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  1. Book ; Thesis: MicroRNAs influence the migratory ability of human umbilical vein endothelial cells

    Wang, Zhaohui

    2021  

    Author's details vorgelegt von Zhaohui Wang
    Language English
    Size 76 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    HBZ-ID HT021410259
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Molecular Carbon Imides.

    Jiang, Wei / Wang, Zhaohui

    Journal of the American Chemical Society

    2022  Volume 144, Issue 33, Page(s) 14976–14991

    Abstract: The creation and development of new forms of nanocarbons have fundamentally transformed the scientific landscape in the past three decades. As new members of the nanocarbon family with accurate size, shape, and edge structure, molecular carbon imides ( ... ...

    Abstract The creation and development of new forms of nanocarbons have fundamentally transformed the scientific landscape in the past three decades. As new members of the nanocarbon family with accurate size, shape, and edge structure, molecular carbon imides (MCIs) have shown unexpected and unique properties. Particularly, the imide functionalization strategy has endowed these rylene-based molecular carbons with fascinating characteristics involving flexible syntheses, tailor-made structures, diverse properties, excellent processability, and good stability. This Perspective elaborates molecular design evolution to functional landscapes, and illustrative examples are given, including a promising library of multi-size and multi-dimensional MCIs with rigidly conjugated π-architectures, ranging from 1D nanoribbon imides and 2D nanographene imides to cross-dimensional MCIs. Although researchers have achieved substantial progress in using MCIs as functional components for exploration of charge transport, photoelectric conversion, and chiral luminescence performances, they are far from unleashing their full potential. Developing highly efficient and regioselective coupling/ring-closure reactions involving the formation of multiple C-C bonds and the annulation of electron-deficient aromatic units is crucial. Prediction by theory with the help of machine learning and artificial intelligence research along with reliable nanotechnology characterization will give an impetus to the blossom of related fields. Future investigations will also have to advance toward─or even focus on─the emerging potential functions, especially in the fields of chiral electronics and spin electronics, which are expected to open new avenues.
    MeSH term(s) Artificial Intelligence ; Electronics/methods ; Imides/chemistry ; Nanotechnology ; Nanotubes, Carbon
    Chemical Substances Imides ; Nanotubes, Carbon
    Language English
    Publishing date 2022-07-29
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.2c04642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Response to Comment on "EPR Evidence for Mechanistic Diversity of Cu(II)/Peroxygen Oxidation Systems by Tracing the Origin of DMPO Spin Adducts".

    Wang, Lingli / Wang, Zhaohui

    Environmental science & technology

    2022  Volume 56, Issue 19, Page(s) 14209–14210

    MeSH term(s) Electron Spin Resonance Spectroscopy ; Oxidation-Reduction ; Spin Trapping
    Language English
    Publishing date 2022-09-08
    Publishing country United States
    Document type Letter ; Comment
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.2c06016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Molecular Carbon Imides

    Jiang, Wei / Wang, Zhaohui

    Journal of the American Chemical Society. 2022 July 29, v. 144, no. 33

    2022  

    Abstract: The creation and development of new forms of nanocarbons have fundamentally transformed the scientific landscape in the past three decades. As new members of the nanocarbon family with accurate size, shape, and edge structure, molecular carbon imides ( ... ...

    Abstract The creation and development of new forms of nanocarbons have fundamentally transformed the scientific landscape in the past three decades. As new members of the nanocarbon family with accurate size, shape, and edge structure, molecular carbon imides (MCIs) have shown unexpected and unique properties. Particularly, the imide functionalization strategy has endowed these rylene-based molecular carbons with fascinating characteristics involving flexible syntheses, tailor-made structures, diverse properties, excellent processability, and good stability. This Perspective elaborates molecular design evolution to functional landscapes, and illustrative examples are given, including a promising library of multi-size and multi-dimensional MCIs with rigidly conjugated π-architectures, ranging from 1D nanoribbon imides and 2D nanographene imides to cross-dimensional MCIs. Although researchers have achieved substantial progress in using MCIs as functional components for exploration of charge transport, photoelectric conversion, and chiral luminescence performances, they are far from unleashing their full potential. Developing highly efficient and regioselective coupling/ring-closure reactions involving the formation of multiple C–C bonds and the annulation of electron-deficient aromatic units is crucial. Prediction by theory with the help of machine learning and artificial intelligence research along with reliable nanotechnology characterization will give an impetus to the blossom of related fields. Future investigations will also have to advance toward─or even focus on─the emerging potential functions, especially in the fields of chiral electronics and spin electronics, which are expected to open new avenues.
    Keywords artificial intelligence ; carbon ; electronics ; imides ; landscapes ; luminescence ; nanomaterials ; prediction ; regioselectivity
    Language English
    Dates of publication 2022-0729
    Size p. 14976-14991.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.2c04642
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: The spatiotemporal pattern of glypican coordinates primordial germ cell differentiation with ovary development.

    Liu, Xian / Li, Xin / Wang, Zhaohui

    iScience

    2023  Volume 27, Issue 1, Page(s) 108710

    Abstract: The establishment, proliferation, and differentiation of stem cells are coordinated with organ development and regulated by the signals in the microenvironment. Prior to gonad formation, how primordial germ cells (PGC) differentiate spatiotemporally to ... ...

    Abstract The establishment, proliferation, and differentiation of stem cells are coordinated with organ development and regulated by the signals in the microenvironment. Prior to gonad formation, how primordial germ cells (PGC) differentiate spatiotemporally to coordinate with gonadogenesis is unclear. In adult ovary, drosophila extracellular glypican Dally in germline stem cell (GSC) niche promotes BMP signaling to inhibit germline differentiation. Here we investigated the relation between the fate of PGC and the spatiotemporal pattern of glypican during ovary development. We found that Dally in ovarian soma assisted BMP signaling to prevent PGC from precocious differentiation. Dally's presence raises the "hurdle" for ecdysone peaks to eventually remove the transcription factor Kr and de-repress pro-differentiation factor, temporally postponing PGC differentiation until GSC niche establishment. The spatiotemporal glypican in somatic matrix assists PGC to integrate the ovarian local BMP and organismal steroid signals that coordinate PGC's program with organ/body development to maximize reproductive potential.
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2023.108710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Risk of Hepatitis B Virus Reactivation in Patients with Resolved Infection on Therapy with Corticosteroids and Conventional Synthesis Immunosuppressants for Kidney Disease: A Single-Center Analysis of 258 Patients.

    Han, Pingyang / Wang, Ziqiu / Wang, Zhaohui

    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology

    2023  Volume 34, Issue 10, Page(s) 1035–1040

    Abstract: Background/aims: The risk of hepatitis B virus reactivation in patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease has not been well described.!# ...

    Abstract Background/aims: The risk of hepatitis B virus reactivation in patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease has not been well described.
    Materials and methods: We performed a retrospective study on the risk of hepatitis B virus reactivation in patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease between January 2012 and December 2021 in the Department of Nephrology at Ruijin Hospital.
    Results: A total of 258 patients with a previously resolved hepatitis B virus infection [all treated with high-dose corticosteroids, of whom 192 were receiving corticosteroids combined with conventional synthesis immunosuppressant therapy, including cyclophosphamide (155), cyclosporine A (14), mycophenolate mofetil (14), and tacrolimus (9)] were enrolled. During a mean follow-up time of 21.66 months (range 9-70 months), hepatitis B virus reactivation was not observed in these patients.
    Conclusions: Among patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease, hepatitis B virus reactivation was not common and severe, suggesting that universal prophylaxis may not be justified or cost-effective in this clinical setting.
    MeSH term(s) Humans ; Hepatitis B virus/physiology ; Immunosuppressive Agents/therapeutic use ; Retrospective Studies ; Virus Activation ; Hepatitis B ; Kidney Diseases ; Adrenal Cortex Hormones/therapeutic use ; Adrenal Cortex Hormones/pharmacology ; Hepatitis B Surface Antigens ; Antiviral Agents/therapeutic use
    Chemical Substances Immunosuppressive Agents ; Adrenal Cortex Hormones ; Hepatitis B Surface Antigens ; Antiviral Agents
    Language English
    Publishing date 2023-09-04
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 1340275-4
    ISSN 2148-5607 ; 1300-4948
    ISSN (online) 2148-5607
    ISSN 1300-4948
    DOI 10.5152/tjg.2023.22511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Less is More: Underlying Mechanism of Zn Electrode Long-Term Stability using Sodium L-Ascorbate as Electrolyte Additive.

    Luo, Yuzhe / Yin, Jiayi / Chen, Peng / Wang, Bin / Xu, Jiangtao / Wang, Zhaohui / Guo, Kunkun

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2310824

    Abstract: Structured passivation layers and hydrated ... ...

    Abstract Structured passivation layers and hydrated Zn
    Language English
    Publishing date 2024-01-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202310824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Laser irradiation of photothermal precursors - a novel approach to produce carbon materials for supercapacitors.

    Tammela, Petter / Iurchenkova, Anna / Wang, Zhaohui / Strømme, Maria / Nyholm, Leif / Lindh, Jonas

    ChemSusChem

    2024  , Page(s) e202301471

    Abstract: A wide array of carbon materials finds extensive utility across various industrial applications today. Nonetheless, the production processes for these materials continue to entail elevated temperatures, necessitate the use of inert atmospheres, and often ...

    Abstract A wide array of carbon materials finds extensive utility across various industrial applications today. Nonetheless, the production processes for these materials continue to entail elevated temperatures, necessitate the use of inert atmospheres, and often involve the handling of aggressive and toxic chemicals. The prevalent method for large-scale carbon material production, namely the pyrolysis of waste biomass and polymers, typically unfolds within the temperature range of 500-700 °C under a nitrogen (N
    Language English
    Publishing date 2024-02-01
    Publishing country Germany
    Document type Journal Article
    ISSN 1864-564X
    ISSN (online) 1864-564X
    DOI 10.1002/cssc.202301471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Case report: A kidney metastasis from vulvar squamous cell carcinoma.

    He, Junwei / Xiao, Yuhe / Wang, Lu / Wang, Zhaohui / Pan, Jun / Bai, Zunguang

    Frontiers in oncology

    2024  Volume 13, Page(s) 1280531

    Abstract: Introduction: Distant metastases of vulvar SCC most commonly involve the lung, liver, bone, skin, and lymph nodes. Metastasis from vulvar SCC to the kidneys is extremely rare, with only one case reported in the literature to date.: Case presentation: ...

    Abstract Introduction: Distant metastases of vulvar SCC most commonly involve the lung, liver, bone, skin, and lymph nodes. Metastasis from vulvar SCC to the kidneys is extremely rare, with only one case reported in the literature to date.
    Case presentation: We report the case of a 53-year-old postmenopausal female patient was diagnosed with vulvar squamous cell carcinoma in an external hospital and following the diagnosis, she had been performed a vulvectomy for squamous cell carcinoma of the vulva, at that time, the patient had not undergone inguinal lymphadenectomy. In July 2019, she was admitted to our hospital due to upper right quadrant pain. An enhanced whole-body CT scan showed a mixed-density tumor of the right kidney with invasion into the right renal portal vein and multiple enlarged retroperitoneal lymph nodes. Positron emission tomography-computed tomography (PET - CT) scan showed a significantly increased radioactivity uptake in the tumor and enlarged lymph nodes, but PET-CT did not show abnormal enlargement of bilateral inguinal lymph nodes and no abnormal increase in radioactivity uptake. PET-CT examination did not show recurrence in terms of local of vulvar. These results led us to be gravely worried about possible renal carcinoma, so it was agreed upon to perform laparoscopic nephrectomy of the right kidney in the same month. Histology of the resected tumor confirmed it to be poorly differentiated squamous cell carcinoma with invasion consistent with metastatic vulvar carcinoma. Based on clinical history, radiological and histological facts, the patient was diagnosed with kidney metastasis from vulvar squamous cell carcinoma. Recovery from surgery went well and the patient was transferred to the oncology department and underwent a chemotherapy regimen consisting of paclitaxel and nedaplatin for further treatment. After 6 courses of chemotherapy. For a year after treatment, the patient had lived progression-free. Unfortunately, she died of tumor progression in July 2022.
    Conclusion: Although renal metastasis from vulvar SCC is rare, renal metastasis should be considered for the patient with a history of vulvar cancer, whenever a mass is identified in the kidney. Timely surgical removal of renal metastasis may prolong the survival time.
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1280531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Preparation, Modification, and Application of Ethylene-Chlorotrifluoroethylene Copolymer Membranes.

    Liao, Zhangbin / Wang, Qian / Zhou, Qiuyueming / Cui, Zhaoliang / Wang, Zhaohui / Drioli, Enrico

    Membranes

    2024  Volume 14, Issue 2

    Abstract: Ethylene-chlorotrifluoroethylene (ECTFE) was first commercialized by DuPont in 1974. Its unique chemical structure gives it high heat resistance, mechanical strength, and corrosion resistance. But also due to these properties, it is difficult to prepare ... ...

    Abstract Ethylene-chlorotrifluoroethylene (ECTFE) was first commercialized by DuPont in 1974. Its unique chemical structure gives it high heat resistance, mechanical strength, and corrosion resistance. But also due to these properties, it is difficult to prepare a membrane from it by the nonsolvent-induced phase separation (NIPS) method. However, it can be prepared as a microfiltration membrane using the thermally induced phase separation (TIPS) method at certain temperatures and with the selection of suitable solvents, and the use of green solvents is receiving increasing attention from researchers. The surface wettability of ECTFE membranes usually needs to be modified before use to strengthen its performance to meet the application requirements, usually by graft modification and surface oxidation techniques. This paper provides an overview of the structure of ECTFE and its preparation and modification methods, as well as recent advances in its application areas and prospects for the future methods of preparing high-performance ECTFE membranes.
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2614641-1
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes14020042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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