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  1. Article ; Online: Signal, Not Poison—Screening Mint Essential Oils for Weed Control Leads to Horsemint

    Sarheed, Mohammed / Schärer, Hans-Jakob / Wang-Müller, Qiyan / Flury, Pascale / Maes, Chloé / Genva, Manon / Fauconnier, Marie-Laure / Nick, Peter

    Agriculture. 2023 Mar. 18, v. 13, no. 3

    2023  

    Abstract: Weed control tries to suppress competitors for a crop and often relies on differential intoxication, making use of differences in uptake, development, or metabolism. We explored the possibility of using natural signals to shift competition in favour of ... ...

    Abstract Weed control tries to suppress competitors for a crop and often relies on differential intoxication, making use of differences in uptake, development, or metabolism. We explored the possibility of using natural signals to shift competition in favour of the crop. Using the competitive horsemint (Mentha longifolia) as a paradigm, we showed that essential oils from certain mint species suppress the seedling development of different target species in a specific and efficient manner. The specificity concerned both the donor and the receptor. We demonstrated further that the effect of horsemint oil was specific for actin filaments, and not for microtubules. Since the elimination of actin will impair auxin transport, which is essential for root regeneration in vegetatively propagating weeds, we tested the efficacy of horsemint essential oil in combination with a slow-release carrier against field bindweed (Convolvulus arvensis), a pertinent weed in organic cereal production. We observed that the development of this weed can be specifically blocked, especially if the carrier is worked into the soil. We propose that allelopathic interactions, often relying on manipulative chemical signalling, harbour significant potential for organic weed control.
    Keywords Convolvulus arvensis ; Mentha longifolia ; actin ; agriculture ; auxins ; essential oils ; metabolism ; microtubules ; oils ; poisoning ; seedlings ; soil ; weed control ; weeds
    Language English
    Dates of publication 2023-0318
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2651678-0
    ISSN 2077-0472
    ISSN 2077-0472
    DOI 10.3390/agriculture13030712
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Innovation in agroecological and organic farming systems

    Niggli, Urs / Wang-Müller, Qiyan / Willer, Helga / Fuchs, Jacques

    2021  

    Abstract: In light of major ongoing environmental damage and the destruction of natural resources, developing a truly sustainable mode of agricultural production is of great importance. Among different ways to reduce trade-offs between ecological sustainability ... ...

    Abstract In light of major ongoing environmental damage and the destruction of natural resources, developing a truly sustainable mode of agricultural production is of great importance. Among different ways to reduce trade-offs between ecological sustainability and productivity, we present the approaches taken by agro-ecological and organic farmers. Both fall within the narrative of ecological intensification. According to finding of many previous scientific meta-analyses, both have a great potential to reduce environmental pollution. However, these very positive effects unfortunately result in lower yields. These could be compensated for by changing people's eating habits (e.g. less food waste, less meat consumption from concentrate-fed livestock). However, since global developments and trends are moving in exactly the opposite direction, this paper examines the possibilities of improving the yields of low-input farming systems through scientific research and the outlook for finding new productive solutions. Here we outline the significant potential in the redesign and differentiation of farms and fields including landscapes, in digitalization, the promotion of low-input breeding programs, high quality recycling of organic matter, and non-chemical crop protection.
    Keywords "Organics" in general
    Subject code 910
    Language English
    Publishing country dk
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Anti-microtubule activity of the traditional Chinese medicine herb Northern Ban Lan (Isatis tinctoria) leads to glucobrassicin.

    Guan, Pingyin / Zhou, Jianning / Girel, Sergey / Zhu, Xin / Schwab, Marian / Zhang, Kunxi / Wang-Müller, Qiyan / Bigler, Laurent / Nick, Peter

    Journal of integrative plant biology

    2021  Volume 63, Issue 12, Page(s) 2058–2074

    Abstract: Traditional Chinese medicine (TCM) belongs to the most elaborate and extensive systems of plant-based healing. The herb Northern Ban Lan (Isatis tinctoria) is famous for its antiviral and anti-inflammatory activity. Although numerous components isolated ... ...

    Abstract Traditional Chinese medicine (TCM) belongs to the most elaborate and extensive systems of plant-based healing. The herb Northern Ban Lan (Isatis tinctoria) is famous for its antiviral and anti-inflammatory activity. Although numerous components isolated from I. tinctoria have been characterized so far, their modes of action have remained unclear. Here, we show that extracts from I. tinctoria exert anti-microtubular activity. Using time-lapse microscopy in living tobacco BY-2 (Nicotiana tabacum L. cv Bright Yellow 2) cells expressing green fluorescent protein-tubulin, we use activity-guided fractionation to screen out the biologically active compounds of I. tinctoria. Among 54 fractions obtained from either leaves or roots of I. tinctoria by methanol (MeOH/H
    MeSH term(s) Glucosinolates ; HeLa Cells ; Humans ; Indoles ; Isatis/chemistry ; Medicine, Chinese Traditional ; Microtubules
    Chemical Substances Glucosinolates ; Indoles ; glucobrassicin (EA6EH0IU89)
    Language English
    Publishing date 2021-11-10
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 2130095-1
    ISSN 1744-7909 ; 1672-9072
    ISSN (online) 1744-7909
    ISSN 1672-9072
    DOI 10.1111/jipb.13177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Anti‐microtubule activity of the traditional Chinese medicine herb Northern Ban Lan (Isatis tinctoria) leads to glucobrassicin

    Guan, Pingyin / Zhou, Jianning / Girel, Sergey / Zhu, Xin / Schwab, Marian / Zhang, Kunxi / Wang‐Müller, Qiyan / Bigler, Laurent / Nick, Peter

    Journal of integrative plant biology. 2021 Dec., v. 63, no. 12

    2021  

    Abstract: Traditional Chinese medicine (TCM) belongs to the most elaborate and extensive systems of plant‐based healing. The herb Northern Ban Lan (Isatis tinctoria) is famous for its antiviral and anti‐inflammatory activity. Although numerous components isolated ... ...

    Abstract Traditional Chinese medicine (TCM) belongs to the most elaborate and extensive systems of plant‐based healing. The herb Northern Ban Lan (Isatis tinctoria) is famous for its antiviral and anti‐inflammatory activity. Although numerous components isolated from I. tinctoria have been characterized so far, their modes of action have remained unclear. Here, we show that extracts from I. tinctoria exert anti‐microtubular activity. Using time‐lapse microscopy in living tobacco BY‐2 (Nicotiana tabacum L. cv Bright Yellow 2) cells expressing green fluorescent protein‐tubulin, we use activity‐guided fractionation to screen out the biologically active compounds of I. tinctoria. Among 54 fractions obtained from either leaves or roots of I. tinctoria by methanol (MeOH/H₂O 8:2), or ethyl acetate extraction, one specific methanolic root fraction was selected, because it efficiently and rapidly eliminated microtubules. By combination of further purification with ultra‐high‐performance liquid chromatography and high‐resolution tandem mass spectrometry most of the bioactivity could be assigned to the glucosinolate compound glucobrassicin. Glucobrassicin can also affect microtubules and induce apoptosis in HeLa cells. In the light of these findings, the antiviral activity of Northern Ban Lan is discussed in the context of microtubules being hijacked by many viral pathogens for cell‐to‐cell spread.
    Keywords Isatis tinctoria ; Nicotiana tabacum ; Oriental traditional medicine ; anti-inflammatory activity ; antiviral properties ; apoptosis ; ethyl acetate ; fluorescence ; fractionation ; glucobrassicin ; medicinal plants ; methanol ; microscopy ; microtubules ; tandem mass spectrometry ; tobacco ; ultra-performance liquid chromatography
    Language English
    Dates of publication 2021-12
    Size p. 2058-2074.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2130095-1
    ISSN 1744-7909 ; 1672-9072
    ISSN (online) 1744-7909
    ISSN 1672-9072
    DOI 10.1111/jipb.13177
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: The genus Boschniakia in China: An ethnopharmacological and phytochemical review.

    Zhang, Le / Zhao, Yunshan / Wang, Zhipeng A / Wei, Kunhua / Qiu, Bin / Zhang, Chunhong / Wang-Müller, QiYan / Li, Minhui

    Journal of ethnopharmacology

    2016  Volume 194, Page(s) 987–1004

    Abstract: Ethnopharmacological relevance: As a group of important medicine plants, Boschniakia rossica (Cham. et Schltdl) Fedtsch. and B. himalaica Hook.f.et Thoms, which are the only two species in the genus Boschniakia (Orobanchaceae), have long been used in ... ...

    Abstract Ethnopharmacological relevance: As a group of important medicine plants, Boschniakia rossica (Cham. et Schltdl) Fedtsch. and B. himalaica Hook.f.et Thoms, which are the only two species in the genus Boschniakia (Orobanchaceae), have long been used in traditional Chinese medicine for their multiple therapeutic uses related to enhanced renal function, erectile dysfunction, defaecate and hepatoprotective. Additionally, the two species are also used as dietary supplements in wine, cosmetics, and other healthy food.
    Aim of the review: By providing comprehensive information and data of genus Boschniakia on botany, traditional medicinal uses, phytochemistry, pharmacological research and toxicology, this review aims to summary the group of natural compounds from Boschniakia discovered so far. The other aims are to reference research findings of their biological activities and functions in medicine, physiology, and cell biology to highlight the compound candidates which can be used for further drug discovery in several pharmaceutical areas including antioxidation, anticancer, anti-inflammation, anti-senile, and immunology.
    Materials and methods: All of the available information on B. rossica and B. himalaica was collected from the electronic resources (such as PubMed, SciFinder Scholar, CNKI, TPL (www.theplantlist.org), Google Scholar, Baidu Scholar, and Web of Science).
    Results: After a comprehensive analysis of the literatures from available online sources, the results show that both species of genus Boschniakia are valuable and popular herbal medicines with potentials to cure various ailments. The phytochemical studies revealed that the chemical compositions of this genus were mainly iridoid glycosides and phenylpropanoid glycosides. To date, 112 compounds have been isolated from the genus, while their crude extracts and purified compounds have been found to possess a wide range of biological activities including anti-senile, antitumor and anticancer, anti-inflammatory, protecting liver, boost memory, anti-oxidation, anti-lipid peroxidative, and antiviral activities.
    Conclusions: The existing traditional uses of the genus Boschniakia have been evaluated, and the properties of the genus are summarized based on botany, phytochemistry, pharmacological research, and toxicology. This review aims to introduce the utilization and application of the genus Boschniakia to modern drug discovery, traditional medicinal plant utilization, herbal species conservation, and the development of medicinal and health-maintaining products.
    MeSH term(s) China ; Ethnopharmacology/methods ; Humans ; Medicine, Chinese Traditional/methods ; Orobanchaceae/chemistry ; Phytochemicals/pharmacology ; Phytochemicals/therapeutic use ; Phytotherapy/methods ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Plants, Medicinal/chemistry
    Chemical Substances Phytochemicals ; Plant Extracts
    Language English
    Publishing date 2016-12-24
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2016.10.051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Differences in copper accumulation and copper stress between eight populations of Haumaniastrum katangense

    Peng, Hongyun / Wang-Müller, Qiyan / Witt, Timo / Malaisse, François / Küpper, Hendrik

    Environmental and experimental botany. 2012 July, v. 79

    2012  

    Abstract: Haumaniastrum katangense is well known as the “copper flower” of the Katangan Copper Belt. Few studies, however, are available on the physiology of this remarkable plant, including questions like stress responses and population-dependent differences. In ... ...

    Abstract Haumaniastrum katangense is well known as the “copper flower” of the Katangan Copper Belt. Few studies, however, are available on the physiology of this remarkable plant, including questions like stress responses and population-dependent differences. In the current study, we compared the response to copper for eight populations of this species in terms of copper accumulation, copper resistance, and various physiological parameters that might change under copper toxicity stress (biophysics of photosynthesis, growth, chlorophylls and carotenoids). Among six populations growing well under experimental conditions, three were found to be copper sensitive in terms of a strong inhibition of growth by 10μM copper, while the other three were rather resistant. As the most prominent copper tolerance associated difference, copper resistant populations (as judged by their growth, photosynthetic activity and pigmentation) showed a decrease of iron accumulation in response to increased copper supply, while copper sensitive populations increased their Fe accumulation in response under these conditions. Copper sensitive populations showed the expected loss of pigments under copper toxicity stress, while two of the three copper tolerant populations even showed an enhancement of chlorophylls and violaxanthin in response to toxic copper. Also for other pigments population-specific differences in copper response were found, but they did not correlate with copper tolerance. Photosynthesis biophysics was affected by copper stress like in other species, no clearly tolerance/population-specific differences were found.
    Keywords biophysics ; chlorophyll ; copper ; flowers ; photosynthesis ; plant physiology ; population growth ; stress response ; toxicity ; violaxanthin
    Language English
    Dates of publication 2012-07
    Size p. 58-65.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 195968-2
    ISSN 0098-8472
    ISSN 0098-8472
    DOI 10.1016/j.envexpbot.2011.12.015
    Database NAL-Catalogue (AGRICOLA)

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