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  1. Article ; Online: Intelligent Scanning Detection System of Muscle Exercise Fatigue Based on Surface Electromyography.

    Wang, Weiqi

    publication RETRACTED

    Scanning

    2022  Volume 2022, Page(s) 9163978

    Abstract: In order to use the surface EMG signal ... ...

    Abstract In order to use the surface EMG signal to
    MeSH term(s) Electromyography/methods ; Humans ; Muscle Fatigue/physiology ; Muscles
    Language English
    Publishing date 2022-08-27
    Publishing country England
    Document type Journal Article ; Retracted Publication
    ZDB-ID 391900-6
    ISSN 1932-8745 ; 0161-0457
    ISSN (online) 1932-8745
    ISSN 0161-0457
    DOI 10.1155/2022/9163978
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3871: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: The host mannose-6-phosphate pathway and viral infection.

    Liu, Qincheng / Wang, Weiqi / Xu, Liwei / Zhang, Qisheng / Wang, Hongna

    Frontiers in cellular and infection microbiology

    2024  Volume 14, Page(s) 1349221

    Abstract: Viruses, despite their simple structural composition, engage in intricate and complex interactions with their hosts due to their parasitic nature. A notable demonstration of viral behavior lies in their exploitation of lysosomes, specialized organelles ... ...

    Abstract Viruses, despite their simple structural composition, engage in intricate and complex interactions with their hosts due to their parasitic nature. A notable demonstration of viral behavior lies in their exploitation of lysosomes, specialized organelles responsible for the breakdown of biomolecules and clearance of foreign substances, to bolster their own replication. The man-nose-6-phosphate (M6P) pathway, crucial for facilitating the proper transport of hydrolases into lysosomes and promoting lysosome maturation, is frequently exploited for viral manipulation in support of replication. Recently, the discovery of lysosomal enzyme trafficking factor (LYSET) as a pivotal regulator within the lysosomal M6P pathway has introduced a fresh perspective on the intricate interplay between viral entry and host factors. This groundbreaking revelation illuminates unexplored dimensions of these interactions. In this review, we endeavor to provide a thorough overview of the M6P pathway and its intricate interplay with viral factors during infection. By consolidating the current understanding in this field, our objective is to establish a valuable reference for the development of antiviral drugs that selectively target the M6P pathway.
    MeSH term(s) Humans ; Hydrolases/metabolism ; Mannosephosphates/analysis ; Mannosephosphates/chemistry ; Mannosephosphates/metabolism ; Virus Diseases/metabolism ; Lysosomes/metabolism
    Chemical Substances mannose-6-phosphate (3672-15-9) ; Hydrolases (EC 3.-) ; Mannosephosphates
    Language English
    Publishing date 2024-01-31
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2024.1349221
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  3. Article ; Online: Investigation of high-dose radiotherapy's effect on brain structure aggravated cognitive impairment and deteriorated patient psychological status in brain tumor treatment.

    Ma, Jianpeng / Cao, Hetao / Hou, Dongmei / Wang, Weiqi / Liu, Tingting

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 10149

    Abstract: This study aims to investigate the potential impact of high-dose radiotherapy (RT) on brain structure, cognitive impairment, and the psychological status of patients undergoing brain tumor treatment. We recruited and grouped 144 RT-treated patients with ... ...

    Abstract This study aims to investigate the potential impact of high-dose radiotherapy (RT) on brain structure, cognitive impairment, and the psychological status of patients undergoing brain tumor treatment. We recruited and grouped 144 RT-treated patients with brain tumors into the Low dose group (N = 72) and the High dose group (N = 72) according to the RT dose applied. Patient data were collected by using the HADS and QLQ-BN20 system for subsequent analysis and comparison. Our analysis showed no significant correlation between the RT doses and the clinicopathological characteristics. We found that a high dose of RT could aggravate cognitive impairment and deteriorate patient role functioning, indicated by a higher MMSE and worsened role functioning in the High dose group. However, the depression status, social functioning, and global health status were comparable between the High dose group and the Low dose group at Month 0 and Month 1, while being worsened in the High dose group at Month 3, indicating the potential long-term deterioration of depression status in brain tumor patients induced by high-dose RT. By comparing patient data at Month 0, Month 1, Month 3, Month 6, and Month 9 after RT, we found that during RT treatment, RT at a high dose could aggravate cognitive impairment in the short term and lead to worsened patient role functioning, and even deteriorate the overall psychological health status of patients in the long term.
    MeSH term(s) Humans ; Male ; Female ; Cognitive Dysfunction/etiology ; Brain Neoplasms/radiotherapy ; Brain Neoplasms/psychology ; Middle Aged ; Aged ; Brain/radiation effects ; Brain/pathology ; Adult ; Radiotherapy Dosage ; Depression/etiology ; Quality of Life
    Language English
    Publishing date 2024-05-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-59694-0
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  4. Article ; Online: AlF-AlF Reaction Dynamics between 200 K and 1000 K: Reaction Mechanisms and Intermediate Complex Characterization.

    Wang, Weiqi / Liu, Xiangyue / Pérez-Ríos, Jesús

    Molecules (Basel, Switzerland)

    2023  Volume 29, Issue 1

    Abstract: AlF is a relevant molecule in astrochemistry as a tracer of F-bearing molecules. Additionally, AlF presents diagonal Franck-Condon factors and can be created very efficiently in the lab, which makes it a prototypical molecular for laser cooling. However, ...

    Abstract AlF is a relevant molecule in astrochemistry as a tracer of F-bearing molecules. Additionally, AlF presents diagonal Franck-Condon factors and can be created very efficiently in the lab, which makes it a prototypical molecular for laser cooling. However, very little is known about the reaction dynamics of AlF. In this work, we report on the reaction dynamics of AlF-AlF between 200 and 1000 K using
    Language English
    Publishing date 2023-12-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29010222
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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  5. Article ; Online: Efficacy Analysis of Neoadjuvant versus Adjuvant Cisplatin-Paclitaxel Regimens for Initial Treatment of FIGO Stages IB3 and IIA2 Cervical Cancer.

    Tao, Wei / Wang, Weiqi / Zhai, Jingfang / Guo, Linlin

    Medical science monitor : international medical journal of experimental and clinical research

    2023  Volume 29, Page(s) e940545

    Abstract: BACKGROUND Large cancer lesions are often challenging to treat with surgical intervention alone. Neoadjuvant chemotherapy is frequently used for FIGO stage IB3 and IIA2 cervical cancers to optimize the outcomes of radical surgeries. This study aimed to ... ...

    Abstract BACKGROUND Large cancer lesions are often challenging to treat with surgical intervention alone. Neoadjuvant chemotherapy is frequently used for FIGO stage IB3 and IIA2 cervical cancers to optimize the outcomes of radical surgeries. This study aimed to compare the effectiveness of neoadjuvant chemotherapy, followed by adjuvant chemotherapy and radiotherapy, if necessary, with the traditional approach of adjuvant chemotherapy and radiotherapy after radical hysterectomy in treatment-naïve patients with cervical cancer of specified stages. MATERIAL AND METHODS A total of 245 female patients were administered either 70 to 85 mg/m² cisplatin and 165 to 175 mg/m² paclitaxel every 21 days (2 cycles) prior to radical hysterectomy, followed by adjuvant chemotherapy and radiotherapy if needed (neoadjuvant therapy, NT cohort, n=105), or received adjuvant chemotherapy and radiotherapy after radical hysterectomy adjuvant therapy, AT cohort, n=140). RESULTS In the NT cohort, 76% of patients responded to neoadjuvant chemotherapy, while 24% did not. Adverse operative, intraoperative, and postoperative outcomes were significantly more common among the non-responders (P<0.05). After 5 years, 91% of responders and 72% of non-responders survived without recurrence (P=0.0372), and 3% of responders and 28% of non-responders had died (P=0.0005). CONCLUSIONS The resistance to neoadjuvant chemotherapy is a poor prognostic factor. Neoadjuvant chemotherapy followed by radical hysterectomy and adjuvant chemotherapy/radiotherapy appears to be advantageous for cervical cancer patients who respond well to neoadjuvant chemotherapy.
    MeSH term(s) Humans ; Female ; Neoadjuvant Therapy/methods ; Cisplatin/therapeutic use ; Uterine Cervical Neoplasms/drug therapy ; Uterine Cervical Neoplasms/pathology ; Neoplasm Staging ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Paclitaxel/therapeutic use ; Chemotherapy, Adjuvant ; Hysterectomy/methods
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2023-12-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1439041-3
    ISSN 1643-3750 ; 1234-1010
    ISSN (online) 1643-3750
    ISSN 1234-1010
    DOI 10.12659/MSM.940545
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4924: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: Molecular dynamics-driven global potential energy surfaces: Application to the AlF dimer.

    Liu, Xiangyue / Wang, Weiqi / Pérez-Ríos, Jesús

    The Journal of chemical physics

    2023  Volume 159, Issue 14

    Abstract: In this work, we present a full-dimensional potential energy surface for AlF-AlF. We apply a general machine learning approach for full-dimensional potential energy surfaces, employing an active learning scheme trained on ab initio points, whose size ... ...

    Abstract In this work, we present a full-dimensional potential energy surface for AlF-AlF. We apply a general machine learning approach for full-dimensional potential energy surfaces, employing an active learning scheme trained on ab initio points, whose size grows based on the accuracy required. The training points are selected based on molecular dynamics simulations, choosing the most suitable configurations for different collision energy and mapping the most relevant part of the potential energy landscape of the system. The present approach does not require long-range information and is entirely general. As a result, it is possible to provide the full-dimensional AlF-AlF potential energy surface, requiring ≲0.01% of the configurations to be calculated ab initio. Furthermore, we analyze the general properties of the AlF-AlF system, finding critical differences with other reported results on CaF or bi-alkali dimers.
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0169080
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    In stock of ZB MED Bonn / Germany

    Z 4' 49/16: Show issues

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  7. Article ; Online: Minor allele of rs11655237 in linc-00673 improves bone mineral density and decreases the risk of osteoporosis.

    Ma, Jianpeng / Hou, Dongmei / Wang, Weiqi / Liu, Tingting

    Asian journal of surgery

    2023  Volume 46, Issue 11, Page(s) 5122–5123

    MeSH term(s) Humans ; Bone Density ; Alleles ; Osteoporosis ; Genetic Predisposition to Disease
    Language English
    Publishing date 2023-07-19
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.06.116
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2831: Show issues Location:
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  8. Article: Effect of Macro Fibers on the Permeability and Crack Surface Topography of Layered Fiber Reinforced Concrete.

    Zeng, Wei / Wang, Weiqi / Wang, Qiannan / Li, Mengya / Zhang, Lining / Tong, Yunyun

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 8

    Abstract: This paper describes the effects of macro fibers on permeability and crack surface topography of layered fiber-reinforced concrete (FRC) specimens with different layering ratios under uniaxial tensile load. The crack permeability of layered FRC specimens ...

    Abstract This paper describes the effects of macro fibers on permeability and crack surface topography of layered fiber-reinforced concrete (FRC) specimens with different layering ratios under uniaxial tensile load. The crack permeability of layered FRC specimens is investigated by a self-designed permeability setup. The topographical analysis of crack surfaces is investigated by a custom-designed laser scanning setup. The results show that when the fiber volume content and layering ratio of the FRC layer are constant, the tensile toughness of layered FRC specimens depends on the proportion of steel fiber in macro fibers, and with an increase in the proportion of steel fiber, the tensile toughness of layered FRC specimens increases. For the layered FRC specimens, the crack permeability is much lower than that of the normal concrete (NC) specimen. A significant positive synergistic effect on crack impermeability can be achieved by the combination of steel fiber and polypropylene fiber in the SF80PP2.3 specimen. The crack surface roughness parameter (
    Language English
    Publishing date 2024-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17081733
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  9. Article: Hybrid Fiber Influence on the Crack Permeability of Cracked Concrete Exposed to Freeze-Thaw Cycles.

    Zeng, Wei / Wang, Weiqi / Wang, Qiannan / Li, Mengya / Zhang, Lining / Tong, Yunyun

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 8

    Abstract: This paper describes hybrid fiber's influence on the crack permeability of cracked concrete exposed to freeze-thaw cycles. A permeability setup and a laser-scanning setup have been designed to measure the crack permeability and the fractured surface ... ...

    Abstract This paper describes hybrid fiber's influence on the crack permeability of cracked concrete exposed to freeze-thaw cycles. A permeability setup and a laser-scanning setup have been designed to measure the crack permeability and the fractured surface roughness of cracked hybrid fiber-reinforced concrete, containing polypropylene fiber and steel fiber, under a splitting tensile load. The results show that, when the effective crack width of the specimens is less than 25 μm, the rough crack surface significantly reduces the concrete's crack permeability. As the crack width increases, the effect of the concrete crack surface on crack permeability gradually decreases, and the crack permeability of the concrete is closer to the Poiseuille flow model. The permeability parameter
    Language English
    Publishing date 2024-04-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17081819
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  10. Article ; Online: Stibnite dissolution and Sb oxidation by Paraccocus versutus XT0.6 via direct and indirect contact.

    Li, Min / Wang, Weiqi / Wu, Mengxiaojun / Lei, Jingwen / Lu, Xiaolu / Wang, Hongmei

    Journal of hazardous materials

    2024  Volume 467, Page(s) 133731

    Abstract: In this study Paraccocus versutus XT0.6 was employed to address the mechanism of microbial dissolution and oxidation of stibnite. Results showed that with the growth of XT0.6, pH increased to 9.0 in both microbe-mineral contact (MM) and microbe-mineral ... ...

    Abstract In this study Paraccocus versutus XT0.6 was employed to address the mechanism of microbial dissolution and oxidation of stibnite. Results showed that with the growth of XT0.6, pH increased to 9.0 in both microbe-mineral contact (MM) and microbe-mineral non-contact groups (M[M]). Dissolved Sb(III) was released from stibnite, which was subsequently quickly oxidized to Sb(V) completely in MM and partially in M[M] groups. On the contrast, the final pH decreased to 6.5 and 4.9, respectviely, in system amended with extracellular secretion (EM) of XT0.6 and abiotic groups. Dissolution of stibnite and oxidation of Sb(III) were also observed in EM group, suggesting a potential contribution of extracellular enzyme in Sb(III) oxidation. The dissolution and oxidation rates were the highest in MM group, followed by those in M[M], EM and abiotic groups. To be noted, Sb(V) concentration decreased in MM group on the fifth day, which might indicate the formation of Sb(V)-bearing secondary mineral. Genome of XT0.6 consisted of two chromosomes and one plasmid, and most genes responsible for antimony oxidation and antimony resistance were located on the chromosomes. Proteomics analysis of the extracellular secretions indicated the up-regulated proteins were mainly related to electron-transfer, suggesting their potential role in Sb(III) oxidation.
    MeSH term(s) Antimony ; Oxidation-Reduction ; Electron Transport ; Proteomics ; Minerals
    Chemical Substances Antimony (9IT35J3UV3) ; Minerals
    Language English
    Publishing date 2024-02-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2024.133731
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