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Article: [New recognition of portal vein thrombosis mechanism and treatment in cirrhosis].

Wu, Z N / Xiao, Y / Wang, Y D

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

2023 Volume 30, Issue 11, Page(s) 1280–1284

Abstract: Portal vein thrombosis (PVT) is one of the common complications of cirrhosis, which induces or aggravates ascites and upper gastrointestinal bleeding and even impacts the difficulty of liver transplantation by raising portal pressure, hence deteriorating ...

Abstract	Portal vein thrombosis (PVT) is one of the common complications of cirrhosis, which induces or aggravates ascites and upper gastrointestinal bleeding and even impacts the difficulty of liver transplantation by raising portal pressure, hence deteriorating the prognosis of patients. With the revelation of PVT-related research findings in recent years, the recognition of its mechanism and clinical risks has deepened. This article reviews the latest progress in PVT formation mechanisms and treatment strategies to improve clinicians' recognition of the pathogenesis and aid in formulating reasonable prevention and treatment.
MeSH term(s)	Humans ; Portal Vein/pathology ; Liver Cirrhosis/complications ; Liver Cirrhosis/pathology ; Venous Thrombosis/complications ; Liver Transplantation/adverse effects ; Gastrointestinal Hemorrhage/pathology
Language	Chinese
Publishing date	2023-02-27
Publishing country	China
Document type	Review ; English Abstract ; Journal Article
ISSN	1007-3418
ISSN	1007-3418
DOI	10.3760/cma.j.cn501113-20220322-00131
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparison of intravesical chemotherapy regimens after radical nephroureterectomy for upper tract urothelial carcinoma and analysis of risk factors for postoperative recurrence.

Jiang, S-C / Liao, Y-G / Luo, J / Hu, D / Wang, Y-D / He, K

European review for medical and pharmacological sciences

2024 Volume 28, Issue 6, Page(s) 2387–2395

Abstract: Objective: Upper tract urothelial carcinoma (UTUC) is a relatively rare but aggressive type of urologic cancer that includes renal pelvic tumors and ureteral tumors with a poor prognosis. Full-length nephroureterectomy plus sleeve bladder resection is ... ...

Abstract	Objective: Upper tract urothelial carcinoma (UTUC) is a relatively rare but aggressive type of urologic cancer that includes renal pelvic tumors and ureteral tumors with a poor prognosis. Full-length nephroureterectomy plus sleeve bladder resection is the standard treatment for the disease, but patients are prone to recurrence of bladder tumors after surgery. Intravesical infusion therapy is the main means to prevent the recurrence and progression of bladder cancer. Epirubicin and gemcitabine are widely used in clinical practice as first-line or salvage therapy for intravesical chemotherapy; however, the efficacy of these agents is rarely discussed. The purpose of this study was to investigate the effects of epirubicin and gemcitabine on the occurrence of bladder cancer after radical nephroureterectomy for UTUC and to analyze the risk factors affecting the recurrence of postoperative bladder cancer. Patients and methods: A total of 215 patients with diagnosed UTUC and treated in our hospital from June 2019 to August 2021 were retrospectively selected as the research subjects, and they were divided into an observation group (120 cases) and a control group (95 cases) according to different treatment methods. The patients in the control group were treated with epirubicin, while those in the observation group received gemcitabine. All patients were followed up by telephone or outpatient examination for 12 months to record the occurrence of adverse reactions. The occurrence of bladder cancer was recorded at 3 months, 6 months, and 12 months after the surgery. According to the occurrence of bladder cancer after surgery, the patients were divided into a bladder cancer group (63 cases) and a non-bladder cancer group (152 cases). Multivariate Logistic regression analysis was used to analyze the risk factors of bladder cancer after surgery. Results: The total incidence of adverse reactions in the control group was 49.47%, which was higher than that in the observation group with 15.00% (p<0.01). The incidence of bladder tumors in the observation group and the control group was 0.00% and 2.11% at 3 months, 5.00% and 8.42% at 6 months, 13.33% and 15.79% at 12 months, without significant difference (p>0.05). After 12 months of perfusion, the levels of acidic fibroblast growth factor (aFGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF) in the two groups were significantly lower than those before perfusion (p<0.05). In the observation group, the levels of these three factors were slightly decreased compared with those in the control group, without a significant difference (p>0.05). Between the bladder cancer and non-bladder cancer groups, there were significant differences in tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer (p<0.05). The above indexes were all risk factors for postoperative bladder cancer (p<0.05). Conclusions: Epirubicin and gemcitabine reduced the occurrence of bladder cancer and effectively inhibited tumor angiogenesis after radical nephroureterectomy for UTUC. The tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer were risk factors for postoperative bladder cancer.
MeSH term(s)	Humans ; Nephroureterectomy ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/surgery ; Urinary Bladder Neoplasms/pathology ; Carcinoma, Transitional Cell/drug therapy ; Carcinoma, Transitional Cell/surgery ; Retrospective Studies ; Epirubicin/therapeutic use ; Gemcitabine ; Vascular Endothelial Growth Factor A ; Risk Factors ; Neoplasm Recurrence, Local/pathology ; Nephrectomy
Chemical Substances	Epirubicin (3Z8479ZZ5X) ; Gemcitabine ; Vascular Endothelial Growth Factor A
Language	English
Publishing date	2024-04-04
Publishing country	Italy
Document type	Journal Article
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
DOI	10.26355/eurrev_202403_35745
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Article: [Research progress of arginine vasopressin V2 receptor antagonist tolvaptan in the treatment of cirrhotic ascites].

Hu, Y Y / Zhang, X / Wang, Y D / Zhao, C Y

Zhonghua nei ke za zhi

2023 Volume 62, Issue 7, Page(s) 881–884

MeSH term(s)	Humans ; Tolvaptan/therapeutic use ; Ascites/drug therapy ; Receptors, Vasopressin ; Liver Cirrhosis/complications ; Liver Cirrhosis/drug therapy ; Sodium
Chemical Substances	Tolvaptan (21G72T1950) ; Receptors, Vasopressin ; Sodium (9NEZ333N27)
Language	Chinese
Publishing date	2023-07-02
Publishing country	China
Document type	Journal Article
ZDB-ID	754223-9
ISSN	0578-1426
ISSN	0578-1426
DOI	10.3760/cma.j.cn112138-20220630-00488
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Zs.A 1620: Show issues

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Article: [Value of (11)C-PiB PET/MRI in the evaluation of organ involvement in primary systemic light chain amyloidosis].

Wang, Y D / Yang, Y Y / Wu, Y Y / Sun, C Y

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

2022 Volume 43, Issue 4, Page(s) 316–322

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Amyloidosis/diagnostic imaging ; Aniline Compounds ; Humans ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; Retrospective Studies ; Stroke Volume ; Ventricular Function, Left
Chemical Substances	Aniline Compounds
Language	Chinese
Publishing date	2022-06-10
Publishing country	China
Document type	Journal Article
ZDB-ID	2997162-7
ISSN	0253-2727 ; 0253-2727
ISSN (online)	0253-2727
ISSN	0253-2727
DOI	10.3760/cma.j.issn.0253-2727.2022.04.009
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Article: [Early diagnosis and predictive model for hepatitis B virus-related hepatocellular carcinoma].

Yang, S T / Wang, W / Wang, Y D / Zhao, C Y

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

2022 Volume 30, Issue 6, Page(s) 667–671

Abstract: Most hepatocellular carcinoma are diagnosed at an advanced stage and thereby have a high mortality rate. Thus, the key to improving patient prognosis is early diagnosis of hepatocellular carcinoma. In recent years, Asian scholars have summarized a series ...

Abstract	Most hepatocellular carcinoma are diagnosed at an advanced stage and thereby have a high mortality rate. Thus, the key to improving patient prognosis is early diagnosis of hepatocellular carcinoma. In recent years, Asian scholars have summarized a series of hepatocellular carcinoma risk score model for population with chronic hepatitis B, which can help to identify high-risk groups early and improve the early diagnosis rate. This paper briefly analyzes the risk factors and validated risk model for early prediction of hepatitis B virus-related hepatocellular carcinoma, and further reviews the effect of antiviral therapy on the risk of hepatocellular carcinoma.
MeSH term(s)	Antiviral Agents/therapeutic use ; Carcinoma, Hepatocellular/pathology ; Early Diagnosis ; Hepatitis B/drug therapy ; Hepatitis B virus ; Hepatitis B, Chronic/complications ; Hepatitis B, Chronic/drug therapy ; Humans ; Liver Neoplasms/pathology ; Risk Factors
Chemical Substances	Antiviral Agents
Language	Chinese
Publishing date	2022-06-03
Publishing country	China
Document type	Journal Article
ISSN	1007-3418
ISSN	1007-3418
DOI	10.3760/cma.j.cn501113-20190201-00042
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Article: [Incidence and mortality of endometrial cancer in China, data from China Cancer Registry Annual Report, 2004-2017].

Yan, Y / Wang, Y M / Wang, Y D / Mao, W X / Tian, W Y / Xue, F X

Zhonghua yi xue za zhi

2024 Volume 104, Issue 10, Page(s) 721–728

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Humans ; Female ; Middle Aged ; Aged, 80 and over ; Incidence ; Urban Population ; Endometrial Neoplasms/epidemiology ; Rural Population ; Registries ; China/epidemiology ; Genital Neoplasms, Female
Language	Chinese
Publishing date	2024-02-26
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	132513-9
ISSN	0376-2491
ISSN	0376-2491
DOI	10.3760/cma.j.cn112137-20231017-00784
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Book ; Online: Quantum Theory of Nonlinear Thermal Response

Wang, Y. D. / Zhu, Z. G. / Su, G.

2022

Abstract: The Linear behavior of thermal transport has been widely explored, both theoretically and ex?perimentally. On the other hand, the nonlinear thermal response has not been fully discussed. In light of the thermal vector potential theory [Phys. Rev. Lett. ... ...

Abstract	The Linear behavior of thermal transport has been widely explored, both theoretically and ex?perimentally. On the other hand, the nonlinear thermal response has not been fully discussed. In light of the thermal vector potential theory [Phys. Rev. Lett. 114, 196601 (2015)], we develop a general formulation to calculate the linear and nonlinear dynamic thermal responses. In the DC limit, we recover the well-known Mott relation and the Wiedemann-Franz (WF) law at the linear order response, which link the thermoelectric conductivity {\eta}, thermal conductivity \k{appa} and electric conductivity {\sigma} together. To be specific, the linear Mott relation describes the linear {\eta} is proportional to the first derivative of {\sigma} with respect to Fermi energy (for brevity we call the first derivative, the others are similar); and the linear WF law shows the linear \k{appa} is proportional to the zero derivative (i.e. the {\sigma} itself). We found there are higher-order Mott relation and WF law which follow an order-dependent relation. At the second order, the Mott relation indicates that the second order {\sigma} is proportional to the zero derivative of the second order {\eta}; but the second WF law shows that the second {\sigma} is proportional to the first derivative of \k{appa}. At the third order, the derivative order in?creases once. Although we only did explicit calculate up to the third order response, we can deduce that the n-th order electric conductivity is proportional to the n-2-th derivative of the n-th order thermoelectric conductivity for the nonlinear Mott relation; and the n-th order electric conductivity is proportional to the n-1-th derivative of the n-th order thermal conductivity for the nonlinear WF law.
Keywords	Condensed Matter - Statistical Mechanics
Subject code	621
Publishing date	2022-04-19
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Association of SREBF-2 gene polymorphisms with the risk of developing type 2 diabetes mellitus.

Zhang, Y / Sun, X X / Liu, Y C / Wang, Y D

Journal of biological regulators and homeostatic agents

2021 Volume 35, Issue 1, Page(s) 311–314

MeSH term(s)	China ; Diabetes Mellitus, Type 2/genetics ; Genetic Predisposition to Disease ; Humans ; Polymorphism, Genetic ; Polymorphism, Single Nucleotide ; Sterol Regulatory Element Binding Protein 2
Chemical Substances	SREBF2 protein, human ; Sterol Regulatory Element Binding Protein 2
Language	English
Publishing date	2021-04-13
Publishing country	Italy
Document type	Letter
ZDB-ID	639196-5
ISSN	1724-6083 ; 0393-974X
ISSN (online)	1724-6083
ISSN	0393-974X
DOI	10.23812/20-692-L
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Article: [Progress in research of population size estimation by network scale-up method].

Wang, Y D / Zhang, X T / Ma, K F / Li, D M

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

2021 Volume 43, Issue 9, Page(s) 1503–1507

Abstract: Network scale-up method is an indirect population size estimation method based on social network theory. It is widely used in estimating the hidden population size because it does not need to contact the target population. In order to provide reference ... ...

Abstract	Network scale-up method is an indirect population size estimation method based on social network theory. It is widely used in estimating the hidden population size because it does not need to contact the target population. In order to provide reference for the further application of this method, this paper summarizes the traditional network scale-up method, the progress of this method and its combination with new survey techniques.
MeSH term(s)	Humans ; Population Density ; Surveys and Questionnaires
Language	Chinese
Publishing date	2021-05-24
Publishing country	China
Document type	Journal Article
ZDB-ID	645026-x
ISSN	0254-6450
ISSN	0254-6450
DOI	10.3760/cma.j.cn112338-20211130-00925
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Article: [Research Progress on the Role of Mitochondrial DNA in the Pathogenesis of Chronic Liver Disease].

Zhang, X / Hu, Y Y / Luo, Y / Wang, Y D / Zhao, C Y

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

2022 Volume 30, Issue 4, Page(s) 447–451

Abstract: Mitochondrial DNA is the mitochondria's own genetic material located within the mitochondrial matrix and is involved in cellular metabolism and energy supply. Mitochondrial DNA damage exacerbates oxidative stress by increasing the release of reactive ... ...

Abstract	Mitochondrial DNA is the mitochondria's own genetic material located within the mitochondrial matrix and is involved in cellular metabolism and energy supply. Mitochondrial DNA damage exacerbates oxidative stress by increasing the release of reactive oxygen species, while mitochondrial DNA release also triggers apoptosis and activates immune inflammatory responses through damage-related molecular patterns. Mitochondrial autophagy regulates mitochondrial DNA damage and release through a negative feedback mechanism to maintain intracellular homeostasis. Recent studies have shown that the occurrence and development of chronic liver disease are closely related to mitochondrial DNA-mediated immune inflammatory responses and oxidative stress.
MeSH term(s)	Apoptosis ; Autophagy ; DNA, Mitochondrial/genetics ; DNA, Mitochondrial/metabolism ; Humans ; Liver Diseases ; Mitochondria ; Oxidative Stress ; Reactive Oxygen Species/metabolism
Chemical Substances	DNA, Mitochondrial ; Reactive Oxygen Species
Language	Chinese
Publishing date	2022-05-11
Publishing country	China
Document type	Journal Article
ISSN	1007-3418
ISSN	1007-3418
DOI	10.3760/cma.j.cn501113-20210622-00296
Database	MEDical Literature Analysis and Retrieval System OnLINE

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