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  1. Article ; Online: Embedded Spatial-Temporal Convolutional Neural Network Based on Scattered Light Signals for Fire and Interferential Aerosol Classification.

    Xu, Fang / Zhu, Ming / Lin, Mengxue / Wang, Maosen / Chen, Lei

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 3

    Abstract: Photoelectric smoke detectors are the most cost-effective devices for very early warning fire alarms. However, due to the different light intensity response values of different kinds of fire smoke and interference from interferential aerosols, they have ... ...

    Abstract Photoelectric smoke detectors are the most cost-effective devices for very early warning fire alarms. However, due to the different light intensity response values of different kinds of fire smoke and interference from interferential aerosols, they have a high false-alarm rate, which limits their popularity in Chinese homes. To address these issues, an embedded spatial-temporal convolutional neural network (EST-CNN) model is proposed for real fire smoke identification and aerosol (fire smoke and interferential aerosols) classification. The EST-CNN consists of three modules, including information fusion, scattering feature extraction, and aerosol classification. Moreover, a two-dimensional spatial-temporal scattering (2D-TS) matrix is designed to fuse the scattered light intensities in different channels and adjacent time slices, which is the output of the information fusion module and the input for the scattering feature extraction module. The EST-CNN is trained and tested with experimental data measured on an established fire test platform using the developed dual-wavelength dual-angle photoelectric smoke detector. The optimal network parameters were selected through extensive experiments, resulting in an average classification accuracy of 98.96% for different aerosols, with only 67 kB network parameters. The experimental results demonstrate the feasibility of installing the designed EST-CNN model directly in existing commercial photoelectric smoke detectors to realize aerosol classification.
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24030778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: High-efficiency and low-hazard artillery recoil reduction technology based on barrel gas reflection.

    He, Fu / Dai, Jinsong / Lin, Shengye / Wang, Maosen / Su, Xiaopeng

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 7497

    Abstract: Reducing recoil as well as reducing muzzle hazards are important issues in artillery design. This paper presents a barrel gas reflection method for the artillery aiming for efficient recoil reduction while reducing muzzle hazards. The launching process ... ...

    Abstract Reducing recoil as well as reducing muzzle hazards are important issues in artillery design. This paper presents a barrel gas reflection method for the artillery aiming for efficient recoil reduction while reducing muzzle hazards. The launching process is modeled by coupling the interior ballistic equations and the flow equations of the barrel gas reflection device. The fourth-order Runge-Kutta method was used to solve the model, and the LHS method as well as the Kriging model was used to establish a mapping relationship between the parameters and the effect. To validate the proposed model, shooting experiments are carried out on a 30 mm caliber artillery. The maximum error between the experiment and simulation results was 5.32%. The experiment has demonstrated that the barrel gas reflection method increases the recoil reduction efficiency of artillery by 44.54% and reduces the muzzle hazard by 52.18%. Finally, the barrel gas reflection method can produce effects with the muzzle device at the same time, and it has little effect on the velocity of the projectile muzzle velocity, and it provides a new way of thinking for the development of future artillery recoil reduction technology.
    Language English
    Publishing date 2024-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-58313-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Complete genome sequence of polygonatum kingianum mottle virus infecting Polygonatum kingianum Coll. et Hemsl in Yunnan, China.

    Wang, Maosen / Su, Xiaoxia / Zhang, Fan / Wang, Tiantian / Zheng, Kuanyu / Zhang, Zhongkai

    Archives of virology

    2024  Volume 169, Issue 2, Page(s) 39

    Abstract: The complete genome sequence of a putative novel potyvirus, tentatively named "polygonatum kingianum mottle virus" (PKgMV; GenBank accession no. ON428226), infecting Polygonatum kingianum in China, was obtained by next-generation sequencing (NGS), ... ...

    Abstract The complete genome sequence of a putative novel potyvirus, tentatively named "polygonatum kingianum mottle virus" (PKgMV; GenBank accession no. ON428226), infecting Polygonatum kingianum in China, was obtained by next-generation sequencing (NGS), reverse transcription polymerase chain reaction (RT-PCR), and rapid amplification of cDNA ends (RACE). PKgMV exhibits the typical genome organization and characteristics of members of the genus Potyvirus, with a length of 10,002 nucleotides (nt) and a large open reading frame (nt 108 to 9,746) encoding a polyprotein of 3,212 amino acids (aa) (363.68 kDa). Pairwise comparisons revealed that the PKgMV polyprotein shares 50.5-68.6% nt and 43.1-72.2% aa sequence identity with reported members of the genus Potyvirus. Moreover, phylogenetic analysis indicated that PKgMV is closely related to polygonatum kingianum virus 1 (PKgV1; accession no. MK427056). These results suggest that the PKgMV is a novel member of the genus Potyvirus of the family Potyviridae.
    MeSH term(s) China ; Phylogeny ; Polygonatum ; Amino Acids ; Nucleotides ; Polyproteins ; Potyvirus/genetics
    Chemical Substances Amino Acids ; Nucleotides ; Polyproteins
    Language English
    Publishing date 2024-02-01
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-024-05965-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Stability Control of Quadruped Robot Based on Active State Adjustment.

    Gu, Sai / Meng, Fei / Liu, Botao / Zhang, Zhihao / Sun, Nengxiang / Wang, Maosen

    Biomimetics (Basel, Switzerland)

    2023  Volume 8, Issue 1

    Abstract: The quadruped robot has a strong motion performance and broad application prospects in practical applications. However, during the movement of the quadruped robot, it is easy to be affected by external disturbance and environmental changes, which makes ... ...

    Abstract The quadruped robot has a strong motion performance and broad application prospects in practical applications. However, during the movement of the quadruped robot, it is easy to be affected by external disturbance and environmental changes, which makes it unable to achieve the ideal effect movement. Therefore, it is very important for the quadruped robot to adjust actively according to its own state detection. This paper proposes an active state adjustment control method based on its own state, which can realize disturbance recovery and active environment adaptation. Firstly, the controller is designed according to the physical model of the quadruped robot, and the foot forces are optimized using the quadratic program (QP) method. Then, the disturbance compensation method based on dynamic analysis is studied and combined with the controller itself. At the same time, according to the law of biological movement, the movement process of the quadruped robot is actively adjusted according to the different movement environment, so that it can adapt to various complex environments. Finally, it is verified in a simulation environment and quadruped robot prototype. The results show that the quadruped robot has a strong active disturbance recovery ability and active environment adaptability.
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2313-7673
    ISSN (online) 2313-7673
    DOI 10.3390/biomimetics8010112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nanoarchitectonics of cellulose nanocrystal conjugated with a tetrasaccharide-glycoprobe for targeting oligodendrocyte precursor cells.

    Tang, Xiaoli / Wang, Zhuqun / Wang, Maosen / Zhou, Shuyu / Chen, Jinghua / Xu, Shuqin

    Carbohydrate polymers

    2023  Volume 317, Page(s) 121086

    Abstract: Demyelination is a serious complication of neurological disorders, which can be reversed by oligodendrocyte precursor cell (OPC) as the available source of myelination. Chondroitin sulfate (CS) plays key roles in neurological disorders, which still ... ...

    Abstract Demyelination is a serious complication of neurological disorders, which can be reversed by oligodendrocyte precursor cell (OPC) as the available source of myelination. Chondroitin sulfate (CS) plays key roles in neurological disorders, which still attracted less attention on how CS modulates the fate of OPCs. Nanoparticle coupled with glycoprobe is a potential strategy for investigating the carbohydrate-protein interaction. However, there is lack of CS-based glycoprobe with enough chain length that interact with protein effectively. Herein, we designed a responsive delivery system, in which CS was the target molecule, and cellulose nanocrystal (CNC) was the penetrative nanocarrier. A coumarin derivative (B) was conjugated at the reducing end of an unanimal-sourced chondroitin tetrasaccharide (4mer). This glycoprobe (4B) was grafted to the surface of a rod-like nanocarrier, which had a crystalline core and a poly(ethylene glycol) shell. This glycosylated nanoparticle (N4B-P) displayed a uniform size, improved water-solubility, and responsive release of glycoprobe. N4B-P displayed strong green fluorescence and good cell-compatibility, which imaged well the neural cells including astrocytes and OPCs. Interestingly, both of glycoprobe and N4B-P were internalized selectively by OPCs when they were incubated in astrocytes/OPCs mixtures. This rod-like nanoparticle would be a potential probe for studying carbohydrate-protein interaction in OPCs.
    MeSH term(s) Oligodendrocyte Precursor Cells ; Oligodendroglia/metabolism ; Cell Differentiation ; Cellulose/pharmacology ; Cellulose/metabolism ; Chondroitin Sulfates/metabolism ; Nanoparticles
    Chemical Substances Cellulose (9004-34-6) ; Chondroitin Sulfates (9007-28-7)
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2023.121086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Genomic characterization and seed transmission of a novel unclassified partitivirus infecting Polygonatum kingianum Coll. et Hemsl

    Zhang, Fan / Su, Xiaoxia / Zhang, Shaozhi / Wang, Maosen / Wang, Tiantian / Zheng, Xue / Wu, Kuo / Zheng, Kuanyu / Zhang, Zhongkai

    Heliyon. 2023 May 26, p.e16719-

    2023  

    Abstract: This study identified a novel virus in the family Partitiviridae infecting Polygonatum kingianum Coll. et Hemsl, which is tentatively named polygonatum kingianum cryptic virus 1 (PKCV1). PKCV1 genome has two RNA segments: dsRNA1 (1926 bp) has an open ... ...

    Abstract This study identified a novel virus in the family Partitiviridae infecting Polygonatum kingianum Coll. et Hemsl, which is tentatively named polygonatum kingianum cryptic virus 1 (PKCV1). PKCV1 genome has two RNA segments: dsRNA1 (1926 bp) has an open reading frame (ORF) encoding an RNA-dependent RNA polymerase (RdRp) of 581 amino acids (aa), and dsRNA2 (1721 bp) has an ORF encoding a capsid protein (CP) of 495 aa. The RdRp of PKCV1 shares 20.70-82.50% aa identity with known partitiviruses, and the CP of PKCV1 shares 10.70-70.80% aa identity with known partitiviruses. Moreover, PKCV1 phylogenetically clustered with unclassified members of the Partitiviridae family. Additionally, PKCV1 is common in P. kingianum planting regions and has a high infection rate in P. kingianum seeds.
    Keywords Partitiviridae ; Polygonatum ; RNA ; RNA-directed RNA polymerase ; coat proteins ; genome ; genomics ; phylogeny ; viruses ; Polygonatum kingianum ; RdRp ; CP ; Seed transmission
    Language English
    Dates of publication 2023-0526
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version ; Use and reproduction
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e16719
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Sodium alginate as an eco-friendly rheology modifier and salt-tolerant fluid loss additive in water-based drilling fluids.

    Wei, Zhaojie / Wang, Maosen / Li, Ying / An, Yinghui / Li, Kaijun / Bo, Kun / Guo, Mingyi

    RSC advances

    2022  Volume 12, Issue 46, Page(s) 29852–29864

    Abstract: The rheological and filtration performance of drilling fluids greatly depends on the additives used. To address the negative impact on the drilling fluid performance stemming from electrolyte contamination, a sustainable sodium alginate (SA) biopolymer ... ...

    Abstract The rheological and filtration performance of drilling fluids greatly depends on the additives used. To address the negative impact on the drilling fluid performance stemming from electrolyte contamination, a sustainable sodium alginate (SA) biopolymer was employed as an additive in water-based drilling fluids to overcome the performance deterioration caused by the polyelectrolyte effect under salt contamination. The results demonstrated that SA performs better than sodium carboxymethyl cellulose (Na-CMC) and polyanionic cellulose (PAC-LV), the widely used drilling fluid additives. Although exposed to highly concentrated salt contamination, the addition of SA can mitigate viscosity variation and maintain a lower filtration volume of a base fluid (BF), whereas an advanced variation in CMC/BF and PAC/BF was observed. The possible rheology and filtration mechanism of SA under highly concentrated salt contamination were investigated through zeta potential, particle size distribution, and scanning electron microscopy (SEM). The results revealed that the anchoring groups on the SA molecular chain enable them to strongly adsorb on the negatively charged bentonite surface
    Language English
    Publishing date 2022-10-19
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d2ra04448j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Clinical implications of RAB13 expression in pan-cancer based on multi-databases integrative analysis.

    Zhang, Xu-Dong / Liu, Zhong-Yuan / Luo, Kai / Wang, Xiang-Kun / Wang, Mao-Sen / Huang, Shuai / Li, Ren-Feng

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 16859

    Abstract: Worldwide, cancer is a huge burden, and each year sees an increase in its incidence. RAB (Ras-related in brain) 13 is crucial for a number of tumor types. But more research on RAB13's tumor-related mechanism is still required. This study's goal was to ... ...

    Abstract Worldwide, cancer is a huge burden, and each year sees an increase in its incidence. RAB (Ras-related in brain) 13 is crucial for a number of tumor types. But more research on RAB13's tumor-related mechanism is still required. This study's goal was to investigate RAB13's function in human pan-cancer, and we have also preliminarily explored the relevant mechanisms. To investigate the differential expression, survival prognosis, immunological checkpoints, and pathological stage of RAB13 in human pan-cancer, respectively, databases of TIMER2.0, GEPIA 2, and UALCAN were employed. CBioPortal database was used to analyze the mutation level, meanwhile, PPI network was constructed based on STRING website. The putative functions of RAB13 in immunological infiltration were investigated using single sample gene set enrichment analysis (ssGSEA). The mechanism of RAB13 in hepatocellular cancer was also briefly investigated by us using gene set enrichment analysis (GSEA). RAB13 was differentially expressed in a number of different cancers, including liver hepatocellular carcinoma (LIHC), stomach adenocarcinoma (STAD), etc. Additionally, RAB13 overexpression in LGG and LIHC is associated with a worse prognosis, including overall survival (OS) and disease-free survival (DFS). Then, we observed that early in BLCA, BRAC, CHOL, ESCA, HNSC, KICH, KIRC, LIHC, LUAD, LUSC, and STAD, the level of RAB13 expression was raised. Next, we found that "amplification" was the most common mutation in RAB13. The expression of SLC39A1, JTB, SSR2, SNAPIN, and RHOC was strongly positively linked with RAB13, according to a correlation study. RAB13 favorably regulated B cell, CD8 + T cell, CD4 + T cell, macrophage, neutrophil, and dendritic cell in LIHC, according to immune infiltration analysis. Immune checkpoint study revealed a positive correlation between RAB13 expression and PD1, PDL1, and CTLA4 in LIHC. According to GSEA, RAB13 is involved in a number of processes in LIHC, including MTORC1 signaling, MYC targets v1, G2M checkpoint, MITOTIC spindle, DNA repair, P53 pathway, glycolysis, PI3K-AKT-MTOR signaling, etc. RAB13 is a possible therapeutic target in LIHC and can be used as a prognostic marker.
    MeSH term(s) Humans ; Phosphatidylinositol 3-Kinases ; Carcinoma, Hepatocellular/genetics ; Adenocarcinoma ; Liver Neoplasms ; Stomach Neoplasms ; rab GTP-Binding Proteins/genetics
    Chemical Substances Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; RAB13 protein, human (EC 3.6.1.-) ; rab GTP-Binding Proteins (EC 3.6.5.2)
    Language English
    Publishing date 2023-10-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-43699-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Genomic characterization and seed transmission of a novel unclassified partitivirus infecting

    Zhang, Fan / Su, Xiaoxia / Zhang, Shaozhi / Wang, Maosen / Wang, Tiantian / Zheng, Xue / Wu, Kuo / Zheng, Kuanyu / Zhang, Zhongkai

    Heliyon

    2023  Volume 9, Issue 6, Page(s) e16719

    Abstract: This study identified a novel virus in the ... ...

    Abstract This study identified a novel virus in the family
    Language English
    Publishing date 2023-05-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e16719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Mechanisms and regulations of ferroptosis.

    Zhang, Xu-Dong / Liu, Zhong-Yuan / Wang, Mao-Sen / Guo, Yu-Xiang / Wang, Xiang-Kun / Luo, Kai / Huang, Shuai / Li, Ren-Feng

    Frontiers in immunology

    2023  Volume 14, Page(s) 1269451

    Abstract: Regulation of cell mortality for disease treatment has been the focus of research. Ferroptosis is an iron-dependent regulated cell death whose mechanism has been extensively studied since its discovery. A large number of studies have shown that ... ...

    Abstract Regulation of cell mortality for disease treatment has been the focus of research. Ferroptosis is an iron-dependent regulated cell death whose mechanism has been extensively studied since its discovery. A large number of studies have shown that regulation of ferroptosis brings new strategies for the treatment of various benign and malignant diseases. Iron excess and lipid peroxidation are its primary metabolic features. Therefore, genes involved in iron metabolism and lipid metabolism can regulate iron overload and lipid peroxidation through direct or indirect pathways, thereby regulating ferroptosis. In addition, glutathione (GSH) is the body's primary non-enzymatic antioxidants and plays a pivotal role in the struggle against lipid peroxidation. GSH functions as an auxiliary substance for glutathione peroxidase 4 (GPX4) to convert toxic lipid peroxides to their corresponding alcohols. Here, we reviewed the researches on the mechanism of ferroptosis in recent years, and comprehensively analyzed the mechanism and regulatory process of ferroptosis from iron metabolism and lipid metabolism, and then described in detail the metabolism of GPX4 and the main non-enzymatic antioxidant GSH
    MeSH term(s) Humans ; Ferroptosis ; Phospholipid Hydroperoxide Glutathione Peroxidase/metabolism ; Iron/metabolism ; Glutathione Peroxidase/metabolism ; Lipid Peroxidation/physiology ; Antioxidants/metabolism ; Glutathione/metabolism ; Iron Overload
    Chemical Substances Phospholipid Hydroperoxide Glutathione Peroxidase (EC 1.11.1.12) ; Iron (E1UOL152H7) ; Glutathione Peroxidase (EC 1.11.1.9) ; Antioxidants ; Glutathione (GAN16C9B8O)
    Language English
    Publishing date 2023-10-06
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1269451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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