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Article ; Online: Exceptional points enhance sensing in silicon micromechanical resonators.

Zhang, Man-Na / Dong, Lei / Wang, Li-Feng / Huang, Qing-An

Microsystems & nanoengineering

2024 Volume 10, Page(s) 12

Abstract: Exceptional points (EPs) have recently emerged as a new method for engineering the response of open physical systems, that is, systems that interact with the environment. The systems at the EPs exhibit a strong response to a small perturbation. Here, we ... ...

Abstract	Exceptional points (EPs) have recently emerged as a new method for engineering the response of open physical systems, that is, systems that interact with the environment. The systems at the EPs exhibit a strong response to a small perturbation. Here, we show a method by which the sensitivity of silicon resonant sensors can be enhanced when operated at EPs. In our experiments, we use a pair of mechanically coupled silicon micromechanical resonators constituting a parity-time (PT)-symmetric dimer. Small perturbations introduced on the mechanically coupled spring cause the frequency to split from the EPs into the PT-symmetric regime without broadening the two spectrum linewidths, and this frequency splitting scales with the square root of the perturbation strength. The overall signal-to-noise ratio is still greatly enhanced, although the measured noise spectral density of the EP sensing scheme has a slight increase comparable to the traditional counterpart. Our results pave the way for resonant sensors with ultrahigh sensitivity.
Language	English
Publishing date	2024-01-19
Publishing country	England
Document type	Journal Article
ISSN	2055-7434
ISSN (online)	2055-7434
DOI	10.1038/s41378-023-00641-w
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Article ; Online: Physiological and molecular responses to variation of light intensity in rubber Tree (Hevea brasiliensis Muell. Arg.).

Wang, Li-feng

PloS one

2014 Volume 9, Issue 2, Page(s) e89514

Abstract: Light is one of most important factors to plants because it is necessary for photosynthesis. In this study, physiological and gene expression analyses under different light intensities were performed in the seedlings of rubber tree (Hevea brasiliensis) ... ...

Abstract	Light is one of most important factors to plants because it is necessary for photosynthesis. In this study, physiological and gene expression analyses under different light intensities were performed in the seedlings of rubber tree (Hevea brasiliensis) clone GT1. When light intensity increased from 20 to 1000 µmol m(-2) s(-1), there was no effect on the maximal quantum yield of photosystem II (PSII) photochemistry (Fv/Fm), indicating that high light intensity did not damage the structure and function of PSII reaction center. However, the effective photochemical quantum yield of PSII (Y(II)), photochemical quenching coefficient (qP), electron transfer rate (ETR), and coefficient of photochemical fluorescence quenching assuming interconnected PSII antennae (qL) were increased significantly as the light intensity increased, reached a maximum at 200 µmol m(-2) s(-1), but decreased from 400 µmol m(-2) s(-1). These results suggested that the PSII photochemistry showed an optimum performance at 200 µmol m(-2) s(-1) light intensity. The chlorophyll content was increased along with the increase of light intensity when it was no more than 400 µmol m(-2) s(-1). Since increasing light intensity caused significant increase in H2O2 content and decreases in the per unit activity of antioxidant enzymes SOD and POD, but the malondialdehyde (MDA) content was preserved at a low level even under high light intensity of 1000 µmol m(-2) s(-1), suggesting that high light irradiation did not induce membrane lipid peroxidation in rubber tree. Moreover, expressions of antioxidant-related genes were significantly up-regulated with the increase of light intensity. They reached the maximum expression at 400 µmol m(-2) s(-1), but decreased at 1000 µmol m(-2) s(-1). In conclusion, rubber tree could endure strong light irradiation via a specific mechanism. Adaptation to high light intensity is a complex process by regulating antioxidant enzymes activities, chloroplast formation, and related genes expressions in rubber tree.
MeSH term(s)	Chlorophyll/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Plant/radiation effects ; Hevea/physiology ; Hevea/radiation effects ; Light ; Photochemistry ; Photosynthesis/physiology ; Photosystem II Protein Complex/metabolism ; beta Carotene/metabolism
Chemical Substances	Photosystem II Protein Complex ; beta Carotene (01YAE03M7J) ; Chlorophyll (1406-65-1)
Language	English
Publishing date	2014-02-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0089514
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Article ; Online: Physiological and molecular responses to drought stress in rubber tree (Hevea brasiliensis Muell. Arg.).

Wang, Li-feng

Plant physiology and biochemistry : PPB

2014 Volume 83, Page(s) 243–249

Abstract: Plant drought stress response and tolerance are complex biological processes. In order to reveal the drought tolerance mechanism in rubber tree, physiological responses and expressions of genes involved in energy biosynthesis and reactive oxygen species ( ...

Abstract	Plant drought stress response and tolerance are complex biological processes. In order to reveal the drought tolerance mechanism in rubber tree, physiological responses and expressions of genes involved in energy biosynthesis and reactive oxygen species (ROS) scavenging were systematically analyzed following drought stress treatment. Results showed that relative water content (RWC) in leaves was continuously decreased with the severity of drought stress. Wilting leaves were observed at 7 day without water (dww). Total chlorophyll content was increased at 1 dww, but decreased from 3 dww. However, the contents of malondialdehyde (MDA) and proline were significantly increased under drought stress. Peroxidase (POD) and superoxide dismutase (SOD) activities were markedly enhanced at 1 and 3 dww, respectively. Meanwhile, the soluble sugar content was constant under drought stress. These indicated that photosynthetic activity and membrane lipid integrity were quickly attenuated by drought stress in rubber tree, and osmoregulation participated in drought tolerance mechanism in rubber tree. Expressions of energy biosynthesis and ROS scavenging systems related genes, including HbCuZnSOD, HbMnSOD, HbAPX, HbCAT, HbCOA, HbATP, and HbACAT demonstrated that these genes were significantly up-regulated by drought stress, and reached a maximum at 3 dww, then followed by a decrease from 5 dww. These results suggested that drought stress adaption in rubber tree was governed by energy biosynthesis, antioxidative enzymes, and osmoregulation.
MeSH term(s)	Chlorophyll/biosynthesis ; Droughts ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Viral ; Hevea/enzymology ; Peroxidase/biosynthesis ; Plant Proteins/biosynthesis ; Reactive Oxygen Species/metabolism ; Stress, Physiological ; Superoxide Dismutase/biosynthesis
Chemical Substances	Plant Proteins ; Reactive Oxygen Species ; Chlorophyll (1406-65-1) ; Peroxidase (EC 1.11.1.7) ; Superoxide Dismutase (EC 1.15.1.1)
Language	English
Publishing date	2014-08-23
Publishing country	France
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	742978-2
ISSN	1873-2690 ; 0981-9428
ISSN (online)	1873-2690
ISSN	0981-9428
DOI	10.1016/j.plaphy.2014.08.012
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Article ; Online: Supramolecular-controlled regioselective photochemical [4 + 4] cycloaddition within Cp*Rh-based metallarectangles.

Bai, Sha / Wang, Li-Feng / Wu, Zhen-Wei / Feng, Ting / Han, Ying-Feng

Dalton transactions (Cambridge, England : 2003)

2022 Volume 51, Issue 22, Page(s) 8743–8748

Abstract: Photochemical reactions are vital synthetic means for the synthesis of natural products and highly strained molecules. However, it remains an immense challenge to control the chemo- and regioselectivity in the photoreactions of anthracene derivatives ... ...

Abstract	Photochemical reactions are vital synthetic means for the synthesis of natural products and highly strained molecules. However, it remains an immense challenge to control the chemo- and regioselectivity in the photoreactions of anthracene derivatives while maintaining high reactivity. Herein, we report the synthesis of two photoactive metallarectangles 1a and 1b by coordination-driven self-assembly of 2,6- and 2,7-bifunctionalized anthracenes with a half-sandwich rhodium template. By taking advantage of the rhodium template, the anthracene groups within the metallarectangles can be preorganized in a parallel fashion and exclusively undergo a photochemical [4 + 4] cycloaddition. As a result, the
Language	English
Publishing date	2022-06-07
Publishing country	England
Document type	Journal Article
ZDB-ID	1472887-4
ISSN	1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
ISSN (online)	1477-9234 ; 1364-5447
ISSN	0300-9246 ; 1477-9226
DOI	10.1039/d2dt01094a
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Article: HbMYB44, a Rubber Tree MYB Transcription Factor With Versatile Functions in Modulating Multiple Phytohormone Signaling and Abiotic Stress Responses.

Qin, Bi / Fan, Song-Le / Yu, Hai-Yang / Lu, Yan-Xi / Wang, Li-Feng

Frontiers in plant science

2022 Volume 13, Page(s) 893896

Abstract: The vital roles of R2R3-MYB transcription factors (TFs) in regulating stress response and phytohormone signaling have been thoroughly studied in numerous plant species, but the functions of these TFs in rubber tree are poorly understood. Rubber tree is ... ...

Abstract	The vital roles of R2R3-MYB transcription factors (TFs) in regulating stress response and phytohormone signaling have been thoroughly studied in numerous plant species, but the functions of these TFs in rubber tree are poorly understood. Rubber tree is the most important source of natural rubber but often suffers from various abiotic and biotic stresses that cause severe yield losses each year. In this study, we reported a novel
Language	English
Publishing date	2022-06-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2022.893896
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Article: Genome-wide identification and response stress expression analysis of the

Guo, Bingbing / Yang, Hong / Dai, Longjun / Zhao, Xizhu / Wang, Li-Feng

PeerJ

2022 Volume 10, Page(s) e13189

Abstract: Brassinolide (BR) plays an important role in plant growth, development, and the adaptation adversity process. Moreover, BRI1-EMS-SUPPRESSOR 1 ( ...

Abstract	Brassinolide (BR) plays an important role in plant growth, development, and the adaptation adversity process. Moreover, BRI1-EMS-SUPPRESSOR 1 (
Language	English
Publishing date	2022-05-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2703241-3
ISSN	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.13189
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Article: Veno-Arterial Extracorporeal Membrane Oxygenation in the Treatment of Hemodynamically Unstable Lupus Myocarditis: A Retrospective Case Series Study.

Shi, Yu-Jun / Wang, Li-Feng / Ma, Jun / Chen, Yi / Wang, Wei-Jun / Xie, Cui-Ying

Journal of inflammation research

2022 Volume 15, Page(s) 3761–3768

Abstract: Objective: The clinical manifestations and treatment of three patients with hemodynamically unstable lupus myocarditis (LM) were analyzed.: Methods: The clinical data of three patients with LM with hemodynamic instability, who were admitted to the ... ...

Abstract	Objective: The clinical manifestations and treatment of three patients with hemodynamically unstable lupus myocarditis (LM) were analyzed. Methods: The clinical data of three patients with LM with hemodynamic instability, who were admitted to the emergency ICU of the south hospital of the Renji Hospital, School of Medicine, Shanghai Jiao Tong University of Medicine from January 2018 to December 2021, were collected and analyzed, and relevant literatures were reviewed. Results: Two of the three patients had the first onset of systemic lupus erythematosus. The other patient had mixed connective tissue disease in the past, and lupus was the main manifestation of this disease. At the onset of the disease, all patients had chest tightness and shortness of breath; two patients had a fever, and the markers of myocardial injury increased. Cardiac color Doppler ultrasound indicated that left ventricular ejection fraction decreased significantly. Cardiac insufficiency with cardiogenic shock rapidly appeared as the main manifestation. Two patients immediately started veno-arterial extracorporeal membrane oxygenation (VA-ECMO), and ECMO was also started in one patient after a pacemaker placement was ineffective. For all three patients, high-dose hormones were given to control the primary disease, and then the ECMO machines were removed successfully. Conclusion: VA-ECMO treatment should be implemented in patients with hemodynamically unstable LM as soon as possible to maintain the patient's hemodynamics and help them overcome the crisis of cardiac dysfunction, allowing more time for primary disease treatment.
Language	English
Publishing date	2022-07-04
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2494878-0
ISSN	1178-7031
ISSN	1178-7031
DOI	10.2147/JIR.S365399
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Article ; Online: Epidemiological characteristics, virulence potential, antimicrobial resistance profiles, and phylogenetic analysis of

Song, Yang / Wang, Li-Feng / Zhou, Kuai / Liu, Shuang / Guo, Ling / Ye, Li-Yan / Gu, Jiang / Cheng, Yan / Shen, Ding-Xia

Frontiers in cellular and infection microbiology

2023 Volume 13, Page(s) 1084352

Abstract: Objective: Aeromonas caviae: Methods: A. caviae: Results: A. caviae: Conclusions: This study strengthen our understanding ... ...

Abstract	Objective: Aeromonas caviae Methods: A. caviae Results: A. caviae Conclusions: This study strengthen our understanding of
MeSH term(s)	Humans ; Aeromonas caviae ; Virulence/genetics ; Anti-Bacterial Agents/pharmacology ; Phylogeny ; Aeromonas ; Retrospective Studies ; Drug Resistance, Bacterial/genetics ; Microbial Sensitivity Tests ; beta-Lactamases/genetics ; Anti-Infective Agents
Chemical Substances	Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6) ; Anti-Infective Agents
Language	English
Publishing date	2023-02-24
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2619676-1
ISSN	2235-2988 ; 2235-2988
ISSN (online)	2235-2988
ISSN	2235-2988
DOI	10.3389/fcimb.2023.1084352
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Article ; Online: Observation on the Analgesic Effect of Different Doses of a Combination of Esketamine and Dexmedetomidine Administered for Percutaneous Endoscopic Transforaminal Discectomy: A Randomized, Double-Blind Controlled Trial.

Zhou, Jian-Shun / Chen, Zhen / Liu, Ying-Ying / Zhong, Mao-Lin / Zhong, Qiong / Wei, Jun / Hu, Qian / Wang, Jia-Sheng / Wang, Li-Feng

CNS drugs

2024

Abstract: Background: Percutaneous endoscopic transforaminal discectomy (PETD) is an effective method for treating lumbar disc herniation, and is typically performed under local anesthesia. However, inadequate analgesia during the procedure remains a concern, ... ...

Abstract	Background: Percutaneous endoscopic transforaminal discectomy (PETD) is an effective method for treating lumbar disc herniation, and is typically performed under local anesthesia. However, inadequate analgesia during the procedure remains a concern, prompting the search for a medication that can provide optimal pain control with minimal impact on the respiratory and circulatory systems. Objectives: The aim of this study was to observe the effects of different doses of esketamine combined with dexmedetomidine on reducing visual analog scale (VAS) scores during surgical interventions. Methods: One hundred two patients who underwent PETD were randomly divided into a control group (group C: normal saline + dexmedetomidine), an E1 group (0.1 mg kg Results: Compared with those in group C, the VAS scores of patients in groups E1 and E2 were lower at T Conclusion: The combination of esketamine and dexmedetomidine can reduce VAS scores during certain stages of this type of surgery; it has minimal impact on respiration and circulation. However, this approach is associated with increased incidences of postoperative dizziness and psychiatric side effects, which may also affect patients' compliance with surgical instructions from medical staff. Patient satisfaction was not greater with dexmedetomidine combined with esketamine than with dexmedetomidine alone. Trial registration: http://www.chictr.org.cn . Identifier: ChiCTR2300068206. Date of registration: 10 February 2023.
Language	English
Publishing date	2024-04-04
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	1203800-3
ISSN	1179-1934 ; 1172-7047
ISSN (online)	1179-1934
ISSN	1172-7047
DOI	10.1007/s40263-024-01083-2
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Article ; Online: Factors influencing pathological changes in the liver tissue in hepatitis B virus carriers with low-level viremia.

Fu, Haiyan / Li, Hongjuan / Du, Yingrong / Liu, Chunyun / Dang, Futao / Zhang, Xuan / Xu, Danqing / Mao, Yachao / Wang, Li Feng / Luo, Yu / Liu, Li

Clinics and research in hepatology and gastroenterology

2024 , Page(s) 102351

Abstract: Objectives: To investigate the optimal timing for initiating antiviral therapy in hepatitis B virus (HBV) carriers with low-level viremia (LLV).: Methods: We retrospectively enrolled 126 HBV carriers with LLV who underwent liver biopsy. Patients' ... ...

Abstract	Objectives: To investigate the optimal timing for initiating antiviral therapy in hepatitis B virus (HBV) carriers with low-level viremia (LLV). Methods: We retrospectively enrolled 126 HBV carriers with LLV who underwent liver biopsy. Patients' clinical data, routine blood test results, portal vein diameter, splenic vein diameter and thickness, and measurements (LSM) within 1 week before liver biopsy were obtained. Single-factor and multifactor statistical methods were used to analyze factors that affected inflammation and fibrosis in pathological liver tissues. The receiver operating characteristic curve was used to analyze liver stiffness and HBV DNA levels to determine liver tissue inflammation and fibrosis. R -Studio software was used to draw nomograms, calibration plots, and model decision curves. Results: Infection duration and HBV DNA levels affected liver tissue inflammation. Albumin(ALB), aspartate aminotransferase (AST), HBV DNA, liver stiffness, age, and splenic thickness affected liver fibrosis. The best cutoff value of the LSM for diagnosing liver inflammation and fibrosis was 7.45 (specificity, 92%). The best cutoff value of HBV DNA for diagnosing liver inflammation and fibrosis was 39.5 (specificity, 96%). HBV DNA,and splenic thickness affected the treatment decision in naive chronic hepatitis Bpatients with LLV CONCLUSIONS: HBV carriers with LLV have high incidences of liver tissue inflammation and fibrosis. The infection duration and HBV DNA levels affected liver inflammation whereas the ALB, AST AST levels, HBV DNA, LSM, age, and splenic thickness affected liver fibrosis. Eligible expansion of antiviral treatment indications is necessary, however, a universal treatment approach may be inefficient. HBV DNA can be a reference for initiating antiviral therapy.
Language	English
Publishing date	2024-05-03
Publishing country	France
Document type	Journal Article
ZDB-ID	2594333-9
ISSN	2210-741X ; 2210-7401
ISSN (online)	2210-741X
ISSN	2210-7401
DOI	10.1016/j.clinre.2024.102351
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