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  1. Article: Laser Welding of Fiber and Quartz Glass Ferrule.

    Wang, Wenhua

    Micromachines

    2023  Volume 14, Issue 5

    Abstract: Optical fiber sensors fabricated by bonding have several limitations. To address these limitations, a ... ...

    Abstract Optical fiber sensors fabricated by bonding have several limitations. To address these limitations, a CO
    Language English
    Publishing date 2023-04-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi14050939
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Fabry-Perot Interference Fiber Acoustic Wave Sensor Based on Laser Welding All-Silica Glass.

    Wang, Wenhua

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 7

    Abstract: Due to the small difference between the thermal expansion coefficients of silica optical fiber and silica glass, they are used as probe materials of optical fiber acoustic wave sensors. According to the light absorption characteristics of a pressure- ... ...

    Abstract Due to the small difference between the thermal expansion coefficients of silica optical fiber and silica glass, they are used as probe materials of optical fiber acoustic wave sensors. According to the light absorption characteristics of a pressure-sensitive silica diaphragm and silica glass, the laser welding of an all-silica Fabry-Perot (FP) interference optical fiber acoustic wave sensor with a CO
    Language English
    Publishing date 2022-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15072484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Gasdermins in sepsis.

    Wang, Wenhua / He, Zhihui

    Frontiers in immunology

    2023  Volume 14, Page(s) 1203687

    Abstract: Sepsis is a hyper-heterogeneous syndrome in which the systemic inflammatory response persists throughout the course of the disease and the inflammatory and immune responses are dynamically altered at different pathogenic stages. Gasdermins (GSDMs) ... ...

    Abstract Sepsis is a hyper-heterogeneous syndrome in which the systemic inflammatory response persists throughout the course of the disease and the inflammatory and immune responses are dynamically altered at different pathogenic stages. Gasdermins (GSDMs) proteins are pore-forming executors in the membrane, subsequently mediating the release of pro-inflammatory mediators and inflammatory cell death. With the increasing research on GSDMs proteins and sepsis, it is believed that GSDMs protein are one of the most promising therapeutic targets in sepsis in the future. A more comprehensive and in-depth understanding of the functions of GSDMs proteins in sepsis is important to alleviate the multi-organ dysfunction and reduce sepsis-induced mortality. In this review, we focus on the function of GSDMs proteins, the molecular mechanism of GSDMs involved in sepsis, and the regulatory mechanism of GSDMs-mediated signaling pathways, aiming to provide novel ideas and therapeutic strategies for the diagnosis and treatment of sepsis.
    MeSH term(s) Humans ; Gasdermins ; Sepsis ; Cell Death ; Inflammation Mediators ; Syndrome
    Chemical Substances Gasdermins ; Inflammation Mediators
    Language English
    Publishing date 2023-11-03
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1203687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: TIGIT: A potential immunotherapy target for gynecological cancers.

    Jiang, Siyue / Wang, Wenhua / Yang, Yongxiu

    Pathology, research and practice

    2024  Volume 255, Page(s) 155202

    Abstract: Gynecological cancer represents a significant global health challenge, and conventional treatment modalities have demonstrated limited efficacy. However, recent investigations into immune checkpoint pathways have unveiled promising opportunities for ... ...

    Abstract Gynecological cancer represents a significant global health challenge, and conventional treatment modalities have demonstrated limited efficacy. However, recent investigations into immune checkpoint pathways have unveiled promising opportunities for enhancing the prognosis of patients with cancer. Among these pathways, TIGIT has surfaced as a compelling candidate owing to its capacity to augment the immune function of NK and T cells through blockade, thereby yielding improved anti-tumor effects and prolonged patient survival. Global clinical trials exploring TIGIT blockade therapy have yielded promising preliminary findings. Nevertheless, further research is imperative to comprehensively grasp the potential of TIGIT-based immunotherapy in optimizing therapeutic outcomes for gynecological cancers. This review primarily delineates the regulatory network and immunosuppressive mechanism of TIGIT, expounds upon its expression and therapeutic potential in three major gynecological cancers, and synthesizes the clinical trials of TIGIT-based cancer immunotherapy. Such insights aim to furnish novel perspectives and serve as reference points for subsequent research and clinical application targeting TIGIT in gynecological cancers.
    MeSH term(s) Humans ; Immunotherapy ; Receptors, Immunologic ; T-Lymphocytes ; Genital Neoplasms, Female/therapy
    Chemical Substances Receptors, Immunologic ; TIGIT protein, human
    Language English
    Publishing date 2024-02-07
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 391889-0
    ISSN 1618-0631 ; 0344-0338
    ISSN (online) 1618-0631
    ISSN 0344-0338
    DOI 10.1016/j.prp.2024.155202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud III Zs.20: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Comparison of Health Care Utilization in Different Usual Sources of Care Among Older People With Cardiovascular Disease in China: Evidence From the Study on Global Ageing and Adult Health.

    Xu, Tiange / Loban, Ekaterina / Wei, Xiaolin / Zhou, Zhongliang / Wang, Wenhua

    International journal of public health

    2024  Volume 68, Page(s) 1606103

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Aged ; Humans ; Middle Aged ; Cardiovascular Diseases/therapy ; Cardiovascular Diseases/epidemiology ; China ; Cross-Sectional Studies ; Delivery of Health Care ; Patient Acceptance of Health Care
    Language English
    Publishing date 2024-01-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2274130-6
    ISSN 1661-8564 ; 1661-8556
    ISSN (online) 1661-8564
    ISSN 1661-8556
    DOI 10.3389/ijph.2023.1606103
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 843: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Potential roles of

    Li, Nan / Meng, Jinxin / He, Yuwen / Wang, Wenhua / Wang, Jinglin

    Frontiers in cellular and infection microbiology

    2024  Volume 13, Page(s) 1283216

    Abstract: Introduction: Culicoides: Methods: The midges were collected from cattle (: Results: A total of 6,300 : Conclusion: The study reveals variations in the species distribution, community composition, blood sucking rate, and blood-feeding sources ... ...

    Abstract Introduction: Culicoides
    Methods: The midges were collected from cattle (
    Results: A total of 6,300
    Conclusion: The study reveals variations in the species distribution, community composition, blood sucking rate, and blood-feeding sources of
    MeSH term(s) Sheep ; Humans ; Cattle ; Animals ; Ceratopogonidae ; Bluetongue virus/genetics ; Phylogeny ; Bluetongue ; China ; Chickens ; Goats
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1283216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Variance, norms and cooperative behavior in public goods games.

    Wang, Guangrong / Li, Jianbiao / Wang, Wenhua / Wang, Yue / Wang, Jiafeng

    Frontiers in psychology

    2024  Volume 15, Page(s) 1277707

    Abstract: This study examines the relationship between the variance of others' contributions, social norms (empirical and normative expectations), and cooperative behavior using a classic linear public goods game. The following results are observed. First, the ... ...

    Abstract This study examines the relationship between the variance of others' contributions, social norms (empirical and normative expectations), and cooperative behavior using a classic linear public goods game. The following results are observed. First, the variance of a participant's group members' contributions had a negative impact on their contributions, empirical expectations, and normative expectations. Second, deviations from the mean, whether negative or positive, were deemed less socially appropriate. Third, while there was a strong relationship between variance, social norms, and cooperative behavior, the mediating effect of social norms was found to be insignificant. Finally, there were some notable findings regarding behavior type. Although free riders and cooperators exhibited distinct behavioral patterns, their normative expectations were similar. Free riders expected others to cooperate, but their empirical expectations were significantly lower than cooperators' expectations, which were aligned with their actual contributions. These findings contribute to research on the relationship between distribution heterogeneity, social norms and cooperative behavior. Furthermore, these findings provide valuable insights into management practices.
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2024.1277707
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  8. Article ; Online: Confusion cannot explain cooperative behavior in public goods games.

    Wang, Guangrong / Li, Jianbiao / Wang, Wenhua / Niu, Xiaofei / Wang, Yue

    Proceedings of the National Academy of Sciences of the United States of America

    2024  Volume 121, Issue 10, Page(s) e2310109121

    Abstract: Some scholars find that behavioral variation in the public goods game is explained by variations in participants' understanding of how to maximize payoff and that confusion leads to cooperation. Their findings lead them to question the common assumption ... ...

    Abstract Some scholars find that behavioral variation in the public goods game is explained by variations in participants' understanding of how to maximize payoff and that confusion leads to cooperation. Their findings lead them to question the common assumption in behavioral economics experiments that choices reflect motivations. We conduct two experiments, in which we minimize confusion by providing participants with increased training. We also introduce a question that specifically assesses participants' understanding of payoff maximization choices. Our experimental results show that the distribution of behavior types is significantly different when participants play with computers versus humans. A significant increase in contributions is also observed when participants play with humans compared to when they play with computers. Moreover, social norms may be the main motive for contributions when playing with computers. Our findings suggest that social preferences, rather than confusion, play a crucial role in determining contributions in public goods games when playing with humans. We therefore argue that the assumption in behavioral economics experiments that choices reveal motivations is indeed valid.
    MeSH term(s) Humans ; Cooperative Behavior ; Economics, Behavioral ; Game Theory
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2310109121
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Patient views of the good doctor in primary care: a qualitative study in six provinces in China.

    Wang, Wenhua / Zhang, Jinnan / Lu, Jiao / Wei, Xiaolin

    Global health research and policy

    2023  Volume 8, Issue 1, Page(s) 24

    Abstract: Background: China has been striving to train primary care doctors capable of delivering high-quality service through general practitioner training programs and family doctor team reforms, but these initiatives have not adequately met patient needs and ... ...

    Abstract Background: China has been striving to train primary care doctors capable of delivering high-quality service through general practitioner training programs and family doctor team reforms, but these initiatives have not adequately met patient needs and expectations. In order to guide further reform efforts to better meet patient expectations, this study generates a profile of the good doctor in primary care from the patient perspective.
    Methods: Semi-structured interviews were conducted in six provinces (Shandong, Zhejiang, Henan, Shaanxi, Shanxi, Heilongjiang) in China. A total of 58 interviewees completed the recorded interviews. Tape-based analysis was used to produce narrative summaries. Trained research assistants listened to the recordings of the interviews and summarized them by 30-s segments. Thematic analysis was performed on narrative summaries to identify thematic families.
    Results: Five domains and 18 attributes were generated from the analysis of the interview data. The domains of the good doctor in primary care from the patient perspective were: strong Clinical Competency (mentioned by 97% of participants) and Professionalism & Humanism (mentioned by 93% of participants) during service delivery, followed by Service Provision and Information Communication (mentioned by 74% and 62% of participants, respectively). Moreover, Chinese patients expect that primary care doctors have high educational attainment and a good personality (mentioned by 41% of participants).
    Conclusions: This five-domain profile of the good doctor in primary care constitutes a foundation for further primary care workforce capacity building. Further primary care reform efforts should reflect the patient views and expectations, especially in the family physician competency framework and primary care performance assessment system development. Meanwhile, frontline primary care organizations also need to create supportive environments to assist competent doctors practice in primary care, especially through facilitating the learning of primary care doctors and improving their well-being.
    MeSH term(s) Humans ; Physicians, Family ; General Practitioners ; China ; Qualitative Research ; Primary Health Care
    Language English
    Publishing date 2023-07-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2397-0642
    ISSN (online) 2397-0642
    DOI 10.1186/s41256-023-00309-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Sepsis associated with acute lung injury over the period 2012-2021: a bibliometric analysis.

    Liang, Guibin / Wang, Wenhua / He, Zhihui

    Frontiers in physiology

    2023  Volume 14, Page(s) 1079736

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-06-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1079736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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