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Article ; Online: Characteristics and adjustment strategies of reservoir agglomeration driving state in narrow channel sand body

Wang Jinhua

E3S Web of Conferences, Vol 394, p

2023 Volume 01021

Abstract: With the continuous growth of economy, we are more and more aware of the importance of energy and its preciousness. In the production of crude oil, the narrow channel is the best location for oil storage, and the underlying sand body often has oil ... ...

Abstract	With the continuous growth of economy, we are more and more aware of the importance of energy and its preciousness. In the production of crude oil, the narrow channel is the best location for oil storage, and the underlying sand body often has oil resources. In this paper, the effect of reservoir polymer flooding is taken as the purpose, the principle of polymer flooding technology as the theoretical basis, through the analysis of dynamic change characteristics, in order to improve the adjustment parameters, to achieve reasonable and efficient exploitation of oil Wells. The application of this technology, through the development of practice, has been recognized as an effective method of oil recovery.
Keywords	narrow channel sand body ; oil extraction ; poly flooding mining ; Environmental sciences ; GE1-350
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Analysis of Clinical Characteristics and Prognostic Factors Related to EMs Correlation in Ovarian Cancer Patients.

Zheng, Qiaomei / Chen, Shaozhan / Chen, Lihong / Wang, Jinhua

Alternative therapies in health and medicine

2024

Abstract: Objective: To investigate the clinical characteristics and prognostic factors in patients with endometriosis-associated ovarian cancer.: Methods: In this study, we retrospectively analyzed the medical records of 135 ovarian cancer patients admitted ... ...

Abstract	Objective: To investigate the clinical characteristics and prognostic factors in patients with endometriosis-associated ovarian cancer. Methods: In this study, we retrospectively analyzed the medical records of 135 ovarian cancer patients admitted to our hospital from January 2016 to January 2018. Based on the presence of concomitant endometriosis (EMs), the patients were divided into two groups: the Endometriosis-Associated Ovarian Cancer (EAOC) group (n=64) and the non-EAOC (NEAOC) group (n=71). We compared the clinical characteristics of the two groups. Additionally, in the EAOC group, we followed up with patients for 5 years, categorized them into the survival group (n=40) and the deceased group (n=24) based on their prognosis, and conducted univariate and multivariate logistic regression analyses to identify influencing factors. Results: In comparison to the NEAOC group, patients in the EAOC group exhibited higher rates of menopause occurrence, pathological stages I-II, vaginal bleeding, and history of cesarean section, with statistical significance (P < .05). They also had a lower incidence of dysmenorrhea, lymph node metastasis, and abdominal distension, as well as an earlier age of onset, all of which were statistically significant (P < .05). There were no statistically significant differences (P > .05) between the two groups in terms of parity, gravidity, tumor diameter, abdominal pain incidence, and body mass index. Based on prognosis, the patients were categorized into a survival group (n=40) and a deceased group (n=24). Comparison between the two groups showed statistically significant differences (P < .05) in terms of postoperative residue, epithelial-mesenchymal transition, and lymph node metastasis. In contrast, there were no statistically significant differences (P > .05) in terms of tumor laterality, histological type, tumor stage, differentiation degree, and vaginal bleeding. The variables with P < .05 were assigned as independent variables, with the prognosis of death as the dependent variable. Multivariate logistic regression analysis revealed that epithelial-mesenchymal transition and lymph node metastasis were independent risk factors for mortality in EAOC patients (P < .05). Conclusion: Clinical characteristics of EAOC patients show significant differences, with epithelial-mesenchymal transition and lymph node metastasis being identified as independent adverse prognostic factors associated with poor outcomes in EAOC patients. However, this study has limitations such as a relatively small sample size, and further research is therefore necessary.
Language	English
Publishing date	2024-01-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	1225073-9
ISSN	1078-6791
ISSN	1078-6791
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Thesis: Effect of Fusarium infection and fungicide treatment on quality parameters of winter wheat (Triticum aestivum L.)

Wang, Jinhua

2004

Title variant	Effect of Fusarium-infection and fungicide treatment on quality parameters of winter wheat (Triticum aestivum L.)
Author's details	by Jinhua Wang
Keywords	Winterweizen ; Fungizid ; Ernteertrag ; Qualität
Subject	Produktqualität ; Ertrag ; Pflanzenertrag ; Fungistatikum ; Fungizide Verbindungen ; Antifugale Verbindungen
Language	English
Size	103 S. : Ill., graph. Darst., 21 cm
Edition	1. Aufl.
Publisher	Cuvillier
Publishing place	Göttingen
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Göttingen, Univ., Diss., 2004
Note	Zsfassung in dt. Sprache
HBZ-ID	HT014368102
ISBN	3-86537-180-9 ; 978-3-86537-180-5
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

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Article: Improvement Effect of PERMA Model-Based Nursing Intervention plus Music Therapy on Patients with Acute Liver Failure Undergoing Plasma Exchange Therapy.

Wang, Jinhua / Li, Wei

publication RETRACTED

Emergency medicine international

2022 Volume 2022, Page(s) 2485056

Abstract: Objective: To explore the improvement effect of PERMA model-based nursing intervention plus music therapy (MT) on patients with acute liver failure (AHF) undergoing plasma exchange therapy (PET).: Methods: This research included 100 AHF patients ... ...

Abstract	Objective: To explore the improvement effect of PERMA model-based nursing intervention plus music therapy (MT) on patients with acute liver failure (AHF) undergoing plasma exchange therapy (PET). Methods: This research included 100 AHF patients treated with PET in our hospital, between January 2020 and December 2021, including 54 cases receiving PERMA model-based nursing intervention plus MT (observation group, OG) and 46 cases receiving routine nursing (control group, CG). Clinical efficacy and liver function (LF) were compared between the groups. Prenursing and postnursing psychology, treatment compliance, sleep, pain, and quality of life were assessed, and patient satisfaction was investigated at discharge. Results: The postnursing overall efficacy showed no evident difference between the groups ( Conclusions: PERMA model-based nursing intervention plus MT can effectively improve the psychological state, treatment compliance, and quality of life of AHF patients with PET and reduce pain sensation, which has promising clinical application value in the future.
Language	English
Publishing date	2022-06-29
Publishing country	Egypt
Document type	Journal Article ; Retracted Publication
ZDB-ID	2596429-X
ISSN	2090-2859 ; 2090-2840
ISSN (online)	2090-2859
ISSN	2090-2840
DOI	10.1155/2022/2485056
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: HMGB1 enhances the migratory and invasive abilities of A2780/DDP cells by facilitating epithelial to mesenchymal transition via GSK‑3β.

Wang, Jinhua / Zheng, Qiaomei / Zhao, Yanjing / Chen, Shaozhan / Chen, Lihong

Experimental and therapeutic medicine

2024 Volume 27, Issue 3, Page(s) 102

Abstract: The aim of the present study was to investigate the impact and mechanism of high mobility group box 1 (HMGB1) on the regulation of cell migration and invasion in A2780/DDP cisplatin-resistant ovarian cancer cells. After transfecting small interfering (si) ...

Abstract	The aim of the present study was to investigate the impact and mechanism of high mobility group box 1 (HMGB1) on the regulation of cell migration and invasion in A2780/DDP cisplatin-resistant ovarian cancer cells. After transfecting small interfering (si)RNA-HMGB1 into A2780/DDP cells, Transwell migration and invasion assays were conducted to assess alterations in the cell migratory and invasive abilities. Additionally, western blotting analyses were performed to examine changes in HMGB1, phosphorylated (p)-GSK-3β, GSK-3β, E-cadherin and vimentin expression levels. The results of the present study demonstrated that the migratory and invasive abilities of A2780/DDP cells were significantly higher compared with those of A2780 cells. Additionally, the expression levels of HMGB1, p-GSK-3β and the mesenchymal phenotype marker, vimentin, in A2780/DDP cells were significantly elevated relative to the levels in A2780 cells. Conversely, the expression level of the epithelial phenotype marker, E-cadherin, was markedly decreased compared with that in A2780 cells. Following transfection of A2780/DDP cells with siRNA-HMGB1, there was a significant reduction in the rate of cell migration and invasion. Simultaneously, the expression levels of HMGB1, p-GSK-3β and vimentin were downregulated while the level of E-cadherin was upregulated. It was therefore concluded that the high expression of HMGB1 in A2780/DDP cells enhanced the cell migration and invasion abilities by facilitating epithelial to mesenchymal transition via GSK-3β.
Language	English
Publishing date	2024-01-15
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2683844-8
ISSN	1792-1015 ; 1792-0981
ISSN (online)	1792-1015
ISSN	1792-0981
DOI	10.3892/etm.2024.12390
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Article ; Online: Synthesis of Novel Acetyl-11-keto-β-boswellic Acid Derivatives as Potential Anti-GBM Agents.

Sun, Mingxia / Zhang, Sen / Wang, Jinhua / Du, Guanhua / Ji, Tengfei

Chemistry & biodiversity

2024 Volume 21, Issue 4, Page(s) e202301979

Abstract: Acetyl-11-keto-β-boswellic acid (AKBA) is known to inhibit the growth of glioblastoma (GBM) cells and subcutaneous GBM. A series of acetyl-11-keto-β-boswellic acid (AKBA) derivatives containing the oxime-ester functionality or amide side chains were ... ...

Abstract	Acetyl-11-keto-β-boswellic acid (AKBA) is known to inhibit the growth of glioblastoma (GBM) cells and subcutaneous GBM. A series of acetyl-11-keto-β-boswellic acid (AKBA) derivatives containing the oxime-ester functionality or amide side chains were synthesized, and their anti-GBM activities were evaluated. Some of these compounds exhibited significant inhibitory activity against cell proliferation in U87 and U251 GBM cell lines, with IC
MeSH term(s)	Humans ; Glioblastoma/drug therapy ; Triterpenes/chemistry ; Cell Line, Tumor ; Amides ; Autoantibodies ; Piperidones ; Benzeneacetamides
Chemical Substances	acetyl-11-ketoboswellic acid ; antiglomerular basement membrane antibody ; antineoplaston A10 (16VY3TM7ZO) ; Triterpenes ; Amides ; Autoantibodies ; Piperidones ; Benzeneacetamides
Language	English
Publishing date	2024-03-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2139001-0
ISSN	1612-1880 ; 1612-1872
ISSN (online)	1612-1880
ISSN	1612-1872
DOI	10.1002/cbdv.202301979
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Article ; Online: Effect of Vaginal Microecological Alterations on Female Pelvic Organ Prolapse.

Chen, Shaozhan / Zheng, Qiaomei / Zhang, Limin / Chen, Lihong / Wang, Jinhua

International urogynecology journal

2024 Volume 35, Issue 4, Page(s) 881–891

Abstract: Introduction and hypothesis: The objective was to investigate the correlation between endogenous vaginal microecological alterations and female pelvic organ prolapse (POP).: Methods: Patients who underwent vaginal hysterectomy were retrospectively ... ...

Abstract	Introduction and hypothesis: The objective was to investigate the correlation between endogenous vaginal microecological alterations and female pelvic organ prolapse (POP). Methods: Patients who underwent vaginal hysterectomy were retrospectively analyzed as the POP group (n = 30) and the non-POP group (n = 30). The vaginal microbial metabolites and enzyme levels were tested using the dry chemoenzymatic method. The mRNA and protein expression were tested using real-time quantitative PCR and immunohistochemistry. SPSS version 25.0 and GraphPad Prism 8.0 were performed for statistical analysis. Results: Compared with the non-POP group, the vaginal pH, H Conclusions: Vaginal microecological dysbiosis affects the occurrence of female POP, which could be considered a novel therapeutic option.
MeSH term(s)	Female ; Humans ; Pelvic Organ Prolapse/metabolism ; Vagina ; Middle Aged ; Retrospective Studies ; Matrix Metalloproteinase 3/metabolism ; Decorin/metabolism ; Decorin/genetics ; Aged ; Transforming Growth Factor beta1/metabolism ; Transforming Growth Factor beta1/genetics ; Hydrogen Peroxide/metabolism ; Hydrogen-Ion Concentration ; Hysterectomy, Vaginal ; Collagen Type I/metabolism ; Collagen Type I/genetics ; Collagen Type III/metabolism ; Collagen Type III/genetics ; RNA, Messenger/metabolism ; Ligaments/metabolism ; Microbiota ; Adult
Chemical Substances	Matrix Metalloproteinase 3 (EC 3.4.24.17) ; Decorin ; Transforming Growth Factor beta1 ; Hydrogen Peroxide (BBX060AN9V) ; Collagen Type I ; Collagen Type III ; RNA, Messenger
Language	English
Publishing date	2024-03-15
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1050631-7
ISSN	1433-3023 ; 0937-3462
ISSN (online)	1433-3023
ISSN	0937-3462
DOI	10.1007/s00192-024-05759-7
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Article ; Online: Determination of the Absorption, Translocation, and Distribution of Imidacloprid in Wheat.

Wang, Jinhua / Cheng, Chao / Zhao, Changyu / Wang, Lanjun

Journal of visualized experiments : JoVE

2023 , Issue 194

Abstract: Neonicotinoids, a class of insecticides, are widely used because of their novel modes of action, high insecticidal activity, and strong root uptake. Imidacloprid, the most widely used insecticide worldwide, is a representative first-generation ... ...

Abstract	Neonicotinoids, a class of insecticides, are widely used because of their novel modes of action, high insecticidal activity, and strong root uptake. Imidacloprid, the most widely used insecticide worldwide, is a representative first-generation neonicotinoid and is used in pest control for crops, vegetables, and fruit trees. With such a broad application of imidacloprid, its residue in crops has attracted increasing scrutiny. In the present study, 15 wheat seedlings were placed in a culture medium containing 0.5 mg/L or 5 mg/L imidacloprid for hydroculture. The content of imidacloprid in the wheat roots and leaves was determined after 1 day, 2 days, and 3 days of hydroculture to explore the migration and distribution of imidacloprid in wheat. The results showed that imidacloprid was detected both in the roots and leaves of the wheat plant, and the content of imidacloprid in the roots was higher than that in the leaves. Furthermore, the imidacloprid concentration in the wheat increased with increasing exposure time. After 3 days of exposure, the roots and leaves of the wheat in the 0.5 mg/L treatment group contained 4.55 mg/kg ± 1.45 mg/kg and 1.30 mg/kg ± 0.08 mg/kg imidacloprid, respectively, while the roots and leaves of the 5 mg/L treatment group contained 42.5 mg/kg ± 0.62 mg/kg and 8.71 mg/kg ± 0.14 mg/kg imidacloprid, respectively. The results from the present study allow for a better understanding of pesticide residues in crops and provide a data reference for the environmental risk assessment of pesticides.
MeSH term(s)	Triticum ; Neonicotinoids ; Nitro Compounds ; Insecticides/pharmacology ; Crops, Agricultural
Chemical Substances	imidacloprid (3BN7M937V8) ; Neonicotinoids ; Nitro Compounds ; Insecticides
Language	English
Publishing date	2023-04-28
Publishing country	United States
Document type	Journal Article ; Video-Audio Media ; Research Support, Non-U.S. Gov't
ZDB-ID	2259946-0
ISSN	1940-087X ; 1940-087X
ISSN (online)	1940-087X
ISSN	1940-087X
DOI	10.3791/64741
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Article ; Online: A risk prediction nomogram of endometrial carcinoma and precancerous lesions in postmenopausal women: A retrospective study.

Wang, Jinhua / Gao, Songkun / Wang, Jiandong / Wang, Tong

Medicine

2023 Volume 102, Issue 8, Page(s) e33087

Abstract: This study aimed to develop a risk prediction nomogram for endometrial carcinoma and precancerous lesions in postmenopausal women to provide postmenopausal patients with more information on disease probability, work out personalized medical plans, and ... ...

Abstract	This study aimed to develop a risk prediction nomogram for endometrial carcinoma and precancerous lesions in postmenopausal women to provide postmenopausal patients with more information on disease probability, work out personalized medical plans, and reduce unnecessary invasive clinical examinations. We enrolled 340 patients who underwent hysteroscopy at Beijing Maternity Hospital between March 2016 and July 2018. The patients were divided into the low-risk (275 patients) and high-risk (65 patients) groups, according to the results of the pathological examinations. Binary logistic analysis was performed to evaluate the 20 potential risk factors for endometrial cancer and precancerous lesions in postmenopausal women and to screen for certain risk factors using the Statistical Package for the Social Sciences version 26.0. Using R 4.0.3, we built a prediction nomogram that incorporated the selected factors. The discrimination, calibration, and clinical usefulness of the prediction model were assessed using the concordance (C)-index, calibration plot, and decision curve analysis. Internal validation was assessed using bootstrapping validation. Predictors included in the prediction nomogram included obesity, vaginal bleeding, family history of gynecological malignancies, endometrial thickness ≥ 1.15 cm, and color Doppler flow imaging blood flow. The model displayed good discrimination, with a C-index of 0.853, and good calibration. Decision curve analysis showed that the model was clinically useful, with a benefit range of 2% to 93%. A high C-index value of 0.844 could still be reached in the interval validation. Obesity, vaginal bleeding, family history of gynecological malignancies, endometrial thickness ≥ 1.15 cm, and color Doppler flow imaging blood flow were independent risk factors for endometrial cancer and precancerous lesions. Thus, the prediction nomogram can be conveniently used to facilitate individual risk prediction in patients with endometrial cancer and precancerous lesions.
MeSH term(s)	Pregnancy ; Humans ; Female ; Nomograms ; Retrospective Studies ; Postmenopause ; Genital Neoplasms, Female/complications ; Endometrial Neoplasms/pathology ; Precancerous Conditions/complications ; Obesity/complications ; Uterine Hemorrhage/etiology
Language	English
Publishing date	2023-02-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000033087
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Article ; Online: Photocleavable Anionic Glues for Light-Responsive Nanoparticle Aggregates.

Wang, Jinhua / Peled, Tzuf Shay / Klajn, Rafal

Journal of the American Chemical Society

2023

Abstract: Integrating light-sensitive molecules within nanoparticle (NP) assemblies is an attractive approach to fabricate new photoresponsive nanomaterials. Here, we describe the concept of photocleavable anionic glue (PAG): small trianions capable of mediating ... ...

Abstract	Integrating light-sensitive molecules within nanoparticle (NP) assemblies is an attractive approach to fabricate new photoresponsive nanomaterials. Here, we describe the concept of photocleavable anionic glue (PAG): small trianions capable of mediating interactions between (and inducing the aggregation of) cationic NPs by means of electrostatic interactions. Exposure to light converts PAGs into dianionic products incapable of maintaining the NPs in an assembled state, resulting in light-triggered disassembly of NP aggregates. To demonstrate the proof-of-concept, we work with an organic PAG incorporating the UV-cleavable
Language	English
Publishing date	2023-02-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.2c11973
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