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Article ; Online: Mechanosensor for Proprioception Inspired by Ultrasensitive Trigger Hairs of Venus Flytrap.

Wang, Qian / Lu, Zezhong / Wang, Deshan / Wang, Kejun

Cyborg and bionic systems (Washington, D.C.)

2024 Volume 5, Page(s) 65

Abstract: Mechanosensors, as the core component of a proprioceptive system, can detect many types of mechanical signals in their surroundings, such as force signals, displacement signals, and vibration signals. It is understandable that the development of an all- ... ...

Abstract	Mechanosensors, as the core component of a proprioceptive system, can detect many types of mechanical signals in their surroundings, such as force signals, displacement signals, and vibration signals. It is understandable that the development of an all-new mechanosensory structure that can be widely used is highly desirable. This is because it can markedly improve the detection performance of mechanosensors. Coincidentally, in nature, optimized microscale trigger hairs of Venus flytrap are ingeniously used as a mechanosensory structure. These trigger hairs are utilized for tactile mechanosensilla to efficiently detect external mechanical stimuli. Biological trigger hair-based mechanosensilla offer an all-new bio-inspired strategy. This strategy utilizes the notch structure and variable stiffness to enhance the perceptual performance of mechanosensors. In this study, the structure-performance-application coupling relationship of trigger hair-based mechanosensors is explored through experiment and analysis. An artificial trigger hair-based mechanosensor is developed by mimicking the deformation properties of the Venus flytrap trigger hair. This bio-inspired mechanosensor shows excellent performance in terms of mechanical stability, response time, and sensitivity to mechanical signals.
Language	English
Publishing date	2024-01-24
Publishing country	United States
Document type	Journal Article
ISSN	2692-7632
ISSN (online)	2692-7632
DOI	10.34133/cbsystems.0065
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Underwater single-channel acoustic signal multitarget recognition using convolutional neural networks.

Sun, Qinggang / Wang, Kejun

The Journal of the Acoustical Society of America

2022 Volume 151, Issue 3, Page(s) 2245

Abstract: The radiated noise from ships is of great significance to target recognition, and several deep learning methods have been developed for the recognition of underwater acoustic signals. Previous studies have focused on single-target recognition, with ... ...

Abstract	The radiated noise from ships is of great significance to target recognition, and several deep learning methods have been developed for the recognition of underwater acoustic signals. Previous studies have focused on single-target recognition, with relatively few reports on multitarget recognition. This paper proposes a deep learning-based single-channel multitarget underwater acoustic signal recognition method for an unknown number of targets in the specified category. The proposed method allows the two subproblems of recognizing the unique class and duplicate categories of multiple targets to be solved. These two tasks are essentially multilabel binary classification and multilabel multiple value classification, respectively. In this paper, we describe the use of real-valued and complex-valued ResNet and DenseNet convolutional networks to recognize synthetic mixed multitarget signals, which was superimposed from individual target signals. We compare the performance of various features, including the original audio signal, complex-valued short-time Fourier transform (STFT) spectrum, magnitude STFT spectrum, logarithmic mel spectrum, and mel frequency cepstral coefficients. The experimental results show that our method can effectively recognize synthetic multitarget ship signals when the magnitude STFT spectrum, complex-valued STFT spectrum, and log-mel spectrum are used as network inputs.
MeSH term(s)	Acoustics ; Neural Networks, Computer
Language	English
Publishing date	2022-04-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	219231-7
ISSN	1520-8524 ; 0001-4966
ISSN (online)	1520-8524
ISSN	0001-4966
DOI	10.1121/10.0009852
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Article ; Online: A study on the aerodynamic behaviors learned from microscopy imaging of beetle corrugated hindwing.

Liu, Chao / Chen, Guodong / Wang, Qian / Sun, Lining / Wang, Kejun

Microscopy research and technique

2024

Abstract: Beetle hindwings have the unique advantages of lightweight and high strength, which play a key role in flight. In this study, the beetle hindwings were cut along the chordal direction, then the first groove microstructure of different vein cross sections ...

Abstract	Beetle hindwings have the unique advantages of lightweight and high strength, which play a key role in flight. In this study, the beetle hindwings were cut along the chordal direction, then the first groove microstructure of different vein cross sections was investigated using the 3D microscope system and the laser scanning confocal microscope. It was found that the position of the first groove relative to the entire chordal cross section of the wing gradually moves backward, which has an effect on the flying aerodynamic behaviors of the beetle. Next, three corrugated airfoils learned from the microscopy imaging of the ladybird beetle hindwing were designed. Then, aerodynamic behaviors were calculated by the ANSYS Fluent software, and it was confirmed that the position of the first groove microstructure affects the aerodynamic performance of the airfoil. For further study, the influence of corrugated structural and motion parameters on the aerodynamic, 2D 'simplified' airfoil models with triangular wave airfoil models (TWA models) was developed and studied. RESEARCH HIGHLIGHTS: The position of the first groove microstructure affects the aerodynamic performance of the airfoil. The pressure difference of different corrugation patterns shows significantly asymmetric during the upstroke and downstroke. The aerodynamic is optimal of 2D-TWA models, when the number of corrugations is five, the corrugation is right angle, and the flapping frequency is 75 Hz.
Language	English
Publishing date	2024-03-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	1099714-3
ISSN	1097-0029 ; 1059-910X
ISSN (online)	1097-0029
ISSN	1059-910X
DOI	10.1002/jemt.24562
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Article ; Online: Study on driver's active emergency response in dangerous traffic scenes based on driving simulator.

Ma, Shuai / Xu, Shucai / Song, Jiafeng / Wang, Kejun / Qin, Haoyi / Wang, Ruixiang

Traffic injury prevention

2024 Volume 25, Issue 2, Page(s) 116–121

Abstract: Objective: A driver's active emergency response in dangerous traffic scenes consists of two parts, including reaction behavior and physiological state. In dangerous traffic scenes, the driver's active emergency response has an important impact on human ... ...

Abstract	Objective: A driver's active emergency response in dangerous traffic scenes consists of two parts, including reaction behavior and physiological state. In dangerous traffic scenes, the driver's active emergency response has an important impact on human collision injury. Clarifying the driver's active emergency response is an important prerequisite for the study of human collision injury under nonstandard posture. Therefore, this study investigates the driver's active emergency response in different inevitable collision scenes using driving simulator. Methods: A driving simulator with a high-speed camera system and human physiological signal acquisition system was first built. Then, three typical vehicle dangerous collision scenes were developed, including frontal collision, side collision, and rear-end collision. Finally, twenty participants (15 males and 5 females) were recruited for a driving experiment, and their active emergency responses were recorded and analyzed. Results: All subjects would rotate the steering wheel to the left or right in the active emergency state, and the rotation of the hand would also cause the subject's upper body to tilt in the same direction. The maximum angle for male subjects to rotate the steering wheel was 59.98°, while for the female subjects, it was 44.28°. In addition, the maximum grip force between the male subjects and the steering wheel was 280.5 N, compared to 192.5 N for female subjects. Compared to the female participants, the male participants not only have a greater rotation angle and a greater grip force on the steering wheel, but also have greater pressure on the brake pedal, and the foot moves quickly from the accelerator pedal to the brake pedal and presses the brake pedal. Conclusions: Drivers have different active emergency responses to different vehicle collision scenes. Quantitative statistics of driver's active emergency response will have important guiding significance for the analysis of the impact of human active emergency response on human injury characteristics in subsequent vehicle collision experiments.
MeSH term(s)	Humans ; Male ; Female ; Automobile Driving ; Accidents, Traffic/prevention & control ; Reaction Time/physiology ; Lower Extremity/physiology ; Dangerous Behavior
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2089818-6
ISSN	1538-957X ; 1538-9588
ISSN (online)	1538-957X
ISSN	1538-9588
DOI	10.1080/15389588.2023.2282948
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Book ; Online: Source Separation of Unknown Numbers of Single-Channel Underwater Acoustic Signals Based on Autoencoders

Sun, Qinggang / Wang, Kejun

2022

Abstract: The separation of single-channel underwater acoustic signals is a challenging problem with practical significance. In view of the signal separation problem with unknown numbers of signals, we propose a solution with a fixed number of output channels, ... ...

Abstract	The separation of single-channel underwater acoustic signals is a challenging problem with practical significance. In view of the signal separation problem with unknown numbers of signals, we propose a solution with a fixed number of output channels, enabling it to avoid the dimensional disaster caused by the permutation problem induced by the alignment of outputs to targets. Specifically, we modify two algorithms developed for known numbers of signals based on autoencoders, which are highly explainable. We also propose a new performance evaluation method for situations with mute channels. Experiments conducted on simulated mixtures of radiated ship noise show that the proposed solution can achieve similar separation performance to that attained with a known number of signals. The mute channel output is also good. Comment: 6 pages, 2 figures,3 tables. For codes, see https://github.com/QinggangSUN/unknown_number_source_separation. This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible
Keywords	Computer Science - Sound ; Computer Science - Artificial Intelligence ; Computer Science - Machine Learning ; Electrical Engineering and Systems Science - Audio and Speech Processing ; I.2.6 ; I.5.4 ; J.2
Subject code	004
Publishing date	2022-07-24
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Efficacy and influencing factors of the four‐step approach combining the situational simulation teaching method in the clinical practice of standardized training for residents

Tong Shan / Wang Kejun / Feng Ying / Huang Jia / Jiang Hongyan

Health Science Reports, Vol 5, Iss 5, Pp n/a-n/a (2022)

2022

Abstract: Abstract Background and Aims Clinical skills practice is an essential component in standardized residency training. However, traditionally skill training methods are dogmatic and not all residents are exposed to such prescribed situations during their ... ...

Abstract	Abstract Background and Aims Clinical skills practice is an essential component in standardized residency training. However, traditionally skill training methods are dogmatic and not all residents are exposed to such prescribed situations during their residency. The aims of this study were to evaluate the effectiveness and influence factors of a four‐step approach combining situational simulation teaching methods in clinical practice for residents. Methods Enrolled all second‐year residents from the internal medicine base between May 2017 and May 2018 (n = 94), randomly divided into two groups. Forty‐eight residents were selected as experimental group, while the others 46 as the control group. Adopted traditional clinical practice method in the teaching and assessment of the control group, while used four‐step approach combining situational simulation teaching method in experimental group. We compared the theoretical and skill assessment scores in preclass and postclass. Conducted a satisfaction survey after class and analyzed the influencing factors of the teaching effect evaluation. Results There were no significant differences in the theoretical and skill assessment scores between experimental group and control group at the beginning. After the class, both the average skill assessment and Direct Observation of Procedural Skills scores of the experimental group were higher than those of the control. Satisfaction survey findings identified that the experimental group expressed higher satisfaction. Logistic regression showed that educational background, “situational simulation mode helps to improve clinical skills training,” “helps to maintain attention during learning,” and “helps improve the ability to exercise analysis and solve problems” were the influencing factors of learners' satisfaction. Conclusion The application of four‐step approach combining situational simulation teaching methods in the clinical practice of residents can significantly improve skills, thinking ability, decision‐making ability, and ...
Keywords	clinical practice ; four‐step teaching method ; situational simulation teaching method ; standardized training for residents ; Medicine ; R
Subject code	370
Language	English
Publishing date	2022-09-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effect of cloprostenol on luteolysis in jennies

Yang, Feng / Wang, Kejun / Li, Nan / Wu, Shuaihuai / Zeng, Shenming

Journal of Equine Veterinary Science. 2023 June, v. 125 p.104757-

2023

Abstract: An intensive farm system has progressively emerged with the rapid development of the donkey industry. One of the primary challenges impeding the development of the donkey industry and the preservation of endangered donkey species is the low reproductive ... ...

Abstract	An intensive farm system has progressively emerged with the rapid development of the donkey industry. One of the primary challenges impeding the development of the donkey industry and the preservation of endangered donkey species is the low reproductive efficiency of jennies (Feng Yang et.al. Equine Veterinary Journal 2021, 53: 1218-1226). In donkeys, luteolysis occurs between days 15 and 17 after ovulation (Carluccio A. et.al. Theriogenology, 2007, 68(6): 914-919). To shorten the estrus cycle, a new estrus cycle may start after luteolysis is induced by the PGF2α analog (Duccio P. et.al. Theriogenology, 2018, 121: 175-180). Treatment of mares and cattle with PGF2α analogs from the fifth day after ovulation induces luteolysis (Bergfelt DR. et.al. Theriogenology, 2006, 65(8): 1605-1619). However, information regarding luteolysis in jennies is limited. In this study, we aimed to investigate the effect of cloprostenol on luteolysis in jennies. The PGF2α analog used in the experiment was cloprostenol (0.2 mg/2 ml, Ningbo Second Hormone Factory, Zhejiang, China). To study the effects of different cloprostenol doses on the estrus cycle, jennies were treated with 0.2 mg (n=30), 0.4 mg (n=30), or 0.6 mg (n=30)cloprostenol (PGF2α), respectively. The time of luteolysis, ovulation interval, follicular size at ovulation, and ovulation rates were compared between the groups. The results showed that luteolysis rates in the jennies within 72 h of treatment were higher than 90% in the three treatment groups. The time required for luteolysis was not statistically different among the three groups. In addition, the estrus interval, ovulation interval, ovulation diameter, and ovulation rate did not differ among the three groups. To examine the timing effect of cloprostenol treatment on the estrus cycle, jennies were treated with 0.4 mg cloprostenol on the third (D 3, n=30), fifth (D 5, n=30), or seventh (D 7, n=30) day following ovulation, respectively. The results showed that the luteal phase of the D 3 treatment group was shorter than that of the D 5 and D 7 treatment groups, and in the D 5 treatment group was shorter than that of the D 7 group (P < 0.05). In can be concluded that treatment with 0.4 mg cloprostenol on the third day following ovulation shortens the length of the luteal phase and estrus cycle considerably.
Keywords	asses ; cattle ; cloprostenol ; estrus ; farming systems ; horses ; industry ; luteolysis ; menstrual cycle ; ovulation ; reproductive efficiency ; veterinary medicine ; China
Language	English
Dates of publication	2023-06
Publishing place	Elsevier Inc.
Document type	Article ; Online
ZDB-ID	2102631-2
ISSN	1542-7412 ; 0737-0806
ISSN (online)	1542-7412
ISSN	0737-0806
DOI	10.1016/j.jevs.2023.104757
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Effects on the intestinal morphology, inflammatory response and microflora in piglets challenged with enterotoxigenic Escherichia coli K88

Zhang, Kun / Shen, Xiaoyang / Han, Lu / Wang, Mengyun / Lian, Shaoqiang / Wang, Kejun / Li, Chunli

Research in Veterinary Science. 2023 Feb. 28,

2023

Abstract: Enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrhea in piglets, which leads to great economic losses. In this study, the ternary crossbred weaned piglets were orally administered with 1.5 × 10¹¹ CFU ETEC K88 for three days. The ... ...

Abstract	Enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrhea in piglets, which leads to great economic losses. In this study, the ternary crossbred weaned piglets were orally administered with 1.5 × 10¹¹ CFU ETEC K88 for three days. The results showed the ratio of villus length to crypt depth decreased in the duodenum and ileum after ETEC K88 infection. The expression of tight junction proteins ZO-1 in the jejunum and ileum, occludin in the jejunum and colon, and claudin-1 in the colon were down-regulated. The expression of IL-8 in the duodenum and jejunum, IL-13 in the colon, and TNF-α in the jejunum and colon were up-regulated. The expression of pBD1 in the colon, pBD2 in the jejunum, and pBD3 in the duodenum increased after infection. Meanwhile, the expression of TLR4, p38 MAPK and NF-κB p65 increased in all intestinal segments. Moreover, the expression of IL-8 in superficial cervical lymph nodes (SCLN), TNF-α in mesenteric lymph nodes (MLN), and IL-13 in inguinal lymph nodes (ILN) and MLN were up-regulated. The expression of pBD1 and pBD2 in SCLN and MLN, and pBD3 in SCLN were up-regulated. Acidobacteria and Proteobacteria were the most abundant phyla in both groups by analysis of intestinal microflora using 16 s rRNA sequencing, and the relative abundances of bacteria were found to be changed by Metastats software and LEfSe analysis. Our results indicated that cytokines and pBDs had different roles in different intestinal segments or different lymph nodes against ETEC K88, and gut microbiota was influenced after infection.
Keywords	Acidobacteria ; colon ; computer software ; crossbreds ; diarrhea ; duodenum ; enterotoxigenic Escherichia coli ; ileum ; inflammation ; interleukin-13 ; interleukin-8 ; intestinal microorganisms ; jejunum ; lymph ; mitogen-activated protein kinase ; occludins ; research ; tight junctions ; veterinary medicine ; villi ; ETEC K88 infection ; Intestinal morphology ; Cytokines ; Porcine beta defensins ; Toll-like receptors signaling pathway ; Intestinal microflora
Language	English
Dates of publication	2023-0228
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	840961-4
ISSN	1532-2661 ; 0034-5288
ISSN (online)	1532-2661
ISSN	0034-5288
DOI	10.1016/j.rvsc.2023.02.011
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Integrated analysis strategy of genome-wide functional gene mining reveals DKK2 gene underlying meat quality in Shaziling synthesized pigs.

He, Shuaihan / Wang, Yubei / Luo, Yabiao / Xue, Mingming / Wu, Maisheng / Tan, Hong / Peng, Yinglin / Wang, Kejun / Fang, Meiying

BMC genomics

2024 Volume 25, Issue 1, Page(s) 30

Abstract: Background: Shaziling pig is a well-known indigenous breed in China who has superior meat quality traits. However, the genetic mechanism and genomic evidence underlying meat quality characteristics of Shaziling pigs are still unclear. To explore and ... ...

Abstract	Background: Shaziling pig is a well-known indigenous breed in China who has superior meat quality traits. However, the genetic mechanism and genomic evidence underlying meat quality characteristics of Shaziling pigs are still unclear. To explore and investigate the germplasm characteristics of Shaziling pigs, we totally analyzed 67 individual's whole genome sequencing data for the first time (20 Shaziling pigs [S], 20 Dabasha pigs [DBS], 11 Yorkshire pigs [Y], 10 Berkshire pigs [BKX], 5 Basha pigs [BS] and 1 Warthog). Results: A total of 2,538,577 SNPs with high quality were detected and 9 candidate genes which was specifically selected in S and shared in S to DBS were precisely mined and screened using an integrated analysis strategy of identity-by-descent (IBD) and selective sweep. Of them, dickkopf WNT signaling pathway inhibitor 2 (DKK2), the antagonist of Wnt signaling pathway, was the most promising candidate gene which was not only identified an association of palmitic acid and palmitoleic acid quantitative trait locus in PigQTLdb, but also specifically selected in S compared to other 48 Chinese local pigs of 12 populations and 39 foreign pigs of 4 populations. Subsequently, a mutation at 12,726-bp of DKK2 intron 1 (g.114874954 A > C) was identified associated with intramuscular fat content using method of PCR-RFLP in 21 different pig populations. We observed DKK2 specifically expressed in adipose tissues. Overexpression of DKK2 decreased the content of triglyceride, fatty acid synthase and expression of relevant genes of adipogenic and Wnt signaling pathway, while interference of DKK2 got contrary effect during adipogenesis differentiation of porcine preadipocytes and 3T3-L1 cells. Conclusions: Our findings provide an analysis strategy for mining functional genes of important economic traits and provide fundamental data and molecular evidence for improving pig meat quality traits and molecular breeding.
MeSH term(s)	Swine/genetics ; Animals ; Meat ; Quantitative Trait Loci ; Phenotype ; Genome-Wide Association Study ; China
Language	English
Publishing date	2024-01-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2041499-7
ISSN	1471-2164 ; 1471-2164
ISSN (online)	1471-2164
ISSN	1471-2164
DOI	10.1186/s12864-023-09925-x
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Article ; Online: Underwater Acoustic Target Recognition Based on Depthwise Separable Convolution Neural Networks.

Hu, Gang / Wang, Kejun / Liu, Liangliang

Sensors (Basel, Switzerland)

2021 Volume 21, Issue 4

Abstract: Facing the complex marine environment, it is extremely challenging to conduct underwater acoustic target feature extraction and recognition using ship-radiated noise. In this paper, firstly, taking the one-dimensional time-domain raw signal of the ship ... ...

Abstract	Facing the complex marine environment, it is extremely challenging to conduct underwater acoustic target feature extraction and recognition using ship-radiated noise. In this paper, firstly, taking the one-dimensional time-domain raw signal of the ship as the input of the model, a new deep neural network model for underwater target recognition is proposed. Depthwise separable convolution and time-dilated convolution are used for passive underwater acoustic target recognition for the first time. The proposed model realizes automatic feature extraction from the raw data of ship radiated noise and temporal attention in the process of underwater target recognition. Secondly, the measured data are used to evaluate the model, and cluster analysis and visualization analysis are performed based on the features extracted from the model. The results show that the features extracted from the model have good characteristics of intra-class aggregation and inter-class separation. Furthermore, the cross-folding model is used to verify that there is no overfitting in the model, which improves the generalization ability of the model. Finally, the model is compared with traditional underwater acoustic target recognition, and its accuracy is significantly improved by 6.8%.
Language	English
Publishing date	2021-02-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s21041429
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