Article: Alzheimer's disease biomarker utilization at first referral enhances differential diagnostic precision with simultaneous exclusion of Creutzfeldt-Jakob disease.
Alzheimer's & dementia (Amsterdam, Netherlands)
2024 Volume 16, Issue 1, Page(s) e12548
Abstract: Most suspected Creutzfeldt-Jakob disease (CJD) cases are eventually diagnosed with other disorders. We assessed the utility of investigating Alzheimer's disease (AD) biomarkers and neurofilament light (NfL) in patients when CJD is suspected. The study ... ...
| Abstract | Most suspected Creutzfeldt-Jakob disease (CJD) cases are eventually diagnosed with other disorders. We assessed the utility of investigating Alzheimer's disease (AD) biomarkers and neurofilament light (NfL) in patients when CJD is suspected. The study cohort consisted of cerebrospinal fluid (CSF) samples referred for CJD biomarker screening wherein amyloid beta 1-42 (Aβ1-42), phosphorylated tau 181 (p-tau181), and total tau (t-tau) could be assessed via Elecsys immunoassays ( |
|---|---|
| Language | English |
| Publishing date | 2024-02-13 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 2832898-X |
| ISSN | 2352-8729 |
| ISSN | 2352-8729 |
| DOI | 10.1002/dad2.12548 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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