin

    2019  

    Author's details edited by Han-Ping Wang, Francesc Piferrer, Song-Lin Chen
    Keywords Aquaculture ; Fishes/Reproduction
    Subject code 639.8
    Language English
    Size 2 Bände in 1 Online-Ressource (861 Seiten)
    Publisher Wiley Blackwell
    Publishing place Hoboken, NJ ; Chichester
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019879408
    ISBN 9781119127284 ; 9781119127277 ; 9781119127260 ; 1119127289 ; 1119127270 ; 1119127262
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Roles of vesicular monoamine transporter 2 in neuronal development and histaminergic signalling-Insights from zebrafish.

    Wang, Han

    Acta physiologica (Oxford, England)

    2021  Volume 234, Issue 1, Page(s) e13739

    MeSH term(s) Animals ; Neurogenesis ; Neuropeptides ; Vesicular Monoamine Transport Proteins ; Zebrafish
    Chemical Substances Neuropeptides ; Vesicular Monoamine Transport Proteins
    Language English
    Publishing date 2021-11-09
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2218636-0
    ISSN 1748-1716 ; 1748-1708
    ISSN (online) 1748-1716
    ISSN 1748-1708
    DOI 10.1111/apha.13739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs 229: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Introduction to the Special Issue: Microbiome and its impact on immunity in fish and shrimp.

    Wang, Han-Ching / Lu, Hsiao-Pei

    Fish & shellfish immunology

    2024  Volume 148, Page(s) 109501

    MeSH term(s) Animals ; Fishes ; Microbiota ; Crustacea ; Seafood ; Penaeidae
    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Editorial
    ZDB-ID 1067738-0
    ISSN 1095-9947 ; 1050-4648
    ISSN (online) 1095-9947
    ISSN 1050-4648
    DOI 10.1016/j.fsi.2024.109501
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    In stock of ZB MED Bonn / Germany

    Z 5917: Show issues

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  5. Book ; Online: Therapeutic Implications of Circadian Rhythms

    Zhang, Erquan / Wang, Han / Yang, Guangrui

    2015  

    Abstract: Circadian rhythms are biological processes displaying endogenous and entrainable oscillations of about 24 hours. They are driven by a group of genes called clock genes that have been widely observed in plants, animals and even in bacteria. In mammals, ... ...

    Abstract Circadian rhythms are biological processes displaying endogenous and entrainable oscillations of about 24 hours. They are driven by a group of genes called clock genes that have been widely observed in plants, animals and even in bacteria. In mammals, the core clock genes are rhythmically expressed in both the suprachiasmatic nucleus (SCN), the master clock residing in the hypothalamus, and almost all peripheral tissues where they control numerous target genes in a circadian manner, and thus affect many physiological and biochemical processes. Evidence suggests that disruption of the circadian rhythms (or desynchronization) is a significant risk factor for the development of metabolic diseases, cardiovascular diseases, cancer and sleep disorders. Evidence also suggests that the disruption suppresses immune function and increases vulnerability to infectious diseases. Restoring or strengthening the circadian rhythm may be therapeutic for these conditions.-

    This becomes exceptionally important in modern societies because many people are suffering from frequent desynchronization due to shift working, exposure to artificial light, travel by transmeridian air flight, and involvement in social activities. Besides, the temporal variations in the incidence and severity of many diseases, such as the onset of cardiovascular events, chronic obstructive pulmonary disease (COPD), inflammatory diseases and mental disorders have also drawn increasing attention to the circadian clock. The circadian rhythms affect not only the health status, but also the drug efficiency. The effects (and side effects) of many drugs vary with biological timing. The tolerance of many medications displays circadian variation as well. The timing of medical treatment in coordination with the body clock may significantly increase the desired effects of drugs, and lower the dose and toxicity.-

    In addition, circadian rhythms can also be modulated by some therapeutic drugs, for example, melatonin and modafinil, which are used to treat circadian rhythm sleep disorders. In this Research Topic, we assemble a series of critical review and research articles that focus on the therapeutic implications of circadian rhythms. Topics include, but are not limited to: • Circadian disruption caused diseases or disorders and related intervention • Temporal manifestation of diseases or disorders and therapeutic implications • The effects of circadian rhythms on drugs • The effects of drugs on circadian rhythms
    Keywords Science (General) ; Therapeutics. Pharmacology
    Size 1 electronic resource (96 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020091852
    ISBN 9782889196654 ; 2889196658
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Reprogramming the Circadian Dynamics of Epileptic Genes in Mouse Temporal Lobe Epilepsy.

    Sun, Sha / Wang, Han

    International journal of molecular sciences

    2023  Volume 24, Issue 7

    Abstract: Temporal lobe epilepsy (TLE) is a common and severe epilepsy displaying rhythmicity in humans and animals. However, how the circadian clock contributes to TLE remains elusive. A recent circadian analysis of the ventral hippocampal transcriptome of ... ...

    Abstract Temporal lobe epilepsy (TLE) is a common and severe epilepsy displaying rhythmicity in humans and animals. However, how the circadian clock contributes to TLE remains elusive. A recent circadian analysis of the ventral hippocampal transcriptome of pilocarpine-induced TLE mice revealed as many as 1650 rhythmically expressed transcripts. Here, a comparison of the mouse ventral hippocampal transcriptome with the human epilepsy-related gene set identified 315 possible mouse epilepsy-related genes. Rhythmicity analysis classified them into arrhythmicity, loss-of-rhythmicity, gain-of-rhythmicity, and rhythmicity-maintaining groups. KEGG and GO analyses of these mouse epilepsy genes suggest their involvement in circadian entrainment. In TLE mice,
    MeSH term(s) Mice ; Humans ; Animals ; Epilepsy, Temporal Lobe/chemically induced ; Epilepsy, Temporal Lobe/genetics ; Epilepsy, Temporal Lobe/metabolism ; Epilepsy/metabolism ; Pilocarpine/toxicity ; Hippocampus/metabolism ; Up-Regulation
    Chemical Substances Pilocarpine (01MI4Q9DI3)
    Language English
    Publishing date 2023-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24076400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Degraded tactile coding in the Cntnap2 mouse model of autism.

    Wang, Han Chin / Feldman, Daniel E

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Atypical sensory processing in autism involves altered neural circuit function and neural coding in sensory cortex, but the nature of coding disruption is poorly understood. We characterized neural coding in L2/3 of whisker somatosensory cortex (S1) ... ...

    Abstract Atypical sensory processing in autism involves altered neural circuit function and neural coding in sensory cortex, but the nature of coding disruption is poorly understood. We characterized neural coding in L2/3 of whisker somatosensory cortex (S1) of
    Language English
    Publishing date 2023-09-30
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.09.29.560240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Study on Water Resource Carrying Capacity of Zhengzhou City Based on DPSIR Model.

    Jia, Yizhen / Wang, Han

    International journal of environmental research and public health

    2023  Volume 20, Issue 2

    Abstract: Based on the driving force-pressure-state-impact-response (DPSIR) model, a comprehensive evaluation index system is constructed. The index weight is determined by the combination weighting method in combination with the data of 2010-2019. The TOPSIS ... ...

    Abstract Based on the driving force-pressure-state-impact-response (DPSIR) model, a comprehensive evaluation index system is constructed. The index weight is determined by the combination weighting method in combination with the data of 2010-2019. The TOPSIS model is used to comprehensively analyze the water resource carrying capacity of Zhengzhou as the central city in China with a developed economy and relatively short water resources. The study results are as follows. (1) During the sample period, the comprehensive evaluation value of water resources carrying capacity of Zhengzhou increases from 0.4183 in 2010 to 0.5560 in 2019, with an overall fluctuating rise. Simultaneously, the water resource carrying capacity grade improves from Grade III (normal carrying capacity) to Grade II (good carrying capacity). (2) The contribution of each subsystem to the comprehensive evaluation value increases year by year. Among them, S subsystem and I subsystem make the largest contribution to the comprehensive carrying capacity. R subsystem makes a relatively stable contribution to the overall carrying capacity. Affected by GDP growth rate and uneven temporal-spatial distribution of water resources in Zhengzhou, the D subsystem and P subsystem of water resource carrying capacities show the fluctuating change. Finally, based on the above conclusions, this paper puts forward the countermeasures and suggestions to improve the level of water resource carrying capacity of Zhengzhou.
    MeSH term(s) Conservation of Natural Resources/methods ; Water Resources ; Cities ; Urbanization ; China
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20021394
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  9. Article ; Online: Introduction to the Special Issue: The possibility of immune priming or even memory in invertebrate species.

    Wang, Han-Ching / Ng, Tze Hann

    Developmental and comparative immunology

    2023  Volume 148, Page(s) 104919

    MeSH term(s) Animals ; Invertebrates ; Immunity, Innate
    Language English
    Publishing date 2023-08-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 752411-0
    ISSN 1879-0089 ; 0145-305X
    ISSN (online) 1879-0089
    ISSN 0145-305X
    DOI 10.1016/j.dci.2023.104919
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1327: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: Solitary hypovascular hepatic nodules: comparison and differentiation between peripheral nodular cholangiocarcinoma and atypical liver hemangioma with MRI.

    Wang, Han / Guo, Shengren

    Translational cancer research

    2023  Volume 12, Issue 9, Page(s) 2308–2318

    Abstract: Background: Peripheral nodular cholangiocarcinoma (PCC) and hepatic hemangioma (HG) significantly differ in treatment strategies and prognosis. However, they can present similar imaging characteristics, making them difficult to distinguish. The ... ...

    Abstract Background: Peripheral nodular cholangiocarcinoma (PCC) and hepatic hemangioma (HG) significantly differ in treatment strategies and prognosis. However, they can present similar imaging characteristics, making them difficult to distinguish. The distinction between PCC and atypical HG using pre-operative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) holds substantial significance.
    Methods: Fifty-four cases of solitary hypovascular hepatic nodules (nodules ≤3 cm in diameter and enhancement not exceeding the hepatic parenchyma) confirmed pathologically were collected, including 25 cases of PCC and 29 cases of HG. The clinical and DCE-MRI features were observed, and the apparent diffusion coefficient (ADC) values were compared. The
    Results: The signal of PCC was more heterogeneous and could be shown as a ring hyperintensity signal on diffusion weighted imaging (DWI). The T2-weighted imaging (T2WI) signal of HG lesions showed a more homogeneous high-intense signal. The ADC value of PCC patients was lower than that of HG patients. Most of the patients in the two groups presented marginal enhancement in the arterial phase with infrequent abnormal perfusion around. The intratumoral vascular traversal signs in the PCC group showed a diagnostic significance. Among the lesions with marginal enhancement at arterial stage, the enhancement in PCC group was more likely to have annular enhancement with the main manifestation of delay reduction and nebulous or separated/astral center. On the other hand, HG tended to be more likely to have nodular enhancement in the arterial phase with delayed invariance at the margins and with no significant enhancement at the center. The area under the curves (AUC) of the three radiologists before and after the two readings were 0.645 and 0.888, respectively.
    Conclusions: In the differentiation of PCC and atypical liver hemangioma, the presence of a circular hyper-intense signal in DWI, the ADC values, and the pattern and extent of enhancement of marginal and central lesions were of diagnostic significance.
    Language English
    Publishing date 2023-08-25
    Publishing country China
    Document type Journal Article
    ZDB-ID 2901601-0
    ISSN 2219-6803 ; 2218-676X
    ISSN (online) 2219-6803
    ISSN 2218-676X
    DOI 10.21037/tcr-23-27
    Database MEDical Literature Analysis and Retrieval System OnLINE

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