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  1. Book ; Thesis: SB-431542 inhibition of TGF-β signaling inhibits bone regeneration in rat calvaria bone defects

    Wang, Heng

    2020  

    Author's details vorgelegt von Heng Wang
    Language English
    Size 69 Seiten, Illustrationen, Diagramme, 21 cm
    Publishing place Frankfurt am Main
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Johann Wolfgang Goethe-Universität Frankfurt am Main, 2021
    HBZ-ID HT021282554
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 D 72 order for loan Magazin

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  2. Article ; Online: Gender and Sexuality Disparities in Perception, Attitude and Social Intimacy Among Sinophone Youth Toward Transgender and Gender Non-Conforming Individuals: Based on an Internet Survey.

    Hu, Xiyuan / Wang, Heng

    Journal of homosexuality

    2024  , Page(s) 1–22

    Abstract: The study aims at assessing gender and sexuality characteristics (GSC) in perception, attitude, and social intimacy among Sinophone youth toward transgender and gender non-conforming (TGNC) people. Based on an internet survey with 3 825 valid ... ...

    Abstract The study aims at assessing gender and sexuality characteristics (GSC) in perception, attitude, and social intimacy among Sinophone youth toward transgender and gender non-conforming (TGNC) people. Based on an internet survey with 3 825 valid questionnaires, we distinguished the general public into TGNC, cisgender heterosexual, and cisgender non-heterosexual individuals. Then we classified TGNC individuals into trans females, trans males, and non-binary/genderqueer people and cisgender individuals into cisgender females and cisgender males. The chi-square test, one-way analysis of variance (ANOVA), and multiple linear regression were used. We found that the evident gender and sexuality disparities in perception, attitude, and social intimacy toward TGNC individuals exist both in and out of TGNC individuals. Negative perceptions and attitudes as well as alienated social intimacy were most pronounced among cisgender heterosexual people (Chi-square test, one-way ANOVA, and multiple linear regression: all
    Language English
    Publishing date 2024-01-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193138-6
    ISSN 1540-3602 ; 0091-8369
    ISSN (online) 1540-3602
    ISSN 0091-8369
    DOI 10.1080/00918369.2023.2287031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1141: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Dragonfly visual evolutionary neural network: A novel bionic optimizer with related LSGO and engineering design optimization.

    Wang, Heng / Zhang, Zhuhong

    iScience

    2024  Volume 27, Issue 3, Page(s) 109040

    Abstract: Biological visual systems intrinsically include multiple kinds of motion-sensitive neurons. Some of them have been successfully used to construct neural computational models for problem-specific engineering applications such as motion detection, object ... ...

    Abstract Biological visual systems intrinsically include multiple kinds of motion-sensitive neurons. Some of them have been successfully used to construct neural computational models for problem-specific engineering applications such as motion detection, object tracking, etc. Nevertheless, it remains unclear how these neurons' response mechanisms can be contributed to the topic of optimization. Hereby, the dragonfly's visual response mechanism is integrated with the inspiration of swarm evolution to develop a dragonfly visual evolutionary neural network for large-scale global optimization (LSGO) problems. Therein, a grayscale image input-based dragonfly visual neural network online outputs multiple global learning rates, and later, such learning rates guide a population evolution-like state update strategy to seek the global optimum. The comparative experiments show that the neural network is a competitive optimizer capable of effectively solving LSGO benchmark suites with 2000 dimensions per example and the design of an operational amplifier.
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2024.109040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cell migration: Collective cell migration is intrinsically stressful.

    Wang, Heng / Chen, Jiong

    Current biology : CB

    2024  Volume 34, Issue 7, Page(s) R275–R278

    Abstract: Collective cell migration is a key cellular process in development and disease. A new study reports that ER stress is induced during collective cell migration and an intrinsic mechanism prevents migratory cells from over-reacting to ER stress. ...

    Abstract Collective cell migration is a key cellular process in development and disease. A new study reports that ER stress is induced during collective cell migration and an intrinsic mechanism prevents migratory cells from over-reacting to ER stress.
    MeSH term(s) Cell Movement
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2024.02.061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Association between lipoprotein(a) and insulin resistance in Chinese adults: results from the China health and nutrition survey.

    Wang, Heng / Fan, Jia-Li

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1234140

    Abstract: Background: Lipoprotein(a) [Lp(a)] is a well-established risk factor for cardiovascular diseases. However, the relationship between Lp(a) and insulin resistance (IR) remains controversial. The aim of the current study was to investigate the association ... ...

    Abstract Background: Lipoprotein(a) [Lp(a)] is a well-established risk factor for cardiovascular diseases. However, the relationship between Lp(a) and insulin resistance (IR) remains controversial. The aim of the current study was to investigate the association between Lp(a) concentrations and IR in Chinese adults.
    Methods: Cross-sectional study of 1908 cases and 5725 controls was performed for identifying the association of Lp(a) with IR. IR was assessed using the triglyceride glucose (TyG) index, and patients with a TyG index greater than the third quartile were defined as having IR.
    Results: The distribution of Lp(a) in Chinese adults was skewed, with a median of 7.90mg/dL. Lp(a) concentrations were significantly and progressively lower with increasing TyG index values in Chinese adult males, but not in females. Multiple regression analysis adjusted for a wide range of risk factors showed that Lp(a) concentrations were inversely and independently associated with IR in Chinese adult males, but not in females. The suggested Lp (a) cutoff for discriminating IR from non-IR was 4.7 mg/dL in Chinese adult males. Lp(a) interacts with gender in IR on both additive and multiplicative scale in Chinese adults.
    Conclusion: Lp(a) concentrations inversely associated with IR in Chinses adult males, but the association in women needs further study. In Chinese adults, Lp(a) interacts with gender in IR.
    MeSH term(s) Male ; Humans ; Adult ; Female ; Insulin Resistance ; Lipoprotein(a) ; Cross-Sectional Studies ; East Asian People ; Nutrition Surveys
    Chemical Substances Lipoprotein(a)
    Language English
    Publishing date 2023-10-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1234140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Effect of integrated perioperative rehabilitation intervention under the fast-track surgery concept on stress and complications in patients undergoing craniocerebral injury surgery.

    Zhao, Bin / Wang, Heng

    Frontiers in surgery

    2023  Volume 9, Page(s) 1014211

    Abstract: Objective: To observe the intervention effect of perioperative rehabilitation intervention of integrated medical care the concept of FTS on stress response and postoperative complications in patients undergoing craniocerebral injury surgery.: Methods!# ...

    Abstract Objective: To observe the intervention effect of perioperative rehabilitation intervention of integrated medical care the concept of FTS on stress response and postoperative complications in patients undergoing craniocerebral injury surgery.
    Methods: 70 patients with Traumatic brain injury (TBI) admitted to the Department of Neurosurgery of our Hospital from January 2019 to December 2021 were as the research objects and were divided into general group and FTS group according to the random number table method, with 35 cases in each group. The general group was intervened with perioperative basic nursing measures for TBI, and the FTS group was intervened with perioperative rehabilitation model of integrated medical care under the concept of FTS on the basis of the general group. The two groups of patients were compared in hemodynamic indexes (heart rate, mean arterial pressure), stress hormone levels (CORT, GLU, E), changes in motor neurological function (GCS score, NHISS score, FMA score), occurrence of postoperative complications (infection, pressure sores, rebleeding, central hyperthermia), short-term quality of life (SF-36) before and after the intervention.
    Results: After intervention, the levels of HR, MAP, COR, GLU, and E were significantly lower in FTS group than in the general group (all
    Conclusion: The implementation of integrated perioperative rehabilitation interventions under the concept of FTS for patients with TBI can significantly alleviate patients' stress, promote recovery, reduce the incidence of complications, and improve short-term quality of life, which is worthy of clinical promotion.
    Language English
    Publishing date 2023-01-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2022.1014211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Plasma drug concentration resulting from body surface area-based dosage.

    Wang, Heng / Xue, Song

    Indian journal of pharmacology

    2023  Volume 55, Issue 5, Page(s) 340

    MeSH term(s) Humans ; Body Surface Area ; Body Weight
    Language English
    Publishing date 2023-11-06
    Publishing country India
    Document type Letter
    ZDB-ID 605829-2
    ISSN 1998-3751 ; 0253-7613
    ISSN (online) 1998-3751
    ISSN 0253-7613
    DOI 10.4103/ijp.ijp_470_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1983: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 311: Show issues

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  8. Article ; Online: Simultaneous speciation analysis of arsenic and iodine in human urine by high performance liquid chromatography-inductively coupled plasma mass spectrometry.

    Zhou, Shaomin / Wang, Heng / Tang, Jun / Wang, Heng / Yan, Jianbo

    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

    2023  Volume 40, Issue 3, Page(s) 555–562

    Abstract: A high-performance liquid chromatography-inductively coupled plasma mass spectrometry-based method was developed for the simultaneous determination of four iodine species (i.e. iodate, 3-iodo-tyrosine, 3,5-diiodo-tyrosine, and iodide) and six arsenic ... ...

    Abstract A high-performance liquid chromatography-inductively coupled plasma mass spectrometry-based method was developed for the simultaneous determination of four iodine species (i.e. iodate, 3-iodo-tyrosine, 3,5-diiodo-tyrosine, and iodide) and six arsenic species (i.e. arsenobetaine, arsenite, dimethylarsinic acid, arsenocholine, methylarsonic acid, and arsenate) in human urine. The chromatographic separation was performed on a Dionex IonPac As7 anion exchange column. The mobile phase was initiated with 0.5 mmol/L ammonium carbonate solution, followed by 50 mmol/L ammonium carbonate/100 mmol/L ammonium nitrate solution (with 4% methanol). The limits of quantification of the analytes ranged from 0.045 to 2.26 μg/L. At three spiked levels (10.0, 20.0, 50.0 μg/L), the average recoveries (%) ranged from 87.4 to 113.1%, and the relative standard deviations (RSD, %) ranged from 0.4 to 17.2%. The ratio of the sum of six arsenic species to the total arsenic measured by ICPMS ranged from 77.4 to 121.2%, and the ratio of the sum of the four iodine species to the total iodine ranged from 70.7 to 114.7%, indicating a good agreement between these two methods for both arsenic and iodine.
    MeSH term(s) Humans ; Arsenic/analysis ; Chromatography, High Pressure Liquid/methods ; Mass Spectrometry/methods ; Iodine ; Tyrosine ; Carbonates
    Chemical Substances Arsenic (N712M78A8G) ; ammonium carbonate (NJ5VT0FKLJ) ; Iodine (9679TC07X4) ; Tyrosine (42HK56048U) ; Carbonates
    Language English
    Publishing date 2023-12-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1483376-1
    ISSN 1348-2246 ; 1348-2246
    ISSN (online) 1348-2246
    ISSN 1348-2246
    DOI 10.1007/s44211-023-00472-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effects of square dance exercise on cognitive function in elderly individuals with mild cognitive impairment: the mediating role of balance ability and executive function.

    Wang, Heng / Pei, Zhengguo / Liu, Yangyang

    BMC geriatrics

    2024  Volume 24, Issue 1, Page(s) 156

    Abstract: Background: Square dancing is a kind of aerobic fitness exercise without environmental restrictions that yields many benefits for physical and mental health; this exercise is popular among middle-aged and elderly people in China and in these populations ...

    Abstract Background: Square dancing is a kind of aerobic fitness exercise without environmental restrictions that yields many benefits for physical and mental health; this exercise is popular among middle-aged and elderly people in China and in these populations in other countries. This study aimed to evaluate the effects of square dance exercise on the overall cognitive function of elderly individuals with mild cognitive impairment (MCI) and to research its mechanisms.
    Methods: A total of 60 elderly people with MCI (60-69 years old) without square dance experience were selected and randomly divided into an experimental group (n = 30) and a control group (n = 30). The experimental group participated in square dance exercise for 12 weeks, while the control group maintained their original lifestyle habits. One week before and after the intervention period, the overall cognitive function, physical fitness, and executive function of both groups were measured.
    Results: According to the results, square dance exercise directly improved the overall cognitive function of elderly individuals with MCI and indirectly affected overall cognitive function through the mediating effects of balance ability and executive function.
    Conclusions: Square dance exercise represents a nonpharmacological intervention for the prevention and treatment of MCI. Importantly, it is best to combine this exercise with other forms of physical exercise and comprehensive treatment programs such as cognitive training, social interaction, and psychological intervention to realize its maximum effect.
    MeSH term(s) Aged ; Humans ; Middle Aged ; Dancing ; Executive Function ; Cognition ; Exercise ; Cognitive Dysfunction/therapy ; Cognitive Dysfunction/psychology
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-024-04714-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Impact of intraoperative hypothermia on the recovery period of anesthesia in elderly patients undergoing abdominal surgery.

    Yin, Lu / Wang, Heng / Yin, Xiaorong / Hu, Xiuying

    BMC anesthesiology

    2024  Volume 24, Issue 1, Page(s) 124

    Abstract: Background: This study aimed to investigate the impact of intraoperative hypothermia on the recovery period of anesthesia in elderly patients undergoing abdominal surgery.: Methods: A prospective observational study was conducted based on inclusion ... ...

    Abstract Background: This study aimed to investigate the impact of intraoperative hypothermia on the recovery period of anesthesia in elderly patients undergoing abdominal surgery.
    Methods: A prospective observational study was conducted based on inclusion and exclusion criteria. A total of 384 elderly patients undergoing abdominal surgery under general anesthesia were enrolled in a grade A tertiary hospital in Chengdu, Sichuan Province from October 2021 and October 2022. After anesthesia induction, inflatable warming blankets were routinely used for active heat preservation, and nasopharyngeal temperature was monitored to observe the occurrence of intraoperative hypothermia. Patients were divided into hypothermia group and nonhypothermia group according to whether hypothermia occurred during the operation. Anesthesia recovery time and the incidence of adverse events or unwanted events during anesthesia recovery between the two groups were compared.
    Results: The numbers (percentage) of 384 patients who underwent abdominal surgery developed intraoperative hypothermia occurred in 240 (62.5%) patients, all of whom had mild hypothermia. There were statistically significant differences between mild hypothermia after active warming and nonhypothermia in the occurrence of shivering (χ2 = 5.197, P = 0.023) and anesthesia recovery time (Z = -2.269, P = 0.02) in elderly patients undergoing abdominal surgery during anesthesia recovery, and there were no statistically significant differences in hypoxemia, nausea or vomiting, hypertension, hypokalemia, hypocalcemia, analgesic drug use,postoperative wound infection or postoperative hospitalization days.
    Conclusions: The incidence of intraoperative mild hypothermia after active warming was high in elderly patients who underwent abdominal surgery. Mild hypothermia increased the incidence of shivering and prolonged anesthesia recovery time in elderly patients undergoing abdominal surgery.
    MeSH term(s) Humans ; Aged ; Hypothermia/epidemiology ; Hypothermia/etiology ; Body Temperature ; Anesthesia, General/adverse effects ; Shivering ; Surgical Wound Infection/etiology
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2091252-3
    ISSN 1471-2253 ; 1471-2253
    ISSN (online) 1471-2253
    ISSN 1471-2253
    DOI 10.1186/s12871-024-02509-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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