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  1. Article ; Online: External application of chicken eggs on delayed healing of tendon bone in mice with rotator cuff injury.

    Zhang, Xingxing / Ren, Hao / Shi, Chuankai / Wang, Xian-Pei / Zhang, Qing / Xiang, Ming

    Minerva surgery

    2024  

    Language English
    Publishing date 2024-01-22
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3067899-7
    ISSN 2724-5438
    ISSN (online) 2724-5438
    DOI 10.23736/S2724-5691.23.10016-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Infrared spectroscopy analysis of SF6 using multiscale weighted principal component analysis].

    Peng, Xi / Wang, Xian-Pei / Huang, Yun-Guang

    Guang pu xue yu guang pu fen xi = Guang pu

    2012  Volume 32, Issue 6, Page(s) 1535–1540

    Abstract: Infrared spectroscopy analysis of SF6 and its derivative is an important method for operating state assessment and fault diagnosis of the gas insulated switchgear (GIS). Traditional methods are complicated and inefficient, and the results can vary with ... ...

    Abstract Infrared spectroscopy analysis of SF6 and its derivative is an important method for operating state assessment and fault diagnosis of the gas insulated switchgear (GIS). Traditional methods are complicated and inefficient, and the results can vary with different subjects. In the present work, the feature extraction methods in machine learning are recommended to solve such diagnosis problem, and a multiscale weighted principal component analysis method is proposed. The proposed method combines the advantage of standard principal component analysis and multiscale decomposition to maximize the feature information in different scales, and modifies the importance of the eigenvectors in classification. The classification performance of the proposed method was demonstrated to be 3 to 4 times better than that of the standard PCA for the infrared spectra of SF6 and its derivative provided by Guangxi Research Institute of Electric Power.
    Language Chinese
    Publishing date 2012-06
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1000-0593
    ISSN 1000-0593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Expression of tissue factor in rabbit pulmonary artery in an acute pulmonary embolism model.

    Zhang, Jing-Xia / Chen, Yong-Li / Zhou, Yu-Ling / Guo, Qian-Yu / Wang, Xian-Pei

    World journal of emergency medicine

    2014  Volume 5, Issue 2, Page(s) 144–147

    Abstract: Background: Tissue factor (TF) is the initiation factor of the extrinsic coagulation pathway, and plays a critical role in the process of thrombosis. This study aimed to investigate the expression of TF and to explore their clinical effect on the ... ...

    Abstract Background: Tissue factor (TF) is the initiation factor of the extrinsic coagulation pathway, and plays a critical role in the process of thrombosis. This study aimed to investigate the expression of TF and to explore their clinical effect on the pulmonary artery after acute pulmonary thromboembolism.
    Methods: Thirty-four Japanese white rabbits (Level II animals) supplied by Tianjin Medical University were randomly assigned into: group A, specimens of the pulmonary artery taken 3 hours after pulmonary embolism (n=8); group B, specimens of the pulmonary artery taken 8 hours after pulmonary embolism (n=8); group C, specimens of the pulmonary artery taken 24 hours after pulmonary embolism (n=8); and control group, pseudo-operations performed without injection of autologous blood clots (n=10). The animal model of pulmonary thrombo-embolism was established by injection of autologous blood clots into the jugular vein through a 5F catheter, and was confirmed by digital subtraction angiography. The mRNA expression of TF in different parts of the pulmonary artery was accessed by RT-PCR. The q test was used if there was a significant difference in a given continuous variable among the three groups assessed by ANOVA. The experiment equipment was supplied by the State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, the Chinese Academy of Medical Sciences and Peking Union Medical College.
    Results: The TF expression in the specimen adjacent to emboli was stable at 3, 8 or 24 hours after embolism. The mRNA expression of TF at 3 and 8 hours after embolism was lower in the specimens taken from the distal end of the morbid pulmonary artery than those adjacent to emboli. While at 24 hours after embolism, there were similar mRNA levels in specimens either adjacent or distal to emboli.
    Conclusion: The high level of TF expression in pulmonary artery tissue adjacent to emboli could lead to locally increased coagulation activity, indicating the necessity of initiating anti- coagulation treatment as soon as possible after acute pulmonary embolism.
    Language English
    Publishing date 2014-09-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 2753264-1
    ISSN 1920-8642
    ISSN 1920-8642
    DOI 10.5847/wjem.j.1920-8642.2014.02.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Research on infrared spectrum intercomparison search method based on wavelet multi-scale decomposition].

    Du, Shuang-yu / Wang, Xian-pei / Cai, Tao / Yang, Jie

    Guang pu xue yu guang pu fen xi = Guang pu

    2011  Volume 31, Issue 5, Page(s) 1262–1265

    Abstract: Spectrum intercomparison search means calculating the similarity of question spectrum and standard spectrum in the database to find the same or similar spectrum as the question spectrum. To weaken the impact of irrelevant information on spectrum ... ...

    Abstract Spectrum intercomparison search means calculating the similarity of question spectrum and standard spectrum in the database to find the same or similar spectrum as the question spectrum. To weaken the impact of irrelevant information on spectrum intercomparison search results and improve the search accuracy, the question spectrum noise is taken for example and the impact of spectrum noise on the calculated similarity results is analyzed; for the characteristics that when infrared spectrum is multi-scale decomposed, the useful information is mainly concentrated in the low-frequency part and the high-frequency part is mainly noise, the infrared spectrum intercomparison search method based on wavelet multi-scale decomposition is proposed; the impact of spectrum decomposition level on the calculated similarity results is analyzed; the entire waveform search method is used as reference method and the search program of both methods is designed with MATLAB 7.0 and the feasibility of infrared spectrum intercomparison search method based on wavelet multi-scale decomposition is confirmed by the experimental results.
    Language Chinese
    Publishing date 2011-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1000-0593
    ISSN 1000-0593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Research on Denoising Ultraviolet Spectrum Signal with An Improved Effective Singular Value Selection Method].

    Dai, Dang-dang / Wang, Xian-pei / Zhao, Yu / Tian, Meng / Long, Jia-chuan / Zhu, Guo-wei / Zhang, Long-fei

    Guang pu xue yu guang pu fen xi = Guang pu

    2016  Volume 36, Issue 7, Page(s) 2139–2143

    Abstract: Spectrum denoising is an important part of spectrum detection. As we know, spectral signal is susceptible to thermal noise, mechanical vibration on site and random noise, etc. However, online monitoring systems require to reduce the impact of parameter ... ...

    Abstract Spectrum denoising is an important part of spectrum detection. As we know, spectral signal is susceptible to thermal noise, mechanical vibration on site and random noise, etc. However, online monitoring systems require to reduce the impact of parameter selection caused by human operation on denoising, so a method based on singular value decomposition is proposed to denoise spectrum signal. An improved effective singular value selection method is also proposed. First, the author specify the maximum peak of the difference spectrum of singular value for the lower bound which named θ1, using the integrated information of singular value and its difference spectrum to select the upper bound, which is called θ2. The interval θ1~θ2 is defined as a fuzzy area. Then, the membership is obtained with Fuzzy C-means clusting and corresponding weight coefficients to the singular values in the fuzzy area are given. Finally, the proposed method is used to denoise UV spectrum signal with different signal to noise ratio. The signal to noise ratio, root mean square error, normalied correlation coefficient and smoothness radio are used to evaluate the result of denoising. The result shows that: based on data-driven, the proposed method has a good denoising effect, which can effectively restore the original signal.
    Language Chinese
    Publishing date 2016-07
    Publishing country China
    Document type Journal Article
    ISSN 1000-0593
    ISSN 1000-0593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Infrared spectrum analysis of SF6 and SF6 decomposition].

    Cai, Tao / Wang, Xian-pei / Huang, Yun-guang / Du, Shuang-yu

    Guang pu xue yu guang pu fen xi = Guang pu

    2010  Volume 30, Issue 11, Page(s) 2967–2970

    Abstract: Pressured SF6 gas is widely used in GIS for electrical insulation as well as for are extinction. And a chemical way for detecting the SF6 and its byproducts is a powerful diagnosis method for GIS. The present paper analyzes the decomposition of insulated ...

    Abstract Pressured SF6 gas is widely used in GIS for electrical insulation as well as for are extinction. And a chemical way for detecting the SF6 and its byproducts is a powerful diagnosis method for GIS. The present paper analyzes the decomposition of insulated gas of GIS (mostly SF6) in three cases with infrared spectrometer. As a result, it was found that the content of S2F10 can be used to decide whether spark or arc discharge leads to the fall down of GIS; CF4 can be used for judging the insulation grade of GIS. Besides, the gas leakage of the GIS should be concerned in the long lifetime of GIS. Finally, it is supposed that a data base containing the history of results from the gas diagnostics for each piece of equipment should be created for future maintenance activities.
    Language Chinese
    Publishing date 2010-11
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1000-0593
    ISSN 1000-0593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Baseline correction method for spectrum signal of SF6 insulating air with optimum wavelet basis].

    Liu, Yan / Liu, Kai / Tao, Wei-Liang / Wang, Xian-Pei

    Guang pu xue yu guang pu fen xi = Guang pu

    2010  Volume 30, Issue 6, Page(s) 1688–1691

    Abstract: SF6 gas has been widely used in the power equipments as an excellent electric insulating and arc-quenching medium. In the present paper, a baseline correction method based on the optimum wavelet basis for spectrum detection is proposed to measure the ... ...

    Abstract SF6 gas has been widely used in the power equipments as an excellent electric insulating and arc-quenching medium. In the present paper, a baseline correction method based on the optimum wavelet basis for spectrum detection is proposed to measure the composition content of the SF6 insulating gas to secure the power safety. In this method, the optimum wavelet basis is selected in the wavelet packet according to constructor function on the energy concentration criterion to express the spectrum signal in the time-frequency domain. Then the strong spectrum composition is removed from the spectrum signal with the threshold method to eliminate the interference with the continuous spectrum fitting. Finally we remove the continuous spectrum which is fitting result from the origin spectrum and obtain the useful signal of line spectrum. The intensities of spectral line processed with the proposed algorithm could reflect the concentration of the conponents to be measured in SF6 gas. Experiments to analyze the absorption spectrum of the SF6 insulating gas mixture show that the proposed algorithm can estimate and correct the drifting baseline accurately, and its performance is better than the algorithm based on iterative wavelet.
    Language Chinese
    Publishing date 2010-06
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1000-0593
    ISSN 1000-0593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Early warning for various internal faults of GIS based on ultraviolet spectroscopy].

    Zhao, Yu / Wang, Xian-pei / Hu, Hong-hong / Dai, Dang-dang / Long, Jia-chuan / Tian, Meng / Zhu, Guo-wei / Huang, Yun-guang

    Guang pu xue yu guang pu fen xi = Guang pu

    2015  Volume 35, Issue 2, Page(s) 438–442

    Abstract: As the basis of accurate diagnosis, fault early-warning of gas insulation switchgear (GIS) focuses on the time-effectiveness and the applicability. It would be significant to research the method of unified early-warning for partial discharge (PD) and ... ...

    Abstract As the basis of accurate diagnosis, fault early-warning of gas insulation switchgear (GIS) focuses on the time-effectiveness and the applicability. It would be significant to research the method of unified early-warning for partial discharge (PD) and overheated faults in GIS. In the present paper, SO2 is proposed as the common and typical by-product. The unified monitoring could be achieved through ultraviolet spectroscopy (UV) detection of SO2. The derivative method and Savitzky-Golay filtering are employed for baseline correction and smoothing. The wavelength range of 290-310 nm is selected for quantitative detection of SO2. Through UV method, the spectral interference of SF6 and other complex by-products, e.g., SOF2 and SOF2, can be avoided and the features of trace SO2 in GIS can be extracted. The detection system is featured by compacted structure, low maintenance and satisfactory suitability in filed surveillance. By conducting SF6 decomposition experiments, including two types of PD faults and the overheated faults between 200-400 degrees C, the feasibility of proposed UV method has been verified. Fourier transform infrared spectroscopy and gas chromatography methods can be used for subsequent fault diagnosis. The different decomposition features in two kinds of faults are confirmed and the diagnosis strategy has been briefly analyzed. The main by-products under PD are SOF2 and SO2F2. The generated SO2 is significantly less than SOF2. More carbonous by-products will be generated when PD involves epoxy. By contrast, when the material of heater is stainless steel, SF6 decomposes at about 300 "C and the main by-products in overheated faults are SO2 and SO2F2. When heated over 350 degrees C, SO2 is generated much faster. SOz content stably increases when the GIS fault lasts. The faults types could be preliminarily identified based on the generation features of SO2.
    Language Chinese
    Publishing date 2015-02
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1000-0593
    ISSN 1000-0593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Effect of Kv1.3 and KCa3.1 potassium ion channels on the proliferation and migration of monocytes/macrophages].

    Zhang, Shuang-Xia / Wang, Xian-Pei / Gao, Chuan-Yu / Ju, Chen-Hui / Zhu, Li-Jie / DU, Yi-Mei

    Sheng li xue bao : [Acta physiologica Sinica

    2015  Volume 67, Issue 5, Page(s) 505–512

    Abstract: This study was aimed to investigate the effects of blockade of Ca(2+) activated channel KCa3.1 and voltage-gated potassium channel Kv1.3 of the monocytes/macrophages on inflammatory monocyte chemotaxis. Chemotaxis assay was used to test the inflammatory ... ...

    Abstract This study was aimed to investigate the effects of blockade of Ca(2+) activated channel KCa3.1 and voltage-gated potassium channel Kv1.3 of the monocytes/macrophages on inflammatory monocyte chemotaxis. Chemotaxis assay was used to test the inflammatory Ly-6C(hi) monocyte chemotaxis caused by the monocytes/macrophages. The proliferation of monocytes/macrophages was detected by cell counting kit-8 (CCK8). Enzyme-linked immunosorbent assay (ELISA) was applied to detect the C-C motif ligand 7 (CCL7) in cultured media. The results showed that the recruitment of Ly-6C(hi) monocyte induced by monocytes/macrophages was suppressed by the potent Kv1.3 blocker Stichodactyla helianthus neurotoxin (ShK) or the specific KCa3.1 inhibitor TRAM-34. Meanwhile, the proliferation of monocytes/macrophages was significantly inhibited by ShK. The response of Ly-6C(hi) monocyte pretreated with ShK or TRAM-34 to CCL2 was declined. These results suggest that KCa3.1 and Kv1.3 may play an important role in monocytes/macrophages' proliferation and migration.
    MeSH term(s) Cell Movement ; Cell Proliferation ; Cnidarian Venoms/pharmacology ; Enzyme-Linked Immunosorbent Assay ; Humans ; Kv1.3 Potassium Channel/antagonists & inhibitors ; Kv1.3 Potassium Channel/physiology ; Macrophages/cytology ; Monocytes/cytology ; Protein Structure, Tertiary ; Pyrazoles/pharmacology ; Small-Conductance Calcium-Activated Potassium Channels/antagonists & inhibitors ; Small-Conductance Calcium-Activated Potassium Channels/physiology
    Chemical Substances Cnidarian Venoms ; KCNN3 protein, human ; Kv1.3 Potassium Channel ; Pyrazoles ; Small-Conductance Calcium-Activated Potassium Channels ; TRAM 34 ; neurotoxin I, Stichodactyla helianthus (117860-13-6)
    Language Chinese
    Publishing date 2015-10-25
    Publishing country China
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604308-2
    ISSN 0371-0874
    ISSN 0371-0874
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Blockade of KCa3.1 Attenuates Left Ventricular Remodeling after Experimental Myocardial Infarction.

    Ju, Chen-Hui / Wang, Xian-Pei / Gao, Chuan-Yu / Zhang, Shuang-Xia / Ma, Xing-Hua / Liu, Chang

    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

    2015  Volume 36, Issue 4, Page(s) 1305–1315

    Abstract: Background/aims: After myocardial infarction (MI), cardiac fibrosis greatly contributes to left ventricular remodeling and heart failure. The intermediate-conductance calcium-activated potassium Channel (KCa3.1) has been recently proposed as an ... ...

    Abstract Background/aims: After myocardial infarction (MI), cardiac fibrosis greatly contributes to left ventricular remodeling and heart failure. The intermediate-conductance calcium-activated potassium Channel (KCa3.1) has been recently proposed as an attractive target of fibrosis. The present study aimed to detect the effects of KCa3.1 blockade on ventricular remodeling following MI and its potential mechanisms.
    Methods: Myocardial expression of KCa3.1 was initially measured in a mouse MI model by Western blot and real time-polymerase chain reaction. Then after treatment with TRAM-34, a highly selective KCa3.1 blocker, heart function and fibrosis were evaluated by echocardiography, histology and immunohistochemistry. Furthermore, the role of KCa3.1 in neonatal mouse cardiac fibroblasts (CFs) stimulated by angiotensin II (Ang II) was tested.
    Results: Myocardium expressed high level of KCa3.1 after MI. Pharmacological blockade of KCa3.1 channel improved heart function and reduced ventricular dilation and fibrosis. Besides, a lower prevalence of myofibroblasts was found in TRAM-34 treatment group. In vitro studies KCa3.1 was up regulated in CFs induced by Ang II and suppressed by its blocker.KCa3.1 pharmacological blockade attenuated CFs proliferation, differentiation and profibrogenic genes expression and may regulating through AKT and ERK1/2 pathways.
    Conclusion: Blockade of KCa3.1 is able to attenuate ventricular remodeling after MI through inhibiting the pro-fibrotic effects of CFs.
    MeSH term(s) Animals ; Cells, Cultured ; Collagen/analysis ; Fibroblasts/drug effects ; Fibroblasts/pathology ; Fibrosis ; Heart/drug effects ; Heart Ventricles/drug effects ; Heart Ventricles/pathology ; Intermediate-Conductance Calcium-Activated Potassium Channels/analysis ; Intermediate-Conductance Calcium-Activated Potassium Channels/antagonists & inhibitors ; Male ; Mice ; Mice, Inbred C57BL ; Myocardial Infarction/drug therapy ; Myocardial Infarction/pathology ; Myocardium/metabolism ; Myocardium/pathology ; Pyrazoles/therapeutic use ; Ventricular Remodeling/drug effects
    Chemical Substances Intermediate-Conductance Calcium-Activated Potassium Channels ; Kcnn4 protein, mouse ; Pyrazoles ; TRAM 34 ; Collagen (9007-34-5)
    Language English
    Publishing date 2015-07-10
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1067572-3
    ISSN 1421-9778 ; 1015-8987
    ISSN (online) 1421-9778
    ISSN 1015-8987
    DOI 10.1159/000430298
    Database MEDical Literature Analysis and Retrieval System OnLINE

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