LIVIVO - Search results -

Search results

Result 1 - 10 of total 716

Search options

Article: Innovation or introduction? Impacts of the low-carbon city pilot policy on the pathways toward green technology progress.

Wang, Yanfang / Yao, Jingmin

2024 Volume 10, Issue 7, Page(s) e28745

Abstract: To examine whether the low-carbon city pilot (LCCP) policy influences the green technology innovation (GTI) or embodied technology introduction (ETI), two different pathways to green technology progress, in manufacturing enterprises in China, this study ... ...

Abstract	To examine whether the low-carbon city pilot (LCCP) policy influences the green technology innovation (GTI) or embodied technology introduction (ETI), two different pathways to green technology progress, in manufacturing enterprises in China, this study employs a staggered difference-in-difference (DID) model to evaluate the effects of the policy. The findings suggest that the LCCP policy has stimulated an increase in the quantity of GTI and ETI among enterprises, but reduced the quality of innovation. Large, high-carbon-intensity, and state-owned enterprises are more likely to engage in GTI, while small, low-carbon-intensity, and non-state-owned enterprises prefer ETI. The policy is effective in alleviating financing constraints and improving environmental concerns. Both GTI and ETI play a crucial role in economic performance, while the latter also promotes environmental and ESG performance. Accordingly, we recommend establishing a policy-compatible evaluation system, strengthening mandatory and incentive measures, and cultivating a green innovation ecosystem, etc., to improve the performance of the LCCP policy.
Language	English
Publishing date	2024-03-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e28745
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Knockdown of IFIT3 ameliorates multiple sclerosis via selectively regulating M1 polarization of microglia in an experimental autoimmune encephalomyelitis model.

Sun, Ran / Wang, Yan-Fang / Yang, Xue

International immunopharmacology

2024 Volume 128, Page(s) 111501

Abstract: The key to the treatment of multiple sclerosis (MS) is to promote the transition from inflammation-induced demyelination to remyelination. Polarization of microglia towards M1 or M2 phenotype is critical in this transition. Interferon induced protein ... ...

Abstract	The key to the treatment of multiple sclerosis (MS) is to promote the transition from inflammation-induced demyelination to remyelination. Polarization of microglia towards M1 or M2 phenotype is critical in this transition. Interferon induced protein with tetratricopeptide repeats 3 (IFIT3) is involved in inflammatory reaction and up-regulated in M1-polarized macrophages. However, its effect on microglia during MS has not been reported. In this paper, we demonstrated the important role of IFIT3 in selectively regulating microglia polarization. The expression of IFIT3 was increased when microglia were polarized towards M1, but did not change under M2 polarization. The knockdown of IFIT3 selectively inhibited M1 polarization, while M2 polarization was not affected by IFIT3 silencing. Furthermore, the activation of signal transducer and activator of transcription 1 (STAT1) and nuclear factor kappa-B (NF-ĸB) signaling in M1 polarized microglia was suppressed by downregulating IFIT3. In experimental autoimmune encephalitis (EAE) mice, an animal model of MS, IFIT3 expression was upregulated. The disease progression, inflammatory infiltration and demyelination in the EAE mice were alleviated by silencing IFIT3. The inhibitory effects of IFIT3 knockdown on M1 polarization and STAT1 and NF-ĸB pathways were also confirmed in the spinal cord of EAE mice. In summary, our findings suggest that IFIT3 selectively intensified microglia polarization towards the pro-inflammatory M1 phenotype, and may contribute to the progression of MS.
MeSH term(s)	Animals ; Mice ; Encephalomyelitis, Autoimmune, Experimental ; Inflammation/metabolism ; Mice, Inbred C57BL ; Microglia/metabolism ; Multiple Sclerosis/metabolism ; NF-kappa B/metabolism
Chemical Substances	NF-kappa B ; Ifit3 protein, mouse
Language	English
Publishing date	2024-01-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2043785-7
ISSN	1878-1705 ; 1567-5769
ISSN (online)	1878-1705
ISSN	1567-5769
DOI	10.1016/j.intimp.2024.111501
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5408: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Correction to: Complex network analysis of carbon emission transfers under global value chains.

Wang, Yanfang / Yao, Jingmin

Environmental science and pollution research international

2022 Volume 29, Issue 43, Page(s) 65886

Language	English
Publishing date	2022-07-18
Publishing country	Germany
Document type	Published Erratum
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-22085-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 5915: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Complex network analysis of carbon emission transfers under global value chains.

Wang, Yanfang / Yao, Jingmin

Environmental science and pollution research international

2022 Volume 29, Issue 31, Page(s) 47673–47695

Abstract: Accompanied with the increasing complicated global value chain (GVC) networks is the carbon emission transfers among countries. Utilizing the complex network analysis alongside quadratic assignment procedure (QAP), this paper detects the community ... ...

Abstract	Accompanied with the increasing complicated global value chain (GVC) networks is the carbon emission transfers among countries. Utilizing the complex network analysis alongside quadratic assignment procedure (QAP), this paper detects the community structure and influencing forces of the emission transfers under GVCs. The results imply that the bipolar structure of the network transformed gradually to tripolar owing largely to the surging of carbon emissions from China. Evidence on the existence of environmental Kuznets curve (EKC) in the emission transfers from high-income countries to low-income countries, and a U-shape relationship transfers in the reverse direction, suggesting that growing carbon emissions from both low- and high-income countries transferred to other high-income countries gradually. Gaps in technology, especially in patent applications, between source and destination countries played an important role therein.
MeSH term(s)	Carbon/analysis ; Carbon Dioxide/analysis ; China ; Economic Development ; Income ; Technology
Chemical Substances	Carbon Dioxide (142M471B3J) ; Carbon (7440-44-0)
Language	English
Publishing date	2022-02-19
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-19215-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 5915: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article: Rare NUP98::PRRX1 fusion transcript in a therapy-related acute myeloid leukemia associated with del(7q) following chemotherapy for diffuse large B-cell lymphoma.

Wang, Yanfang / Zhang, Zhenhao / Wang, Lingli / Wang, Hua / Dong, Fei

Cancer genetics

2024 Volume 284-285, Page(s) 12–15

Abstract: Background: Therapy-related acute myeloid leukemia (t-AML) is increasingly recognized as a treatment complication in patients receiving chemotherapy, radiotherapy, or immunosuppressive agents for primary neoplasms. NUP98::PRRX1 fusion gene, caused by t( ... ...

Abstract	Background: Therapy-related acute myeloid leukemia (t-AML) is increasingly recognized as a treatment complication in patients receiving chemotherapy, radiotherapy, or immunosuppressive agents for primary neoplasms. NUP98::PRRX1 fusion gene, caused by t(1;11)(q23;p15), is a rare recurrent cytogenetic alteration in leukemia, and only seven cases with NUP98::PRRX1 were reported so far. Methods: A 53-year-old female patient was diagnosed with t-AML after 20 months of complete remission (CR) from diffuse large B-cell lymphoma (DLBCL). Conventional karyotype, fluorescence in situ hybridization (FISH), and DNA/RNA next-generation sequence (NGS) were used to detect genetic abnormalities. Results: Abnormal karyotype of 46, XX, t(1;11)(q25;p15), del(7)(q22) was revealed. NUP98 gene rearrangement and del(7)(q22) were verified by FISH. Further, RNA NGS detected NUP98::PRRX1 fusion transcript, and DNA NGS detected KRAS gene mutation. The patient achieved CR after a combined chemotherapy regimen containing BCL-2 inhibitor and underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT), but she died of leukemia recurrence 14 months later. Conclusions: Novel targeted drugs may provide opportunities for patients with NUP98::PRRX1 to undergo allo-HSCT. However, since the cases of carrying the NUP98::PRRX1 are limited, more patients with this genetic change need to be investigated to elucidate the prognostic significance.
Language	English
Publishing date	2024-03-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2599227-2
ISSN	2210-7762
ISSN	2210-7762
DOI	10.1016/j.cancergen.2024.03.004
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1521: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Complex network analysis of carbon emission transfers under global value chains

Wang, Yanfang / Yao, Jingmin

Environmental science and pollution research. 2022 July, v. 29, no. 31

2022

Abstract	Accompanied with the increasing complicated global value chain (GVC) networks is the carbon emission transfers among countries. Utilizing the complex network analysis alongside quadratic assignment procedure (QAP), this paper detects the community structure and influencing forces of the emission transfers under GVCs. The results imply that the bipolar structure of the network transformed gradually to tripolar owing largely to the surging of carbon emissions from China. Evidence on the existence of environmental Kuznets curve (EKC) in the emission transfers from high-income countries to low-income countries, and a U-shape relationship transfers in the reverse direction, suggesting that growing carbon emissions from both low- and high-income countries transferred to other high-income countries gradually. Gaps in technology, especially in patent applications, between source and destination countries played an important role therein.
Keywords	carbon ; community structure ; environmental Kuznets curve ; pollution ; research ; supply chain ; China
Language	English
Dates of publication	2022-07
Size	p. 47673-47695.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-19215-w
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 5915: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A 3-4 h oocyte retrieval-ICSI interval optimizes clinical outcomes for women over 40 years.

Chen, Jingbo / Wang, Yanfang / Fang, Cong / Li, Tingting

Scientific reports

2023 Volume 13, Issue 1, Page(s) 15035

Abstract: To explore an appropriate time interval between oocyte retrieval and intracytoplasmic sperm injection (ICSI) for optimal embryological and clinical outcomes in ICSI cycles over 40 years of maternal age. A retrospective analysis of 1476 ICSI fresh cycles ... ...

Abstract	To explore an appropriate time interval between oocyte retrieval and intracytoplasmic sperm injection (ICSI) for optimal embryological and clinical outcomes in ICSI cycles over 40 years of maternal age. A retrospective analysis of 1476 ICSI fresh cycles from women aged over 40 years, was performed at the Reproduction Medicine Research Center of the Sixth Affiliated Hospital of Sun Yat-sen University, between December 2013 and August 2020. The fertilization rate and clinical pregnancy rate were the main outcomes. Multivariate linear regression and logistic regression analysis of factors showed that fertilization rate (P = 0.024) and clinical pregnancy rate (P = 0.011) were significantly associated with oocyte pick up (OPU)-ICSI interval. A longer OPU-ICSI interval (no more than 6 h) was associated with a higher fertilization rate but significantly decreased the clinical pregnancy rate when the OPU-ICSI interval was over 4 h (P < 0.05). The optimal OPU-ICSI interval is between 3 and 4 h for excellent embryological and clinical outcomes in ICSI cycles over 40 years of maternal age.
MeSH term(s)	Male ; Pregnancy ; Humans ; Female ; Adult ; Middle Aged ; Oocyte Retrieval ; Retrospective Studies ; Semen ; Sperm Injections, Intracytoplasmic ; Hospitals
Language	English
Publishing date	2023-09-12
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-41397-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Prognostic value of prior malignancy history in stage I differentiated thyroid cancer: a SEER-based study.

Wang, Yanfang / Li, Shiying / Xu, Fang / Hao, Qing

Translational cancer research

2023 Volume 12, Issue 5, Page(s) 1241–1253

Abstract: Background: Thyroid cancer is the most common endocrine cancer today. Differentiated thyroid cancer (DTC) comprises more than 95% of all thyroid cancers. With the increasing incidence of tumors and development of screening, more patients suffer from ... ...

Abstract	Background: Thyroid cancer is the most common endocrine cancer today. Differentiated thyroid cancer (DTC) comprises more than 95% of all thyroid cancers. With the increasing incidence of tumors and development of screening, more patients suffer from multiple cancers. The purpose of this study was to explore the prognostic value of a history of prior malignancy for stage I DTC. Methods: Stage I DTC patients were identified from the Surveillance, Epidemiology, and End Results (SEER) database. The Kaplan-Meier method and Cox proportional hazards regression method were used to determine the risk factors for overall survival (OS) and disease-specific survival (DSS). A competing risk model was also used to determine the risk factors for DTC-related death after considering the competitive risks. In addition, conditional survival analysis in patients with stage I DTC was performed. Results: A total of 49,723 patients with stage I DTC were enrolled in the study, and 4,982 (10.0%) had prior malignancy history. Prior malignancy history was a factor affecting OS (P<0.001) and DSS (P<0.001) in the Kaplan-Meier analysis and an independent risk factor for OS [hazard ratio (HR) =3.6, 95% confidence interval (CI): 3.17-4.088, P<0.001] and DSS (HR =4.521, 95% CI: 2.224-9.192, P<0.001) in the multivariate Cox proportional hazards regression analysis. In the competing risk model, in the multivariate analysis, prior malignancy history was a risk factor for the DTC-related deaths [subdistribution HR (SHR) =4.32, 95% CI: 2.233-8.3593, P<0.001] after considering the competitive risks. Conditional survival showed that the probability of achieving 5-year DSS was not changed in either the two groups with or without prior malignancy history. For the patients with prior malignancy history, the probability of achieving 5-year OS increased with each additional year survived, but for the patients without prior malignancy history, the improvement of conditional OS only appeared with 2 years already prior survived. Conclusions: Prior malignancy history has an adverse impact on the survival of patients with stage I DTC. The probability of achieving 5-year OS for stage I DTC patients with prior malignancy history increases with each additional year survived. The inconsistent survival effects of prior malignancy history should be considered in clinical trial design and recruitment.
Language	English
Publishing date	2023-04-14
Publishing country	China
Document type	Journal Article
ZDB-ID	2901601-0
ISSN	2219-6803 ; 2218-676X
ISSN (online)	2219-6803
ISSN	2218-676X
DOI	10.21037/tcr-22-2232
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Normal serum alanine aminotransferase levels for screening metabolic dysfunction-associated fatty liver disease.

Yang, Junli / Hou, Yeting / Zhang, Qiang / Wang, Yanfang

Journal of the Formosan Medical Association = Taiwan yi zhi

2023 Volume 122, Issue 10, Page(s) 1092–1093

MeSH term(s)	Humans ; Alanine Transaminase ; Non-alcoholic Fatty Liver Disease/diagnosis ; Liver/metabolism
Chemical Substances	Alanine Transaminase (EC 2.6.1.2)
Language	English
Publishing date	2023-05-23
Publishing country	Singapore
Document type	Letter ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	2096659-3
ISSN	1876-0821 ; 0929-6646
ISSN (online)	1876-0821
ISSN	0929-6646
DOI	10.1016/j.jfma.2023.05.013
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1041: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Expression and Prognostic Role of E2F2 in Hepatocellular Carcinoma.

Shen, Shen / Wang, Yanfang

International journal of general medicine

2021 Volume 14, Page(s) 8463–8472

Abstract: Introduction: Hepatocellular carcinoma (HCC) is a common clinical malignancy. Recent studies reported that E2F transcription factor 2 (E2F2) plays a significant role in tumor progression. However, its expression and biological function in HCC are still ... ...

Abstract	Introduction: Hepatocellular carcinoma (HCC) is a common clinical malignancy. Recent studies reported that E2F transcription factor 2 (E2F2) plays a significant role in tumor progression. However, its expression and biological function in HCC are still unclear. Therefore, we explored the relationship between E2F2 expression and tumor progression in HCC. Methods: In this study, we utilized some online tools to explore the E2F2 expression in pan-carcinoma and HCC. The association of E2F2 expression with the clinical characteristics and prognosis of HCC was further studied. In addition, we explored the co-expressed genes of E2F2 and mined the positively/negatively corrected significant genes and excavated the possible functions. Meanwhile, the hub gene set was constructed based on protein-protein interaction (PPI) network, and the relationship between E2F2 and immunity was discovered. Results: We observed that the expression level of E2F2 was generally upregulated in HCC. However, E2F2 expression was not significantly different between HCC and normal tissues in regard to the disease stage 4. Furthermore, we also observed the poor prognosis in patients with high E2F2 expression. The co-expressed genes of E2F2 were identified and further detected. Thereafter, we identified the positively/negatively corrected significant genes and constructed the hub gene network of E2F2 based on PPI network. We also found that E2F2 expression was positively correlated with the infiltration levels of CD4+ T, CD8+ T cells, macrophages, neutrophils, and dendritic cells. Conclusion: Our findings suggested that E2F2 could be a potential prognostic factor for HCC, which could provide a therapeutic target for the molecular treatment of HCC.
Language	English
Publishing date	2021-11-18
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2452220-X
ISSN	1178-7074
ISSN	1178-7074
DOI	10.2147/IJGM.S334033
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito