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Article: [Analysis of verification results of protective effects of hearing protectors in different industries].

Shi, H X / Su, S B / Liu, M / Li, R Z / Wang, T J / Xiao, B

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

2023 Volume 41, Issue 5, Page(s) 333–337

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Male ; Humans ; Adult ; Hearing Loss, Noise-Induced/prevention & control ; Ear Protective Devices ; Noise, Occupational/prevention & control ; Hearing ; Audiometry
Language	Chinese
Publishing date	2023-05-09
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1050900-8
ISSN	1001-9391
ISSN	1001-9391
DOI	10.3760/cma.j.cn121094-20211026-00516
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Zs.A 7219: Show issues

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Article: [Risk prediction and function evaluation by T-cell epitope model and expression model of HLA-DPB1 mismatching in unrelated-donor hematopoietic stem cell transplantations].

Qi, J / Wang, T J / Wang, M N / Shang, L X / Chen, L / Wang, X F / Li, Y H / Xu, H / Ma, C F

Zhonghua yi xue za zhi

2024 Volume 104, Issue 11, Page(s) 850–856

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Male ; Female ; Humans ; Child ; Adolescent ; Young Adult ; Adult ; Epitopes, T-Lymphocyte/genetics ; Retrospective Studies ; Hematopoietic Stem Cell Transplantation ; HLA-DP beta-Chains/genetics ; Unrelated Donors ; Graft vs Host Disease/genetics
Chemical Substances	HLA-DPB1 antigen ; Epitopes, T-Lymphocyte ; HLA-DP beta-Chains
Language	Chinese
Publishing date	2024-02-26
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	132513-9
ISSN	0376-2491
ISSN	0376-2491
DOI	10.3760/cma.j.cn112137-20231203-01275
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Article ; Online: Associations of IL-1β and IL-6 gene polymorphisms with Parkinson's disease.

Li, N / Wang, J-X / Huo, T-T / Zhao, J-R / Wang, T-J

European review for medical and pharmacological sciences

2021 Volume 25, Issue 2, Page(s) 890–897

Abstract: Objective: The aim of this study was to explore the associations of interleukin-1β (IL-1β) and IL-6 gene polymorphisms with the pathogenesis of Parkinson's disease.: Patients and methods: A total of 200 patients with Parkinson's disease in our ... ...

Abstract	Objective: The aim of this study was to explore the associations of interleukin-1β (IL-1β) and IL-6 gene polymorphisms with the pathogenesis of Parkinson's disease. Patients and methods: A total of 200 patients with Parkinson's disease in our hospital were collected as the disease group. Meanwhile, 200 healthy subjects were taken as the control group. Peripheral blood samples were drawn from all research subjects. The polymorphic regions of IL-1β and IL-6 were amplified via polymerase chain reaction (PCR). Moreover, the polymorphisms were detected and analyzed, followed by further analysis based on the changes in gene expressions and Hoehn-Yahr grade of patients. Results: The allele distributions at IL-1β rs571556428 (p=0.015) and IL-6 rs543214973 (p=0.012) were statistically different between control group and disease group. In disease group, the G allele frequency at IL-1β rs571556428 and T allele frequency at IL-6 rs543214973 were significantly higher (p<0.05). Genotype distributions at IL-1β rs572292175 (p=0.017) and rs571556428 (p=0.000), and IL-6 rs543214973 (p=0.002) in disease group were also different from those in control group. In addition, the frequencies of CT genotype at IL-1β rs572292175, AA genotype at IL-1β rs571556428 and AA genotype at IL-6 rs543214973 in disease group were significantly lower (p<0.05). After modeling and analysis, it was found that the distribution of recessive model at IL-1β rs571556428 (p=0.012) and IL-6 rs543214973 (p=0.014) in disease group exhibited significant differences from those in control group. The frequencies of TA haplotype at IL-1β rs572292175 and rs571556428 (p=0.038) and GA haplotype at IL-6 rs1474348 and rs543214973 (p=0.047) in disease group were lower than those in control group (p<0.05). The polymorphisms at IL-1β rs571556428 and IL-6 rs1474348 were significantly associated with gene expression (p<0.05). Moreover, the expressions of IL-1β and IL-6 rose significantly in patients with GG genotype at rs571556428 and CG genotype at rs1474348, respectively (p<0.05). Furthermore, the polymorphism at IL-1β rs571556428 was significantly correlated with the grade of Parkinson's disease (p=0.000). Parkinson's disease was in a higher grade (grade 4-5) in patients with AA genotype, whereas in a lower grade (grade 1-2) in patients with GG and AG genotypes. Conclusions: IL-1β and IL-6 gene polymorphisms are significantly associated with the pathogenesis of Parkinson's disease.
MeSH term(s)	Female ; Humans ; Interleukin-1beta/blood ; Interleukin-1beta/genetics ; Interleukin-6/blood ; Interleukin-6/genetics ; Male ; Middle Aged ; Parkinson Disease/blood ; Parkinson Disease/diagnosis ; Parkinson Disease/genetics ; Polymorphism, Genetic/genetics
Chemical Substances	IL1B protein, human ; IL6 protein, human ; Interleukin-1beta ; Interleukin-6
Language	English
Publishing date	2021-02-12
Publishing country	Italy
Document type	Journal Article
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
DOI	10.26355/eurrev_202101_24657
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Zs.A 1887: Show issues

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Book ; Online: Role of Compressive Viscosity and Thermal Conductivity on the Damping of Slow Waves in the Coronal Loops With and Without Heating-Cooling Imbalance

Prasad, Abhinav / Srivastava, A. K. / Wang, T. J.

2020

Abstract: In the present paper, we derive a new dispersion relation for slow magnetoacoustic waves invoking the effect of thermal conductivity, compressive viscosity, radiation and unknown heating term along with the consideration of heating cooling imbalance from ...

Abstract	In the present paper, we derive a new dispersion relation for slow magnetoacoustic waves invoking the effect of thermal conductivity, compressive viscosity, radiation and unknown heating term along with the consideration of heating cooling imbalance from linearized MHD equations. We solve the general dispersion relation to understand role of compressive viscosity and thermal conductivity in damping of the slow waves in coronal loops with and without heating cooling imbalance. We have analyzed wave damping for the range of loop length $L$=50-500 Mm, temperature $T$=5-30 MK, and density $\rho$=10$^{-11}$-10$^{-9}$ kg m$^{-3}$. It was found that inclusion of compressive viscosity along with thermal conductivity significantly enhances the damping of fundamental mode oscillations in shorter (e.g., $L$=50 Mm) and super-hot ($T>$10 MK) loops. However, role of the viscosity in damping is insignificant in longer (e.g., $L$=500 Mm) and hot loops (T$\leq$10 MK) where, instead, thermal conductivity along with the presence of heating cooling imbalance plays a dominant role. For the shorter loops at the super-hot regime of the temperature, increment in loop density substantially enhances damping of the fundamental modes due to thermal conductivity when the viscosity is absent, however, when the compressive viscosity is added the increase in density substantially weakens damping. Thermal conductivity alone is found to play a dominant role in longer loops at lower temperatures (T$\leq$10 MK), while compressive viscosity dominates in damping at super-hot temperatures ($T>$10 MK) in shorter loops. The predicted scaling law between damping time ($\tau$) and wave period ($P$) is found to better match to observed SUMER oscillations when heating cooling imbalance is taken into account in addition to thermal conductivity and compressive viscosity for the damping of the fundamental slow mode oscillations. Comment: 40 Pages; 13 Figures; 01 Table; Solar Physics (in press)
Keywords	Astrophysics - Solar and Stellar Astrophysics
Subject code	621
Publishing date	2020-11-29
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: [A clinical analysis of adenovirus infection diagnosed by metagenomic next-generation sequencing or the diagnosis of adenovirus infection after haploidentical hematopoietic stem cell transplantation clinical analysis of six cases].

Wu, Y J / Chen, F / Zhao, Y / Zhang, Y M / Cao, J J / Lin, G Q / Wang, T J / Xia, J / Tang, X W / Xue, S L / Jin, Z M / Wu, D P

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

2023 Volume 43, Issue 10, Page(s) 869–872

MeSH term(s)	Humans ; Hematopoietic Stem Cell Transplantation ; Adenoviridae Infections/diagnosis ; High-Throughput Nucleotide Sequencing ; Graft vs Host Disease ; Transplantation Conditioning
Language	Chinese
Publishing date	2023-01-27
Publishing country	China
Document type	Journal Article
ZDB-ID	2997162-7
ISSN	0253-2727 ; 0253-2727
ISSN (online)	0253-2727
ISSN	0253-2727
DOI	10.3760/cma.j.issn.0253-2727.2022.10.013
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Article: Gender difference in radiotherapy-induced carotid stenosis.

Yang, Y / Yang, W / Wang, T J

Journal of biological regulators and homeostatic agents

2017 Volume 31, Issue 3, Page(s) 631–637

Abstract: Radiotherapy (RT) is often the first choice of treatment for cancer of the larynx. Studies have shown that the incidence of carotid stenosis (CS) after radiotherapy of laryngeal cancer is increasing, and that gender difference in radiotherapy-induced ... ...

Abstract	Radiotherapy (RT) is often the first choice of treatment for cancer of the larynx. Studies have shown that the incidence of carotid stenosis (CS) after radiotherapy of laryngeal cancer is increasing, and that gender difference in radiotherapy-induced side effects exist. Thus, we examined the gender difference in the incidence of CS and the impact of microinflammatory factors after radiotherapy. We reported this study on patients who received radiotherapy as part of the treatment for laryngeal cancer in the Jilin Province in China. One hundred sixty-four males and 152 females were treated with radiotherapy between 2006 and 2016. The carotid diameter was determined by measuring carotid intima-media thickness in the common, external and internal carotid artery. Microinflammatory conditions were assessed by measuring the level of high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α). Other studied risk factors included age, treatment modalities, radiation dose and energy, the height of the radiation field, and the follow-up time. CS was detected in 161 (50.9%) of the 316 patients. Carotid stenosis was mainly clinically unsuspected, two patients had anamnesis of unconsciousness. Importantly, fewer women (36.1%) had CS than men (64.6%) (p=0.004). Furthermore, male patients showed higher serum levels of hs-CRP, IL-6, and TNF-α. Taken together, our study suggested that women underoing radiotherapy of laryngeal cancer are less likely to have CS than men. Therefore, routine assessment after irradiation of laryngeal cancer seems necessary for clinical detection of asymptomatic CS, particularly in male patients.
Language	English
Publishing date	2017-07
Publishing country	Italy
Document type	Journal Article
ZDB-ID	639196-5
ISSN	1724-6083 ; 0393-974X
ISSN (online)	1724-6083
ISSN	0393-974X
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Zs.A 2270: Show issues

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Article: [Intravenous sedation with midazolam and propofol target controlled infusion on patients'perioperative anxiety under the mandibular third molar extraction].

Wang, T J / Liu, Y / Guan, M

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

2017 Volume 49, Issue 6, Page(s) 1044–1049

Abstract: Objective: To evaluate whether midazolam with propofol target controlled infusion (TCI) intravenous sedation during the mandibular third molar extraction influences patients'perioperative anxiety.: Methods: The subjects were patients who planned to ... ...

Abstract	Objective: To evaluate whether midazolam with propofol target controlled infusion (TCI) intravenous sedation during the mandibular third molar extraction influences patients'perioperative anxiety. Methods: The subjects were patients who planned to undergo the mandibular third molar extraction in Peking University School and Hospital of Stomatology, whose state anxiety inventory (SAI) scores were≥38 at the initial visit. They were divided into intravenous sedation group (IVS) and local anesthesia group (LA) on the basis of the planned intravenous sedation. Each group was divided into two subgroups according to the overall SAI scores at the initial visit: IVS-I, LA-I (SAI: 38-50) and IVS-II, LA-II (SAI: 51-80). The anxiety before and after the surgery was evaluated by the SAI scores at the initial visit (T1), before surgery (T2) and 7 days after surgery (T3). The anxiety during the surgery was evaluated by the heart rate, blood pressure and visual analogue scale (VAS) scores. Results: There were no significant differences on SAI at T1, T2, and T3 in the two groups (P>0.05). The heart rate, blood pressure and VAS pain scores of IVS group were significantly lower than those of LA group during the surgery (P<0.001). Conclusion: Intravenous sedation with midazolam and propofol TCI was effective on the patients' anxiety during the third molar extraction, which successfully made the patients more comfortable and their heart rate, blood pressure and oxygen saturation more stable during the surgery. But there were no significant differences on the patients'anxiety at the initial visit (T1), before surgery (T2) and 7 days after surgery (T3) according to the SAI scores in the two groups.
MeSH term(s)	Anesthesia, Local ; Anesthetics, Intravenous/therapeutic use ; Anxiety/drug therapy ; Blood Pressure ; Conscious Sedation ; Heart Rate ; Humans ; Infusions, Intravenous ; Mandible ; Midazolam/therapeutic use ; Molar, Third ; Propofol/therapeutic use ; Tooth Extraction
Chemical Substances	Anesthetics, Intravenous ; Midazolam (R60L0SM5BC) ; Propofol (YI7VU623SF)
Language	Chinese
Publishing date	2017-12-18
Publishing country	China
Document type	Journal Article
ISSN	1671-167X
ISSN	1671-167X
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Article ; Online: Identifying novel biomarkers for cardiovascular disease risk prediction.

Ge, Y / Wang, T J

Journal of internal medicine

2012 Volume 272, Issue 5, Page(s) 430–439

Abstract: The primary prevention of cardiovascular disease relies on the ability to identify at-risk individuals long before the development of overt events. In the past decade, research into circulating, genetic and imaging biomarkers to augment traditional ... ...

Abstract	The primary prevention of cardiovascular disease relies on the ability to identify at-risk individuals long before the development of overt events. In the past decade, research into circulating, genetic and imaging biomarkers to augment traditional methods of risk prediction has only achieved modest success. Emerging technologies in the fields of genomics, metabolomics and proteomics are providing new platforms for biomarker discovery. Here, we review current concepts in the evaluation and discovery of cardiovascular biomarkers. Further research is needed to identify new biomarkers to successfully stratify risk of cardiovascular disease in low-risk populations, as well as to test whether management strategies informed by biomarker testing are better than standard of care.
MeSH term(s)	Biomarkers/metabolism ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/prevention & control ; Genomics ; Humans ; Metabolomics ; Primary Prevention/methods ; Primary Prevention/standards ; Proteomics ; Risk Factors
Chemical Substances	Biomarkers
Language	English
Publishing date	2012-11
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	96274-0
ISSN	1365-2796 ; 0954-6820
ISSN (online)	1365-2796
ISSN	0954-6820
DOI	10.1111/j.1365-2796.2012.02589.x
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Article: [The short-term and long-term prognostic analysis in patients with chronic total occlusion acute non-ST segment elevation myocardial infarction].

Wang, T J / Dong, J L / Yan, S / Chen, G H / Chen, G / Zhao, Y Y / Qian, H Y / Yuan, J S / Song, L / Qiao, S B / Yang, J G / Yang, W X / Yang, Yuejin

Zhonghua nei ke za zhi

2022 Volume 61, Issue 4, Page(s) 384–389

Abstract: Objectives: ...

Abstract	Objectives:
MeSH term(s)	Coronary Occlusion/complications ; Follow-Up Studies ; Humans ; Non-ST Elevated Myocardial Infarction/complications ; Percutaneous Coronary Intervention/adverse effects ; Prognosis
Language	Chinese
Publishing date	2022-03-27
Publishing country	China
Document type	Journal Article
ZDB-ID	754223-9
ISSN	0578-1426
ISSN	0578-1426
DOI	10.3760/cma.j.cn112138-20210626-00445
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Zs.A 1620: Show issues

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Article: [The acute and long-term outcome of patients with ST segment elevation myocardial infarction concurrent with chronic total occlusion].

Wang, T J / Dong, J L / Wang, Y / Zhao, Y Y / Chen, G / Qian, H Y / Yuan, J S / Song, L / Qiao, S B / Yang, J G / Yang, W X / Yang, Y J

Zhonghua xin xue guan bing za zhi

2021 Volume 49, Issue 6, Page(s) 586–592

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Aged ; China ; Chronic Disease ; Coronary Occlusion/complications ; Humans ; Male ; Middle Aged ; Myocardial Infarction ; Percutaneous Coronary Intervention ; Risk Factors ; ST Elevation Myocardial Infarction/complications ; ST Elevation Myocardial Infarction/surgery ; Treatment Outcome
Language	Chinese
Publishing date	2021-04-07
Publishing country	China
Document type	Journal Article
ZDB-ID	603425-1
ISSN	0253-3758
ISSN	0253-3758
DOI	10.3760/cma.j.cn112148-20201012-00805
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