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  1. Article ; Online: How does government environmental investment promote green development: Evidence from China.

    Wang, Qin / Zhou, Chao

    PloS one

    2023  Volume 18, Issue 10, Page(s) e0292223

    Abstract: The 14th Five-Year Plan stated that China should accelerate green development and promote a comprehensive green transition in economic and social development. As China's economic growth slows, green development becomes greatly significant for the high- ... ...

    Abstract The 14th Five-Year Plan stated that China should accelerate green development and promote a comprehensive green transition in economic and social development. As China's economic growth slows, green development becomes greatly significant for the high-quality development of the economy. Based on China's provincial panel data from 2005 to 2021, this study applies fixed effects model and mediating effect model to explore the influence of the government environmental investment on green development. The results indicate that (1) the government environmental investment was conducive to green development, but such effect weakened with time. (2) The government environmental investment indirectly promoted green development through the application of green patents and economic agglomeration. (3) The promotional effect of the government environmental investment varied according to region and time. Specifically, investment exerted the most significant effect on the green development of eastern China, which became more evident after 2015. The government should promote green development by implementing long-term assessment and accountability mechanisms, expanding the scale of economic agglomeration, improving the efficiency of the application of green patents, and improving the accuracy of environmental investment.
    MeSH term(s) Investments ; China ; Economic Development ; Government ; Social Change
    Language English
    Publishing date 2023-10-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0292223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Effect of the characteristic town policy on sewage treatment in mountainous areas: Evidence from Chongqing.

    Zhou, Chao / Wang, Qin

    Heliyon

    2023  Volume 9, Issue 12, Page(s) e22830

    Abstract: The report to the 20th National Congress of the Communist Party of China highlighted the necessity of advancing a new type of urbanization with people at the core. Characteristic towns as an essential link between new urbanization and rural ... ...

    Abstract The report to the 20th National Congress of the Communist Party of China highlighted the necessity of advancing a new type of urbanization with people at the core. Characteristic towns as an essential link between new urbanization and rural revitalization attach great importance to creating a beautiful environment. Sewage treatment is an indispensable foundation for a town's high-quality economic and social development; however, it may be hard to achieve through urban construction. Therefore, using data from 584 organic towns in Chongqing, a typical mountainous city in western China, this study empirically analyzes the effect of the characteristic town policy in China on mountainous sewage treatment and its mechanisms from 2014 to 2020. The results indicate that (1) the characteristic town policy helps enhance sewage treatment in small towns, which remains valid after a series of robustness tests. (2) Investment and human resource effects are mediators for the characteristic town policy to boost sewage treatment in small towns. Further analyses reveal that the boosting effect of the characteristic town policy on small-town sewage treatment is more significant for small towns with higher economic development levels suffering ecological and environmental pressures. These findings provide a basis for a broad recognition of the effect of the characteristic town policy and its impact. They also theoretically enrich the awareness of the Chinese government's urbanization policy concerning the economy and society.
    Language English
    Publishing date 2023-11-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e22830
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Diagnostic value of ultrasound elastography and conventional ultrasound for thyroid nodules: a meta-analysis.

    Chang, Donghua / Wang, Qin

    Quantitative imaging in medicine and surgery

    2023  Volume 13, Issue 3, Page(s) 1300–1311

    Abstract: Background: Thyroid nodular disease is a common disorder. Ultrasonography has emerged as a powerful tool for the diagnosis of thyroid disease owing to its high operational simplicity, non-invasiveness and reproducibility. This study aimed to ... ...

    Abstract Background: Thyroid nodular disease is a common disorder. Ultrasonography has emerged as a powerful tool for the diagnosis of thyroid disease owing to its high operational simplicity, non-invasiveness and reproducibility. This study aimed to systematically evaluate the value of ultrasound elastography and conventional ultrasound for the diagnosis of thyroid nodules.
    Methods: The PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure, Wanfang and VIP databases were searched systematically. RevMan 5.3 software was used to draw a risk bias map, and Stata 16.0 was used to plot a sensitivity and specificity forest map. A summary receiver operating characteristics (SROC) curve was plotted, and the area under the curve (AUC) was calculated. Meta-regression was used to explore the sources of heterogeneity.
    Results: The sensitivity of conventional ultrasonography for detecting thyroid nodules was 0.55 [95% confidence interval (CI): 0.45-0.65], the specificity was 0.90 (95% CI: 0.87-0.93), the positive likelihood ratio was 5.8 (95% CI: 3.8-8.9), the negative likelihood ratio was 0.49 (95% CI: 0.39-0.6), and the AUC was 0.86 (95% CI: 0.82-0.88). The sensitivity of ultrasonic elastography for detecting thyroid nodules was 0.67 (95% CI: 0.60-0.73), the specificity was 0.93 (95% CI: 0.90-0.95), the positive likelihood ratio was 9.1 (95% CI: 6.3-13.3), the negative likelihood ratio was 0.36 (95% CI: 0.29-0.44), and the AUC was 0.89 (95% CI: 0.86-0.91). The sensitivity of conventional ultrasound combined with ultrasonic elastography for detecting thyroid nodules was 0.88 (95% CI: 0.84-0.90), the specificity of the combined approach was 0.96 (95% CI: 0.93-0.98), the positive likelihood ratio was 23.3 (95% CI: 12.4-43.6), the negative likelihood ratio was 0.13 (95% CI: 0.10-0.17), and the AUC was 0.92 (95% CI: 0.90-0.94). Age, region, research type, conventional ultrasound evaluation criteria and elastography evaluation criteria had specific effects on sensitivity and specificity when detecting thyroid nodules.
    Conclusions: Conventional ultrasound can be used as a routine examination technique for the differential diagnosis of benign and malignant thyroid nodules, while ultrasound elastography can improve the sensitivity and specificity of the diagnosis. The diagnostic value of conventional ultrasound combined with ultrasound elastography is higher than that of a single diagnostic method.
    Language English
    Publishing date 2023-02-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 2653586-5
    ISSN 2223-4306 ; 2223-4292
    ISSN (online) 2223-4306
    ISSN 2223-4292
    DOI 10.21037/qims-22-505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Complete genomic sequencing of a

    Wang, Qin / Salman, Sayyed

    Microbiology resource announcements

    2023  Volume 13, Issue 1, Page(s) e0088523

    Abstract: This study presents a comprehensive analysis of the genomic sequence ... ...

    Abstract This study presents a comprehensive analysis of the genomic sequence of
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.00885-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Three genes expressed in relation to lipid metabolism considered as potential biomarkers for the diagnosis and treatment of diabetic peripheral neuropathy.

    Yang, Ye / Wang, Qin

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 8679

    Abstract: Diabetic neuropathy is one of the most common chronic complications and is present in approximately 50% of diabetic patients. A bioinformatic approach was used to analyze candidate genes involved in diabetic distal symmetric polyneuropathy and their ... ...

    Abstract Diabetic neuropathy is one of the most common chronic complications and is present in approximately 50% of diabetic patients. A bioinformatic approach was used to analyze candidate genes involved in diabetic distal symmetric polyneuropathy and their potential mechanisms. GSE95849 was downloaded from the Gene Expression Omnibus database for differential analysis, together with the identified diabetic peripheral neuropathy-associated genes and the three major metabolism-associated genes in the CTD database to obtain overlapping Differentially Expressed Genes (DEGs). Gene Set Enrichment Analysis and Functional Enrichment Analysis were performed. Protein-Protein Interaction and hub gene networks were constructed using the STRING database and Cytoscape software. The expression levels of target genes were evaluated using GSE24290 samples, followed by Receiver operating characteristic, curve analysis. And Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis were performed on the target genes. Finally, mRNA-miRNA networks were constructed. A total of 442 co-expressed DEGs were obtained through differential analysis, of which 353 expressed up-regulated genes and 89 expressed down-regulated genes. The up-regulated DEGs were involved in 742 GOs and 10 KEGG enrichment results, mainly associated with lipid metabolism-related pathways, TGF-β receptor signaling pathway, lipid transport, and PPAR signaling pathway. A total of 4 target genes (CREBBP, EP300, ME1, CD36) were identified. Analysis of subject operating characteristic curves indicated that CREBBP (AUC = 1), EP300 (AUC = 0.917), ME1 (AUC = 0.944) and CD36 (AUC = 1) may be candidate serum biomarkers for DPN. Conclusion: Diabetic peripheral neuropathy pathogenesis and progression is caused by multiple pathways, which also provides clinicians with potential therapeutic tools.
    MeSH term(s) Humans ; Diabetic Neuropathies/diagnosis ; Diabetic Neuropathies/genetics ; Gene Expression Profiling/methods ; Lipid Metabolism/genetics ; Gene Expression Regulation, Neoplastic ; Biomarkers ; Computational Biology/methods ; Diabetes Mellitus
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-05-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-35908-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Observation of the Effects of Extended Comfort Nursing on Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy.

    Wang, Qin / Hu, Beibei

    Alternative therapies in health and medicine

    2023  Volume 29, Issue 8, Page(s) 376–383

    Abstract: Objective: This study aimed to evaluate the clinical effects of providing extended comfort care to lung cancer patients undergoing chemotherapy and its impact on cancer-related fatigue levels.: Methods: Using a retrospective data analysis approach, a ...

    Abstract Objective: This study aimed to evaluate the clinical effects of providing extended comfort care to lung cancer patients undergoing chemotherapy and its impact on cancer-related fatigue levels.
    Methods: Using a retrospective data analysis approach, a total of 88 lung cancer patients receiving chemotherapy at our hospital from March 2021 to March 2022 were selected as research participants. They were divided into an observation group and a control group based on different nursing methods, with 44 patients in each group. The observation group received extended comfort nursing interventions, while the control group received routine nursing care. Patients' comfort levels in both groups were compared, and changes in cancer-related fatigue, self-efficacy, psychological state, coping style, sleep quality, and overall life quality were assessed.
    Results: Following the nursing interventions, patients in the observation group exhibited better physical, psychological, spiritual, sociocultural, and environmental well-being compared to the control group (P < .05). The observation group also showed lower scores for emotional exhaustion, physical exhaustion, cognitive exhaustion, and overall exhaustion compared to the control group (P < .05). Moreover, patients in the observation group demonstrated higher levels of self-efficacy on the health promotion strategy questionnaire (Supph) (P < .05) and lower scores on the self-rating anxiety and depressive symptoms scales (P < .05) after receiving nursing care. In terms of coping style, patients in the observation group exhibited lower avoidance and yield scores but higher face scores than the control group (P < .05). The observation group also reported higher overall life quality scale item grades (P < .05) and lower Pittsburgh Sleep Quality Index (PSQI) scores (P < .05) compared to the control group.
    Conclusions: Extended comfort care for lung cancer patients during chemotherapy improves emotional and physical comfort and effectively reduces cancer-related fatigue levels. These findings have significant implications for clinical practice.
    MeSH term(s) Humans ; Lung Neoplasms/complications ; Lung Neoplasms/drug therapy ; Retrospective Studies ; Fatigue/drug therapy ; Fatigue/etiology ; Anxiety/drug therapy ; Anxiety Disorders
    Language English
    Publishing date 2023-09-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Letter to the Editor From Zhang et al: Preoperative Serum Calcium Level Predicts Postoperative Mortality in Older Adult Patients With Hip Fracture: A Prospective Cohort Study of 2333 Patients.

    Zhang, Ying / Wang, Qin

    Journal of the American Medical Directors Association

    2023  , Page(s) 104879

    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Letter
    ZDB-ID 2171030-2
    ISSN 1538-9375 ; 1525-8610
    ISSN (online) 1538-9375
    ISSN 1525-8610
    DOI 10.1016/j.jamda.2023.10.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Significance of carcinoembryonic antigen detection in the early diagnosis of colorectal cancer: A systematic review and meta-analysis.

    Wang, Rui / Wang, Qin / Li, Pan

    World journal of gastrointestinal surgery

    2024  Volume 15, Issue 12, Page(s) 2907–2918

    Abstract: Background: Colorectal cancer (CRC) is a prevalent malignant tumor involving adenomas that develop into malignant lesions. Carcinoembryonic antigen (CEA) is a non-specific serum biomarker upregulated in CRC. The concentration of CEA is modulated by ... ...

    Abstract Background: Colorectal cancer (CRC) is a prevalent malignant tumor involving adenomas that develop into malignant lesions. Carcinoembryonic antigen (CEA) is a non-specific serum biomarker upregulated in CRC. The concentration of CEA is modulated by tumor stage and grade, tumor site in the colon, ploidy status, and patient smoking status. This study aimed to evaluate current evidence regarding the diagnostic power of CEA levels in the early detection of CRC recurrence in adults.
    Aim: To evaluate current evidence regarding the diagnostic power of CEA levels in the early detection of CRC recurrence in adults.
    Methods: A systematic search was performed using four databases: MEDLINE, Cochrane Trials, EMBASE, and the Web of Science. The inclusion criteria were as follows: Adult patients aged ≥ 18 years who had completed CRC curative treatment and were followed up postoperatively; reporting the number of CRC recurrences as an outcome; and randomized, clinical, cohort, and case-control study designs. Studies that were not published in English and animal studies were excluded. The following data were extracted by three independent reviewers: Study design, index tests, follow-up, patient characteristics, and primary outcomes. All statistical analyses were performed using the RevMan 5.4.1.
    Results: A total of 3232 studies were identified, with 73 remaining following the elimination of duplicates. After screening on predetermined criteria, 12 studies were included in the final analysis. At a reference standard of 5 mg/L, CEA detected only approximately half of recurrent CRCs, with a pooled sensitivity of 59% (range, 33%-83%) and sensitivity of 89% (range, 58%-97%).
    Conclusion: CEA is a significant marker for CRC diagnosis. However, it has insufficient sensitivity and specificity to be used as a single biomarker of early CRC recurrence, with an essential proportion of false negatives.
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2573700-4
    ISSN 1948-9366
    ISSN 1948-9366
    DOI 10.4240/wjgs.v15.i12.2907
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Association of vitamins with bone mineral density and osteoporosis measured by dual-energy x-ray absorptiometry: a cross-sectional study.

    Wang, Qin / Yu, Hanhua / Kong, Yuefeng

    BMC musculoskeletal disorders

    2024  Volume 25, Issue 1, Page(s) 69

    Abstract: Background: We aimed to assess the associations of vitamins intake with osteoporosis based on a national sample from US adults.: Methods: A total of 1536 participants were included in this cross-sectional study to investigate the relationship between ...

    Abstract Background: We aimed to assess the associations of vitamins intake with osteoporosis based on a national sample from US adults.
    Methods: A total of 1536 participants were included in this cross-sectional study to investigate the relationship between vitamins intake and osteoporosis from National Health and Nutrition Examination Survey, including vitamin A, C, D. Logistic regression models were used to assess the associations between dietary vitamin intake and osteoporosis.
    Results: We found that vitamins intake were negatively associated with osteoporosis. For vitamin A, compared with the first tertile, the odds ratios (ORs) and 95% confidential intervals (CIs) were 0.93 (0.81-1.04) for the second tertile and 0.85 (0.78-0.96) for the third tertile (P < 0.01). For vitamin C, compared with the first tertile, the ORs and 95% CIs were 0.89 (0.78-1.05) for the second tertile and 0.79 (0.67-0.93) for the third tertile (P < 0.01). For vitamin D, compared with the first tertile, the odds ratios (ORs) and 95% confidential intervals (CIs) were 0.94 (0.82-1.07) for the second tertile and 0.88 (0.75-0.98) for the third tertile (P < 0.01). And the negative association between vitamins intake and osteoporosis were more evident for female, aged ≥ 60, and BMI > 30, including vitamin A, C and D.
    Conclusions: Our findings provide evidence that vitamins intake is linked with decreased prevalence of osteoporosis, including vitamin A, C, D. Further large-scale prospective cohort studies are needed to verify our findings.
    MeSH term(s) Adult ; Female ; Humans ; Bone Density ; Vitamins ; Absorptiometry, Photon ; Cross-Sectional Studies ; Vitamin A ; Nutrition Surveys ; Prospective Studies ; Osteoporosis/diagnostic imaging ; Osteoporosis/epidemiology ; Vitamin K
    Chemical Substances Vitamins ; Vitamin A (11103-57-4) ; Vitamin K (12001-79-5)
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041355-5
    ISSN 1471-2474 ; 1471-2474
    ISSN (online) 1471-2474
    ISSN 1471-2474
    DOI 10.1186/s12891-024-07173-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Multi-timescale variation characteristics of PM

    Liu, Rui / Shao, Min / Wang, Qin'geng

    The Science of the total environment

    2024  Volume 920, Page(s) 171008

    Abstract: Over the past decade, China has achieved a significant reduction in ... ...

    Abstract Over the past decade, China has achieved a significant reduction in PM
    Language English
    Publishing date 2024-02-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.171008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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