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Article ; Online: Reconstructed magnetic resonance image-based effusion volume assessment for temporomandibular joint arthralgia.

Xu, Jiali / Wang, Dongmei / Yang, Chunhua / Wang, Fangfang / Wang, Meiqing

2023 Volume 50, Issue 11, Page(s) 1202–1210

Abstract: Background: Joint effusion is often noticed in magnetic resonance image (MRI) and its diagnostic value for arthralgia of the temporomandibular joint (TMJ) remains obscure.: Objective: To develop a method for quantitatively evaluating the joint ... ...

Abstract	Background: Joint effusion is often noticed in magnetic resonance image (MRI) and its diagnostic value for arthralgia of the temporomandibular joint (TMJ) remains obscure. Objective: To develop a method for quantitatively evaluating the joint effusion revealed in MRI and its diagnostic value for arthralgia of the TMJ. Methods: Two-hundreds and twenty-eight TMJs, 101 with arthralgia (Group P) and 105 without (Group NP) from 103 patients, and 22 TMJs (Group CON) from 11 asymptomatic volunteers were examined by using MRI. The effusion volume was measured after constructing a three-dimensional structure of the joint effusion revealed in MRI by using the ITK-SNAP software. The diagnostic capabilities of the effusion volume on arthralgia were evaluated with receiver operating characteristic (ROC) curve analysis. Results: Totally 146 joints showed MRI signs of joint effusion, including nine joints from Group CON. However, the medium volume was greater in Group P (66.65 mm Conclusion: The present method for evaluate joint effusion volume well discriminated painful TMJs from non-pain ones.
Language	English
Publishing date	2023-08-02
Publishing country	England
Document type	Journal Article
ZDB-ID	187079-8
ISSN	1365-2842 ; 0305-182X
ISSN (online)	1365-2842
ISSN	0305-182X
DOI	10.1111/joor.13551
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Zs.A 991: Show issues

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Article ; Online: Automatic detection of locomotor play in young pigs: A proof of concept

Larsen, Mona L.V. / Wang, Meiqing / Willems, Sam / Liu, Dong / Norton, Tomas

IAgrE Biosystems Engineering. 2023 May, v. 229 p.154-166

2023

Abstract: Play behaviour is considered an indicator of animal welfare in young pigs. However, as play behaviour events are short-lasting and occur sporadically, continuous monitoring is necessary. This study presents a first attempt at automatic detection of ... ...

Abstract	Play behaviour is considered an indicator of animal welfare in young pigs. However, as play behaviour events are short-lasting and occur sporadically, continuous monitoring is necessary. This study presents a first attempt at automatic detection of locomotor play behaviour in young pigs from video by classifying locomotor play from other solitary behaviours including standing, walking, and running. Two methods were developed, compared, and sequentially combined: (1) a less computational heavy method utilising the Gaussian Mixture Model for quantification of movement combined with the calculation of contour features and standard machine learning classifiers (FEATURES); (2) a computational heavy method utilising a deep learning classifier taking both spatial and temporal features into account (DEEP). The DEEP classifier outperformed the FEATURES classifier and obtained values of internal validation recall, precision, and specificity of 94%, 88% and 96%, respectively. When combining the two classification methods, almost similar performance was retained, whilst 44% of the other behaviours were correctly classified without the need for deep learning methods. The combination thereby decreased the computational power needed to run the algorithm. Thus, locomotor play can be automatically detected in young pigs and the combination of a less computational heavy method with a deep learning method can reduce the computational requirements for the classification and detection of complex behaviours. Future work should focus on the segmentation of single pigs during high-speed activity in order to enable the play detection algorithm to work in real-life settings.
Keywords	algorithms ; animal welfare ; automatic detection ; models ; Technology ; Precision Livestock Farming ; Computer vision ; Gaussian Mixture Model ; Animal behaviour
Language	English
Dates of publication	2023-05
Size	p. 154-166.
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	2075942-3
ISSN	1537-5110
ISSN	1537-5110
DOI	10.1016/j.biosystemseng.2023.03.006
Database	NAL-Catalogue (AGRICOLA)

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Z 1110: Show issues

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Article ; Online: Binary Logistic Regression Analysis on the Association of Occlusion with the Temporomandibular Joint Arthralgia in the Partial Denture Wearers-A Retrospective Study.

Song, Lixing / Zhang, Zhenping / Wang, Cuicui / Yu, Jia / Liu, Lu / Wang, Meiqing

The International journal of prosthodontics

2023 Volume 36, Issue 6, Page(s) 154–167

Abstract: Purpose: To analyze the potential association between the occlusion features and the incidence of temporomandibular joint (TMJ) arthralgia in patients with partial dentures.: Materials and methods: A total of 101 partial denture wearers were ... ...

Abstract	Purpose: To analyze the potential association between the occlusion features and the incidence of temporomandibular joint (TMJ) arthralgia in patients with partial dentures. Materials and methods: A total of 101 partial denture wearers were collected, 45 with unilateral TMJ arthralgia diagnosed according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Binary logistic regression analysis was adopted. The TMJ asymptomatic group (n = 45) was quantified as 0, while the TMJ arthralgia group (n = 56) was quantified as 1. In total, 13 occlusion variables were analyzed: gender, age, number of prosthetic teeth, number of dentition quadrants with a prosthetic tooth, anterior or posterior prosthesis location in maxillary or mandibular dentition, occluded prosthesis pair, anterior overjet, and overbite relation. Simple and multiple binary logistic models were adopted, accordingly, for the risk impact of them on TMJ arthralgia. Results: Overbite (OR = 2.238) and maxillary anterior prosthesis (OR = 0.305) were entered into the simple binary logistic model; while overbite (OR = 2.774) plus maxillary anterior prosthesis (OR = 0.347), overbite (OR = 3.425) plus unilateral maxillary posterior prosthesis (OR = 4.672), and overbite (OR = 3.476) plus overjet (OR = 0.436) and mandibular anterior prosthesis (OR = 0.177) were entered into the multivariate logistic regression model (all, P < .05). Conclusions: Partial denture wearers with a deep overbite, especially those with a unilateral maxillary posterior prosthesis, had a higher prevalence of unilateral TMJ arthralgia.
MeSH term(s)	Humans ; Logistic Models ; Retrospective Studies ; Overbite ; Temporomandibular Joint ; Arthralgia/etiology ; Denture, Partial
Language	English
Publishing date	2023-12-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	645046-5
ISSN	1942-4426 ; 0893-2174
ISSN (online)	1942-4426
ISSN	0893-2174
DOI	10.11607/ijp.8118
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Zs.A 2430: Show issues

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Article ; Online: Inverted U-shaped relationship between sleep duration and phenotypic age in US adults: a population-based study.

You, Yanwei / Chen, Yuquan / Liu, Ruidong / Zhang, Yangchang / Wang, Meiqing / Yang, Zihao / Liu, Jianxiu / Ma, Xindong

Scientific reports

2024 Volume 14, Issue 1, Page(s) 6247

Abstract: Sleep is a modifiable behavior that can be targeted in interventions aimed at promoting healthy aging. This study aims to (i) identify the sleep duration trend in US adults; (ii) investigate the relationship between sleep duration and phenotypic age; and ...

Abstract	Sleep is a modifiable behavior that can be targeted in interventions aimed at promoting healthy aging. This study aims to (i) identify the sleep duration trend in US adults; (ii) investigate the relationship between sleep duration and phenotypic age; and (iii) explore the role of exercise in this relationship. Phenotypic age as a novel index was calculated according to biomarkers collected from US adults based on the National Health and Nutrition Examination Survey (NHANES). Sleep information was self-reported by participants and discerned through individual interviews. The principal analytical method employed was weighted multivariable linear regression modeling, which accommodated for the complex multi-stage sampling design. The potential non-linear relationship was explored using a restricted cubic spline (RCS) model. Furthermore, subgroup analyses evaluated the potential effects of sociodemographic and lifestyle factors on the primary study outcomes. A total of 13,569 participants were finally included in, thereby resulting in a weighted population of 78,880,615. An examination of the temporal trends in sleep duration revealed a declining proportion of individuals with insufficient and markedly deficient sleep time since the 2015-2016 cycle. Taken normal sleep group as a reference, participants with extreme short sleep [β (95% CI) 0.582 (0.018, 1.146), p = 0.044] and long sleep [β (95% CI) 0.694 (0.186, 1.203), p = 0.010] were both positively associated with phenotypic age using the fully adjusted model. According to the dose-response relationship between sleep duration and phenotypic age, long sleep duration can benefit from regular exercise activity, whereas short sleep duration with more exercise tended to have higher phenotypic age. There is an inverted U-shaped relationship between short and long sleep durations and phenotypic age. This study represents an important step forward in our understanding of the complex relationship between sleep and healthy aging. By shedding light on this topic and providing practical exercise recommendations for promoting healthy sleep habits, researchers can help individuals live longer, healthier, and more fulfilling lives.
MeSH term(s)	Adult ; Humans ; Nutrition Surveys ; Sleep Duration ; Cross-Sectional Studies ; Sleep/physiology ; Risk Factors ; Sleep Wake Disorders
Language	English
Publishing date	2024-03-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-56316-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: miR-708-5p deficiency involves the degeneration of mandibular condylar chondrocytes via the TLR4/NF-κB pathway.

Xu, Lingfeng / Zhang, Yuejiao / Yu, Jia / Huo, Wanqiu / Xu, Jiali / Yang, Hongxu / Zhang, Mian / Yu, Shibing / Wu, Yaoping / Wang, Meiqing

Osteoarthritis and cartilage

2024

Abstract: Objective: Ageing and aberrant biomechanical stimulation are two major risk factors for osteoarthritis (OA). One of the main characteristics of aged cartilage is cellular senescence. One of the main characteristics of osteoarthritic joints is cartilage ... ...

Abstract	Objective: Ageing and aberrant biomechanical stimulation are two major risk factors for osteoarthritis (OA). One of the main characteristics of aged cartilage is cellular senescence. One of the main characteristics of osteoarthritic joints is cartilage degeneration. The cells in the temporomandibular joint (TMJ) cartilage are zonally arranged. The deep zone cells are differentiated from the superficial zone cells (SZCs). The purpose of the present study was to investigate whether degenerative shear stress (SS) stimulates the senescence programme in TMJ SZCs, and to determine which miRNA is involved in this process. Method: SZCs were isolated from the TMJ condyles of 3-week-old rats and treated with continuous passaging or SS. RNA sequencing was conducted to identify miRNA(s) that overlap with those involved in the replication senescence process and the SS-induced degeneration programme. Unilateral anterior crossbite (UAC), which is TMJ-OA inducible, was applied to 2-month-old and 12-month-old mice for 3 weeks. The effect of TMJ local injection of agomiR-708-5p was evaluated histologically. Results: Both replication and SS treatment induced SZC senescence. miR-708-5p was identified. Knocking down miR-708-5p in SS-treated SZCs led to more severe senescence by alleviating the inhibitory impact of miR-708-5p on the TLR4/NF-κB pathway. miR-708-5p expression in mouse TMJ cartilage decreased with age. UAC induced more severe osteoarthritic cartilage lesions in 12-month-old mice than in 2-month-old mice. Injection of agomiR-708-5p suppressed UAC-induced osteoarthritic cartilage lesions. Conclusions: Age-related miR-708-5p deficiency is involved in the mechanically stimulated OA process. Intra-articular administration of agomiR-708-5p is a promising new strategy for OA treatment.
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1167809-4
ISSN	1522-9653 ; 1063-4584
ISSN (online)	1522-9653
ISSN	1063-4584
DOI	10.1016/j.joca.2024.02.007
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Zs.A 3828: Show issues

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Book ; Online: Chi-square Loss for Softmax

Wang, Zeyu / Wang, Meiqing

an Echo of Neural Network Structure

2021

Abstract: Softmax working with cross-entropy is widely used in classification, which evaluates the similarity between two discrete distribution columns (predictions and true labels). Inspired by chi-square test, we designed a new loss function called chi-square ... ...

Abstract	Softmax working with cross-entropy is widely used in classification, which evaluates the similarity between two discrete distribution columns (predictions and true labels). Inspired by chi-square test, we designed a new loss function called chi-square loss, which is also works for Softmax. Chi-square loss has a statistical background. We proved that it is unbiased in optimization, and clarified its using conditions (its formula determines that it must work with label smoothing). In addition, we studied the sample distribution of this loss function by visualization and found that the distribution is related to the neural network structure, which is distinct compared to cross-entropy. In the past, the influence of structure was often ignored when visualizing. Chi-square loss can notice changes in neural network structure because it is very strict, and we explained the reason for this strictness. We also studied the influence of label smoothing and discussed the relationship between label smoothing and training accuracy and stability. Since the chi-square loss is very strict, the performance will degrade when dealing samples of very many classes.
Keywords	Computer Science - Machine Learning ; Computer Science - Artificial Intelligence
Subject code	006
Publishing date	2021-08-31
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: [Occlusal contact principles in prosthodontics].

Wang, Meiqing

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2012 Volume 30, Issue 6, Page(s) 557–561

Abstract: The occlusion contact, which is engaged in many dental clinical scopes, is the primary subject in the field of dental occlusion. Prosthodontics is one of the fields that are involved in with this subject, including the static relation (the occlusal ... ...

Abstract	The occlusion contact, which is engaged in many dental clinical scopes, is the primary subject in the field of dental occlusion. Prosthodontics is one of the fields that are involved in with this subject, including the static relation (the occlusal contacts in intercuspal occlusion) and the dynamic relation (such as that in chewing movement). Not only the restorations, but also the abutments, that have to be properly managed to obtain a harmony occlusal contact relationship.
MeSH term(s)	Dental Occlusion ; Humans ; Mastication ; Prosthodontics ; Tooth
Language	Chinese
Publishing date	2012-12
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1202342-5
ISSN	1000-1182
ISSN	1000-1182
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Zs.A 4073: Show issues

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Article ; Online: Development of a biomechanical model for dynamic occlusal stress analysis.

Duanmu, Zheng / Liu, Lu / Deng, Qi / Ren, Yuanyuan / Wang, Meiqing

International journal of oral science

2021 Volume 13, Issue 1, Page(s) 29

Abstract: The use of traditional finite element method (FEM) in occlusal stress analysis is limited due to the complexity of musculature simulation. The present purpose was to develop a displacement boundary condition (DBC)-FEM, which evaded the muscle factor, to ... ...

Abstract	The use of traditional finite element method (FEM) in occlusal stress analysis is limited due to the complexity of musculature simulation. The present purpose was to develop a displacement boundary condition (DBC)-FEM, which evaded the muscle factor, to predict the dynamic occlusal stress. The geometry of the DBC-FEM was developed based on the scanned plastic casts obtained from a volunteer. The electrognathographic and video recorded jaw positional messages were adopted to analyze the dynamic occlusal stress. The volunteer exhibited asymmetrical lateral movements, so that the occlusal stress was further analyzed by using the parameters obtained from the right-side eccentric movement, which was 6.9 mm long, in the stress task of the left-side eccentric movement, which was 4.1 mm long. Further, virtual occlusion modification was performed by using the carving tool software aiming to improve the occlusal morphology at the loading sites. T-Scan Occlusal System was used as a control of the in vivo detection for the location and strength of the occlusal contacts. Data obtained from the calculation using the present developed DBC-FEM indicated that the stress distribution on the dental surface changed dynamically with the occlusal contacts. Consistent with the T-Scan recordings, the right-side molars always showed contacts and higher levels of stress. Replacing the left-side eccentric movement trace by the right-side one enhanced the simulated stress on the right-side molars while modification of the right-side molars reduced the simulated stress. The present DBC-FEM offers a creative approach for pragmatic occlusion stress prediction.
Language	English
Publishing date	2021-09-08
Publishing country	India
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2569849-7
ISSN	2049-3169 ; 1674-2818
ISSN (online)	2049-3169
ISSN	1674-2818
DOI	10.1038/s41368-021-00133-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Determination of the complete mitochondrial genome of

Wang, Mei-Qing / Yao, Run / Jiang, Feng / Zhan, Xiao-Dong

Mitochondrial DNA. Part B, Resources

2021 Volume 6, Issue 11, Page(s) 3222–3223

Abstract: The mitochondrial genome ... ...

Abstract	The mitochondrial genome of
Language	English
Publishing date	2021-10-15
Publishing country	England
Document type	Journal Article
ISSN	2380-2359
ISSN (online)	2380-2359
DOI	10.1080/23802359.2021.1990147
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Application to science of occlusion in occlusal reconstruction

WANG Mei-qing / XIONG Wei

口腔疾病防治, Vol 24, Iss 10, Pp 501-

2016 Volume 506

Abstract: The core issues of the subject of occlusion is the occlusal contact relationship of the maxillary and mandibular dentitions, and also the mandibular position. Occlusion reconstruction is a kind of treatments aiming to the rehabilitate the dental contact ... ...

Abstract	The core issues of the subject of occlusion is the occlusal contact relationship of the maxillary and mandibular dentitions, and also the mandibular position. Occlusion reconstruction is a kind of treatments aiming to the rehabilitate the dental contact relationship at the appropriate mandibular position by means of prosthetic methods. Its indications focused on the patients who have quite a lot of natural teeth but lose the stable occlusal contact condition that requires a reestablishment. The periodontal feedback mechanism of the remained natural teeth exposes the occlusion under reconstruction to an environment with active and complex moderation of the neuromuscular adjustment that requires a higher level of the patients’ adaptation. In this article, we will focus on the topics of the mandibular position and occlusion contact features, which are obtaining the accurate mandibular position and establishing a stable contact relation. The former is the base and the latter is the target of occlusion reconstruction.
Keywords	Occlusion reconstruction， ; Mandibular position， ; Science of occlusion， ; Occlusion， ; Dental prosthesis， ; Medicine ; R
Language	Chinese
Publishing date	2016-10-01T00:00:00Z
Publisher	Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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