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  1. Article: [Coronary CT angiography derived fractional flow reserve: view from radiologist].

    Wang, Y N / Xu, C

    Zhonghua yi xue za zhi

    2022  Volume 102, Issue 33, Page(s) 2571–2574

    Abstract: The diagnosis of coronary artery disease depends on a comprehensive assessment including morphological and functional information. Coronary CT angiography derived fractional flow reserve (CT-FFR) could obtain morphological and functional information from ...

    Abstract The diagnosis of coronary artery disease depends on a comprehensive assessment including morphological and functional information. Coronary CT angiography derived fractional flow reserve (CT-FFR) could obtain morphological and functional information from a single coronary CT angiography (CCTA) scan, achieving a "one-stop" assessment of coronary artery disease. CT-FFR is a non-invasive imaging examination to assess the hemodynamic changes of focal coronary lesions and suitable for patients with moderate to severe coronary artery stenosis or mild coronary artery stenosis combined with other high-risk characteristics, to assist in determining whether the lesions cause myocardial ischemia, and to guide clinical decisions and predict the risk of cardiovascular events. The application of CT-FFR relies on satisfied image quality of CCTA, and requires the cooperation of radiologists, clinicians and patients. This paper describes from the aspects of the measurement and analysis of CT-FFR, the diagnostic value of CT-FFR, the value of CT-FFR in assisting clinical decision making and prognosis, the comparison of CT-FFR with other functional cardiovascular imaging techniques and the future perspectives.
    MeSH term(s) Computed Tomography Angiography/methods ; Coronary Artery Disease/diagnostic imaging ; Coronary Stenosis/diagnostic imaging ; Fractional Flow Reserve, Myocardial ; Humans ; Radiologists ; Retrospective Studies ; Tomography, X-Ray Computed
    Language Chinese
    Publishing date 2022-08-12
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20220530-01189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Study on the fit testing for the workers wearing hearing protection device in machinery manufacturing enterprises].

    Wang, Y N / Su, S B / Liao, C H / Zhong, X

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2024  Volume 42, Issue 1, Page(s) 16–21

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Male ; Hearing Loss, Noise-Induced/epidemiology ; Hearing Loss, Noise-Induced/prevention & control ; Ear Protective Devices ; Occupational Diseases/prevention & control ; Hearing ; Noise, Occupational/adverse effects ; Noise, Occupational/prevention & control ; Occupational Exposure/prevention & control
    Language Chinese
    Publishing date 2024-02-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1050900-8
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.cn121094-20220909-00451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Comparison of efficacy between personalized vestibular rehabilitation and otolith reposition for the treatment of atypical benign paroxysmal positional vertigo].

    Lyu, S P / Wang, Y N / Shi, Y H / Gu, L T

    Zhonghua yi xue za zhi

    2024  Volume 104, Issue 14, Page(s) 1138–1142

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Female ; Humans ; Adult ; Middle Aged ; Benign Paroxysmal Positional Vertigo/diagnosis ; Otolithic Membrane ; Treatment Outcome
    Language Chinese
    Publishing date 2024-04-06
    Publishing country China
    Document type Randomized Controlled Trial ; English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20231107-01032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Application of acellular dermal matrix loaded collagen binding domain-vascular endothelial growth factor patch in urethral wound repair in beagles].

    Wang, Y N / Sun, N

    Zhonghua yi xue za zhi

    2021  Volume 101, Issue 36, Page(s) 2900–2905

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Acellular Dermis ; Animals ; Collagen ; Dogs ; Male ; Urethra ; Vascular Endothelial Growth Factor A ; Wound Healing
    Chemical Substances Vascular Endothelial Growth Factor A ; Collagen (9007-34-5)
    Language Chinese
    Publishing date 2021-09-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20210428-01018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [A case report of restrictive hypertrophic cardiomyopathy diagnosed by MRI].

    Wang, Y N / He, J / Zhao, S H / Lu, M J

    Zhonghua xin xue guan bing za zhi

    2023  Volume 51, Issue 9, Page(s) 997–1000

    MeSH term(s) Humans ; Magnetic Resonance Imaging ; Cardiomyopathy, Hypertrophic/diagnostic imaging
    Language Chinese
    Publishing date 2023-08-19
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 603425-1
    ISSN 0253-3758
    ISSN 0253-3758
    DOI 10.3760/cma.j.cn112148-20230807-00056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Opportunities and challenges for doctors in the transformation of medical science and technology achievements in China].

    Li, G X / Wang, Y N

    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

    2020  Volume 23, Issue 6, Page(s) 545–549

    Abstract: The transformation of medical science and technology achievements is of great practical significance for improving the medical standard of our country and promoting the health and well-being of the people. However, China's medical science and technology ... ...

    Abstract The transformation of medical science and technology achievements is of great practical significance for improving the medical standard of our country and promoting the health and well-being of the people. However, China's medical science and technology achievements transformation ecosystem is still immature. Each subject in the system has insufficient cognition of their roles, unclear division of responsibilities, and imperfect system guarantees, resulting in the obstacle of scientific and technological achievements that can truly be transformed into actual productivity. In order to further deepen the understanding and thinking of the current status of China's medical science and technology achievement transformation ecosystem, the opportunities and challenges it faces, to find an optimized path that conforms to the situation in China today, we combine our own production, teaching and research achievement transformation practice, summarize the composition and existing problems of the current system subjects, analyze the plight and outlet of doctors, hoping to provide help and reference for the transformation of scientific and technological achievements to our peer doctors.
    MeSH term(s) Achievement ; Biomedical Research ; Biomedical Technology ; China ; Humans ; Inventions
    Language Chinese
    Publishing date 2020-06-08
    Publishing country China
    Document type Journal Article
    ISSN 1671-0274
    ISSN 1671-0274
    DOI 10.3760/cma.j.cn.441530-20200410-00195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evidence for causal effects of neuropsychiatric conditions on risk for Venous Thromboembolism: a univariable and multivariable Mendelian randomization study.

    Jing, N / Gao, X-T / Ding, H / Wang, Y-N / Zhang, Y-W / Liang, G / Zhu, G-M

    Journal of vascular surgery. Venous and lymphatic disorders

    2024  , Page(s) 101889

    Abstract: Background: Substantial observational evidence suggests an association between neuropsychiatric conditions and Venous Thromboembolism (VTE). However, the causal relationship between these two conditions requires further investigation. Therefore, we ... ...

    Abstract Background: Substantial observational evidence suggests an association between neuropsychiatric conditions and Venous Thromboembolism (VTE). However, the causal relationship between these two conditions requires further investigation. Therefore, we employed a two-sample Mendelian Randomization (MR) approach to assess bidirectional causal effects between four neuropsychiatric conditions and VTE, Deep Vein Thrombosis (DVT), and Pulmonary Embolism (PE).
    Methods: Genetic variants associated with four neuropsychiatric conditions, including Schizophrenia (SCH), Major Depressive Disorder (MDD), Bipolar Disorder (BD), and Epilepsy, as well as VTE, DVT, and PE were selected. Bidirectional univariable and multivariable MR methods were applied to evaluate causal relationships among these conditions. The primary causal estimates were obtained using the Inverse Variance Weighted (IVW) method with multiplicative random effects, supplemented by MR Egger regression, weighted median, simple mode, and weighted mode. Sensitivity analysis was conducted using MR pleiotropy residual sum ,funnel plots and outlier (MR-PRESSO) method.
    Results: Univariable MR results showed that genetic susceptibility to MDD increases the risk of VTE and PE (VTE: OR=1.25, 95%CI: 1.08-1.46, P=0.004; PE: OR=1.36, 95%CI: 1.09-1.69, P=0.006), and PE has an adverse causal effect on MDD (OR=1.02, 95%CI: 1.00-1.04, P=0.026). Adjustment for confounders such as obesity, sleep duration, smoking, physical activity, and alcohol consumption revealed that increased genetic susceptibility to MDD is also associated with VTE and PE.
    Conclusion: Our study suggests that genetic susceptibility to MDD may have an adverse causal effect on the risk of VTE and PE, and PE has a reverse causal effect on MDD. Prevention and early diagnosis of depression are crucial in the management of VTE and PE.
    Language English
    Publishing date 2024-04-13
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2213-3348
    ISSN (online) 2213-3348
    DOI 10.1016/j.jvsv.2024.101889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Clinical characteristics of primary hemophagocytic lymphohistiocytosis associated with perforin gene deficiency: a single-center retrospective study].

    Yu, M Z / Wu, L / Zhang, J / Wang, J S / Wang, Y N / Wang, Z

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2023  Volume 44, Issue 7, Page(s) 572–577

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adult ; Female ; Male ; Humans ; Child, Preschool ; Child ; Adolescent ; Young Adult ; Epstein-Barr Virus Infections/complications ; Epstein-Barr Virus Infections/genetics ; Herpesvirus 4, Human ; Lymphohistiocytosis, Hemophagocytic/genetics ; Perforin/genetics ; Retrospective Studies
    Chemical Substances Perforin (126465-35-8)
    Language Chinese
    Publishing date 2023-09-25
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2023.07.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Enviroment control and healthy education: the most important methods for treatment of allergic rhinitis].

    Wang, H T / Wang, Y N

    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

    2018  Volume 31, Issue 17, Page(s) 1301–1303

    Language Chinese
    Publishing date 2018-06-14
    Publishing country China
    Document type Journal Article
    ISSN 1001-1781
    ISSN 1001-1781
    DOI 10.13201/j.issn.1001-1781.2017.17.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Experimental study on nasal mucosa injury and repair induced by nasal decongestants in guinea pigs].

    Wang, Y N / Wang, H T

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2018  Volume 53, Issue 6, Page(s) 432–439

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Animals ; Chlorpheniramine/adverse effects ; Ephedrine/adverse effects ; Guinea Pigs ; Male ; Mometasone Furoate/therapeutic use ; Naphazoline/adverse effects ; Nasal Decongestants/adverse effects ; Nasal Mucosa/drug effects ; Nasal Mucosa/injuries ; Random Allocation ; Swine
    Chemical Substances Nasal Decongestants ; Mometasone Furoate (04201GDN4R) ; Chlorpheniramine (3U6IO1965U) ; Ephedrine (GN83C131XS) ; Naphazoline (H231GF11BV)
    Language Chinese
    Publishing date 2018-06-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.issn.1673-0860.2018.06.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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