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  1. Artikel ; Online: Three-Portal Approach of Arthroscopy for Anterior Ankle Impingement Syndrome: A Propensity Score-Matched Analysis.

    Wang, Zeng-Liang / Cui, Lei / Li, Gui-Shi

    Orthopaedic surgery

    2021  Band 13, Heft 1, Seite(n) 53–62

    Abstract: Objective: To introduce a 3-portal approach of arthroscopic for anterior ankle impingement syndrome and to compare this method with 2-portal arthroscopy.: Methods: From July 2011 to April 2019, a total of 52 patients (30 females, 22 males) with ... ...

    Abstract Objective: To introduce a 3-portal approach of arthroscopic for anterior ankle impingement syndrome and to compare this method with 2-portal arthroscopy.
    Methods: From July 2011 to April 2019, a total of 52 patients (30 females, 22 males) with anterior ankle impingement syndrome underwent surgery with 2-portal approach (anterior medial and anterior lateral approach; N = 26) and modified 3-portal approach (anterior medial, anterior lateral, and an accessory anterior median approach; N = 26) of arthroscopic were recruited retrospectively after we performed a propensity score-matched analysis (PSMA). The mean age at operation time was 44.1 years (range from 22 years to 74 years) and the mean follow-up duration was more than two years (range from 2 years to 9 years). Clinical outcomes of all patients were evaluated according to the range of motion (ROM, dorsal flex angle), the American Orthopaedic Foot and Ankle Society lesser metatarsophalangeal interphalangeal scale (AOFAS), the visual analogue scale (VAS), and the operation time before and after the surgery.
    Results: During the follow-up period, both two groups indicated significant improvement in these function scores. Clinical assessment showed that for the 2-portal approach of arthroscopic the total average of AOFAS scores were significantly increased from preoperative 59.91 ± 5.281 points to postoperative 76.18 ± 1.471 points (P = 0.02), the VAS scores were significantly decreased from preoperative 7.64 ± 0.924 points to postoperative 4.18 ± 0.982 points (P = 0.04), and the dorsal flex angle was significantly increased from preoperative 12.27° ± 6.467° to postoperative 21.36° ± 3.931° at the last follow-up (P = 0.035). However, for the 3-portal approach of arthroscopic the total average of AOFAS scores were significantly increased from preoperative 48.64 ± 9.646 points to postoperative 79.18 ± 6.555 points (P = 0.015), the VAS scores were significantly decreased from preoperative 7.82 ± 0.751 points to postoperative 2.64 ± 1.629 points (P = 0.01), and the dorsal flex angle was significantly increased from preoperative 13.64° ± 7.775° to postoperative 20.45° ± 6.502° at the last follow-up (P = 0.045). There were no significant differences among the dorsal flex angle, the AOFAS scores, and the VAS scores between the two groups at the last follow-up (P > 0.05). Although the operation time of the 3-portal approach of arthroscopic (74.82 ± 18.395 min) was longer than that of the 2-portal approach of arthroscopic (92.55 ± 27.153 min), the difference was not significant (P > 0.05).
    Conclusion: Both the 2-portal and the 3-portal approach of arthroscopic provides almost the same satisfactory clinical outcomes for anterior ankle impingement syndrome, but we strongly suggest the 3-portal approach of arthroscopic which can supply greater joint contact area to treat advanced impingement syndrome for a good result.
    Mesh-Begriff(e) Adult ; Aged ; Ankle Injuries/surgery ; Arthroscopy/methods ; Female ; Humans ; Male ; Middle Aged ; Pain Measurement ; Propensity Score ; Retrospective Studies ; Surveys and Questionnaires ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2021-01-11
    Erscheinungsland Australia
    Dokumenttyp Comparative Study ; Journal Article
    ZDB-ID 2503162-4
    ISSN 1757-7861 ; 1757-7853 ; 1757-7861
    ISSN (online) 1757-7861 ; 1757-7853
    ISSN 1757-7861
    DOI 10.1111/os.12824
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: [Influence of acupuncture combined with rehabilitation therapy on limb motor function and serum cAMP and cGMP in patients with hemiplegia of cerebral ischemic stroke].

    Jing, Fu-Quan / Qin, Hu / Liu, Huan / Wang, Zeng-Liang

    Zhongguo zhen jiu = Chinese acupuncture & moxibustion

    2020  Band 40, Heft 6, Seite(n) 581–585

    Abstract: Objective: To evaluate the therapeutic effect of the combined treatment with balance acupuncture therapy and exercise re-learning rehabilitation therapy and the impact on serum cAMP and cGMP in the patients with hemiplegia of cerebral ischemic stroke.!## ...

    Abstract Objective: To evaluate the therapeutic effect of the combined treatment with balance acupuncture therapy and exercise re-learning rehabilitation therapy and the impact on serum cAMP and cGMP in the patients with hemiplegia of cerebral ischemic stroke.
    Methods: A total of 90 patients of hemiplegia of cerebral ischemic stroke were randomized into an observation group and a control group, 45 cases in each one. All of the patients in the two groups received health education, diet guidance, routine symptomatic treatment as well as exercise re-learning rehabilitation therapy. Additionally, in the observation group, balance acupuncture therapy was applied, in which, the acupoints on the
    Results: After treatment, FMA score was increased in the patients of either of the groups as compared with that before treatment (
    Conclusion: The balance acupuncture therapy combined with exercise re-learning rehabilitation effectively improves the motor function of the affected limb, relieves injury and regulate the levels of serum cAMP and cGMP in the patients with hemiplegia of ischemic stroke.
    Mesh-Begriff(e) Acupuncture Points ; Acupuncture Therapy ; Brain Ischemia/therapy ; Cyclic AMP/blood ; Cyclic GMP/blood ; Hemiplegia/therapy ; Humans ; Stroke/therapy ; Stroke Rehabilitation ; Treatment Outcome
    Chemische Substanzen Cyclic AMP (E0399OZS9N) ; Cyclic GMP (H2D2X058MU)
    Sprache Chinesisch
    Erscheinungsdatum 2020-06-15
    Erscheinungsland China
    Dokumenttyp Journal Article ; Randomized Controlled Trial
    ISSN 0255-2930
    ISSN 0255-2930
    DOI 10.13703/j.0255-2930.20190613-k0001
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  3. Artikel: A Novel Application of Unsupervised Machine Learning and Supervised Machine Learning-Derived Radiomics in Anterior Cruciate Ligament Rupture.

    Chen, De-Sheng / Wang, Tong-Fu / Zhu, Jia-Wang / Zhu, Bo / Wang, Zeng-Liang / Cao, Jian-Gang / Feng, Cai-Hong / Zhao, Jun-Wei

    Risk management and healthcare policy

    2021  Band 14, Seite(n) 2657–2664

    Abstract: Purpose: We aim to present an unsupervised machine learning application in anterior cruciate ligament (ACL) rupture and evaluate whether supervised machine learning-derived radiomics features enable prediction of ACL rupture accurately.: Patients and ... ...

    Abstract Purpose: We aim to present an unsupervised machine learning application in anterior cruciate ligament (ACL) rupture and evaluate whether supervised machine learning-derived radiomics features enable prediction of ACL rupture accurately.
    Patients and methods: Sixty-eight patients were reviewed. Their demographic features were recorded, radiomics features were extracted, and the input dataset was defined as a collection of demographic features and radiomics features. The input dataset was automatically classified by the unsupervised machine learning algorithm. Then, we used a supervised machine learning algorithm to construct a radiomics model. The
    Results: In total, 5 demographic features were recorded and 106 radiomics features were extracted. By applying the unsupervised machine learning algorithm, patients were divided into 5 groups. Group 5 had the highest incidence of ACL rupture and left knee involvement. There were significant differences in left knee involvement among the groups. Forty-three radiomics features were extracted using
    Conclusion: We validated the clinical application of unsupervised machine learning involving ACL rupture. Moreover, we found 7 radiomics features which were potential predictors for ACL rupture. The study indicated that radiomics could be a valuable method in the prediction of ACL rupture.
    Sprache Englisch
    Erscheinungsdatum 2021-06-23
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2495128-6
    ISSN 1179-1594
    ISSN 1179-1594
    DOI 10.2147/RMHP.S312330
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  4. Artikel: Unsupervised Machine Learning-Based Analysis of Clinical Features, Bone Mineral Density Features and Medical Care Costs of Rotator Cuff Tears.

    Wang, Tong-Fu / Chen, De-Sheng / Zhu, Jia-Wang / Zhu, Bo / Wang, Zeng-Liang / Cao, Jian-Gang / Feng, Cai-Hong / Zhao, Jun-Wei

    Risk management and healthcare policy

    2021  Band 14, Seite(n) 3977–3986

    Abstract: Purpose: We aim to present unsupervised machine learning-based analysis of clinical features, bone mineral density (BMD) features, and medical care costs of Rotator cuff tears (RCT).: Patients and methods: Fifty-three patients with RCT were reviewed, ...

    Abstract Purpose: We aim to present unsupervised machine learning-based analysis of clinical features, bone mineral density (BMD) features, and medical care costs of Rotator cuff tears (RCT).
    Patients and methods: Fifty-three patients with RCT were reviewed, the clinical features, BMD features, and medical care costs were collected and analyzed by descriptive statistics. Furtherly, unsupervised machine learning (UML) algorithm was used for dimensionality reduction and cluster analysis of the RCT data.
    Results: There were 26 males and 27 females. The patients were divided into four subgroups using the UML algorithm. There were significant differences among four subgroups regarding trauma exposure, full-thickness supraspinatus tendon tears, infraspinatus tendon tear, subscapularis tendon tear, BMD distribution, medial row anchors, lateral row anchors, total medical care costs, and consumables costs. We observed the highest frequency of trauma exposure, infraspinatus tendon tear, subscapularis tendon tear, osteoporosis, the highest number of medial row anchors, lateral row anchors, total medical care costs, and consumables costs in subgroup II.
    Conclusion: The unsupervised machine learning-based analysis of RCT can provide clinically meaningful classification, which shows good interpretability and contribute to a better understanding of RCT. The significance of the results is limited due to the small number of samples, a larger follow-up study is needed to confirm the encouraging results.
    Sprache Englisch
    Erscheinungsdatum 2021-09-22
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2495128-6
    ISSN 1179-1594
    ISSN 1179-1594
    DOI 10.2147/RMHP.S330555
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  5. Artikel ; Online: Postoperative Bone Marrow Lesions (BMLs) Are Associated with Pain Severity in Patients Undergoing Open Wedge High Tibial Osteotomy (OWHTO).

    Zhu, Bo / Wang, Tong-Fu / Chen, De-Sheng / Zhu, Jia-Wang / Wang, Zeng-Liang / Cao, Jian-Gang / Zhao, Jun-Wei

    BioMed research international

    2021  Band 2021, Seite(n) 9938037

    Abstract: The purpose of the study was to investigate the relationship between postoperative bone marrow lesions (BMLs) and pain severity in patients undergoing open wedge high tibial osteotomy (OWHTO). We reviewed the patients undergoing OWHTO between April 2018 ... ...

    Abstract The purpose of the study was to investigate the relationship between postoperative bone marrow lesions (BMLs) and pain severity in patients undergoing open wedge high tibial osteotomy (OWHTO). We reviewed the patients undergoing OWHTO between April 2018 and April 2020. The demographic and clinical data of patients were collected. Clinically, VAS and Knee injury and Osteoarthritis Outcome Score (KOOS) were used to assess pain level and functional outcomes of patients. The MRI Osteoarthritis Knee Score (MOAKS) was used to assess the total BMLs size in medial tibiofemoral (MTF), lateral tibiofemoral (LTF), and patellofemoral (PF) joints. 98 patients were enrolled in the study, including 57 male and 41 female patients. The VAS scores improved significantly from 6.1 ± 0.8 to 1.5 ± 0.9 (
    Mesh-Begriff(e) Aged ; Bone Marrow/diagnostic imaging ; Bone Marrow/pathology ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Osteotomy/adverse effects ; Pain Measurement ; Postoperative Period ; Severity of Illness Index ; Tibia/diagnostic imaging ; Tibia/surgery ; Treatment Outcome ; Visual Analog Scale
    Sprache Englisch
    Erscheinungsdatum 2021-07-07
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2021/9938037
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  6. Artikel ; Online: Platelet-rich plasma in arthroscopic rotator cuff repair.

    Zhao, Jia-Guo / Wang, Zeng-Liang / Zhao, Li

    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

    2015  Band 31, Heft 1, Seite(n) 9–10

    Mesh-Begriff(e) Arthroscopy ; Humans ; Platelet Transfusion/methods ; Rotator Cuff Injuries
    Sprache Englisch
    Erscheinungsdatum 2015-01
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 632528-2
    ISSN 1526-3231 ; 0749-8063
    ISSN (online) 1526-3231
    ISSN 0749-8063
    DOI 10.1016/j.arthro.2014.11.004
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  7. Artikel ; Online: Baicalin Attenuates Joint Pain and Muscle Dysfunction by Inhibiting Muscular Oxidative Stress in an Experimental Osteoarthritis Rat Model.

    Chen, De-Sheng / Cao, Jian-Gang / Zhu, Bo / Wang, Zeng-Liang / Wang, Tong-Fu / Tang, Jian-Jun

    Archivum immunologiae et therapiae experimentalis

    2018  Band 66, Heft 6, Seite(n) 453–461

    Abstract: Osteoarthritis (OA) is the most common degenerative joint disease, and causes major pain and disability in adults. It has been reported that muscle weakness and inflammation contribute to osteoarthritis development and progression. Oxidative stress plays ...

    Abstract Osteoarthritis (OA) is the most common degenerative joint disease, and causes major pain and disability in adults. It has been reported that muscle weakness and inflammation contribute to osteoarthritis development and progression. Oxidative stress plays important roles in muscle dysfunction and inflammation in osteomyelitis. Baicalin, the major active constituent of the isolated root of Scutellarialateriflora Georgi, has been shown to have anti-oxidative and anti-inflammatory effects. In this study, we evaluated the potential effects of baicalin on osteoarthritis. We established experimental osteoarthritis rat model, applied baicalin to the rats, and then explored the potential protective effect of baicalin on osteoarthritis severity, muscle dysfunction, and oxidative stress. Baicalin alleviated severity of OA in rats. Baicalin application attenuated muscle dysfunction in OA rats by increasing citrate synthase activity, myosin heavy chain IIa expression, and decreasing interleukin 6 production. Baicalin decreased muscular reactive oxygen species generation in OA rats. Baicalin inhibited nuclear factor erythroid-derived 2-like 2 expression in OA rats. Baicalin attenuated osteoarthritis in rat by inhibiting oxidative stress.
    Mesh-Begriff(e) Adult ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Arthralgia/drug therapy ; Flavonoids/therapeutic use ; Humans ; Joints/drug effects ; Joints/physiology ; Male ; Medicine, Chinese Traditional ; Models, Animal ; Muscles/drug effects ; Muscles/physiology ; Osteoarthritis/drug therapy ; Rats ; Rats, Sprague-Dawley ; Scutellaria/immunology
    Chemische Substanzen Anti-Inflammatory Agents, Non-Steroidal ; Flavonoids ; baicalin (347Q89U4M5)
    Sprache Englisch
    Erscheinungsdatum 2018-08-03
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 282209-x
    ISSN 1661-4917 ; 0004-069X
    ISSN (online) 1661-4917
    ISSN 0004-069X
    DOI 10.1007/s00005-018-0518-6
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  8. Artikel ; Online: Platelet-rich plasma in arthroscopic rotator cuff repair: a meta-analysis of randomized controlled trials.

    Zhao, Jia-Guo / Zhao, Li / Jiang, Yan-Xia / Wang, Zeng-Liang / Wang, Jia / Zhang, Peng

    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

    2015  Band 31, Heft 1, Seite(n) 125–135

    Abstract: Purpose: The purpose of this study was to appraise the retear rate and clinical outcomes of platelet-rich plasma use in patients undergoing arthroscopic full-thickness rotator cuff repair.: Methods: We searched the Cochrane Library, PubMed, and ... ...

    Abstract Purpose: The purpose of this study was to appraise the retear rate and clinical outcomes of platelet-rich plasma use in patients undergoing arthroscopic full-thickness rotator cuff repair.
    Methods: We searched the Cochrane Library, PubMed, and EMBASE databases for randomized controlled trials comparing the outcomes of arthroscopic rotator cuff surgery with or without the use of platelet-rich plasma. Methodological quality was assessed by the Detsky quality scale. When there was no high heterogeneity, we used a fixed-effects model. Dichotomous variables were presented as risk ratios (RRs) with 95% confidence intervals (CIs), and continuous data were measured as mean differences with 95% CIs. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used to assess the quality of evidence for each individual outcome.
    Results: Eight randomized controlled trials were included, with the sample size ranging from 28 to 88. Overall methodological quality was high. Fixed-effects analysis showed that differences were not significant between the 2 groups in retear rate (RR, 0.94; 95% CI, 0.70 to 1.25; P = .66), Constant score (mean difference, 1.12; 95% CI, -1.38 to 3.61; P = .38), and University of California at Los Angeles (UCLA) score (mean difference, -0.68; 95% CI, -2.00 to 0.65; P = .32). The strength of GRADE evidence was categorized respectively as low for retear, moderate for Constant score, and low for UCLA shoulder score.
    Conclusions: Our meta-analysis does not support the use of platelet-rich plasma in the arthroscopic repair of full-thickness rotator cuff tears over repairs without platelet-rich plasma because of similar retear rates and clinical outcomes.
    Level of evidence: Level II, meta-analysis of Level I and II randomized controlled trials.
    Mesh-Begriff(e) Arthroscopy ; Female ; Humans ; Platelet-Rich Plasma ; Randomized Controlled Trials as Topic ; Recurrence ; Rotator Cuff/surgery ; Rotator Cuff Injuries ; Rupture/surgery ; Wound Healing
    Sprache Englisch
    Erscheinungsdatum 2015-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Meta-Analysis ; Review
    ZDB-ID 632528-2
    ISSN 1526-3231 ; 0749-8063
    ISSN (online) 1526-3231
    ISSN 0749-8063
    DOI 10.1016/j.arthro.2014.08.008
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  9. Artikel: [Review on studying the early warning of influenza based on the data from Internet].

    Li, Rui / Wang, Zeng-liang / Zhang, Zhi-jie / Gao, Jie / Jiang, Qing-wu

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2013  Band 34, Heft 1, Seite(n) 101–103

    Mesh-Begriff(e) Humans ; Influenza, Human/prevention & control ; Information Storage and Retrieval ; Internet
    Sprache Chinesisch
    Erscheinungsdatum 2013-01
    Erscheinungsland China
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
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  10. Artikel ; Online: Risk patterns of subsequent primary cancers following esophagectomy in early-stage thoracic esophageal squamous cell cancer patients.

    Hu, Wen-Si / Liu, Zeng-Jun / Zhang, Jian-Bo / Wang, Zeng-Liang / Yang, Ning / Xu, Liang / Tian, Hui / Zhang, Pin-Liang

    Tumori

    2015  Band 101, Heft 3, Seite(n) 328–333

    Abstract: Aims and background: Subsequent primary cancers (SPCs) have been demonstrated to be the major causes of death among patients with thoracic esophageal squamous cell cancer (ESCC) negative for lymph node involvement. We designed this study to investigate ... ...

    Abstract Aims and background: Subsequent primary cancers (SPCs) have been demonstrated to be the major causes of death among patients with thoracic esophageal squamous cell cancer (ESCC) negative for lymph node involvement. We designed this study to investigate clinical characteristics and risk patterns of SPCs following esophagectomy in patients with early-stage thoracic ESCC.
    Methods: We retrospectively analyzed clinical factors in 512 patients with early-stage thoracic ESCC collected from 3 independent hospitals over a 10-year interval.
    Results: The overall standard incidence rate (SIR) of SPCs was 3.84 (95% confidence interval 2.98-4.95). The most common SPCs were head and neck cancers, lung cancer, and stomach cancer. The risk patterns of SPCs varied across organs. A 3-phase risk pattern with a U-shaped curve between 2 rising phases was seen for head and neck cancers, while for the other cancers, the risk patterns all displayed as an approximately linear upward trend. It was further noted that sex, smoking habits, and cancer histories among first-degree relatives were 3 significant independent risk factors in the development of SPCs.
    Conclusions: We observed significant associations between early-stage ESCC and SPCs arising from anatomically adjacent sites. The different risk patterns of SPCs indicated that follow-up strategies should be established accordingly in different organs at different times, with particularly close follow-up for head and neck cancers in the first 5 years and beyond 15 years after diagnosis of ESCC.
    Mesh-Begriff(e) Adult ; Aged ; Carcinoma, Squamous Cell/complications ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; China/epidemiology ; Esophageal Neoplasms/complications ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Esophageal Squamous Cell Carcinoma ; Esophagectomy ; Female ; Head and Neck Neoplasms/etiology ; Humans ; Lung Neoplasms/etiology ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; Neoplasms, Second Primary/epidemiology ; Neoplasms, Second Primary/etiology ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Stomach Neoplasms/etiology ; Time Factors
    Sprache Englisch
    Erscheinungsdatum 2015-04-30
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Multicenter Study
    ZDB-ID 280962-x
    ISSN 2038-2529 ; 0300-8916
    ISSN (online) 2038-2529
    ISSN 0300-8916
    DOI 10.5301/tj.5000285
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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