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  1. Article ; Online: Active Learning for Efficient Soil Monitoring in Large Terrain with Heterogeneous Sensor Network.

    Chen, Hui / Wang, Ju

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 5

    Abstract: Soils are a complex ecosystem that provides critical services, such as growing food, supplying antibiotics, filtering wastes, and maintaining biodiversity; hence monitoring soil health and domestication is required for sustainable human development. Low- ... ...

    Abstract Soils are a complex ecosystem that provides critical services, such as growing food, supplying antibiotics, filtering wastes, and maintaining biodiversity; hence monitoring soil health and domestication is required for sustainable human development. Low-cost and high-resolution soil monitoring systems are challenging to design and build. Compounded by the sheer size of the monitoring area of interest and the variety of biological, chemical, and physical parameters to monitor, naive approaches to adding or scheduling more sensors will suffer from cost and scalability problems. We investigate a multi-robot sensing system integrated with an active learning-based predictive modeling technique. Taking advantage of advances in machine learning, the predictive model allows us to interpolate and predict soil attributes of interest from the data collected by sensors and soil surveys. The system provides high-resolution prediction when the modeling output is calibrated with static land-based sensors. The active learning modeling technique allows our system to be adaptive in data collection strategy for time-varying data fields, utilizing aerial and land robots for new sensor data. We evaluated our approach using numerical experiments with a soil dataset focusing on heavy metal concentration in a flooded area. The experimental results demonstrate that our algorithms can reduce sensor deployment costs via optimized sensing locations and paths while providing high-fidelity data prediction and interpolation. More importantly, the results verify the adapting behavior of the system to the spatial and temporal variations of soil conditions.
    Language English
    Publishing date 2023-02-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23052365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Potential health risks of foodborne performance-enhancing drugs in competitive sports.

    Wei, Maoqiong / Wang, Ju'an

    Heliyon

    2023  Volume 9, Issue 10, Page(s) e21104

    Abstract: Athletes need to consume a significant amount of energy during prolonged training and in high-intensity competition. It is necessary for them to take nutritional foods that recharge their bodies. However, in sporting events of recent years, both domestic ...

    Abstract Athletes need to consume a significant amount of energy during prolonged training and in high-intensity competition. It is necessary for them to take nutritional foods that recharge their bodies. However, in sporting events of recent years, both domestic and international, many positive drug tests are found to be caused by the ingestion of foods that contain performance-enhancing drugs (PEDs). As a result, the prevention and control of PEDs in food supply have drawn increasing attention. For better prevention and control, the first step is to understand the food contaminants -- PEDs. This study has categorized PEDs through their presence in animal-derived foods, plant-derived foods, and synthetic nutritional supplements in competitive sports. It investigates the potential risks of foodborne doping using techniques such as external addition and endogenous component analysis. This research explored the causes of PEDs in food and their negative effects on athletes and proposed measures to ensure the safety of nutritional substances in competitive sports. PEDs in animal-derived foods include β-adrenergic agonists, anabolic steroids, and glucocorticoids, which can be found in meat and ox penis, amongst other food sources. In contrast, PEDs in plant-derived foods include alkaloids, higenamine, and zeranol, which can be found in coffee, tea, Sichuan pepper, custard apple, and cereal. Performance-enhancing drugs (PEDs) that are often added to synthetic supplements include creatine, traditional Chinese herbs, 1, 3-dimethylbutylamine (DMAA), sibutramine, ephedrine, and methylhexanamine. Targeted anti-doping training should be provided to athletes. In addition, the latest domestic and international standards and regulations regarding PEDs or prohibited and restricted ingredients in foods should be tracked in real-time. The control list for performance-enhancing drugs in food should be continually updated and refined. Research on detection methods for performance-enhancing drugs in food should also be advanced. Moreover, market surveillance and law enforcement should be strengthened to ensure that sports foods meet national safety standards before they enter the market. This paper provides workable solutions to clarify the types and scope of performance-enhancing drugs in food, aiming to improve the prevention and control of PEDs in animal-derived foods, plant-derived foods, and supplements in major sporting events.
    Language English
    Publishing date 2023-10-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e21104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Heterlimnius luyashanensis sp. n. and Zaitzevia triangularis sp. n. from Shanxi Province, China (Coleoptera: Elmidae).

    Peng, Yun-Fei / Bian, Dong-Ju / Wang, Ju-Ping

    Zootaxa

    2024  Volume 5403, Issue 4, Page(s) 488–494

    Abstract: Two new species, Heterlimnius luyashanensis sp. n. and Zaitzevia triangularis sp. n. are described from Shanxi Province, China. The genus Heterlimnius Hinton, 1935 and Zaitzevia Champion, 1923 are reported from Shanxi Province for the first time. ... ...

    Abstract Two new species, Heterlimnius luyashanensis sp. n. and Zaitzevia triangularis sp. n. are described from Shanxi Province, China. The genus Heterlimnius Hinton, 1935 and Zaitzevia Champion, 1923 are reported from Shanxi Province for the first time. Heterlimnius luyashanensis sp. n. belonging to the Heterlimnius trachys species group has the following characteristics: 1. anterior margin of pronotum strongly produced anteriad; 2. median longitudinal sulcus of pronotum extends from basal 0.3 to 0.8. Zaitzevia triangularis sp. n. has a larger body size and a triangular apex of penis.
    MeSH term(s) Male ; Animals ; Coleoptera ; China ; Body Size ; Penis ; Animal Distribution
    Language English
    Publishing date 2024-01-23
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5403.4.7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Advanced lung cancer inflammation index predicts survival outcomes of hepatocellular carcinoma patients receiving immunotherapy.

    Li, Qian / Ma, Fei / Wang, Ju Feng

    Frontiers in oncology

    2023  Volume 13, Page(s) 997314

    Abstract: Objective: We evaluate the predictive significance of the Advanced Lung Cancer Inflammation Index (ALI) in patients with advanced hepatocellular carcinoma (HCC) following therapy with immune checkpoint drugs.: Methods: In 2018-2020, 98 patients with ... ...

    Abstract Objective: We evaluate the predictive significance of the Advanced Lung Cancer Inflammation Index (ALI) in patients with advanced hepatocellular carcinoma (HCC) following therapy with immune checkpoint drugs.
    Methods: In 2018-2020, 98 patients with advanced hepatocellular carcinoma who were treated with immune checkpoint inhibitors at our hospital were compiled. Using the receiver operating characteristic (ROC) curve, the appropriate cut-off point for ALI was determined. Kaplan-Meier analysis, the Cox proportional hazards model, and Nomogram plots highlighted the relationship between ALI and overall survival (OS). The model was validated using calibration plots, receiver operating characteristic curves (ROC), and decision curve analysis (DCA), which was performed on 52 patient sets by external validation.
    Results: The AUC for ALI was 0.663. The best cutoff value was 36.5, with a median overall survival (OS) of 473 days for patients with ALI≤ 36.5 and 611 days for those with ALI > 36.5. Univariate analysis revealed that the presence or absence of local treatment, alpha-fetoprotein (AFP), and ALI were prognostic factors; LASSO regression analysis identified four candidate variables. Multifactorial COX analysis revealed that high ALI was an independent prognostic factor for overall survival in both groups (HR = 0.411; 95% CI: 0.244-0.651; P<0.001). In addition, the Nomogram model that included ALI was able to predict the success of immunotherapy in patients with advanced liver cancer more accurately.
    Conclusion: ALI is a novel prognostic marker in immunotherapy-treated patients with advanced hepatocellular cancer.
    Language English
    Publishing date 2023-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.997314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Analysis of Pollution Characteristics and Emissions Reduction Measures in the Main Cotton Area of Xinjiang.

    Fang, Chunsheng / Li, Zhuoqiong / Shi, Weihao / Wang, Ju

    International journal of environmental research and public health

    2023  Volume 20, Issue 3

    Abstract: With cotton production in Xinjiang increasing annually, the impact on the environment of agricultural waste produced to improve production has been reflected. This study selected Bozhou of Xinjiang, the main cotton producing region in northern Xinjiang, ... ...

    Abstract With cotton production in Xinjiang increasing annually, the impact on the environment of agricultural waste produced to improve production has been reflected. This study selected Bozhou of Xinjiang, the main cotton producing region in northern Xinjiang, as the research object, and collected hourly concentration data of six pollutants from 2017 to 2021, and analyzed the spatial and temporal distribution characteristics of each pollutant. At the same time, Morlet wavelet analysis was used to further analyze the variation period of PM
    MeSH term(s) Air Pollutants/analysis ; Air Pollution/analysis ; Carbon Monoxide/analysis ; Particulate Matter/analysis ; Environmental Pollutants/analysis ; Gossypium ; Environmental Monitoring/methods ; China
    Chemical Substances Air Pollutants ; Carbon Monoxide (7U1EE4V452) ; Particulate Matter ; Environmental Pollutants
    Language English
    Publishing date 2023-01-27
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20032273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Study on the Interaction of a Peptide Targeting Specific G-Quadruplex Structures Based on Chromatographic Retention Behavior.

    Wang, Ju / Qiao, Junqin / Zheng, Weijuan / Lian, Hongzhen

    International journal of molecular sciences

    2023  Volume 24, Issue 2

    Abstract: G-quadruplexes (G4s) are of vital biological significance and G4-specific ligands with conformational selectivity show great application potential in disease treatment and biosensing. RHAU, a RNA helicase associated with AU-rich element, exerts ... ...

    Abstract G-quadruplexes (G4s) are of vital biological significance and G4-specific ligands with conformational selectivity show great application potential in disease treatment and biosensing. RHAU, a RNA helicase associated with AU-rich element, exerts biological functions through the mediation of G4s and has been identified to be a G4 binder. Here, we investigated the interactions between the RHAU peptide and G4s with different secondary structures using size exclusion chromatography (SEC) in association with circular dichroism (CD), ultraviolet-visible (UV-Vis) absorption, and native polyacrylamide gel electrophoresis (Native-PAGE). Spectral results demonstrated that the RHAU peptide did not break the main structure of G4s, making it more reliable for G4 structural analysis. The RHAU peptide was found to display a structural selectivity for a preferential binding to parallel G4s as reflected by the distinct chromatographic retention behaviors. In addition, the RHAU peptide exhibited different interactions with intermolecular parallel G4s and intramolecular parallel G4s, providing a novel recognition approach to G4 structures. The findings of this study enriched the insight into the binding of RHAU to G4s with various conformations. It is noteworthy that SEC technology can be easy and reliable for elucidating G4-peptide interactions, especially for a multiple G4 coexisting system, which supplied an alternative strategy to screen novel specific ligands for G4s.
    MeSH term(s) G-Quadruplexes ; DEAD-box RNA Helicases/metabolism ; Peptides/chemistry
    Chemical Substances DEAD-box RNA Helicases (EC 3.6.4.13) ; Peptides
    Language English
    Publishing date 2023-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24021438
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  7. Article ; Online: Influencing factors of cardiac valve calcification (CVC) in patients with chronic kidney disease and the impact of CVC on long-term prognosis: a single-center retrospective study.

    Wang, Ju / Xiao, Jianping / Wang, Ruifeng / Wang, Deguang

    PeerJ

    2023  Volume 11, Page(s) e15569

    Abstract: Objective: To investigate the effect of cardiac valve calcification (CVC) on the prognosis of patients with chronic kidney disease (CKD).: Methods: A total of 343 CKD patients were retrospectively analyzed, and divided into two groups according to ... ...

    Abstract Objective: To investigate the effect of cardiac valve calcification (CVC) on the prognosis of patients with chronic kidney disease (CKD).
    Methods: A total of 343 CKD patients were retrospectively analyzed, and divided into two groups according to the presence or absence of cardiac valve calcification. All patients were followed until death, loss to follow-up, or the end point of the study (December 2021).
    Results: The incidence of CVC among the 343 CKD patients was 29.7%, including 21 cases of mitral valve calcification, 63 cases of aortic valve calcification, and 18 cases of mitral valve combined with aortic valve calcification. The incidence of CVC in CKD stages 1-2 was 0.3%, 5.2% in CKD stages 3-4, and 24.2% in CKD stage 5 (
    Conclusion: The incidence of CVC, mainly aortic calcification, is high in patients with CKD. Advanced age, higher serum albumin and higher cystatin C levels were associated with a higher risk of CVC. Hyperuricemia was associated with a lower risk of CVC. The overall survival rate of patients with CVC was lower than that of patients without CVC.
    MeSH term(s) Humans ; Retrospective Studies ; Cystatin C ; Renal Dialysis ; Heart Valve Diseases/epidemiology ; Renal Insufficiency, Chronic/epidemiology ; Aortic Valve/diagnostic imaging
    Chemical Substances Cystatin C
    Language English
    Publishing date 2023-06-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.15569
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Effects of micro-bubble aeration on the pollutant removal and energy-efficient process in a floc-granule sludge coexistence system.

    Liu, Minghui / Wang, Ju / Peng, Zhaoxu

    Water science and technology : a journal of the International Association on Water Pollution Research

    2023  Volume 88, Issue 11, Page(s) 3044–3055

    Abstract: To investigate energy-saving approaches in wastewater treatment plants and decrease aeration energy consumption, this study successfully established a floc-granule coexistence system in a sequencing batch airlift reactor (SBAR) employing micro-bubble ... ...

    Abstract To investigate energy-saving approaches in wastewater treatment plants and decrease aeration energy consumption, this study successfully established a floc-granule coexistence system in a sequencing batch airlift reactor (SBAR) employing micro-bubble aeration. The analysis focused on granule formation and pollutant removal under various aeration intensities, and compared its performance with a traditional floc-based coarse-bubble aeration system. The results showed that granulation efficiency was positively associated with aeration intensity, which enhanced the secretion of extracellular polymeric substances (EPSs) and facilitated granule formation. The SBAR with the micro-aeration intensity of 30 mL·min
    MeSH term(s) Sewage ; Waste Disposal, Fluid/methods ; Bioreactors ; Bacteria ; Aerobiosis ; Nitrogen
    Chemical Substances Sewage ; Nitrogen (N762921K75)
    Language English
    Publishing date 2023-12-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 764273-8
    ISSN 1996-9732 ; 0273-1223
    ISSN (online) 1996-9732
    ISSN 0273-1223
    DOI 10.2166/wst.2023.376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Role of Peripheral Blood T Helper 17 Cells in Non-Small Cell Lung Cancer of Different Clinical Stages, Pathological Types and Differentiation Degrees.

    Fu, Kai / Wang, Xuefeng / Li, Jingbo / Wang, Ju

    Clinical laboratory

    2023  Volume 69, Issue 10

    Abstract: Background: We aimed to explore the roles of T helper 17 (Th17) cells and cytokines interleukin 17 (IL-17), IL-6, IL-4, transforming growth factor β (TGF-β) and γ-interferon (IFN-γ) in the peripheral blood of patients with non-small cell lung cancer ( ... ...

    Abstract Background: We aimed to explore the roles of T helper 17 (Th17) cells and cytokines interleukin 17 (IL-17), IL-6, IL-4, transforming growth factor β (TGF-β) and γ-interferon (IFN-γ) in the peripheral blood of patients with non-small cell lung cancer (NSCLC) of different clinical stages, pathological types, and differentiation degrees.
    Methods: A total of 120 NSCLC patients admitted and 80 healthy people receiving physical examinations from June 2019 to October 2021 were enrolled as the case group (TNM stage: I, II, III and IV; pathological type: adenocarcinoma and squamous cell carcinoma; differentiation degree: low and moderate-high) and the control group, respectively. The serum levels of IL-17, IL-6, IL-4, TGF-β and IFN-γ were measured using an enzyme-linked immunosorbent assay. Th17 cells were counted by flow cytometry.
    Results: The case group had higher levels of Th17 cells, IL-17, IL-6, IL-4, and TGF-β and lower IFN-γ level in the peripheral blood than those of the control group (p < 0.05). NSCLC patients with different TNM stages had significantly different levels of Th17 cell, IL-17, IL-6, TGF-β, and IFN-γ (p < 0.05). The expression levels of Th17 and IL-6 in patients with lowly differentiated NSCLC were lower than those of patients with moderately and highly differentiated NSCLC, while the IFN-γ expression level followed an opposite trend (p < 0.05). The count of Th17 cells in the peripheral blood of NSCLC patients had significantly positive correlations with IL-17, IL-6, IL-4, and TGF-β levels, but negative correlation with IFN-γ level (p < 0.05).
    Conclusions: The count of Th17 cells increases significantly in NSCLC patients and has correlations with TNM stage and differentiation degree.
    MeSH term(s) Humans ; Carcinoma, Non-Small-Cell Lung ; Th17 Cells/metabolism ; Interleukin-17/metabolism ; Interleukin-6 ; Interleukin-4/metabolism ; Lung Neoplasms/pathology ; Transforming Growth Factor beta/metabolism ; Interferon-gamma ; Cell Differentiation
    Chemical Substances Interleukin-17 ; Interleukin-6 ; Interleukin-4 (207137-56-2) ; Transforming Growth Factor beta ; Interferon-gamma (82115-62-6)
    Language English
    Publishing date 2023-10-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1307629-2
    ISSN 1433-6510 ; 0941-2131
    ISSN 1433-6510 ; 0941-2131
    DOI 10.7754/Clin.Lab.2022.220116
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  10. Article: Developmental toxicity and inflammatory response induced by Botrytis cinerea in zebrafish (Danio rerio) larvae.

    Shi, Shengnan / Wang, Ju / Liu, Changhong / Zheng, Lei

    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP

    2023  Volume 267, Page(s) 109575

    Abstract: Botrytis cinerea can reduce the yield of fruits and vegetables by infecting plants. The conidia produced by Botrytis cinerea can be transmitted to the aquatic environment via air and water, but the effects of Botrytis cinerea on aquatic animals is ... ...

    Abstract Botrytis cinerea can reduce the yield of fruits and vegetables by infecting plants. The conidia produced by Botrytis cinerea can be transmitted to the aquatic environment via air and water, but the effects of Botrytis cinerea on aquatic animals is unknown. In this research, the influence of Botrytis cinerea on the development, inflammation, and apoptosis of zebrafish larvae and the underlying mechanism was evaluated. Results indicated that, compared with the control group, the larvae exposed to 10
    MeSH term(s) Animals ; Zebrafish/metabolism ; Larva ; NF-kappa B/metabolism ; Tumor Necrosis Factor-alpha/metabolism
    Chemical Substances NF-kappa B ; Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2023-02-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 189285-x
    ISSN 1532-0456 ; 0306-4492 ; 0742-8413
    ISSN 1532-0456 ; 0306-4492 ; 0742-8413
    DOI 10.1016/j.cbpc.2023.109575
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